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dipyridamole and Necrobiosis Lipoidica

dipyridamole has been researched along with Necrobiosis Lipoidica in 9 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Necrobiosis Lipoidica: A degenerative disease of the dermal connective tissue characterized by the development of erythematous papules or nodules in the pretibial area. The papules form plaques covered with telangiectatic vessels. More than half of the affected patients have diabetes.

Research Excerpts

ExcerptRelevanceReference
"Fourteen patients with a clinical and histological diagnosis of necrobiosis lipoidica were treated in a double-blind control study with either an aspirin dipyridamole combination or a matching placebo for an 8-week period."9.05A randomized double blind comparison of an aspirin dipyridamole combination versus a placebo in the treatment of necrobiosis lipoidica. ( Finlay, AY; Marks, R; Statham, B, 1981)
"Fourteen patients with a clinical and histological diagnosis of necrobiosis lipoidica were treated in a double-blind control study with either an aspirin dipyridamole combination or a matching placebo for an 8-week period."5.05A randomized double blind comparison of an aspirin dipyridamole combination versus a placebo in the treatment of necrobiosis lipoidica. ( Finlay, AY; Marks, R; Statham, B, 1981)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiquan, S1
Khalaf, AT1
Jinquan, T1
Xiaoming, L1
Statham, B1
Finlay, AY2
Marks, R2
Kakinuma, H1
Fuzisawa, S1
Usami, Y1
Statham, BN1
Eldor, A1
Diaz, EG1
Naparstek, E1
Császár, A1
Daróczy, J1
Szénási, P1
Anda, L1
Tóth, L1
Hosszúfalusi, N1
Karádi, I1
Kalabay, L1
Romics, L1
Quimby, SR1
Muller, SA1
Schroeter, AL1
Fuster, V1
Kazmier, FJ1
Heng, MC1
Song, MK1
Heng, MK1

Reviews

1 review available for dipyridamole and Necrobiosis Lipoidica

ArticleYear
[Necrobiosis lipoidica without diabetes mellitus (diagnostic and therapeutic possibilities)].
    Orvosi hetilap, 1989, Oct-01, Volume: 130, Issue:40

    Topics: Aspirin; Basement Membrane; Capillaries; Diabetic Angiopathies; Diagnosis, Differential; Dipyridamol

1989

Trials

2 trials available for dipyridamole and Necrobiosis Lipoidica

ArticleYear
A randomized double blind comparison of an aspirin dipyridamole combination versus a placebo in the treatment of necrobiosis lipoidica.
    Acta dermato-venereologica, 1981, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Drug Combin

1981
Aspirin and dipyridamole ineffective in treatment of necrobiosis lipoidica.
    The New England journal of medicine, 1980, 12-11, Volume: 303, Issue:24

    Topics: Aspirin; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Hum

1980

Other Studies

6 other studies available for dipyridamole and Necrobiosis Lipoidica

ArticleYear
Necrobiosis lipoidica: a case with histopathological findings revealed asteroid bodies and was successfully treated with dipyridamole plus intralesional triamcinolone.
    The Journal of dermatological treatment, 2008, Volume: 19, Issue:1

    Topics: Dipyridamole; Drug Therapy, Combination; Female; Giant Cells; Humans; Immunosuppressive Agents; Midd

2008
[A case of necrobiosis lipoidica diabeticorum (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1981, Volume: 91, Issue:8

    Topics: Adult; Aspirin; Dipyridamole; Humans; Male; Necrobiosis Lipoidica

1981
Treatment of diabetic necrobiosis with aspirin and dipyridamole.
    The New England journal of medicine, 1978, May-04, Volume: 298, Issue:18

    Topics: Adult; Aspirin; Diabetes Mellitus, Type 1; Dipyridamole; Female; Humans; Necrobiosis Lipoidica

1978
Treatment of diabetic necrobiosis with aspirin or dipyridamole.
    The New England journal of medicine, 1978, 12-14, Volume: 299, Issue:24

    Topics: Adolescent; Adult; Animals; Aspirin; Diabetes Complications; Diabetes Mellitus, Type 1; Dipyridamole

1978
Necrobiosis lipoidica diabeticorum: platelet survival and response to platelet inhibitors.
    Cutis, 1989, Volume: 43, Issue:3

    Topics: Adult; Aspirin; Blood Platelets; Cell Survival; Dipyridamole; Drug Administration Schedule; Drug The

1989
Healing of necrobiotic ulcers with antiplatelet therapy. Correlation with plasma thromboxane levels.
    International journal of dermatology, 1989, Volume: 28, Issue:3

    Topics: Adult; Aged; Aspirin; Blood Platelets; Dipyridamole; Drug Therapy, Combination; Humans; Leg Ulcer; M

1989