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dipyridamole and Peripheral Vascular Diseases

dipyridamole has been researched along with Peripheral Vascular Diseases in 23 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Peripheral Vascular Diseases: Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.

Research Excerpts

ExcerptRelevanceReference
"Dipyridamole nuclear myocardial perfusion test is a safe and effective alternative to exercise nuclear perfusion testing for detecting myocardial ischemia."7.71Dipyridamole-induced ST-segment elevation indicative of transmural myocardial ischemia--a case report. ( Chaudhry, K; Pillai, N; Rachko, M; Safi, AM; Stein, RA, 2001)
"Using the key terms acute coronary syndrome, atherothrombosis, ischemic stroke, myocardial infarction, MI, peripheral arterial disease, TIA, transient ischemic attack, unstable angina,aspirin,ticlopidine,dipyridamole, and clopidogrel, we searched the MEDLINE database as well as the trial register of the Cochrane Groups to identify studies published from 1960 to August 2004."4.82Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease. ( Anand, SS; Tran, H, 2004)
"Dipyridamole nuclear myocardial perfusion test is a safe and effective alternative to exercise nuclear perfusion testing for detecting myocardial ischemia."3.71Dipyridamole-induced ST-segment elevation indicative of transmural myocardial ischemia--a case report. ( Chaudhry, K; Pillai, N; Rachko, M; Safi, AM; Stein, RA, 2001)
"For this update the Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched June 2014) and the Cochrane Central Register of Controlled Trials (CENTRAL) (2014, Issue 5)."2.52Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery. ( Acosta, S; Bedenis, R; Lethaby, A; Maxwell, H; Prins, MH, 2015)
"Aspirin therapy was associated with a reduction in the secondary outcome of nonfatal stroke (52 of 2823 vs 76 of 2446; RR, 0."2.45Aspirin for the prevention of cardiovascular events in patients with peripheral artery disease: a meta-analysis of randomized trials. ( Berger, JS; Hiatt, WR; Kittelson, JM; Krantz, MJ, 2009)
"We searched the Cochrane Peripheral Vascular Diseases Group's trials register (last searched April 2004), the Cochrane Central Register of Controlled trials (CENTRAL Issue 2, 2004), MEDLINE and EMBASE (last searched June 2004)."2.43Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment. ( Büller, HR; Dörffler-Melly, J; Koopman, MM; Prins, MH, 2005)
"Dipyridamole treatment quickly restored ischaemic hindlimb blood flow, increased vascular density and cell proliferation, and enhanced collateral artery perfusion compared with control treatments."1.36Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway. ( Branch, B; Hood, J; Illum, S; Kevil, CG; Pardue, S; Patel, RP; Pattillo, CB; Teng, X; Thoma, S; Venkatesh, PK, 2010)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (47.83)18.2507
2000's10 (43.48)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bedenis, R1
Lethaby, A1
Maxwell, H1
Acosta, S1
Prins, MH2
Berger, JS1
Krantz, MJ1
Kittelson, JM1
Hiatt, WR1
Takagi, H1
Umemoto, T1
Venkatesh, PK1
Pattillo, CB1
Branch, B1
Hood, J1
Thoma, S1
Illum, S1
Pardue, S1
Teng, X1
Patel, RP1
Kevil, CG1
Dörffler-Melly, J2
Schmidli, J1
Mahler, F1
Moura, L1
Zamorano, J1
de Isla, LP1
Almeria, C1
Rodrigo, JL1
Sánchez-Harguindey, L1
Macaya, C1
Aronow, WS1
Tran, H1
Anand, SS1
Koopman, MM1
Büller, HR1
Lorenzen, ND1
Eldrup, N1
Laustsen, J1
Mocini, D1
Uguccioni, M1
Galli, C1
Bianchi, C1
Bartoli, S1
Puce, E1
Palombi, M1
Thau, A1
Pozzar, F1
Pau, F1
Lindblad, B1
Wakefield, TW1
Stanley, TJ1
Bergqvist, D1
Nichol, BJ1
Greenfield, LJ1
Stanley, JC1
Bergentz, SE1
Bajnok, L1
Kozlovszky, B1
Varga, J1
Antalffy, J1
Olvasztó, S1
Fülöp, T1
Edmondson, RA1
Cohen, AT1
Das, SK1
Wagner, MB1
Kakkar, VV1
Schueppert, MT1
Kresowik, TF2
Corry, DC1
Jacobovicz, C1
Mohan, CR1
Slaymaker, E1
Hoballah, JJ2
Sharp, WJ2
Grover-McKay, M1
Corson, JD2
Massie, MT1
Rohrer, MJ1
Leppo, JA1
Cutler, BS1
Rossi, E1
Citterio, F1
Vescio, MF1
Pennestri, F1
Lombardo, A1
Loperfido, F1
Maseri, A1
Safi, AM1
Pillai, N1
Rachko, M1
Chaudhry, K1
Stein, RA1
Matsagas, MI1
Geroulakos, G1
Mikhailidis, DP1
Beller, GA1
Saniabadi, AR1
Fisher, TC1
Lau, CS1
Bridges, A1
Taylor, J1
Belch, J1
Forbes, CD1
Koch, M1
Viaud, JF1
Cittone, S1
Douard, H1
Oysel, N1
Broustet, JP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Prolonged Dual Antiplatelet Therapy With Clopidogrel Plus Acetylsalicylic Acid (ASA) After Percutaneous Lower Extremity Revascularization in Patients With Peripheral Arterial Disease[NCT02798913]Phase 3300 participants (Anticipated)Interventional2016-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for dipyridamole and Peripheral Vascular Diseases

