dipyridamole has been researched along with Rectal Neoplasms in 3 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Rectal Neoplasms: Tumors or cancer of the RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In HCT 116 cells, a human colon cancer cell line, the levels of thymidine (0." | 1.27 | Augmentation of methotrexate cytotoxicity in human colon cancer cells achieved through inhibition of thymidine salvage by dipyridamole. ( Fischer, PH; Pangallo, CA; Van Mouwerik, TJ; Willson, JK, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dollinger, MR | 1 |
| Krakoff, IH | 1 |
| Van Mouwerik, TJ | 1 |
| Pangallo, CA | 1 |
| Willson, JK | 1 |
| Fischer, PH | 1 |
| Wadler, S | 1 |
| Subar, M | 1 |
| Green, MD | 1 |
| Wiernik, PH | 1 |
| Muggia, FM | 1 |
3 other studies available for dipyridamole and Rectal Neoplasms
| Article | Year |
|---|---|
Hemolysis induced by 6-N-hydroxylaminopurine riboside, an adenosine analogue.
Topics: Adenosine; Adult; Bilirubin; Blood Cell Count; Breast Neoplasms; Dipyridamole; Erythrocytes; Female; | 1975 |
Augmentation of methotrexate cytotoxicity in human colon cancer cells achieved through inhibition of thymidine salvage by dipyridamole.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Synergism; Guanine; Humans; Hypoxant | 1987 |
Phase II trial of oral methotrexate and dipyridamole in colorectal carcinoma.
Topics: Adenocarcinoma; Administration, Oral; Aged; Colonic Neoplasms; Dipyridamole; Drug Evaluation; Drug T | 1987 |