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dipyridamole and Ischemic Attack, Transient

dipyridamole has been researched along with Ischemic Attack, Transient in 194 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"The aim of this study is to investigate the effect of gradual dipyridamole titration and the incidence of dipyridamole-induced headache in patients with ischemic stroke or transient ischemic attack (TIA)."9.51Effects of Dose Titration on Dipyridamole-Induced Headache: A Randomized, Double-Blind Clinical Trial. ( Cha, JK; Chang, DI; Chang, JY; Chung, JW; Hong, KS; Jung, KH; Kang, MK; Kim, BK; Kim, HY; Lee, KY; Lee, SJ; Park, JM; Park, MS; Rha, JH; Shin, DI; Yoon, BW, 2022)
"We showed that slower than standard dose escalation of dipyridamole in combination therapy with acetylsalicylic acid does not reduce headaches as a side effect."9.19The effect of a slower than standard dose escalation scheme for dipyridamole on headaches in secondary prevention therapy of strokes: a randomized, open-label trial (DOSE). ( de Vogel, EM; de Vos-Koppelaar, NC; Dieleman, HG; Kerkhoff, H; Zock, E, 2014)
" Platelet surface marker expression, leucocyte-platelet complex formation and inhibition of platelet function at high shear stress as detected by the PFA-100® Collagen-Adenosine-diphosphate (C-ADP) and Collagen-Epinephrine cartridges was assessed in 52 patients within 4 weeks of transient ischaemic attack (TIA) or ischaemic stroke on aspirin, and then 14 d (14 d) and >90 d (90 d) after adding dipyridamole."9.15Enhanced ex vivo inhibition of platelet function following addition of dipyridamole to aspirin after transient ischaemic attack or ischaemic stroke: first results from the TRinity AntiPlatelet responsiveness (TrAP) study. ( Collins, DR; Coughlan, T; Egan, B; Feeley, TM; Kinsella, JA; McCabe, DJ; Murphy, RP; O'Neill, D; Tierney, S; Tobin, WO, 2011)
"Secondary pharmacological prevention of ischemic stroke or transient ischemic attack (TIA) is often provided with acetylsalicylic acid (ASA), dipyridamole (DP) or a combination of the two."9.14Dipyridamole-associated headache in stroke patients--interindividual differences? ( Lökk, J, 2009)
"To determine the prevalence of platelet nonresponsiveness to aspirin treatment for secondary stroke prophylaxis, the authors studied consecutive patients during a 29-month period."9.13Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. ( Bates, V; Forrest, A; Gengo, FM; Gengo, MF; Hourihane, M; Rainka, M; Robson, M, 2008)
"Combination of low-dose aspirin and modified-release dipyridamole (ASA+MR-DP) provides a significantly increased benefit in stroke prevention over aspirin alone."9.12Dose titration to reduce dipyridamole-related headache. ( Chang, YJ; Lee, TH; Ryu, SJ, 2006)
"We performed meta-analyses to assess the effectiveness and safety of combination therapy with aspirin and dipyridamole (A+D) versus aspirin (A) alone in secondary prevention after transient ischemic attack (TIA) or stroke of presumed arterial origin within one week and six months."8.89The efficacy and safety of aspirin plus dipyridamole versus aspirin in secondary prevention following TIA or stroke: a meta-analysis of randomized controlled trials. ( Li, X; Zhou, G; Zhou, S; Zhou, X, 2013)
"The combination of aspirin and dipyridamole is more effective than aspirin alone in patients with TIA or ischaemic stroke of presumed arterial origin in the secondary prevention of stroke and other vascular events."8.84Dipyridamole plus aspirin versus aspirin alone in secondary prevention after TIA or stroke: a meta-analysis by risk. ( Algra, A; Bath, PM; Diener, HC; Gray, LJ; Guiraud-Chaumeil, B; Halkes, PH; Yatsu, FM, 2008)
"This meta-analysis systematically reviewed randomized controlled trials comparing aspirin plus dipyridamole with aspirin alone in patients with stroke and TIA to determine the efficacy of these agents in preventing recurrent cerebral and systemic vascular events."8.84Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis. ( Gorelick, PB; Nguyen, D; Verro, P, 2008)
"Dipyridamole, given alone or with aspirin, reduces stroke recurrence in patients with previous ischemic cerebrovascular disease."8.82Dipyridamole for preventing recurrent ischemic stroke and other vascular events: a meta-analysis of individual patient data from randomized controlled trials. ( Bath, PM; Bousser, MG; Davalos, A; Dewey, ME; Diener, HC; Guiraud-Chaumeil, B; Leonardi-Bee, J; Sivenius, J; Yatsu, F, 2005)
"This prospective, observational study assessed TIA/ischaemic stroke patients before (baseline; N = 60), at 14 ±7 days (14d, N = 39) and ≥ 90 days (90d, N = 31) after adding dipyridamole to aspirin."8.12Assessment of on-treatment platelet reactivity at high and low shear stress and platelet activation status after the addition of dipyridamole to aspirin in the early and late phases after TIA and ischaemic stroke. ( Collins, DR; Coughlan, T; Cox, D; Egan, B; Lim, ST; Lim, SY; McCabe, DJH; McCarthy, AJ; Murphy, SJX; Murphy, SM; O'Neill, D; Smith, DR; Tierney, S, 2022)
"Japanese guidelines recommend aspirin 160-300 mg/day, starting within 48 h, for patients with acute cerebral infarction."7.80Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan. ( Inuyama, L; Mizuno, O; Sakaguchi, T; Takahashi, S; Yamada, T, 2014)
"Long term triple antiplatelet therapy was asociated with a significant increase in adverse events and bleeding rates, and their severity, and a trend to increased discontinuations."6.73A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility. ( Bath, PM; England, T; Gray, LJ; Sare, GM; Sprigg, N; Willmot, MR; Zhao, L, 2008)
"Aspirin has been convincingly shown to reduce stroke and death in men with transient ischemic attacks (it may possibly be beneficial to women also), myocardial infarction and death in patients with unstable angina, thromboembolic complications associated with artificial heart valves in patients receiving oral anticoagulants (although gastrointestinal bleeding is prohibitive with this combination), and thrombotic occlusion of silicone rubber arteriovenous cannulae in uremic patients undergoing hemodialysis."6.15Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis. ( Harker, LA, 1986)
"The aim of this study is to investigate the effect of gradual dipyridamole titration and the incidence of dipyridamole-induced headache in patients with ischemic stroke or transient ischemic attack (TIA)."5.51Effects of Dose Titration on Dipyridamole-Induced Headache: A Randomized, Double-Blind Clinical Trial. ( Cha, JK; Chang, DI; Chang, JY; Chung, JW; Hong, KS; Jung, KH; Kang, MK; Kim, BK; Kim, HY; Lee, KY; Lee, SJ; Park, JM; Park, MS; Rha, JH; Shin, DI; Yoon, BW, 2022)
"This is the first case report of a circulatory collapse induced by an oral intake of dipyridamole."5.48Oral Dipyridamole-Associated Circulatory Collapse. ( Jolma, P; Ollikainen, J; Uurto, I, 2018)
"The European/Australasian stroke prevention in reversible ischaemia trial (ESPRIT) confirms that long-term administration of the combination acetylsalicylic acid and dipyridamole is more effective than acetylsalicylic acid in reducing the risk of vascular events after cerebral ischaemia of arterial origin."5.33[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed]. ( De Keyser, JH; Luijckx, GJ, 2006)
"We showed that slower than standard dose escalation of dipyridamole in combination therapy with acetylsalicylic acid does not reduce headaches as a side effect."5.19The effect of a slower than standard dose escalation scheme for dipyridamole on headaches in secondary prevention therapy of strokes: a randomized, open-label trial (DOSE). ( de Vogel, EM; de Vos-Koppelaar, NC; Dieleman, HG; Kerkhoff, H; Zock, E, 2014)
" Platelet surface marker expression, leucocyte-platelet complex formation and inhibition of platelet function at high shear stress as detected by the PFA-100® Collagen-Adenosine-diphosphate (C-ADP) and Collagen-Epinephrine cartridges was assessed in 52 patients within 4 weeks of transient ischaemic attack (TIA) or ischaemic stroke on aspirin, and then 14 d (14 d) and >90 d (90 d) after adding dipyridamole."5.15Enhanced ex vivo inhibition of platelet function following addition of dipyridamole to aspirin after transient ischaemic attack or ischaemic stroke: first results from the TRinity AntiPlatelet responsiveness (TrAP) study. ( Collins, DR; Coughlan, T; Egan, B; Feeley, TM; Kinsella, JA; McCabe, DJ; Murphy, RP; O'Neill, D; Tierney, S; Tobin, WO, 2011)
"Secondary pharmacological prevention of ischemic stroke or transient ischemic attack (TIA) is often provided with acetylsalicylic acid (ASA), dipyridamole (DP) or a combination of the two."5.14Dipyridamole-associated headache in stroke patients--interindividual differences? ( Lökk, J, 2009)
"To determine the prevalence of platelet nonresponsiveness to aspirin treatment for secondary stroke prophylaxis, the authors studied consecutive patients during a 29-month period."5.13Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. ( Bates, V; Forrest, A; Gengo, FM; Gengo, MF; Hourihane, M; Rainka, M; Robson, M, 2008)
"Combination of low-dose aspirin and modified-release dipyridamole (ASA+MR-DP) provides a significantly increased benefit in stroke prevention over aspirin alone."5.12Dose titration to reduce dipyridamole-related headache. ( Chang, YJ; Lee, TH; Ryu, SJ, 2006)
"Results of trials of aspirin and dipyridamole combined versus aspirin alone for the secondary prevention of vascular events after ischaemic stroke of presumed arterial origin are inconsistent."5.12Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial. ( Algra, A; Halkes, PH; Kappelle, LJ; Koudstaal, PJ; van Gijn, J, 2006)
"The second European Stroke Prevention Study investigated the prevention of stroke and/or death in 6602 patients with transient ischaemic attack or stroke with aspirin (25 mg b."5.09Cardiac safety in the European Stroke Prevention Study 2 (ESPS2). ( Bertrand-Hardy, JM; Darius, H; Diener, HC; Humphreys, M, 2001)
"Combination therapy with dipyridamole and aspirin reduces not only the risk of cerebrovascular ischemic events but also the risk of myocardial infarction."5.07Antiplatelet therapy is effective in primary prevention of myocardial infarction in patients with a previous cerebrovascular ischemic event. ( Laakso, M; Lowenthal, A; Riekkinen, PJ; Sivenius, J; Smets, P, 1993)
"We compared the outcomes of 2,500 patients who suffered from previous cerebrovascular disorders (transient ischemic attacks, reversible ischemic neurologic deficits, or completed strokes) treated with acetylsalicylic acid plus dipyridamole or matched placebo and followed for 2 years."5.06European Stroke Prevention Study. ESPS Group. ( , 1990)
"Cilostazol was significantly more effective than aspirin and clopidogrel alone in the long-term prevention of serious vascular events in patients with prior non-cardioembolic ischaemic stroke or transient ischaemic attack."4.93Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis. ( Guo, ZN; Jin, H; Niu, PP; Xing, YQ; Yang, Y, 2016)
"Recurrent stroke risk did not differ between patients receiving dual-antiplatelet therapy and those receiving aspirin monotherapy (relative risk [RR], 0."4.89Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis. ( Hong, KS; Lee, M; Ovbiagele, B; Rao, NM; Saver, JL; Wu, YL, 2013)
"We performed meta-analyses to assess the effectiveness and safety of combination therapy with aspirin and dipyridamole (A+D) versus aspirin (A) alone in secondary prevention after transient ischemic attack (TIA) or stroke of presumed arterial origin within one week and six months."4.89The efficacy and safety of aspirin plus dipyridamole versus aspirin in secondary prevention following TIA or stroke: a meta-analysis of randomized controlled trials. ( Li, X; Zhou, G; Zhou, S; Zhou, X, 2013)
"The combination of aspirin and dipyridamole is more effective than aspirin alone in patients with TIA or ischaemic stroke of presumed arterial origin in the secondary prevention of stroke and other vascular events."4.84Dipyridamole plus aspirin versus aspirin alone in secondary prevention after TIA or stroke: a meta-analysis by risk. ( Algra, A; Bath, PM; Diener, HC; Gray, LJ; Guiraud-Chaumeil, B; Halkes, PH; Yatsu, FM, 2008)