ArticleYear
Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery.
    The Cochrane database of systematic reviews, 2015, Feb-19, Issue:2

    Topics: Anastomosis, Surgical; Anticoagulants; Arteriosclerosis; Aspirin; Dipyridamole; Graft Occlusion, Vas

2015
Aspirin for the prevention of cardiovascular events in patients with peripheral artery disease: a meta-analysis of randomized trials.
    JAMA, 2009, May-13, Volume: 301, Issue:18

    Topics: Aspirin; Cardiovascular Diseases; Dipyridamole; Humans; Peripheral Vascular Diseases; Platelet Aggre

2009
Antiplatelet therapy in peripheral arterial disease.
    Current drug targets. Cardiovascular & haematological disorders, 2004, Volume: 4, Issue:3

    Topics: Arterial Occlusive Diseases; Aspirin; Clopidogrel; Dipyridamole; Humans; Peripheral Vascular Disease

2004
Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease.
    JAMA, 2004, Oct-20, Volume: 292, Issue:15

    Topics: Administration, Oral; Angina Pectoris; Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopido

2004
Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment.
    The Cochrane database of systematic reviews, 2005, Jan-25, Issue:1

    Topics: Angioplasty, Balloon; Anticoagulants; Aspirin; Dipyridamole; Humans; Peripheral Vascular Diseases; P

2005
[Antiplatelet and anticoagulant treatment after percutaneous transluminal angioplasty for peripheral arteriosclerosis. Survey of a Cochrane review].
    Ugeskrift for laeger, 2007, Sep-24, Volume: 169, Issue:39

    Topics: Angioplasty, Balloon; Anticoagulants; Arteriosclerosis; Aspirin; Dipyridamole; Evidence-Based Medici

2007
The role of platelets in peripheral arterial disease: therapeutic implications.
    Annals of vascular surgery, 2002, Volume: 16, Issue:2

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Peripheral Vascular Diseases;

2002

Trials

2 trials available for dipyridamole and Peripheral Vascular Diseases

ArticleYear
Dipyridamole echocardiography and 99mTc-MIBI spect dipyridamole scintigraphy for cardiac evaluation prior to peripheral vascular surgery.
    Minerva cardioangiologica, 1995, Volume: 43, Issue:5

    Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Coronary Disease; Dipyridamole; Echocardiograph

1995
Low-molecular weight heparin versus aspirin and dipyridamole after femoropopliteal bypass grafting.
    Lancet (London, England), 1994, Oct-01, Volume: 344, Issue:8927

    Topics: Adult; Aged; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Femoral Artery; Graft Occlusi

