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dipyridamole and Stomach Neoplasms

dipyridamole has been researched along with Stomach Neoplasms in 7 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
"Twenty-eight patients with advanced gastric cancer were treated with the simultaneous continuous intravenous (i."2.69Treatment of advanced gastric cancer with 5-fluorouracil and cisplatin in combination with dipyridamole. ( Baba, H; Emi, Y; Kohnoe, S; Maehara, Y; Sugimachi, K; Takahashi, I, 1998)
"Stomatitis was observed in 44/78 (56%) courses."2.67A phase I trial of 5-fluorouracil, leucovorin, and dipyridamole given by concurrent 120-h continuous infusions. ( Alberti, D; Arzoomanian, RZ; Bailey, H; Grem, JL; Spriggs, DR; Tombes, MB; Tutsch, KD; Wilding, G, 1992)
" The adverse effects related to the DP infusion were flushing, headache, nausea and upper abdominal discomfort, all of a low grade."2.67Dipyridamole combination chemotherapy can be used safely in treating gastric cancer patients. ( Emi, Y; Kohnoe, S; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K, 1991)
"Two cases of Toxic Epidermal Necrolysis, with a previous history of drugs intake, and associated to a lymphoma and to a chronic lymphoid leukemia, are presented."1.29[Toxic epidermal necrolysis associated with lymphoproliferative syndromes. Anatomo-clinical study. Presentation of 2 cases]. ( Aguado Santos, A; Gomez Duaso, AJ; Ortiz Reina, S; Sanz Asenjo, A; Seoane Leston, JM, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saitoh, M1
Nagai, K1
Nakagawa, K1
Yamamura, T1
Yamamoto, S1
Nishizaki, T1
Ito, S1
Hirono, S1
Seoane Leston, JM1
Gomez Duaso, AJ1
Sanz Asenjo, A1
Ortiz Reina, S1
Aguado Santos, A1
Kohnoe, S2
Maehara, Y2
Takahashi, I1
Emi, Y2
Baba, H1
Sugimachi, K2
Bailey, H1
Wilding, G1
Tutsch, KD1
Arzoomanian, RZ1
Alberti, D1
Tombes, MB1
Grem, JL1
Spriggs, DR1
Sakaguchi, Y1
Kusumoto, T1
Shchepotin, IB1
Chernyĭ, VA1
Grinevich, IuA1
Korobko, VB1
Kamenets, LIa1
Bendiug, GD1
Chernenko, OD1

Trials

3 trials available for dipyridamole and Stomach Neoplasms

ArticleYear
Treatment of advanced gastric cancer with 5-fluorouracil and cisplatin in combination with dipyridamole.
    International journal of oncology, 1998, Volume: 13, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dipyridamole; Female; Fluoro

1998
A phase I trial of 5-fluorouracil, leucovorin, and dipyridamole given by concurrent 120-h continuous infusions.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Dose-Response Relationshi

1992
Dipyridamole combination chemotherapy can be used safely in treating gastric cancer patients.
    Anti-cancer drugs, 1991, Volume: 2, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Doxoru

1991

Other Studies

4 other studies available for dipyridamole and Stomach Neoplasms

ArticleYear
Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.
    Biochemical pharmacology, 2004, May-15, Volume: 67, Issue:10

    Topics: Adenine; Adenosine; Adenylate Kinase; Aminoimidazole Carboxamide; Apoptosis; Caspase Inhibitors; Dip

2004
[Two cases with microangiopathic hemolytic anemia caused by anti-cancer drugs who improved rapidly after administration of aspirin and dipyridamole].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1982, Volume: 23, Issue:5

    Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Agents; Aspirin; Chromomycin A3; Dipyridamole; Female

1982
[Toxic epidermal necrolysis associated with lymphoproliferative syndromes. Anatomo-clinical study. Presentation of 2 cases].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1993, Volume: 94, Issue:5

    Topics: Anesthetics; Dipyridamole; Fatal Outcome; Female; Humans; Insulin; Leukemia, Lymphocytic, Chronic, B

1993
[Intensive preoperative gamma teletherapy combined with endogenous interferon induction in the treatment of stomach cancer].
    Vrachebnoe delo, 1990, Issue:11

    Topics: Combined Modality Therapy; Critical Care; Dipyridamole; Gamma Rays; Humans; Interferon Inducers; Pre

1990