"Low dose aspirin is effective in secondary stroke prevention."4.84Prevention of secondary stroke and transient ischaemic attack with antiplatelet therapy: the role of the primary care physician [corrected]. ( Kirshner, HS, 2007)
"This meta-analysis systematically reviewed randomized controlled trials comparing aspirin plus dipyridamole with aspirin alone in patients with stroke and TIA to determine the efficacy of these agents in preventing recurrent cerebral and systemic vascular events."4.84Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis. ( Gorelick, PB; Nguyen, D; Verro, P, 2008)
"Dipyridamole, given alone or with aspirin, reduces stroke recurrence in patients with previous ischemic cerebrovascular disease."4.82Dipyridamole for preventing recurrent ischemic stroke and other vascular events: a meta-analysis of individual patient data from randomized controlled trials. ( Bath, PM; Bousser, MG; Davalos, A; Dewey, ME; Diener, HC; Guiraud-Chaumeil, B; Leonardi-Bee, J; Sivenius, J; Yatsu, F, 2005)
"Using the key terms acute coronary syndrome, atherothrombosis, ischemic stroke, myocardial infarction, MI, peripheral arterial disease, TIA, transient ischemic attack, unstable angina,aspirin,ticlopidine,dipyridamole, and clopidogrel, we searched the MEDLINE database as well as the trial register of the Cochrane Groups to identify studies published from 1960 to August 2004."4.82Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease. ( Anand, SS; Tran, H, 2004)
" The search terms used were dipyridamole, aspirin, acetylsalicylic acid, ischemic stroke, and cerebrovascular disorders."4.81Analysis of trials evaluating combinations of acetylsalicylic acid and dipyridamole in the secondary prevention of stroke. ( Redman, AR; Ryan, GJ, 2001)
" Dipyridamole co-formulated with aspirin has been shown to increase the relative reduction in risk of second stroke in patients with prior stroke/transient ischaemic attack beyond that obtaining with aspirin alone."4.81Dipyridamole may be used safely in patients with ischaemic heart disease. ( Bertrand-Hardy, JM; Humphreys, DM; Palluk, R; Schumacher, H; Street, J, 2002)
"Aspirin is the treatment of first choice for long-term secondary prevention of vascular events in patients with confirmed non-cardioembolic ischaemic stroke or TIA."4.80Prevention of ischaemic stroke--antiplatelets. ( Brown, MM; McCabe, DJ, 2000)
"This prospective, observational study assessed TIA/ischaemic stroke patients before (baseline; N = 60), at 14 ±7 days (14d, N = 39) and ≥ 90 days (90d, N = 31) after adding dipyridamole to aspirin."4.12Assessment of on-treatment platelet reactivity at high and low shear stress and platelet activation status after the addition of dipyridamole to aspirin in the early and late phases after TIA and ischaemic stroke. ( Collins, DR; Coughlan, T; Cox, D; Egan, B; Lim, ST; Lim, SY; McCabe, DJH; McCarthy, AJ; Murphy, SJX; Murphy, SM; O'Neill, D; Smith, DR; Tierney, S, 2022)
"We pooled individual patient data from 6 randomized clinical trials (CAPRIE [Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events], ESPS-2 [European Stroke Prevention Study-2], MATCH [Management of Atherothrombosis With Clopidogrel in High-Risk Patients], CHARISMA [Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance], ESPRIT [European/Australasian Stroke Prevention in Reversible Ischemia Trial], and PRoFESS [Prevention Regimen for Effectively Avoiding Second Strokes]) investigating antiplatelet therapy in the subacute or chronic phase after noncardioembolic transient ischemic attack or stroke."4.02Balancing Benefits and Risks of Long-Term Antiplatelet Therapy in Noncardioembolic Transient Ischemic Attack or Stroke. ( Algra, A; Bath, PM; Csiba, L; Diener, HC; Greving, JP; Hacke, W; Hilkens, NA; Kappelle, LJ; Koudstaal, PJ; Leys, D; Mas, JL; Sacco, RL, 2021)
"Japanese guidelines recommend aspirin 160-300 mg/day, starting within 48 h, for patients with acute cerebral infarction."3.80Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan. ( Inuyama, L; Mizuno, O; Sakaguchi, T; Takahashi, S; Yamada, T, 2014)
"In acute ischemic stroke and transient ischemic attack (TIA), aspirin is recommended to all patients (except immediately following thrombolysis)."3.74[Antithrombotic therapy in ischemic stroke and transient ischemic attack]. ( Husted, SE; Overgaard, K; Poulsen, TS, 2007)
"Clopidogrel and dipyridamole-aspirin are used frequently after stroke or transient ischemic attack."3.74Trends in usage of alternative antiplatelet therapy after stroke and transient ischemic attack. ( Hills, NK; Johnston, SC, 2008)
"Within a cross-sectional study, nested in a cohort we identified 931 patients with a recent ischemic stroke or TIA who were discharged with OAC or with one of the antiplatelet medications aspirin, clopidogrel, or the combination of aspirin and extended-release dipyridamole."3.71Current strategies of secondary prevention after a cerebrovascular event: the Vienna stroke registry. ( Lalouschek, W; Lang, W; Müllner, M, 2001)
"Compared with aspirin alone, use of the new antiplatelet regimens, including aspirin combined with dipyridamole and clopidogrel bisulfate, has been found to further reduce the risk of stroke and other vascular events in patients who have experienced stroke or transient ischemic attack."3.70Cost-effectiveness of new antiplatelet regimens used as secondary prevention of stroke or transient ischemic attack. ( Bounameaux, H; Gaspoz, JM; Sarasin, FP, 2000)
"Bleeding was defined using the International Society on Thrombosis and Haemostasis five-level ordered categorical scale: fatal, major, moderate, minor, none."3.30Bleeding with intensive versus guideline antiplatelet therapy in acute cerebral ischaemia. ( Appleton, JP; Bath, PM; Christensen, H; Dineen, RA; England, TJ; James, M; Krishnan, K; Montgomery, AA; Ranta, A; Robinson, TG; Sprigg, N; Woodhouse, LJ, 2023)
"In these patients with type 2 diabetes and a history of TIA, patterns of platelet inhibition differed significantly according to whether treatment was with ER-DP+ASA or clopidogrel with or without ASA."2.73Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-b ( Hanley, DF; Malinin, AI; Pokov, AN; Serebruany, VL, 2008)
"Long term triple antiplatelet therapy was asociated with a significant increase in adverse events and bleeding rates, and their severity, and a trend to increased discontinuations."2.73A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility. ( Bath, PM; England, T; Gray, LJ; Sare, GM; Sprigg, N; Willmot, MR; Zhao, L, 2008)
"Dipyridamole was associated with a slight increase in headache, which resolved in most patients if therapy was continued."2.69Secondary stroke prevention with low-dose aspirin, sustained release dipyridamole alone and in combination. ESPS Investigators. European Stroke Prevention Study. ( Forbes, CD, 1998)
"Patients with prior stroke or transient ischemic attack (TIA) were randomized to treatment with ASA alone (50 mg daily), modified-release dipyridamole alone (400 mg daily), the two agents in a combined formulation, or placebo."2.68European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. ( Cunha, L; Diener, HC; Forbes, C; Lowenthal, A; Sivenius, J; Smets, P, 1996)
"Bleeding is the main adverse effect of antiplatelet therapy and is potentially life threatening."2.53Prediction models for intracranial hemorrhage or major bleeding in patients on antiplatelet therapy: a systematic review and external validation study. ( Algra, A; Greving, JP; Hilkens, NA, 2016)
"Bleeding is potentially the most significant antiplatelet-associated side effect."2.47Review and management of side effects associated with antiplatelet therapy for prevention of recurrent cerebrovascular events. ( Guthrie, R, 2011)
"Aspirin has been shown to reduce the risk of recurrent strokes, and the combination of aspirin and dipyridamole has repeatedly been shown to outperform aspirin alone."2.46Current guidelines on antiplatelet agents for secondary prevention of noncardiogenic stroke: an evidence-based review. ( Fung, K; Simmons, BB; Yeo, A, 2010)
"Stroke is a leading cause of death and the primary cause of serious, long-term disability in the United States."2.44Combination antiplatelet agents for secondary prevention of ischemic stroke. ( Saseen, JJ; Vande Griend, JP, 2008)
"Patients who have transient ischemic attack (TIA) or ischemic stroke are at a high risk of having a first or recurrent stroke."2.44Antiplatelet agents and randomized trials. ( Diener, HC, 2007)
"Patients suffering from a transient ischemic attack or stroke are particularly vulnerable to subsequent stroke."2.41Update on antiplatelet therapy for stroke prevention. ( Elkind, MS; Sacco, RL, 2000)
"Dipyridamole can inhibit both platelet adhesion and aggregation by raising the platelet cyclic AMP level through phosphodiesterase inhibition."2.37Aspirin and other platelet-aggregation inhibiting drugs. ( Gallus, AS, 1985)
"This is the first case report of a circulatory collapse induced by an oral intake of dipyridamole."1.48Oral Dipyridamole-Associated Circulatory Collapse. ( Jolma, P; Ollikainen, J; Uurto, I, 2018)
"Dipyridamole is an antiplatelet agent and a vasodilator which is increasingly being used for the secondary prevention of ischaemic stroke and transient ischemic attack, either alone or in combination with acetylsalicylic acid."1.34Musical hallucinations induced by drugs. ( Cheung, G; Tomar, A, 2007)
"Patients with transient ischemic attack (TIA) or ischemic stroke carry a risk of recurrent stroke of between 5% and 20% per year."1.33Secondary stroke prevention with antiplatelet drugs: have we reached the ceiling? ( Diener, HC, 2006)
"The European/Australasian stroke prevention in reversible ischaemia trial (ESPRIT) confirms that long-term administration of the combination acetylsalicylic acid and dipyridamole is more effective than acetylsalicylic acid in reducing the risk of vascular events after cerebral ischaemia of arterial origin."1.33[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed]. ( De Keyser, JH; Luijckx, GJ, 2006)
"62 patients with transient ischemic attack (TIA), 60 with reversible ischemic neurologic deficit (RIND) and 57 with stroke with minimum residuum (SMR) were followed, in a retrospective survey, from the first 7 days to the 3rd month of evolution."1.27Short-term outcome of medically treated patients with transient ischemic attacks, reversible ischemic neurologic deficits and strokes with minimum residuum. ( Calandre, L; Molina, JA, 1985)
"Recurrent transient ischemic attack or amaurosis fugax occurred more frequently (P less than 0."1.27Enteric-coated acetylsalicylic acid plus dipyridamole compared with anticoagulants in the prevention of ischemic events in patients with transient ischemic attacks. ( Eriksson, SE, 1985)
"In patients with transient ischemic attack (TIA), the risk of stroke increases greatly, especially in the months immediately following the initial attack."1.27Transient ischemic attacks. Strategies for minimizing stroke risk. ( Furlan, AJ, 1984)
"and sulfinpyrazone have been tested in several large scale clinical trials."1.26[Antiplatelet drugs (author's transl)]. ( Dechavanne, M; Follea, G; Trzeciak, MC, 1979)
"Eight patients with transient ischemic attacks, and three with partial nonprogressive strokes associated with mitral valve prolapse, are reported."1.26TIA, stroke, and mitral valve prolapse. ( Watson, RT, 1979)
"In patients with transient ischemic attacks, particularly males with appropriate carotid lesions, aspirin therapy reduces the frequency of transient ischemic attacks and possibly the incidence of stroke and death."1.26[Action mechanism and clinical indications for thrombocyte aggregation inhibitors]. ( Oelz, O, 1979)
"The authors report 22 cases of transient ischemic attacks (TIA's) manifested by amaurosis fugax or hemiparesis or paresthesia of less than 24 hours' duration."1.26Transient ischemic attacks due to increased platelet aggregation and adhesiveness. Ultrastructural and functional correlation. ( al-Mefty, O; Marano, G; Nugent, GR; Raiaraman, S; Rodman, N, 1979)

