dipyridamole has been researched along with Pain in 20 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 68-year-old woman reported acute severe pain in both lower limbs during a dipyridamole sestamibi myocardial perfusion scan." | 8.80 | Reversible severe lower limb pain during a dipyridamole sestamibi myocardial perfusion study: a case report. ( Szeto, E; Wong, DC, 1998) |
| "Adenosine analogs produce antinociception in normal animals and reduce allodynia and hyperalgesia following inflammation and nerve injury following spinal injection, yet none have been tested for clinical safety." | 5.30 | Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain. ( Eisenach, JC; Lavand'homme, PM, 1999) |
| "A 68-year-old woman reported acute severe pain in both lower limbs during a dipyridamole sestamibi myocardial perfusion scan." | 4.80 | Reversible severe lower limb pain during a dipyridamole sestamibi myocardial perfusion study: a case report. ( Szeto, E; Wong, DC, 1998) |
| "Prostatic acid phosphatase (PAP) and ecto-5'-nucleotidase (NT5E, CD73) produce extracellular adenosine from the nucleotide AMP in spinal nociceptive (pain-sensing) circuits; however, it is currently unknown if these are the main ectonucleotidases that generate adenosine or how rapidly they generate adenosine." | 3.77 | PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine. ( Guillot, TS; Sowa, NA; Street, SE; Taylor-Blake, B; Vihko, P; Walsh, PL; Wightman, RM; Zylka, MJ, 2011) |
| "Patients with chest pain syndromes and normal coronary angiograms were studied with a new set of methods that included thermodilution coronary sinus blood flow and coronary dye dilution curves with special computer analysis, oxygen and lactate determinations, thallium scannings, atrial pacing and dipyridamole tests." | 3.67 | Evidence of myocardial ischaemia in patients with chest pain syndromes and normal coronary angiograms. ( Virtanen, KS, 1985) |
| "The relationship of coronary anatomy to right ventricular (RV) appearance on serial thallium-201 myocardial imaging (TI) following dipyridamole (DP)-induced coronary vasodilation was examined in 71 consecutive patients undergoing coronary angiography for the evaluation of chest pain." | 3.66 | Initial and delayed right ventricular thallium-201 rest-imaging following dipyridamole-induced coronary vasodilation: relationship to right coronary artery pathoanatomy. ( Boucher, CA; Brown, KA; Okada, RD; Pohost, G; Strauss, HW, 1982) |
| "On the basis of an examination of 412 patients with myocardial infarction the efficacy of a long-term employment (for 3--4 days) of a neuroleptic Droperidol and a vasodilator Curantyl was examined." | 3.65 | [Experience with combined use of neurolepsy and vasodilator substances in the treatment of patients with acute myocardial infarct]. ( Aleksandrova, LA; Avdiushko, BR; Gvatua, NA; Kravtsov, VL; Strokach, NT, 1976) |
| "Adenosine analogs produce antinociception in normal animals and reduce allodynia and hyperalgesia following inflammation and nerve injury following spinal injection, yet none have been tested for clinical safety." | 1.30 | Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain. ( Eisenach, JC; Lavand'homme, PM, 1999) |
| "Dipyridamole was given to 15 patients with chronic pain in an open uncontrolled investigation." | 1.28 | An open label trial of the possible analgesic effects of dipyridamole. ( Hamilton, JT; Merskey, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (75.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Street, SE | 1 |
| Walsh, PL | 1 |
| Sowa, NA | 1 |
| Taylor-Blake, B | 1 |
| Guillot, TS | 1 |
| Vihko, P | 1 |
| Wightman, RM | 1 |
| Zylka, MJ | 1 |
| Schmoliner, R | 1 |
| Dudczak, R | 1 |
| Kronik, G | 1 |
| Mösslacher, H | 1 |
| Zangeneh, M | 1 |
| Pollak, C | 1 |
| Schurz, B | 1 |
| Schoberwalter, A | 1 |
| Brown, BG | 1 |
| Josephson, MA | 1 |
| Petersen, RB | 1 |
| Pierce, CD | 1 |
| Wong, M | 1 |
| Hecht, HS | 1 |
| Bolson, E | 1 |
| Dodge, HT | 1 |
| Brown, KA | 1 |
| Boucher, CA | 1 |
| Okada, RD | 1 |
| Strauss, HW | 1 |
| Pohost, G | 1 |
| Feldman, RL | 1 |
| Nichols, WW | 1 |
| Pepine, CJ | 1 |
| Conti, CR | 1 |
| Olatidoye, AG | 1 |
| Baltazar, RF | 1 |
| Wong, DC | 1 |
| Szeto, E | 1 |
| Lavand'homme, PM | 1 |
| Eisenach, JC | 1 |
| Rosen, SD | 1 |
| Callis, M | 1 |
| Alkjaersig, N | 1 |
| Fletcher, A | 1 |
| Joist, H | 1 |
| Chaplin, H | 1 |
| Gvatua, NA | 1 |
| Avdiushko, BR | 1 |
| Aleksandrova, LA | 1 |
| Strokach, NT | 1 |
| Kravtsov, VL | 1 |
| Merskey, H | 1 |
| Hamilton, JT | 1 |
| Picano, E | 1 |
| Distante, A | 1 |
| Masini, M | 1 |
| Moscarelli, E | 1 |
| Lattanzi, F | 1 |
| Lombardi, M | 1 |
| Morales, MA | 1 |
| L'Abbate, A | 1 |
| Virtanen, KS | 1 |
| Mackay, A | 1 |
| de Bono, DP | 1 |
| Popescu, P | 1 |
| Gherasim, L | 1 |
| Howenstine, JA | 1 |
| Slaton, P | 1 |
| Spitalny, A | 1 |
| Lee, J | 1 |
| Frick, MH | 1 |
| Somer, T | 1 |
| Igloe, MC | 1 |
1 review available for dipyridamole and Pain
| Article | Year |
|---|---|
Reversible severe lower limb pain during a dipyridamole sestamibi myocardial perfusion study: a case report.
