Page last updated: 2024-10-26

dipyridamole and Osteoarthritis

dipyridamole has been researched along with Osteoarthritis in 3 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
" The most frequently reported adverse event during the study was headache (52% in CRx-102 vs 15% in the placebo group)."2.73Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis. ( Borisy, AA; Fjeld, E; Kvien, TK; Lessem, J; Mikkelsen, K; Nichols, M; Palm, Ø; Prøven, A; Slatkowsky-Christensen, B; Zhang, Y, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haugen, IK1
Slatkowsky-Christensen, B2
Lessem, J2
Kvien, TK2
Fjeld, E1
Nichols, M1
Zhang, Y1
Prøven, A1
Mikkelsen, K1
Palm, Ø1
Borisy, AA1
Alakhras, M1
Baldari, D1
El-Sherif, N1
Turitto, G1

Trials

2 trials available for dipyridamole and Osteoarthritis

ArticleYear
The responsiveness of joint counts, patient-reported measures and proposed composite scores in hand osteoarthritis: analyses from a placebo-controlled trial.
    Annals of the rheumatic diseases, 2010, Volume: 69, Issue:8

    Topics: Adult; Aged; Antirheumatic Agents; Dipyridamole; Drug Combinations; Female; Hand Joints; Humans; Mal

2010
Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis.
    Annals of the rheumatic diseases, 2008, Volume: 67, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents; Dipyridamole; Double-Blind Method; Drug Combinations; Female;

2008

Other Studies

1 other study available for dipyridamole and Osteoarthritis

ArticleYear
Location and clinical implications of high-degree atrioventricular block during dipyridamole infusion: a case report.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2002, Volume: 7, Issue:2

    Topics: Aged; Dipyridamole; Electrocardiography; Female; Heart Block; Humans; Hypertension; Osteoarthritis;

2002