Research

Studies (194)

TimeframeStudies, this research(%)All Research%
pre-199073 (37.63)18.7374
1990's21 (10.82)18.2507
2000's69 (35.57)29.6817
2010's25 (12.89)24.3611
2020's6 (3.09)2.80

Authors

AuthorsStudies
Kang, MK1
Cha, JK1
Chang, DI1
Kim, HY1
Chung, JW1
Jung, KH1
Hong, KS2
Chang, JY1
Rha, JH1
Park, JM1
Kim, BK1
Lee, SJ1
Park, MS1
Lee, KY1
Shin, DI1
Yoon, BW1
Shah, J1
Liu, S1
Yu, W1
Lim, ST1
Murphy, SJX1
Murphy, SM1
Coughlan, T5
O'Neill, D5
Tierney, S4
Egan, B4
Collins, DR4
McCarthy, AJ1
Lim, SY1
Smith, DR1
Cox, D2
McCabe, DJH1
Scalia, L1
Calderone, D1
Capodanno, D1
Woodhouse, LJ2
Appleton, JP2
Christensen, H2
Dineen, RA2
England, TJ2
James, M2
Krishnan, K2
Montgomery, AA2
Ranta, A2
Robinson, TG2
Sprigg, N3
Bath, PM6
Hilkens, NA2
Algra, A9
Diener, HC17
Csiba, L1
Hacke, W1
Kappelle, LJ2
Koudstaal, PJ2
Leys, D2
Mas, JL1
Sacco, RL3
Greving, JP2
Beridze, M1
Duley, L1
Flaherty, K1
Havard, D1
Heptinstall, S1
Markus, HS1
Pocock, SJ1
Randall, M1
Scutt, P1
Venables, GS1
Jolma, P1
Ollikainen, J1
Uurto, I1
Zuurbier, SM1
Vermeer, SE1
Hilkens, PH1
Roos, YB1
Edwards, D1
Fletcher, K1
Deller, R1
McManus, R1
Lasserson, D1
Giles, M1
Sims, D1
Norrie, J1
McGuire, G1
Cohn, S1
Whittle, F1
Hobbs, V1
Weir, C1
Mant, J1
Li, X1
Zhou, G1
Zhou, X1
Zhou, S1
Lee, M1
Saver, JL1
Rao, NM1
Wu, YL1
Ovbiagele, B1
Ding, D1
Takahashi, S1
Mizuno, O1
Sakaguchi, T1
Yamada, T1
Inuyama, L1
Tobin, WO4
Kinsella, JA4
Kavanagh, GF2
O'Donnell, JS2
McGrath, RT1
Feeley, TM3
Murphy, RP4
McCabe, DJ5
de Vos-Koppelaar, NC1
Kerkhoff, H1
de Vogel, EM1
Zock, E1
Dieleman, HG1
Niu, PP1
Guo, ZN1
Jin, H1
Xing, YQ1
Yang, Y1
Halkes, PH2
Gray, LJ2
Guiraud-Chaumeil, B3
Yatsu, FM2
England, T1
Willmot, MR1
Zhao, L1
Sare, GM1
Lam, SK1
Owen, A1
Vande Griend, JP1
Saseen, JJ1
Rouhl, RP1
Lodder, J1
Biller, J1
Khalil, S1
Mohanaruban, K1
Haq, S1
Lökk, J1
Schwab, S1
Gomez, CR1
Qureshi, AI1
Dengler, R1
Schwartz, A1
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Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
EARLY: Prospective, Randomised, National, Multi-centre, Open-label, Blinded Endpoint Study to Compare Aggrenox b.i.d. (200 mg Dipyridamole MR + 25 mg Acetylsalicylic Acid) When Started Within 24 Hours of Stroke Onset on an Acute Stroke Unit, and Aggrenox [NCT00562588]Phase 4551 participants (Actual)Interventional2007-07-31Completed
ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial[NCT00161070]Phase 44,500 participants Interventional1997-07-31Completed
Does Pretreatment With Persantin Reduce Periprocedural Troponin-I Release in Patients Undergoing Elective Single Vessel PCI[NCT00767663]Phase 430 participants (Actual)Interventional2008-10-31Completed
Technical Development for Pediatric Cardiovascular MRI[NCT02892136]5,000 participants (Anticipated)Observational2013-05-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in DWI (Diffuse-Weighted Imaging) at Day 8

MRI was performed to assess growth in stroke lesion volume by diffusion-weighted imaging (DWI). DWI was to give evidence of the development of the ischaemic lesion corresponding to the evolved stroke. (NCT00562588)
Timeframe: Baseline and day 8

InterventionmL (Median)
Aspirin for 7 Days, Followed by Aggrenox-0.0600
Aggrenox0.0000

Change From Baseline in DWI (Diffuse-Weighted Imaging) at Day 90

MRI was performed to assess growth in stroke lesion volume by diffusion-weighted imaging (DWI). DWI was to give evidence of the development of the ischaemic lesion corresponding to the evolved stroke. (NCT00562588)
Timeframe: Baseline and day 90

InterventionmL (Median)
Aspirin for 7 Days, Followed by Aggrenox-0.8400
Aggrenox-0.7100

Change From Baseline in FLAIR (Fluid-Attenuated Inversion Recovery) at Day 8

MRI was performed to assess growth in stroke lesion volume by fluid-attenuated inversion recovery (FLAIR). (NCT00562588)
Timeframe: Baseline and day 8

InterventionmL (Median)
Aspirin for 7 Days, Followed by Aggrenox0.4100
Aggrenox0.3300

Change From Baseline in FLAIR (Fluid-Attenuated Inversion Recovery) at Day 90.

