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dipyridamole and Lung Diseases, Obstructive

dipyridamole has been researched along with Lung Diseases, Obstructive in 17 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"Based on the hypothesis that blood platelets contribute to the pathogenesis of hypoxemic pulmonary hypertension in patients with chronic obstructive pulmonary disease (COPD), the effect of a prolonged treatment with dipyridamole, a platelet-inhibiting drug, on hypoxemic pulmonary hypertension was evaluated in a double-blind cross-over study."9.06Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease. ( Berrettini, M; Costantini, V; Nenci, GG; Parise, P; Todisco, T, 1988)
"We describe the occurrence of sudden severe bronchospasm and respiratory arrest following dipyridamole infusion in a patient with chronic obstructive pulmonary disease predominantly of the emphysematous type."7.67Severe bronchospasm followed by respiratory arrest during thallium-dipyridamole imaging. ( Cerino, M; Laverdiere, M; Lette, J; Prenovault, J; Tremblay, J, 1989)
"Based on the hypothesis that blood platelets contribute to the pathogenesis of hypoxemic pulmonary hypertension in patients with chronic obstructive pulmonary disease (COPD), the effect of a prolonged treatment with dipyridamole, a platelet-inhibiting drug, on hypoxemic pulmonary hypertension was evaluated in a double-blind cross-over study."5.06Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease. ( Berrettini, M; Costantini, V; Nenci, GG; Parise, P; Todisco, T, 1988)
"We prospectively screened patients referred for intravenous dipyridamole thallium testing and retrospectively reviewed a comparison group of patients who had undergone intravenous dipyridamole testing before our bronchospasm protocol."3.70Patients with stable chronic obstructive pulmonary disease can safely undergo intravenous dipyridamole thallium-201 imaging. ( Chaney, C; Nishiyama, H; Rauf, GC; Render, ML; Shaffer, J; Simbartl, L; Snow, E; Wexler, LF, 1998)
"We describe the occurrence of sudden severe bronchospasm and respiratory arrest following dipyridamole infusion in a patient with chronic obstructive pulmonary disease predominantly of the emphysematous type."3.67Severe bronchospasm followed by respiratory arrest during thallium-dipyridamole imaging. ( Cerino, M; Laverdiere, M; Lette, J; Prenovault, J; Tremblay, J, 1989)
" The test was found to be safe for patients over 70 yr old."1.28Safety of dipyridamole-thallium imaging in high risk patients with known or suspected coronary artery disease. ( Perper, EJ; Segall, GM, 1991)
"Hypertension was equally common in the two groups, but tended to be less well controlled in the epistaxis patients compared to the controls."1.28Drug-induced epistaxis? ( Shenoi, PM; Watson, MG, 1990)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's7 (41.18)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nenci, GG4
Berrettini, M3
Todisco, T3
Parise, P2
Costantini, V2
Grasselli, S1
Mantero, O2
Colli, S2
Maderna, P2
Lo Cicero, S1
Bertoli, L2
Tremoli, E2
Merlini, R1
Sirtori, CR1
Mirka, T1
Ottervanger, JP1
Haan, D1
Gans, SJ1
Hoorntje, JC1
Stricker, BH1
Leitha, T1
Gwechenberger, M1
Falger-Banyai, S1
Shaffer, J1
Simbartl, L1
Render, ML1
Snow, E1
Chaney, C1
Nishiyama, H1
Rauf, GC1
Wexler, LF1
Thurnheer, R1
Laube, I1
Kaufmann, PA1
Stumpe, KD1
Stammberger, U1
Bloch, KE1
Weder, W1
Russi, EW1
Vigdahl, RL1
Ferber, RH1
Parrish, SL1
Perper, EJ1
Segall, GM1
Watson, MG1
Shenoi, PM1
Lette, J1
Cerino, M1
Laverdiere, M1
Tremblay, J1
Prenovault, J1
Gensini, GF1
Rostagno, C1
Pezza, A1
Fanara, F1
Castellani, S1
Prisco, D1
Rogasi, PG1
Boddi, M1
Neri Serneri, GG1
Glbov, A1
Kis'ova, K1
Mastikova, M1
Metodiev, K1

Trials

2 trials available for dipyridamole and Lung Diseases, Obstructive

ArticleYear
Enhanced plasma beta-thromboglobulin in hypoxemia: effect of dipyridamole.
    The New England journal of medicine, 1981, Apr-23, Volume: 304, Issue:17

    Topics: Aged; Beta-Globulins; beta-Thromboglobulin; Clinical Trials as Topic; Dipyridamole; Female; Humans;

