dipyridamole has been researched along with Melanoma in 7 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Enhancement of the anti-proliferative effect of human interferon (HuIFN) preparations (alpha, beta and gamma) by dipyridamole was detected in a human malignant melanoma cell line, MM-ICB, which we originally established." | 7.68 | Enhancement of an anti-tumor effect of interferon by dipyridamole in established human malignant melanoma cell lines. ( Hayata, I; Kojima, T; Sugano, I; Suzuki, N, 1990) |
| "The combined effects of adriamycin (ADM) and dipyridamole (DP) on lung metastasis of B16 melanoma cells in mice were investigated." | 7.68 | Combined treatment of adriamycin and dipyridamole inhibits lung metastasis of B16 melanoma cells in mice. ( Emi, Y; Kohnoe, S; Maehara, Y; Sakaguchi, Y; Sugimachi, K, 1990) |
| "The combined effects of adriamycin (ADM) and dipyridamole (DP) on lung metastasis of B16 melanoma cells in mice were investigated." | 3.68 | Combined treatment of adriamycin and dipyridamole inhibits lung metastasis of B16 melanoma cells in mice. ( Emi, Y; Kohnoe, S; Maehara, Y; Sakaguchi, Y; Sugimachi, K, 1990) |
| "In the search for cytokines whose antiproliferative action could be enhanced by combination with dipyridamole, 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrim idine, the combination of tumor necrosis factor-alpha (TNF-alpha) with this agent was evaluated in various human tumor cell lines." | 1.29 | Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines. ( Kojima, T; Sekiya, S; Sugano, I; Suzuki, N; Takakubo, Y; Yamamori, H, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bando, H | 1 |
| Yamashita, T | 1 |
| Tsubura, E | 1 |
| Suzuki, N | 2 |
| Sekiya, S | 1 |
| Sugano, I | 2 |
| Kojima, T | 2 |
| Yamamori, H | 1 |
| Takakubo, Y | 1 |
| Dollinger, MR | 1 |
| Krakoff, IH | 1 |
| Hayata, I | 1 |
| Sakaguchi, Y | 1 |
| Emi, Y | 1 |
| Maehara, Y | 1 |
| Kohnoe, S | 1 |
| Sugimachi, K | 1 |
| Rhodes, EL | 1 |
| Misch, KJ | 1 |
| Edwards, JM | 1 |
| Jarrett, PE | 1 |
| Chan, TC | 1 |
| Young, B | 1 |
| King, ME | 1 |
| Taetle, R | 1 |
| Howell, SB | 1 |
7 other studies available for dipyridamole and Melanoma
| Article | Year |
|---|---|
Effects of antiplatelet agents on pulmonary metastases.
Topics: Adenosine Diphosphate; Animals; Depression, Chemical; Diltiazem; Dipyridamole; Dose-Response Relatio | 1984 |
Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines.
Topics: Amino Acids; Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carbon Rad | 1995 |
Hemolysis induced by 6-N-hydroxylaminopurine riboside, an adenosine analogue.
Topics: Adenosine; Adult; Bilirubin; Blood Cell Count; Breast Neoplasms; Dipyridamole; Erythrocytes; Female; | 1975 |
Enhancement of an anti-tumor effect of interferon by dipyridamole in established human malignant melanoma cell lines.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Female; Humans; Interfe | 1990 |
Combined treatment of adriamycin and dipyridamole inhibits lung metastasis of B16 melanoma cells in mice.
Topics: Animals; Dipyridamole; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Lun | 1990 |
Dipyridamole for treatment of melanoma.
Topics: Dipyridamole; Female; Humans; Male; Melanoma; Skin Neoplasms | 1985 |
Modulation of the activity of PALA by dipyridamole.
Topics: Animals; Aspartic Acid; Biological Transport; Cell Line; Colonic Neoplasms; Dipyridamole; Drug Inter | 1985 |