Topics: Aged; Dipyridamole; Female; Heart; Humans; Leg; Pain; Radiopharmaceuticals; Technetium Tc 99m Sestam | 1998 |
2 trials available for dipyridamole and Pain
| Article | Year |
|---|---|
Assessment of the effect of long-term dipyridamole in angina pectoris by atrial pacing and physical exercise.
Topics: Adult; Angina Pectoris; Blood Pressure; Cardiac Catheterization; Clinical Trials as Topic; Collatera | 1971 |
Treatment of angina pectoris with dipyridamole: a double-blind study.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Dipyridamole; Female; Humans; Locomotion; Male; Mid | 1970 |
17 other studies available for dipyridamole and Pain
| Article | Year |
|---|---|
PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine.
Topics: 5'-Nucleotidase; Acid Phosphatase; Adenosine; Adenosine Monophosphate; Animals; Dipyridamole; Gangli | 2011 |
Impact of thallium-201 imaging on clinical assessment and management of patients with chest pain.
Topics: Angiography; Coronary Disease; Dipyridamole; Female; Heart; Humans; Male; Pain; Probability; Radiois | 1984 |
Intravenous dipyridamole combined with isometric handgrip for near maximal acute increase in coronary flow in patients with coronary artery disease.
Topics: Acute Disease; Constriction, Pathologic; Coronary Angiography; Coronary Circulation; Coronary Diseas | 1981 |
Initial and delayed right ventricular thallium-201 rest-imaging following dipyridamole-induced coronary vasodilation: relationship to right coronary artery pathoanatomy.
Topics: Adult; Aged; Arterial Occlusive Diseases; Coronary Angiography; Coronary Disease; Coronary Vessels; | 1982 |
Acute effect of intravenous dipyridamole on regional coronary hemodynamics and metabolism.
Topics: Adult; Aged; Coronary Angiography; Coronary Circulation; Coronary Vessels; Dipyridamole; Electrocard | 1981 |
Dipyridamole-thallium stress testing: a local community hospital experience.
Topics: Aged; Aged, 80 and over; Clinical Protocols; Coronary Disease; Dipyridamole; Dyspnea; Electrocardiog | 1993 |
Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain.
Topics: Adenosine; Analgesics, Opioid; Animals; Deoxyadenosines; Dipyridamole; Drug Synergism; Injections, S | 1999 |
The pathophysiology of cardiac syndrome X--a tale of paradigm shifts.
Topics: 3-Iodobenzylguanidine; Adenosine; Coronary Disease; Dipyridamole; Heart Rate; Humans; Microvascular | 2001 |
[Ischemic lesions in polycythaemia vera (author's transl)].
Topics: Aspirin; Dipyridamole; Female; Foot; Humans; Ischemia; Male; Middle Aged; Pain; Polycythemia Vera; S | 1977 |
Hemostatic alterations accompanying sickle cell pain crises.
Topics: Acute Disease; Adult; Anemia, Sickle Cell; Aspirin; Blood Cell Count; Blood Platelets; Blood Transfu | 1976 |
[Experience with combined use of neurolepsy and vasodilator substances in the treatment of patients with acute myocardial infarct].
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Dipyridamole; Drop | 1976 |
An open label trial of the possible analgesic effects of dipyridamole.
Topics: Adult; Analgesics; Chronic Disease; Dipyridamole; Female; Follow-Up Studies; Humans; Male; Middle Ag | 1989 |
Echocardiographic documentation of myocardial ischemia in presence of angina pectoris without ST-T changes.
Topics: Adult; Angina Pectoris; Coronary Circulation; Coronary Disease; Dipyridamole; Echocardiography; Elec | 1986 |
Evidence of myocardial ischaemia in patients with chest pain syndromes and normal coronary angiograms.
Topics: Adult; Aged; Angiography; Cardiac Pacing, Artificial; Catheterization; Coronary Angiography; Coronar | 1985 |
Valvar aortic stenosis in adults: an update.
Topics: Adult; Anticoagulants; Aortic Valve Stenosis; Aspirin; Calcinosis; Dipyridamole; Echocardiography; E | 1986 |
[Current problems in diagnosis and treatment of angina pectoris].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angiography; Anticoagulants; Benzofurans; Coronary Ang | 1972 |
Flank pain and hematuria in a young man with renal artery arteriosclerosis: remission of symptoms during administration of dipyridamole.
Topics: Adult; Angiography; Arteriosclerosis; Dipyridamole; Hematuria; Hemorrhage; Humans; Ischemia; Kidney; | 1974 |