dipyridamole has been researched along with Parkinson Disease in 2 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dipyridamole (DIP) was tested for its ability to induce dopaminergic (DA) phenotype in cultures from epidermal growth factor-derived mesencephalic precursor cells." | 1.31 | Dipyridamole-induced increase in production of rat dopaminergic neurons from mesencephalic precursors. ( Caruncho, HJ; Guerra, MJ; Labandeira-García, JL; Rodríguez-Pallares, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodríguez-Pallares, J | 1 |
| Caruncho, HJ | 1 |
| Guerra, MJ | 1 |
| Labandeira-García, JL | 1 |
| Danta, G | 1 |
2 other studies available for dipyridamole and Parkinson Disease
| Article | Year |
|---|---|
Dipyridamole-induced increase in production of rat dopaminergic neurons from mesencephalic precursors.
Topics: Animals; Brain Tissue Transplantation; Cell Differentiation; Cell Size; Cells, Cultured; Dipyridamol | 2002 |
Second phase platelet aggregation induced by adenosine diphosphate in patients with cerebral vascular disease and in control subjects.
Topics: Adenine Nucleotides; Adult; Aged; Blood Platelets; Bronchitis; Carpal Tunnel Syndrome; Cerebrovascul | 1970 |