MRI was performed to assess growth in stroke lesion volume by fluid-attenuated inversion recovery (FLAIR). (NCT00562588)
Timeframe: Baseline and day 90

InterventionmL (Median)
Aspirin for 7 Days, Followed by Aggrenox0.1900
Aggrenox0.1150

Change From Baseline in NIHSS (National Institutes of Health Stroke Scale)

The NIHSS is a systematic assessment tool that provides a quantitative measure of stroke-related neurologic deficit. Values range from 0 (no deficit) to 42 (dead) (NCT00562588)
Timeframe: Baseline and 90 days

InterventionUnits on a scale (Median)
Aspirin for 7 Days, Followed by Aggrenox-2
Aggrenox-2

Change From Baseline in NIHSS (National Institutes of Health Stroke Scale) at Day 8

The NIHSS is a systematic assessment tool that provides a quantitative measure of stroke-related neurologic deficit. Values range from 0 (no deficit) to 42 (dead) (NCT00562588)
Timeframe: Baseline and 8 days

Interventionunits on a scale (Median)
Aspirin for 7 Days, Followed by Aggrenox-1.0
Aggrenox-1.0

Change of Special Biochemical Laboratory Value - MCP-1

Changes of special biochemical laboratory value (MCP-1) from baseline to day 8 - centralised, blinded assessment by a specialised central clinical laboratory (NCT00562588)
Timeframe: 8 days

Interventionµg/mL (Geometric Mean)
Aspirin for 7 Days, Followed by Aggrenox1.06
Aggrenox1.08

Change of Special Biochemical Laboratory Value- CRP

Changes of special biochemical laboratory values (CRP) from baseline to day 8 - centralised, blinded assessment by a specialised central clinical laboratory (NCT00562588)
Timeframe: 8 days

Interventionmg/L (Geometric Mean)
Aspirin for 7 Days, Followed by Aggrenox1.27
Aggrenox1.17

Change of Special Biochemical Laboratory Value- MMP-9

Changes of special biochemical laboratory value (MMP-9) from baseline to day 8 - centralised, blinded assessment by a specialised central clinical laboratory (NCT00562588)
Timeframe: 8 days

Interventionng/mL (Geometric Mean)
Aspirin for 7 Days, Followed by Aggrenox0.974
Aggrenox0.983

Patients With Relevant Event (Death, Non-fatal Stroke, Transient Ischaemic Attack (TIA), Myocardial Infarction (MI), Bleeding)

(NCT00562588)
Timeframe: 90 days

Interventionparticipants (Number)
Aspirin for 7 Days, Followed by Aggrenox38
Aggrenox28

Telephone Modified Rankin Scale (Centralised, Blinded Assessment)

The modified Rankin Scale (mRS) is a scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke. The scale runs from 0-6, running from perfect health without symptoms to death. Best value - 0 (No symptoms), worst value - 6 (Dead) (NCT00562588)
Timeframe: 90 days

,
Interventionparticipants (Number)
0123456
Aggrenox708462163245
Aspirin for 7 Days, Followed by Aggrenox587550303164

Telephone Modified Rankin Scale (Centralised, Blinded Assessment) at Day 8

The modified Rankin Scale (mRS) is a scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke. The scale runs from 0-6, running from perfect health without symptoms to death. Best value - 0 (No symptoms), worst value - 6 (Dead) (NCT00562588)
Timeframe: 8 days

,
Interventionparticipants (Number)
0123456Missing
Aggrenox4774523844828
Aspirin for 7 Days, Followed by Aggrenox46594239511205

Reviews

53 reviews available for dipyridamole and Ischemic Attack, Transient

ArticleYear
Contemporary antiplatelet therapy for secondary stroke prevention: a narrative review of current literature and guidelines.
    Stroke and vascular neurology, 2022, Volume: 7, Issue:5

    Topics: Aspirin; Brain Ischemia; Cilostazol; Clopidogrel; Dipyridamole; Humans; Ischemic Attack, Transient;

2022
Antiplatelet therapy after noncardioembolic ischemic stroke or transient ischemic attack.
    Expert review of clinical pharmacology, 2022, Volume: 15, Issue:9

    Topics: Anticoagulants; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Factor XI; Fibrinolyt

2022
[Secondary prevention with clopidogrel after TIA or stroke].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:25

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; N

2013
The efficacy and safety of aspirin plus dipyridamole versus aspirin in secondary prevention following TIA or stroke: a meta-analysis of randomized controlled trials.
    Journal of the neurological sciences, 2013, Sep-15, Volume: 332, Issue:1-2

    Topics: Aged; Aspirin; Dipyridamole; Female; Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Male;

2013
Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis.
    Annals of internal medicine, 2013, Oct-01, Volume: 159, Issue:7

    Topics: Anticoagulants; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Human

2013
Prediction models for intracranial hemorrhage or major bleeding in patients on antiplatelet therapy: a systematic review and external validation study.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:1

    Topics: Algorithms; Anticoagulants; Aspirin; Brain Ischemia; Calibration; Cerebral Hemorrhage; Dipyridamole;

2016
Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis.
    BMJ open, 2016, Mar-17, Volume: 6, Issue:3

    Topics: Aspirin; Cilostazol; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hemorrhage; Humans; Ische

2016
Dipyridamole plus aspirin versus aspirin alone in secondary prevention after TIA or stroke: a meta-analysis by risk.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyridamole; Drug Therapy, Combination; Humans; I

2008
Combination antiplatelet agents for secondary prevention of ischemic stroke.
    Pharmacotherapy, 2008, Volume: 28, Issue:10

    Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combinat

2008
ESPRIT: is aspirin plus dipyridamole superior to aspirin alone in TIA or minor stroke patients?
    Expert review of neurotherapeutics, 2008, Volume: 8, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; H

2008
Antiplatelet therapy in ischemic stroke: variability in clinical trials and its impact on choosing the appropriate therapy.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Brain Ischemia; Clinical Trials as Topic;

2009
Current guidelines on antiplatelet agents for secondary prevention of noncardiogenic stroke: an evidence-based review.
    Postgraduate medicine, 2010, Volume: 122, Issue:2

    Topics: American Heart Association; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; I

2010
Oral antiplatelet therapy in stroke prevention. Minireview.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2010, Volume: 154, Issue:3

    Topics: Administration, Oral; Aspirin; Clopidogrel; Dipyridamole; Drug Combinations; Humans; Ischemic Attack

2010
Secondary prevention in the acute and early chronic phase after ischaemic stroke and transient ischaemic attacks with antiplatelet drugs--is antiplatelet monotherapy still reasonable?
    International journal of clinical practice, 2011, Volume: 65, Issue:5

    Topics: Abciximab; Acute Disease; Antibodies, Monoclonal; Aspirin; Chronic Disease; Clopidogrel; Delayed-Act

2011
Review and management of side effects associated with antiplatelet therapy for prevention of recurrent cerebrovascular events.
    Advances in therapy, 2011, Volume: 28, Issue:6

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Headache; Hemorrhage; Humans; Ischemi

2011
New insights in antiplatelet therapy for patients with ischemic stroke.
    The neurologist, 2011, Volume: 17, Issue:5

    Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Humans; I

2011
Antiplatelets in secondary stroke prevention: should clopidogrel be the first choice?
    Postgraduate medical journal, 2012, Volume: 88, Issue:1035

    Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Ischemia; Ischemic Attack, Transient; Platelet Aggregati

2012
Dipyridamole for preventing stroke and other vascular events in patients with vascular disease.
    The Cochrane database of systematic reviews, 2003, Issue:1

    Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Fibrinolytic Agents; Humans; Ische

2003
Antiplatelet treatment for secondary prevention of acute ischemic stroke and transient ischemic attacks: mechanisms, choices and possible emerging patterns of use.
    Expert review of cardiovascular therapy, 2003, Volume: 1, Issue:4

    Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dipyridamole; Drug Combinations; Human

2003
Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease.
    JAMA, 2004, Oct-20, Volume: 292, Issue:15

    Topics: Administration, Oral; Angina Pectoris; Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopido

2004
Dipyridamole for preventing recurrent ischemic stroke and other vascular events: a meta-analysis of individual patient data from randomized controlled trials.
    Stroke, 2005, Volume: 36, Issue:1

    Topics: Aspirin; Blood Pressure; Brain Ischemia; Dipyridamole; Drug Therapy, Combination; Female; Humans; Is

2005
What is the role of dipyridamole in long-term secondary prevention after an ischemic stroke or transient ischemic attack?
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2005, Oct-25, Volume: 173, Issue:9

    Topics: Aspirin; Dipyridamole; Evidence-Based Medicine; Humans; Ischemic Attack, Transient; Platelet Aggrega

2005
Dipyridamole for preventing stroke and other vascular events in patients with vascular disease.
    The Cochrane database of systematic reviews, 2006, Apr-19, Issue:2

    Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Fibrinolytic Agents; Humans; Ische

2006
Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?
    Circulation, 2007, Mar-27, Volume: 115, Issue:12

    Topics: Aspirin; Atherosclerosis; Cilostazol; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Dipyr

2007
Dipyridamole with aspirin is better than aspirin alone in preventing vascular events after ischaemic stroke or TIA.
    BMJ (Clinical research ed.), 2007, Apr-28, Volume: 334, Issue:7599

    Topics: Aspirin; Brain Ischemia; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient

2007
Dipyridamole for preventing stroke and other vascular events in patients with vascular disease.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:3

    Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Fibrinolytic Agents; Humans; Ische

