Page last updated: 2024-10-26

dipyridamole and Necrosis

dipyridamole has been researched along with Necrosis in 19 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Ischemic necrosis has been most dreaded complication of flap reconstruction."1.56Effect of dipyridamole on random pattern skin flap viability in rats. ( Uslu, AB, 2020)
"Necrosis was minimal, averaging only 2."1.27Impaired function of salvaged myocardium: two-dimensional echocardiographic quantification of regional wall thickening in the open-chest dog. ( Becker, LC; Blumenthal, DS; Bulkley, BH; Hutchins, GM; Weisfeldt, ML; Weiss, JL, 1983)
"Dipyridamole was effective from 1 hr before through 6 hrs after the oral administration of CCl4."1.26Decrease of carbon tetrachloride liver toxicity in rats given dipyridamole. ( Kast, A; Nishikawa, J; Yabe, T, 1982)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199015 (78.95)18.7374
1990's3 (15.79)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Uslu, AB1
Blumenthal, DS1
Becker, LC1
Bulkley, BH1
Hutchins, GM1
Weisfeldt, ML1
Weiss, JL1
Gichka, SG1
Giannini, SD1
Sanchis, FS1
Guerra, JL1
Merusse, JL1
Kast, A1
Nishikawa, J1
Yabe, T1
Alksne, JF1
Branson, PJ1
Mosca, SM1
Gelpi, RJ1
Cingolani, HE1
Requena, L1
Fariña, C1
Barat, A1
Weisse, AB1
Regan, TJ1
Lanovaia, NI1
Kraikitpanitch, S1
Haygood, CC1
Baxter, DJ1
Yunice, AA1
Lindeman, RD1
Cifaldi, S1
Viglietto, A1
Marone, G1
Azzinnari, G1
Colantuoni, A1
Hornsey, S1
Myers, R1
Jenkinson, T1
Vassanelli, C1
Menegatti, G1
Nidasio, GP1
Franceschini, L1
Cocco, C1
Rizzotti, P1
Markiewicz, K1
Cholewa, M1
Jazdzewski, B1
Budzyła, J1
Górski, L1
Gawor, Z1
Friedman, A1
Kincaid-Smith, P1
Hayhurst, JW1
O'Brien, BM1
Ishida, H1
Baxter, TJ1
Haft, JI1
Gershengorn, K1
Kranz, PD1
Oestreicher, R1
Becker, RM1
Shizgal, HM1
Dobell, AR1

Other Studies

19 other studies available for dipyridamole and Necrosis

ArticleYear
Effect of dipyridamole on random pattern skin flap viability in rats.
    Journal of plastic surgery and hand surgery, 2020, Volume: 54, Issue:4

    Topics: Animals; Dipyridamole; Graft Survival; Male; Necrosis; Postoperative Complications; Random Allocatio

2020
Impaired function of salvaged myocardium: two-dimensional echocardiographic quantification of regional wall thickening in the open-chest dog.
    Circulation, 1983, Volume: 67, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Disease; Dipyridamole; Dogs; Echocardiography; Epoprostenol;

1983
[Morphological criteria of the effectiveness of nitroglycerin, dipyridamole and propranolol hydrochloride in an experimental metabolic lesion of the myocardium].
    Vrachebnoe delo, 1984, Issue:7

    Topics: Animals; Cardiomyopathies; Dipyridamole; Drug Evaluation, Preclinical; Histocytochemistry; Male; Myo

1984
[Cardiovascular lesions induced in rats by vitamin D. Possible protective effect of sulfinpyrazone].
    Arquivos brasileiros de cardiologia, 1983, Volume: 41, Issue:3

    Topics: Animals; Arteries; Cardiovascular Diseases; Dipyridamole; Male; Myocardium; Necrosis; Oxyphenbutazon

1983
Decrease of carbon tetrachloride liver toxicity in rats given dipyridamole.
    Experimental pathology, 1982, Volume: 21, Issue:2