1981
Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease.
    Respiration; international review of thoracic diseases, 1988, Volume: 53, Issue:1

    Topics: Aged; Blood Pressure; Dipyridamole; Humans; Hypertension, Pulmonary; Hypoxia; Lung Diseases, Obstruc

1988

Other Studies

15 other studies available for dipyridamole and Lung Diseases, Obstructive

ArticleYear
Exhausted platelets in chronic obstructive pulmonary disease.
    Respiration; international review of thoracic diseases, 1983, Volume: 44, Issue:1

    Topics: Aged; beta-Thromboglobulin; Blood Platelets; Dipyridamole; Female; Humans; Lung Diseases, Obstructiv

1983
Platelets, hypoxemia and pulmonary hypertension.
    Advances in experimental medicine and biology, 1984, Volume: 164

    Topics: Blood Platelets; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Humans; Hypertension, Pulmon

1984
Pharmacological control of platelet-vessel wall interactions in patients with chronic obstructive airway disease.
    Giornale italiano di cardiologia, 1984, Volume: 14 Suppl 1

    Topics: Aspirin; Blood Platelets; Blood Vessels; Dipyridamole; Hematopoiesis; Humans; Lung Diseases, Obstruc

1984
Dipyridamole treatment in chronic obstructive airways disease: effect on platelet regeneration time.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:5

    Topics: Adult; Blood Gas Analysis; Blood Platelets; Dipyridamole; Humans; Lung Diseases, Obstructive; Male;

1982
Some deleterious effects of intravenous dipyridamole in the presence of chronic lung disease.
    Canadian journal of cardiovascular nursing = Journal canadien en soins infirmiers cardio-vasculaires, 1993, Volume: 4, Issue:1

    Topics: Bronchial Spasm; Coronary Disease; Dipyridamole; Humans; Lung Diseases, Obstructive

1993
[Bronchospasm, apnea and heart arrest following dipyridamole perfusion scintigraphy].
    Nederlands tijdschrift voor geneeskunde, 1993, Jan-16, Volume: 137, Issue:3

    Topics: Aged; Apnea; Bronchial Spasm; Dipyridamole; Heart Arrest; Humans; Lung Diseases, Obstructive; Male

1993
Does dyspnoea during dipyridamole cardiac stress testing indicate bronchospasm and is the pretest clinical history predictive of this side-effect?
    European journal of nuclear medicine, 1995, Volume: 22, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Bronchial Spasm; Dipyridamole; Dyspnea; Exercise Test; Female; Human

1995
Patients with stable chronic obstructive pulmonary disease can safely undergo intravenous dipyridamole thallium-201 imaging.
    American heart journal, 1998, Volume: 136, Issue:2

    Topics: Aged; Bronchial Spasm; Bronchodilator Agents; Dipyridamole; Exercise Test; Humans; Image Processing,

1998
Practicability and safety of dipyridamole cardiac imaging in patients with severe chronic obstructive pulmonary disease.
    European journal of nuclear medicine, 1999, Volume: 26, Issue:8

    Topics: Ammonia; Bronchoconstriction; Coronary Disease; Dipyridamole; Dyspnea; Female; Heart; Humans; Lung D

1999
Evaluation of antiinflammatory and antithrombotic drugs in pulmonary and arterial thrombosis.
    Thrombosis research, 1979, Volume: 16, Issue:1-2

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Anti-Inflammatory Agents; Arterial Occlusive Di

1979
Safety of dipyridamole-thallium imaging in high risk patients with known or suspected coronary artery disease.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:11

    Topics: Age Factors; Cardiac Catheterization; Chest Pain; Contraindications; Coronary Disease; Dipyridamole;

1991
Drug-induced epistaxis?
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Coronary Disease; Dipyr

1990
Severe bronchospasm followed by respiratory arrest during thallium-dipyridamole imaging.
    Chest, 1989, Volume: 95, Issue:6

    Topics: Aged; Albuterol; Bronchial Spasm; Dipyridamole; Humans; Lung Diseases, Obstructive; Lung Volume Meas

1989
Effects of dipyridamole infusion on local platelet aggregation and local formation of thromboxane A2 in patients with pulmonary hypertension.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 13

    Topics: beta-Thromboglobulin; Dipyridamole; Female; Humans; Hypertension, Pulmonary; Lung Diseases, Obstruct

1985
[Disorders of immunologic profile and interferon response in lung diseases].
    Klinicheskaia meditsina, 1987, Volume: 65, Issue:12

    Topics: Adjuvants, Immunologic; Adult; Dipyridamole; Humans; Interferon Inducers; Interferon Type I; Lung Di

1987