1994

Other Studies

14 other studies available for dipyridamole and Peripheral Vascular Diseases

ArticleYear
Aspirin for prevention of stroke and cardiovascular events among patients with peripheral artery disease.
    JAMA, 2009, Sep-16, Volume: 302, Issue:11

    Topics: Aspirin; Cardiovascular Diseases; Dipyridamole; Humans; Peripheral Vascular Diseases; Platelet Aggre

2009
Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway.
    Cardiovascular research, 2010, Mar-01, Volume: 85, Issue:4

    Topics: Animals; Cell Division; Chronic Disease; Cyclic AMP-Dependent Protein Kinases; Dipyridamole; Dose-Re

2010
[Anticoagulation and antiaggregation in patients with peripheral arterial occlusive diseases].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:1

    Topics: Administration, Oral; Angioplasty, Balloon; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Bl

2003
Negative predictive value of dipyridamole vs. dobutamine stress echocardiography in the long-term follow-up of patients undergoing major vascular surgery.
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2004, Volume: 23, Issue:1

    Topics: Aged; Cardiotonic Agents; Dipyridamole; Dobutamine; Echocardiography, Stress; Female; Follow-Up Stud

2004
Pharmacological prophylaxis against postoperative graft occlusion after peripheral vascular surgery: a world-wide survey.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1995, Volume: 9, Issue:3

    Topics: Anticoagulants; Aspirin; Data Collection; Dipyridamole; Drug Utilization; Graft Occlusion, Vascular;

1995
Technetium-99m sestamibi scintigraphy for the assessment of lower extremity ischaemia in peripheral arterial disease.
    European journal of nuclear medicine, 1994, Volume: 21, Issue:12

    Topics: Dipyridamole; Female; Heart; Humans; Ischemia; Leg; Male; Middle Aged; Peripheral Vascular Diseases;

1994
Selection of patients for cardiac evaluation before peripheral vascular operations.
    Journal of vascular surgery, 1996, Volume: 23, Issue:5

    Topics: Aged; Coronary Angiography; Coronary Disease; Dipyridamole; Elective Surgical Procedures; Evaluation

1996
Cardiac screening tests prior to lower extremity revascularization: routine versus selective application.
    Seminars in vascular surgery, 1997, Volume: 10, Issue:1

    Topics: Coronary Disease; Dipyridamole; Heart Function Tests; Humans; Inguinal Canal; Ischemia; Leg; Periphe

1997
Is coronary angiography necessary for vascular surgery patients who have positive results of dipyridamole thallium scans?
    Journal of vascular surgery, 1997, Volume: 25, Issue:6

    Topics: Case-Control Studies; Coronary Angiography; Coronary Disease; Dipyridamole; Female; Heart; Humans; M

1997
Risk stratification of patients undergoing peripheral vascular revascularization by combined resting and dipyridamole echocardiography.
    The American journal of cardiology, 1998, Aug-01, Volume: 82, Issue:3

    Topics: Aged; Aged, 80 and over; Dipyridamole; Echocardiography; Exercise Test; Female; Follow-Up Studies; H

1998
Dipyridamole-induced ST-segment elevation indicative of transmural myocardial ischemia--a case report.
    Angiology, 2001, Volume: 52, Issue:8

    Topics: Coronary Angiography; Dipyridamole; Electrocardiography; Follow-Up Studies; Humans; Male; Middle Age

2001
Are you ever too old to be risk stratified?
    Journal of the American College of Cardiology, 1992, Volume: 19, Issue:7

    Topics: Age Factors; Aged; Coronary Disease; Dipyridamole; Exercise Test; Heart; Humans; Middle Aged; Periph

1992
Dipyridamole increases human red blood cell deformability.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:6

    Topics: Adult; Aged; Dipyridamole; Erythrocyte Deformability; Female; Humans; Kidney Failure, Chronic; Male;

1992
[Which coronary investigation should be performed in patients with peripheral arterial diseases?].
    Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:11 Suppl

    Topics: Coronary Angiography; Coronary Disease; Decision Trees; Dipyridamole; Electrocardiography; Exercise

1991