2007
Antiplatelet therapy in cerebrovascular disease: implications of Management of Artherothrombosis with Clopidogrel in High-risk Patients and the Clopidogrel for High Artherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance studies' resu
    Clinical cardiology, 2007, Volume: 30, Issue:12

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Embolism, C

2007
Prevention of secondary stroke and transient ischaemic attack with antiplatelet therapy: the role of the primary care physician [corrected].
    International journal of clinical practice, 2007, Volume: 61, Issue:10

    Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Dipyridamole; Drug Therapy, Combination; Family P

2007
Antiplatelet agents and randomized trials.
    Reviews in neurological diseases, 2007,Fall, Volume: 4, Issue:4

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; P

2007
Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis.
    Stroke, 2008, Volume: 39, Issue:4

    Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggre

2008
Network meta-analysis: simultaneous meta-analysis of common antiplatelet regimens after transient ischaemic attack or stroke.
    European heart journal, 2008, Volume: 29, Issue:9

    Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platelet Aggre

2008
Update on antiplatelet agents, including MATCH, CHARISMA, and ESPRIT.
    Current cardiology reports, 2008, Volume: 10, Issue:1

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Dipyridamole; Female; Humans; Ischemi

2008
Current therapy of cerebrovascular disease.
    The Journal of the Arkansas Medical Society, 1984, Volume: 80, Issue:11

    Topics: Adult; Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Female; Humans; Ische

1984
Therapeutical aspects of cerebrovascular disease.
    European neurology, 1983, Volume: 22 Suppl 1

    Topics: Aspirin; Blood Coagulation; Cerebrovascular Disorders; Clofibrate; Dipyridamole; Erythrocyte Aggrega

1983
Platelet inhibitors for TIAs. A review of prospective drug trial results.
    Postgraduate medicine, 1984, Volume: 75, Issue:5

    Topics: Aged; Aspirin; Clofibrate; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ischemic Attack,

1984
Therapy of ischemic cerebral vascular disease due to atherothrombosis. (2).
    The New England journal of medicine, 1984, Jul-12, Volume: 311, Issue:2

    Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Auscultation; Basilar Artery; Blood Platelets;

1984
Platelets, carotids, and coronaries. Critique on antithrombotic role of antiplatelet agents, exercise, and certain diets.
    The American journal of medicine, 1984, Volume: 77, Issue:3

    Topics: Angina Pectoris; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Carotid Artery Thrombosi

1984
Antiplatelet drugs in secondary prevention of stroke.
    International journal of clinical practice, 1998, Volume: 52, Issue:2

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Huma

1998
[Transient ischemic attacks and prolonged reversible ischemic neurologic deficit. Diagnosis, differential diagnosis and treatment].
    Praxis, 2000, Mar-23, Volume: 89, Issue:13

    Topics: Aspirin; Brain Ischemia; Cerebral Infarction; Diagnosis, Differential; Dipyridamole; Endarterectomy,

2000
Update on antiplatelet therapy for stroke prevention.
    Archives of internal medicine, 2000, Jun-12, Volume: 160, Issue:11

    Topics: Aspirin; Clinical Trials as Topic; Delayed-Action Preparations; Dipyridamole; Dose-Response Relation

2000
Prevention of ischaemic stroke--antiplatelets.
    British medical bulletin, 2000, Volume: 56, Issue:2

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Humans; Ischemic Attack, Transient; Pl

2000
Stroke prevention: antiplatelet and antithrombolytic therapy.
    Haemostasis, 2000, Volume: 30 Suppl 3

    Topics: Anticoagulants; Aspirin; Brain Damage, Chronic; Carotid Stenosis; Clinical Trials as Topic; Clopidog

2000
[Pharma-clinics. The drug of the month. Dipyridamole-acetylsalicylic acid combination (Aggrenox)].
    Revue medicale de Liege, 2000, Volume: 55, Issue:10

    Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Dipyridamole; Drug Combinations; Humans; Ischemic A

2000
Analysis of trials evaluating combinations of acetylsalicylic acid and dipyridamole in the secondary prevention of stroke.
    Clinical therapeutics, 2001, Volume: 23, Issue:9

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; Female; Humans; I

2001
Dipyridamole may be used safely in patients with ischaemic heart disease.
    International journal of clinical practice, 2002, Volume: 56, Issue:2

    Topics: Dipyridamole; Humans; Ischemic Attack, Transient; Myocardial Ischemia; Randomized Controlled Trials

2002
Platelet inhibitors in the treatment of thrombosis.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1978, Volume: 1, Issue:3-4

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof

1978
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (first of three parts).
    The New England journal of medicine, 1975, Dec-04, Volume: 293, Issue:23

    Topics: Animals; Antidepressive Agents, Tricyclic; Aspirin; Blindness; Blood Platelets; Cerebrovascular Diso

1975
Aspirin in transient ischemic attacks and minor stroke: a meta-analysis.
    Family practice research journal, 1991, Volume: 11, Issue:2

    Topics: Adult; Aspirin; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; Female; Humans;

1991
[Study Group: "Evaluation of the efficacy of therapeutic treatments in cerebrovascular diseases"].
    Epidemiologia e prevenzione, 1990, Volume: 12, Issue:43

    Topics: Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Female;

1990
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986
The management of TIAs in 1986.
    South Dakota journal of medicine, 1986, Volume: 39, Issue:7

    Topics: Arterial Occlusive Diseases; Aspirin; Carotid Artery Diseases; Cerebrovascular Disorders; Dipyridamo

1986
Aspirin and other platelet-aggregation inhibiting drugs.
    The Medical journal of Australia, 1985, Jan-07, Volume: 142, Issue:1

    Topics: Aspirin; Blood Platelets; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Female; Heart Valv

1985
Clinical aspects of antiplatelet therapy.
    Seminars in hematology, 1985, Volume: 22, Issue:2

    Topics: Angina Pectoris; Aspirin; Blood Coagulation Disorders; Clinical Trials as Topic; Dipyridamole; Femal

1985

Trials

52 trials available for dipyridamole and Ischemic Attack, Transient

ArticleYear
Effects of Dose Titration on Dipyridamole-Induced Headache: A Randomized, Double-Blind Clinical Trial.
    Cerebrovascular diseases (Basel, Switzerland), 2022, Volume: 51, Issue:4

    Topics: Aspirin; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Headache; Humans; Ischemic At

2022
Bleeding with intensive versus guideline antiplatelet therapy in acute cerebral ischaemia.
    Scientific reports, 2023, 07-20, Volume: 13, Issue:1

    Topics: Acute Disease; Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female

2023
Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.
    Lancet (London, England), 2018, 03-03, Volume: 391, Issue:10123

    Topics: Acute Disease; Aged; Aspirin; Brain Ischemia; Clopidogrel; Denmark; Dipyridamole; Drug Therapy, Comb

2018
RApid Primary care Initiation of Drug treatment for Transient Ischaemic Attack (RAPID-TIA): study protocol for a pilot randomised controlled trial.
    Trials, 2013, Jul-02, Volume: 14

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Agents; Clinical Protocols; Dipyridamole; Drug Admi

2013
The effect of a slower than standard dose escalation scheme for dipyridamole on headaches in secondary prevention therapy of strokes: a randomized, open-label trial (DOSE).
    Cerebrovascular diseases (Basel, Switzerland), 2014, Volume: 37, Issue:4

    Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Headache; Humans; Ischemic Attack, Transie

2014
A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility.
    PloS one, 2008, Aug-06, Volume: 3, Issue:8

    Topics: Aged; Aspirin; Blood Pressure; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Drug Tolerance;

2008
Dipyridamole-associated headache in stroke patients--interindividual differences?
    European neurology, 2009, Volume: 62, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Dipyridamole; Drug Therapy, Combination; Femal

2009
Early treatment with aspirin plus extended-release dipyridamole for transient ischaemic attack or ischaemic stroke within 24 h of symptom onset (EARLY trial): a randomised, open-label, blinded-endpoint trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspirin; Aspirin, Dipyridamole Drug Combinatio

2010
Enhanced ex vivo inhibition of platelet function following addition of dipyridamole to aspirin after transient ischaemic attack or ischaemic stroke: first results from the TRinity AntiPlatelet responsiveness (TrAP) study.
    British journal of haematology, 2011, Volume: 152, Issue:5

    Topics: Adult; Aged; Aspirin; Blood Platelets; Blood Specimen Collection; Dipyridamole; Drug Therapy, Combin

2011
Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial.
    Lancet (London, England), 2006, May-20, Volume: 367, Issue:9523

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyridamole; Drug Therapy, Combination; Fem

2006
Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial.
    Lancet (London, England), 2006, May-20, Volume: 367, Issue:9523

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyridamole; Drug Therapy, Combination; Fem

2006
Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial.
    Lancet (London, England), 2006, May-20, Volume: 367, Issue:9523

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyridamole; Drug Therapy, Combination; Fem

2006
Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial.
    Lancet (London, England), 2006, May-20, Volume: 367, Issue:9523

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyridamole; Drug Therapy, Combination; Fem

2006
Dose titration to reduce dipyridamole-related headache.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 22, Issue:4

    Topics: Aged; Aspirin; Dipyridamole; Drug Administration Schedule; Drug Therapy, Combination; Female; Headac

2006
Influence of antiplatelet therapy on cerebral micro-emboli after carotid endarterectomy using postoperative transcranial Doppler monitoring.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2007, Volume: 34, Issue:2

    Topics: Aged; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dextrans; Dipyri

2007
Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:3

    Topics: Age Factors; Aged; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel

2008
Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-b
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adult; Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Biomarkers; Clopidogrel; Diabetes Mell

2008
A perspective on platelet-suppressant drug treatment in coronary artery and cerebrovascular disease.
    Circulation, 1980, Volume: 62, Issue:6 Pt 2

    Topics: Adrenergic beta-Antagonists; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascula

1980
Randomised trial of pentoxifylline versus acetylsalicylic acid plus dipyridamole in preventing transient ischaemic attacks.
    Lancet (London, England), 1981, May-02, Volume: 1, Issue:8227