    Topics: 1-Propanol; Animals; Body Temperature; Carbon Tetrachloride; Dipyridamole; Dose-Response Relationshi

1982
Prevention of arterial injury reaction to adventitial blood with intravenous persantine.
    Angiology, 1982, Volume: 33, Issue:12

    Topics: Animals; Arteries; Blood Coagulation; Cell Division; Dipyridamole; Injections, Intravenous; Necrosis

1982
Adenosine and dipyridamole mimic the effects of ischemic preconditioning.
    Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:10

    Topics: Adaptation, Physiological; Adenosine; Animals; Blood Pressure; Dipyridamole; Myocardial Ischemia; My

1994
Degos disease in a patient with acquired immunodeficiency syndrome.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:5 Pt 2

    Topics: Acquired Immunodeficiency Syndrome; Atrophy; Cicatrix; Dipyridamole; Erythema; Homosexuality, Male;

1998
A comparison of four potential agents for reducing necrosis after prolonged coronary occlusion.
    Journal of clinical pharmacology, 1978, Volume: 18, Issue:4

    Topics: Animals; Cardiac Catheterization; Coronary Disease; Dipyridamole; Dogs; Dose-Response Relationship,

1978
[Prevention of the myocardial damaging effect of isadrin by curantil].
    Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 86, Issue:11

    Topics: Animals; Coronary Disease; Dipyridamole; Electrocardiography; Female; Isoproterenol; Male; Myocardia

1978
Effects of acetylsalicylic acid, dipyridamole, and hydrocortisone on epinephrine-induced myocardial injury in dogs.
    American heart journal, 1976, Volume: 92, Issue:5

    Topics: Acute Disease; Animals; Aspartate Aminotransferases; Aspirin; Calcium; Calcium Chloride; Cardiomyopa

1976
[Hyperbaric oxygen and coronary dilator agents in experimental necrosis of the myocardium in rats].
    Bollettino della Societa italiana di biologia sperimentale, 1975, Apr-15, Volume: 51, Issue:7

    Topics: Animals; Dipyridamole; Hyperbaric Oxygenation; Myocardial Infarction; Necrosis; Papaverine; Rats; Va

1975
The reduction of radiation damage to the spinal cord by post-irradiation administration of vasoactive drugs.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:6

    Topics: Animals; Deferoxamine; Dipyridamole; Male; Necrosis; Radiation Injuries, Experimental; Rats; Reperfu

1990
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
    Clinical biochemistry, 1987, Volume: 20, Issue:6

    Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; I

1987
[Attempts at limiting necrotic areas in acute myocardial infarction by intravenous infusion of dipyridamole].
    Polskie Archiwum Medycyny Wewnetrznej, 1987, Volume: 77, Issue:5

    Topics: Adult; Aged; Creatine Kinase; Dipyridamole; Female; Humans; Infusions, Intravenous; Isoenzymes; Male

1987
Arteritis with impaired renal function.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0

    Topics: Adult; Aged; Anticoagulants; Azathioprine; Biopsy; Cyclophosphamide; Dipyridamole; Drug Therapy, Com

1973
Experimental digital replantation after prolonged cooling.
    The Hand, 1974, Volume: 6, Issue:2

    Topics: Animals; Arteries; Aspirin; Autopsy; Cold Temperature; Dipyridamole; Fingers; Graft Rejection; Haplo

1974
Protection against epinephrine-induced myocardial necrosis by drugs that inhibit platelet aggregation.
    The American journal of cardiology, 1972, Volume: 30, Issue:8

    Topics: Animals; Arteriosclerosis; Aspirin; Catecholamines; Dipyridamole; Dogs; Epinephrine; Heart; Myocardi

1972
Distribution of coronary blood flow during cardiopulmonary bypass in pigs.
    The Annals of thoracic surgery, 1973, Volume: 16, Issue:3

    Topics: Animals; Chromium Isotopes; Coronary Circulation; Dipyridamole; Extracorporeal Circulation; Heart Ve

1973