dipyridamole has been researched along with Scleroderma, Systemic in 15 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "atheromatous coronary disease, dilated cardiomyopathy, scleroderma, sarcoidosis) and in patients who had undergone heart transplantation." | 2.37 | [Coronary reserve: a dynamic evaluation of coronary circulation]. ( Foult, JM; Nitenberg, A, 1987) |
| "Myocardial involvement in systemic sclerosis may be caused, at least in part, by myocardial ischemia due to functional or structural abnormalities of small coronary arteries or arterioles." | 1.27 | [Myocardial microvascularization in scleroderma]. ( Amor, B; Degeorges, M; Devaux, JY; Guerin, F; Kahan, A; Menkes, CJ; Nitenberg, A; Weber, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahaleh, MB | 1 |
| Osborn, I | 1 |
| Leroy, EC | 1 |
| Beckett, VL | 1 |
| Conn, DL | 1 |
| Fuster, V | 1 |
| Osmundson, PJ | 1 |
| Strong, CG | 1 |
| Chao, EY | 1 |
| Chesebro, JH | 1 |
| O'Fallon, WM | 1 |
| Sowemimo-Coker, SO | 1 |
| Kovacs, IB | 1 |
| Turner, P | 1 |
| Kirby, JD | 1 |
| Bogdanov, AP | 2 |
| Samoĭlenko, AE | 1 |
| Moiseev, SV | 2 |
| Guseva, NG | 3 |
| Samoĭlenko, LE | 1 |
| Pshenitsyn, AI | 1 |
| Pasha, SP | 1 |
| Sergienko, VB | 1 |
| Omote, A | 1 |
| Muramatsu, M | 1 |
| Sugimoto, Y | 1 |
| Hosono, S | 1 |
| Murakami, R | 1 |
| Tanaka, H | 1 |
| Watanabe, Y | 1 |
| Sano, H | 1 |
| Kato, K | 1 |
| Fisher, RS | 1 |
| Cohen, S | 1 |
| Poltyrev, AS | 1 |
| Alekseev, VI | 1 |
| Anikina, NV | 1 |
| Shcherbakov, AB | 1 |
| Kahan, A | 5 |
| Amor, B | 5 |
| Menkès, CJ | 5 |
| Nitenberg, A | 4 |
| Foult, JM | 4 |
| Grossman, JA | 1 |
| Barrall, DT | 1 |
| Dennison, A | 1 |
| Lally, EV | 1 |
| Devaux, JY | 4 |
| Weber, S | 2 |
| Guerin, F | 2 |
| Degeorges, M | 2 |
| Venot, A | 1 |
| Roucayrol, JC | 2 |
| Perennec, J | 2 |
| Blanchet, F | 1 |
| Lutfalla, G | 1 |
1 review available for dipyridamole and Scleroderma, Systemic
| Article | Year |
|---|---|
[Coronary reserve: a dynamic evaluation of coronary circulation].
Topics: Cardiomyopathy, Dilated; Coronary Circulation; Coronary Disease; Dipyridamole; Heart Diseases; Heart | 1987 |
2 trials available for dipyridamole and Scleroderma, Systemic
| Article | Year |
|---|---|
Trial of platelet-inhibiting drug in scleroderma. Double-blind study with dipyridamole and aspirin.
Topics: Aspirin; Biomechanical Phenomena; Blood Coagulation; Blood Platelets; Clinical Trials as Topic; Dipy | 1984 |
[Correction of microcirculatory disorders in rheumatic diseases].
Topics: Administration, Oral; Clinical Trials as Topic; Dextrans; Dipyridamole; Disseminated Intravascular C | 1985 |
12 other studies available for dipyridamole and Scleroderma, Systemic
| Article | Year |
|---|---|
Elevated levels of circulating platelet aggregates and beta-thromboglobulin in scleroderma.
Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Dipyridamole; Female; Humans; Male; Platelet Aggregat | 1982 |
An improved filtration rate for measuring red cell deformability.
Topics: Dipyridamole; Erythrocytes; Hematocrit; Humans; Pentoxifylline; Raynaud Disease; Scleroderma, System | 1984 |
[Myocardial scintigraphy with thallium-201 in the diagnosis of cardiac involvement in systemic scleroderma].
Topics: Adult; Aged; Dipyridamole; Female; Heart; Humans; Male; Middle Aged; Myocardial Ischemia; Radionucli | 1995 |
[Myocardial tomoscintigraphy with 201Tl in the diagnosis of cardiac involvement in systemic scleroderma].
Topics: Adult; Aged; Cardiomyopathies; Chronic Disease; Dipyridamole; Echocardiography; Electrocardiography; | 1996 |
Myeloperoxidase-specific anti-neutrophil cytoplasmic autoantibodies -- related scleroderma renal crisis treated with double-filtration plasmapheresis.
Topics: Acute Kidney Injury; Antibodies, Antineutrophil Cytoplasmic; Anticoagulants; Autoimmune Diseases; Bi | 1997 |
Disorders of the lower esophageal sphincter.
Topics: Acetylcholine; Chagas Disease; Dipyridamole; Esophageal Achalasia; Esophageal and Gastric Varices; E | 1975 |
[Physiopathogeny of sclerodermal cardiomyopathy].
Topics: Cardiomyopathies; Coronary Circulation; Coronary Vessels; Dipyridamole; Humans; Scleroderma, Systemi | 1988 |
Successful combined medical and surgical treatment of a lower extremity sclerodermal ulcer.
Topics: Aged; Aspirin; Combined Modality Therapy; Debridement; Dipyridamole; Etidronic Acid; Female; Humans; | 1988 |
[Myocardial microvascularization in scleroderma].
Topics: Coronary Circulation; Coronary Vessels; Dipyridamole; Heart; Humans; Microcirculation; Radionuclide | 1988 |
Pharmacodynamic effect of dipyridamole on thallium-201 myocardial perfusion in progressive systemic sclerosis with diffuse scleroderma.
Topics: Adult; Aged; Dipyridamole; Female; Heart; Humans; Male; Middle Aged; Radioisotopes; Scleroderma, Sys | 1986 |
Reduced coronary flow and resistance reserve in primary scleroderma myocardial disease.
Topics: Adult; Angiography; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Coronary Circulation; | 1986 |
Decreased coronary reserve in primary scleroderma myocardial disease.
Topics: Adult; Cardiomyopathies; Coronary Circulation; Coronary Vessels; Dipyridamole; Female; Hemodynamics; | 1985 |