    Topics: Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Female; Follow-Up Studie

1981
[Role of antiplatelet agents in the prevention of cerebral ischemic accidents].
    Journal des maladies vasculaires, 1983, Volume: 8, Issue:1

    Topics: Adult; Aged; Anticoagulants; Arteriosclerosis; Aspirin; Blood Platelets; Clinical Trials as Topic; C

1983
A randomized clinical trial of pentoxifylline and antiaggregants in recent transient ischemic attacks (TIA). A one year follow-up.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Dipyridamole; Female; Follow-Up Studies; Humans; Isc

1981
[Prevention of recurrences of cerebral ischemic vascular accidents by platelet antiaggregants. Results of a 3-year controlled therapeutic trial].
    Revue neurologique, 1982, Volume: 138, Issue:5

    Topics: Aspirin; Clinical Trials as Topic; Dihydroergotoxine; Dipyridamole; Humans; Ischemic Attack, Transie

1982
Summary of ongoing clinical trials of platelet-active drugs in cardiovascular disease.
    Circulation, 1980, Volume: 62, Issue:6 Pt 2

    Topics: Adult; Aged; Angina Pectoris; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials a

1980
[anti-platelet therapy or anti-coagulants as prevention in transient ischemic attacks and reversible ischemic stroke].
    Lakartidningen, 1980, Dec-24, Volume: 77, Issue:52

    Topics: Aged; Anticoagulants; Aspirin; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Drug The

1980
["A.I.C.L.A." controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia. Part I: Protocol (author's transl)].
    Revue neurologique, 1981, Volume: 137, Issue:5

    Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Humans;

1981
Antiplatelet treatment in elderly people with transient ischaemic attacks or ischaemic strokes.
    BMJ (Clinical research ed.), 1995, Jan-07, Volume: 310, Issue:6971

    Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Cerebrovascular Disorders; Dipyridamole; Double-Blind

1995
Antiplatelet therapy is effective in primary prevention of myocardial infarction in patients with a previous cerebrovascular ischemic event.
    Archives of neurology, 1993, Volume: 50, Issue:7

    Topics: Aged; Aspirin; Cerebral Infarction; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ischemi

1993
European Stroke Prevention Study (ESPS): antithrombotic therapy is also effective in the elderly.
    Acta neurologica Scandinavica, 1993, Volume: 87, Issue:2

    Topics: Actuarial Analysis; Aged; Aspirin; Cause of Death; Cerebral Infarction; Cerebrovascular Disorders; D

1993
European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke.
    Journal of the neurological sciences, 1996, Volume: 143, Issue:1-2

    Topics: Adult; Aged; Aspirin; Cerebrovascular Disorders; Demography; Dipyridamole; Double-Blind Method; Fema

1996
Up to date review of the secondary preventive measures for recurrent ischaemic stroke and transient ischaemic episodes.
    Scottish medical journal, 1998, Volume: 43, Issue:1

    Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; Hu

1998
Risk factors and antiplatelet therapy in TIA and stroke patients.
    Journal of the neurological sciences, 1998, Feb-05, Volume: 154, Issue:2

    Topics: Aspirin; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Eu

1998
Efficacy of antiplatelet treatment in hypertensive patients with TIA or stroke.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:2

    Topics: Aspirin; Blood Pressure; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Drug Therapy,

1998
Secondary stroke prevention with low-dose aspirin, sustained release dipyridamole alone and in combination. ESPS Investigators. European Stroke Prevention Study.
    Thrombosis research, 1998, Sep-15, Volume: 92, Issue:1 Suppl 1

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Delayed-Action Preparations; Dipyridamole; Disease-Free Su

1998
Second European Stroke Prevention Study: antiplatelet therapy is effective regardless of age. ESPS2 Working Group.
    Acta neurologica Scandinavica, 1999, Volume: 99, Issue:1

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aspirin; Brain Ischemia; Cerebrovascular Disorders;

1999
[Prevention of vascular complications after cerebral ischemia of arterial origin. European Stroke and Australian Stroke Prevention in Reversible Ischemia Trial (ESPRIT): moderated coagulation, aspirin-dipyridamole combination or aspirin alone?].
    La Revue de medecine interne, 1999, Volume: 20, Issue:5

    Topics: Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; Humans;

1999
Cardiac safety in the European Stroke Prevention Study 2 (ESPS2).
    International journal of clinical practice, 2001, Volume: 55, Issue:3

    Topics: Angina Pectoris; Aspirin; Dipyridamole; Humans; Ischemic Attack, Transient; Longitudinal Studies; My

2001
[Does early high dosage dipyridamole in prevention of secondary stroke induce cardiac events?].
    Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:5

    Topics: Administration, Oral; Angina Pectoris; Aspirin; Cause of Death; Cerebral Infarction; Delayed-Action

2001
Guidelines for the management of transient ischemic attacks.
    Mayo Clinic proceedings, 1978, Volume: 53, Issue:10

    Topics: Anticoagulants; Aspirin; Blood Platelets; Carotid Arteries; Clinical Trials as Topic; Dipyridamole;

1978
Platelet inhibitors in the treatment of thrombosis.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1978, Volume: 1, Issue:3-4

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof

1978
An investigation of the effect on platelet function of acetylsalicylic acid, dipyridamole and the two drugs in combination in patients with transient attacks of ischaemia.
    The Journal of international medical research, 1979, Volume: 7, Issue:6

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Female; Hum

1979
Does aspirin prevent stroke?
    The Practitioner, 1979, Volume: 223, Issue:1337

    Topics: Anticoagulants; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Dipyr

1979
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (first of three parts).
    The New England journal of medicine, 1975, Dec-04, Volume: 293, Issue:23

    Topics: Animals; Antidepressive Agents, Tricyclic; Aspirin; Blindness; Blood Platelets; Cerebrovascular Diso

1975
Antiplatelet therapy is effective in the prevention of stroke or death in women: subgroup analysis of the European Stroke Prevention Study (ESPS).
    Acta neurologica Scandinavica, 1991, Volume: 84, Issue:4

    Topics: Aspirin; Cause of Death; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; Female;

1991
The European Stroke Prevention Study: results according to sex.
    Neurology, 1991, Volume: 41, Issue:8

    Topics: Aspirin; Cerebrovascular Disorders; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Male;

1991
The European Stroke Prevention Study (ESPS): results by arterial distribution.
    Annals of neurology, 1991, Volume: 29, Issue:6

    Topics: Aspirin; Carotid Arteries; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Drug Therap

1991
[Study Group: "Evaluation of the efficacy of therapeutic treatments in cerebrovascular diseases"].
    Epidemiologia e prevenzione, 1990, Volume: 12, Issue:43

    Topics: Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Female;

1990
European Stroke Prevention Study. ESPS Group.
    Stroke, 1990, Volume: 21, Issue:8

    Topics: Age Factors; Aspirin; Brain Ischemia; Carotid Artery Diseases; Cerebrovascular Disorders; Clinical T

1990
Comparative study of pentoxifylline vs antiaggregants in patients with transient ischaemic attacks.
    Acta neurologica Scandinavica. Supplementum, 1989, Volume: 127

    Topics: Aged; Aspirin; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Pentoxif

1989
Antiplatelet agents in the secondary prevention of stroke: meta-analysis of the randomized control trials.
    Stroke, 1988, Volume: 19, Issue:4

    Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Dipyridamole; Drug Combinations; Human

1988
Clinical trials evaluating platelet-modifying drugs in patients with atherosclerotic cardiovascular disease and thrombosis.
    Circulation, 1986, Volume: 73, Issue:2

    Topics: Anticoagulants; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cardiovascular Diseases; Clinical

1986
[Randomized clinical study of the efficacy of buflomedil in the prevention of recurrence of cerebral ischemia in comparison with anti-platelet aggregation agents].
    La Clinica terapeutica, 1986, Mar-15, Volume: 116, Issue:5

    Topics: Aspirin; Clinical Trials as Topic; Dipyridamole; Humans; Ischemic Attack, Transient; Pyrrolidines; R

1986
Preventive treatment of cerebral transient ischemia: comparative randomized trial of pentoxifylline versus conventional antiaggregants.
    European neurology, 1985, Volume: 24, Issue:1

    Topics: Aged; Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Combinations; Female; Humans; Ischemic A

1985
Clinical aspects of antiplatelet therapy.
    Seminars in hematology, 1985, Volume: 22, Issue:2

    Topics: Angina Pectoris; Aspirin; Blood Coagulation Disorders; Clinical Trials as Topic; Dipyridamole; Femal

1985
Dipyridamole and postoperative ischemic deficits in aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 1985, Volume: 63, Issue:5

    Topics: Blood Platelets; Clinical Trials as Topic; Dipyridamole; Humans; Intracranial Aneurysm; Ischemic Att

1985
Controlled trial of dipyridamole in cerebral vascular disease.
    British medical journal, 1969, Mar-08, Volume: 1, Issue:5644

    Topics: Cerebrovascular Disorders; Clinical Trials as Topic; Dipyridamole; Female; Headache; Humans; Ischemi

1969

Other Studies

94 other studies available for dipyridamole and Ischemic Attack, Transient

ArticleYear
Assessment of on-treatment platelet reactivity at high and low shear stress and platelet activation status after the addition of dipyridamole to aspirin in the early and late phases after TIA and ischaemic stroke.
    Journal of the neurological sciences, 2022, 10-15, Volume: 441

    Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Brain Ischemia; Dipyridamole; Humans; Ischemic Atta

2022
Balancing Benefits and Risks of Long-Term Antiplatelet Therapy in Noncardioembolic Transient Ischemic Attack or Stroke.
    Stroke, 2021, Volume: 52, Issue:10

    Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Humans; Intracranial Hemorrhages; Isc

2021
Oral Dipyridamole-Associated Circulatory Collapse.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:12

    Topics: Administration, Oral; Aged; Delayed-Action Preparations; Dipyridamole; Humans; Ischemic Attack, Tran

2018
Implications of aspirin biochemistry in the pathobiology of ischemic cerebrovascular disease.
    Journal of the neurological sciences, 2014, Jan-15, Volume: 336, Issue:1-2

    Topics: Aspirin; Dipyridamole; Female; Fibrinolytic Agents; Humans; Ischemic Attack, Transient; Male; Random

2014
Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan.
    Advances in therapy, 2014, Volume: 31, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Cilostazol; Dipyridamole

2014
Longitudinal assessment of von Willebrand factor antigen and von Willebrand factor propeptide in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
    Journal of neurology, 2014, Volume: 261, Issue:7

    Topics: Adult; Aged; Aspirin; Clopidogrel; Dipyridamole; Enzyme-Linked Immunosorbent Assay; Female; Humans;

2014
Secondary stroke prevention with antiplatelet drugs: have we reached the ceiling?
    International journal of stroke : official journal of the International Stroke Society, 2006, Volume: 1, Issue:1

    Topics: Age Factors; Aged; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Combi

2006
Is the finding of the PROFESS study consistent with predictions of network meta-analysis?
    European heart journal, 2008, Volume: 29, Issue:20

    Topics: Aspirin; Bayes Theorem; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient;

2008
The use of aspirin and dipyridamole in the treatment of acute ischaemic stroke/transient ischaemic attack: an audit-based discussion.
    Clinical medicine (London, England), 2009, Volume: 9, Issue:2

    Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Medical Audit;

2009
[Guidelines recommend aspirin/dipyridamole retard in high recurrence risk. Well protected from the second stroke].
    MMW Fortschritte der Medizin, 2009, Jul-23, Volume: 151, Issue:30-33

    Topics: Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Cerebral Infarction; Clinical Trials as Topic

2009
Medical treatment of patients with intracranial atherosclerotic disease.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2009, Volume: 19 Suppl 1

    Topics: Anticoagulants; Aspirin; Atherosclerosis; Brain Ischemia; Cilostazol; Clopidogrel; Dipyridamole; Emb

2009
TIAs - management in general practice.
    Australian family physician, 2010, Volume: 39, Issue:11

    Topics: Anticoagulants; Antihypertensive Agents; Aspirin; Atorvastatin; Clopidogrel; Dipyridamole; Dopamine

2010
Antiplatelet therapy for transient ischemic attack.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Clopidogrel; Cognition Disorders;

2012
Prevalence of ex vivo high on-treatment platelet reactivity on antiplatelet therapy after transient ischemic attack or ischemic stroke on the PFA-100(®) and VerifyNow(®).
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2013, Volume: 22, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Aspirin, Dipyridamole Drug Combination; Blood Platelets; Br

2013
“ Cerebrovascular stressing”: dipyridamole-induced S100B elevation predicts ischemic cerebrovascular events.
    Clinical chemistry and laboratory medicine, 2013, Volume: 51, Issue:4

    Topics: Biomarkers; Coronary Artery Disease; Dipyridamole; Female; Follow-Up Studies; Humans; Ischemic Attac

2013
Longitudinal assessment of thrombin generation potential in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
    Journal of neurology, 2013, Volume: 260, Issue:2

    Topics: Adult; Aged; Aspirin; Clopidogrel; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Longitu

2013
[Secondary prevention after stroke. 2 platelet inhibitors are better than one].
    MMW Fortschritte der Medizin, 2002, May-09, Volume: 144, Issue:19

    Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Cerebral Infarction; Clinical Trials as Topic; Dipy

2002
Aspirin therapy should be first-line treatment in secondary prevention of stroke--against.
    Stroke, 2002, Volume: 33, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Drug

2002
[PRoFESS study presented. Change in secondary prevention].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Aspirin, Dipyridamole Drug Combination; Benzimida

2003
[Secondary prevention of ischemic insult and transient cerebral ischemia. Is ASS alone enough?].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Aspirin; Controlled Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Humans; Ische

2003
[Secondary prevention after stroke. Doubled performs better].
    MMW Fortschritte der Medizin, 2003, Nov-13, Volume: 145, Issue:46

    Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Controlled Clinical Trials as Topic; Dipyridamole;

2003
[After stroke or TIA. Double protection by second platelet inhibitor].
    MMW Fortschritte der Medizin, 2003, Dec-11, Volume: 145, Issue:50

    Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Clinical Trials as Topic; Delayed-Action Preparatio

2003
[For which patient ASS, clopidogrel or dipyridamole? (interview by Dr. Med. Dirk Einecke)].
    MMW Fortschritte der Medizin, 2004, Jun-10, Volume: 146, Issue:24

    Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Com

2004
[Summary of the practice guideline 'TIA' (first revision) from the Dutch College of General Practitioners].
    Nederlands tijdschrift voor geneeskunde, 2005, Feb-12, Volume: 149, Issue:7

    Topics: Aspirin; Dipyridamole; Family Practice; Female; Fibrinolytic Agents; Humans; Ischemic Attack, Transi

2005
[Summary of the practice guideline 'TIA' (first revision) from the Dutch College of General Practitioners].
    Nederlands tijdschrift voor geneeskunde, 2005, May-21, Volume: 149, Issue:21

    Topics: Aspirin; Dipyridamole; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Ischemic Attack, Transi

2005
Use of dipyridamole in patients with recent stroke or TIA.
    American family physician, 2005, Aug-01, Volume: 72, Issue:3

    Topics: Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack,

2005
Secondary stroke prevention with antiplatelet therapy with emphasis on the cardiac patient: a neurologist's view.
    Journal of the American College of Cardiology, 2005, Sep-06, Volume: 46, Issue:5

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Drug Ther

2005
Platelet emboli and ischemia in rabbit's brain caused by ADP or arachidonic acid and the protective effect of ASA and dipyridamole.
    Biochemistry and experimental biology, 1977, Volume: 13, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Dipyridamole; Intracranial Embolism; Isch

1977
[New DGN-/DSG guidelines].
    Krankenpflege Journal, 2005, Volume: 43, Issue:7-10

    Topics: Adult; Aspirin; Aspirin, Dipyridamole Drug Combination; Cerebral Infarction; Clinical Trials as Topi

2005
[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed].
    Nederlands tijdschrift voor geneeskunde, 2006, Aug-19, Volume: 150, Issue:33

    Topics: Anticoagulants; Aspirin; Cerebral Infarction; Dipyridamole; Drug Therapy, Combination; Humans; Ische

2006
[Prevention of vascular events after transient ischemic attack or cerebral infarct].
    La Revue du praticien, 2006, Sep-15, Volume: 56, Issue:13

    Topics: Angioplasty, Balloon; Anticoagulants; Aspirin; Cerebral Infarction; Clopidogrel; Dipyridamole; Drug

2006
[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed].
    Nederlands tijdschrift voor geneeskunde, 2006, Dec-02, Volume: 150, Issue:48

    Topics: Aspirin; Cerebral Infarction; Dipyridamole; Headache; Humans; Ischemic Attack, Transient; Platelet A

2006
[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed].
    Nederlands tijdschrift voor geneeskunde, 2006, Dec-02, Volume: 150, Issue:48

    Topics: Aspirin; Cerebral Infarction; Dipyridamole; Evidence-Based Medicine; Financial Support; Humans; Isch

2006
Influence of antiplatelet therapy on cerebral micro-emboli after carotid endarterectomy using postoperative transcranial Doppler monitoring.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2007, Volume: 34, Issue:2

    Topics: Aged; Anticoagulants; Aspirin; Aspirin, Dipyridamole Drug Combination; Clopidogrel; Dextrans; Dipyri

2007
Musical hallucinations induced by drugs.
    International psychogeriatrics, 2007, Volume: 19, Issue:6

    Topics: Aged, 80 and over; Diagnosis, Differential; Dipyridamole; Female; Hallucinations; Humans; Ischemic A

2007
[Antithrombotic therapy in ischemic stroke and transient ischemic attack].
    Ugeskrift for laeger, 2007, Oct-01, Volume: 169, Issue:40

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Fibrinolytic Agents;

2007
Antiplatelet agents for stroke prevention following transient ischemic attack.
    Southern medical journal, 2008, Volume: 101, Issue:1

    Topics: Angioplasty, Balloon; Aspirin; Carotid Artery Diseases; Clopidogrel; Dipyridamole; Drug Therapy, Com

2008
Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack.
    Stroke, 2008, Volume: 39, Issue:5

    Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Combinations; Dru

2008
Trends in usage of alternative antiplatelet therapy after stroke and transient ischemic attack.
    Stroke, 2008, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Prescrip

2008
[Antiplatelet treatment after acute and chronic ischemic heart and brain events is insufficient according to recommendations].
    Ugeskrift for laeger, 2008, Mar-31, Volume: 170, Issue:14

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Aspirin;

2008
Treatment of cerebral ischemia.
    Comprehensive therapy, 1981, Volume: 7, Issue:4

    Topics: Aspirin; Brain Ischemia; Carotid Arteries; Dicumarol; Dipyridamole; Endarterectomy; Heart Murmurs; H

1981
Prognostic value of beta-thromboglobulin in patients with transient cerebral ischaemia.
    Lancet (London, England), 1983, Aug-27, Volume: 2, Issue:8348

    Topics: Adult; Age Factors; Aged; Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Platelets; Cerebrovas

1983
Plasma thromboglobulin and platelet aggregation index in transient ischaemic attack: effect of aspirin and dipyridamole therapy.
    International journal of clinical pharmacology research, 1983, Volume: 3, Issue:5

    Topics: Adult; Aged; Aspirin; Beta-Globulins; beta-Thromboglobulin; Dipyridamole; Humans; Ischemic Attack, T

1983
Inhibition by dipyridamole of cerebral vasospasm induced in vitro by whole blood.
    Journal of neurosurgery, 1983, Volume: 58, Issue:3

    Topics: Animals; Blood; Cyclic AMP; Dipyridamole; Epoprostenol; Female; In Vitro Techniques; Ischemic Attack

1983
Surgical management of the occluded carotid artery.
    Surgery, 1984, Volume: 96, Issue:5

    Topics: Adult; Aged; Arterial Occlusive Diseases; Aspirin; Carotid Arteries; Carotid Artery Diseases; Cerebr

1984
Atherosclerosis and cerebral ischemic attacks: intakes of cerebrography with xenon133 inhaled and platelet tests in the diagnosis, clinical and therapeutic monitoring; the preventive role of dipyridamole.
    Angiology, 1984, Volume: 35, Issue:11

    Topics: Adult; Aerosols; Aged; Arteriosclerosis; Dipyridamole; Female; Humans; Ischemic Attack, Transient; M

1984
The lame brain at the crossroads: which therapeutic road?
    The New Zealand medical journal, 1984, Apr-25, Volume: 97, Issue:754

    Topics: Aged; Aspirin; Carotid Artery Diseases; Cerebral Infarction; Cerebrovascular Disorders; Dipyridamole

1984
Transient ischemic attacks. Strategies for minimizing stroke risk.
    Postgraduate medicine, 1984, Volume: 75, Issue:6

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Dipyridamole; Humans; Ischemic Attack, Transient; Middle A

1984
Management of transient cerebral ischaemic attacks by hospital doctors in Scotland.
    Journal of the Royal College of Physicians of London, 1983, Volume: 17, Issue:3

    Topics: Anticoagulants; Aspirin; Carotid Arteries; Cerebrovascular Disorders; Dipyridamole; Female; Humans;

1983
Platelet aggregation in focal cerebral ischemia -a clinical study.
    Acta neurologica Scandinavica, 1982, Volume: 65, Issue:3

    Topics: Adult; Aged; Aspirin; Brain Ischemia; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Male

1982
[Platelet function inhibition and anticoagulation in coronary, cerebral and peripheral arterial occlusive disease. 2. Secondary prevention].
    Fortschritte der Medizin, 1982, May-13, Volume: 100, Issue:18

    Topics: Anticoagulants; Aspirin; Brain Ischemia; Dipyridamole; Female; Humans; Ischemic Attack, Transient; M

1982
Blood platelets and neurological dysfunction.
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:5

    Topics: Aspirin; Blood Platelets; Child; Dipyridamole; Humans; Ischemic Attack, Transient; Migraine Disorder

1982
[Preventive drug therapy of transient cerebral ischemic attacks].
    Ugeskrift for laeger, 1982, Aug-09, Volume: 144, Issue:32

    Topics: Anticoagulants; Aspirin; Dipyridamole; Humans; Ischemic Attack, Transient; Platelet Aggregation; Sul

1982
Circulating platelet aggregates: a chronic platelet activation in patients with transient ischaemic attacks.
    Italian journal of neurological sciences, 1980, Volume: 1, Issue:3

    Topics: Aspirin; Cerebral Angiography; Dipyridamole; Humans; Intracranial Arteriosclerosis; Ischemic Attack,

1980
For your stroke-prone patients: a guide to drug treatment.
    Geriatrics, 1980, Volume: 35, Issue:2

    Topics: Aged; Antihypertensive Agents; Aspirin; Brain Diseases; Cerebral Angiography; Cerebrovascular Disord

1980
Antiplatelet drugs after myocardial infarction.
    The Medical letter on drugs and therapeutics, 1980, Mar-21, Volume: 22, Issue:6

    Topics: Aspirin; Dipyridamole; Humans; Ischemic Attack, Transient; Myocardial Infarction; Platelet Aggregati

1980
Safety of dipyridamole testing in patients with cerebrovascular disease.
    The American journal of cardiology, 1995, Mar-01, Volume: 75, Issue:7

    Topics: Aged; Cerebrovascular Disorders; Dipyridamole; Female; Hemodynamics; Humans; Ischemic Attack, Transi

1995
Secondary prevention of stroke--new trials.
    Scottish medical journal, 1998, Volume: 43, Issue:1

    Topics: Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Delayed-Action Preparations; Dipyridamole; Dr

1998
Supplement to the AHA guidelines for the management of transient ischemic attacks.
    Stroke, 2000, Volume: 31, Issue:4

    Topics: Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack,

2000
Cost-effectiveness of new antiplatelet regimens used as secondary prevention of stroke or transient ischemic attack.
    Archives of internal medicine, 2000, Oct-09, Volume: 160, Issue:18

    Topics: Aged; Aspirin; Clopidogrel; Cost-Benefit Analysis; Decision Trees; Dipyridamole; Drug Therapy, Combi

2000
Alert to physicians: possible interaction of aggrenox and adenosine.
    Journal of the American College of Cardiology, 2000, Volume: 36, Issue:4

    Topics: Adenosine; Aspirin; Aspirin, Dipyridamole Drug Combination; Brain Ischemia; Delayed-Action Preparati

2000
Transient ischemic attacks after dipyridamole-aspirin therapy.
    Journal of neurology, 2000, Volume: 247, Issue:10

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyridamole; Drug The

2000
[Dipyridamole test in the early detection of cerebrovascular disorders?].
    Orvosi hetilap, 2000, Dec-10, Volume: 141, Issue:50

    Topics: Cerebrovascular Circulation; Diagnosis, Differential; Dipyridamole; Female; Humans; Ischemic Attack,

2000
Current strategies of secondary prevention after a cerebrovascular event: the Vienna stroke registry.
    Stroke, 2001, Dec-01, Volume: 32, Issue:12

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation;

2001
[Antiaggregant therapy in cerebrovascular insufficiency in the aged].
    La Clinica terapeutica, 1979, Jan-15, Volume: 88, Issue:1

    Topics: Aged; Aspirin; Blood Platelet Disorders; Dipyridamole; Drug Evaluation; Female; Humans; Ischemic Att

1979
Platelet activation in acute cerebral ischaemia. Serial measurements of platelet function in cerebrovascular disease.
    Lancet (London, England), 1977, Apr-16, Volume: 1, Issue:8016

    Topics: Acute Disease; Adenosine Diphosphate; Aged; Aspirin; Blood Cell Count; Blood Platelets; Cerebrovascu

1977
Aspirin dose in prevention of transient ischaemic attacks.
    Lancet (London, England), 1979, Apr-14, Volume: 1, Issue:8120

    Topics: Aged; Anticoagulants; Aspirin; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Tra

1979
Treating thromboembolic disease.
    Geriatrics, 1977, Volume: 32, Issue:10

    Topics: Anticoagulants; Aspirin; Coronary Artery Bypass; Dipyridamole; Fibrinolytic Agents; Heart Valve Pros

1977
[Therapy with anticoagulants and platelet aggregation inhibitors in extracranial vascular stenoses and occlusions].
    Der Internist, 1979, Volume: 20, Issue:11

    Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cerebral Infarction; Cerebrovascular Disorders

1979
Transient ischemic attacks due to increased platelet aggregation and adhesiveness. Ultrastructural and functional correlation.
    Journal of neurosurgery, 1979, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Dipy

1979
[Action mechanism and clinical indications for thrombocyte aggregation inhibitors].
    Schweizerische medizinische Wochenschrift, 1979, Mar-10, Volume: 109, Issue:10

    Topics: Anticoagulants; Aspirin; Coronary Disease; Dipyridamole; Humans; Ischemic Attack, Transient; Myocard

1979
[Antiplatelet drugs (author's transl)].
    Anesthesie, analgesie, reanimation, 1979, Volume: 36, Issue:7-8

    Topics: Aspirin; Blood Platelets; Clofibrate; Dipyridamole; Female; Humans; Hydroxychloroquine; Ischemic Att

1979
[Transient cerebral ischemic attacks. Treatment program and comparison between anticoagulants and thrombocyte aggregation repressors].
    Lakartidningen, 1979, Aug-22, Volume: 76, Issue:34

    Topics: Aged; Anticoagulants; Aspirin; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Male; Time

1979
TIA, stroke, and mitral valve prolapse.
    Neurology, 1979, Volume: 29, Issue:6

    Topics: Adult; Aged; Aspirin; Carotid Artery Thrombosis; Cerebrovascular Disorders; Dipyridamole; Echocardio

1979
Transient ischaemic attacks and increased platelet aggregability associated with oral contraceptives. Treatment with dipyridamole and aspirin.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:1

    Topics: Adult; Aspirin; Contraceptives, Oral; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Plat

1977
Dipyridamole for vertebrobasilar insufficiency.
    The Medical journal of Australia, 1977, Feb-12, Volume: 1, Issue:7

    Topics: Basilar Artery; Dipyridamole; Humans; Ischemic Attack, Transient; Male; Middle Aged; Vertebral Arter

1977
Effect of drugs of platelets and complications of vascular disease.
    Advances in experimental medicine and biology, 1977, Volume: 82

    Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation; Blood Platelets; Clofibrate; Coronary Disease;

1977
Spontaneous platelet aggregation in arterial insufficiency: mechanisms and implications.
    Thrombosis and haemostasis, 1976, Jun-30, Volume: 35, Issue:3

    Topics: Adenosine; Adult; Aged; Angina Pectoris; Apyrase; Arterial Occlusive Diseases; Aspirin; Coronary Dis

1976
Letter: Medical management of transient ischaemic attacks.
    British medical journal, 1975, Mar-29, Volume: 1, Issue:5960

    Topics: Anti-Inflammatory Agents; Anticoagulants; Aspirin; Dipyridamole; Humans; Ischemic Attack, Transient;

1975
The pyrimido-pyrimidine derivative RA-642 protects from brain injury in a combined model of permanent focal ischemia and global ischemia reperfusion.
    Brain research, 1992, Dec-04, Volume: 597, Issue:2

    Topics: Animals; Brain; Dipyridamole; Disease Models, Animal; