dipyridamole has been researched along with Osteosarcoma in 4 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test a novel strategy for overcoming intrinsic resistance to methotrexate (MTX) in osteosarcoma (OS) due to nucleoside and nucleobase salvage (NS)." | 7.71 | Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs. ( Cole, PD; Kamen, BA; Smith, AK, 2002) |
| "To test a novel strategy for overcoming intrinsic resistance to methotrexate (MTX) in osteosarcoma (OS) due to nucleoside and nucleobase salvage (NS)." | 3.71 | Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs. ( Cole, PD; Kamen, BA; Smith, AK, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vlachodimou, A | 1 |
| IJzerman, AP | 1 |
| Heitman, LH | 1 |
| Cole, PD | 1 |
| Smith, AK | 1 |
| Kamen, BA | 1 |
| Goda, AE | 1 |
| Yoshida, T | 1 |
| Horinaka, M | 1 |
| Yasuda, T | 1 |
| Shiraishi, T | 1 |
| Wakada, M | 1 |
| Sakai, T | 1 |
| Nelson, JA | 1 |
| Drake, S | 1 |
4 other studies available for dipyridamole and Osteosarcoma
| Article | Year |
|---|---|
Label-free detection of transporter activity via GPCR signalling in living cells: A case for SLC29A1, the equilibrative nucleoside transporter 1.
Topics: Cell Line, Tumor; Equilibrative Nucleoside Transporter 1; Humans; Ligands; Membrane Transport Protei | 2019 |
Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Bone Neoplasms; Cattle; Culture Medi | 2002 |
Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole.
Topics: Apoptosis; Blotting, Northern; Bone Neoplasms; Colonic Neoplasms; Cyclic AMP-Dependent Protein Kinas | 2008 |
Potentiation of methotrexate toxicity by dipyridamole.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Survival; Cricetinae; Crice | 1984 |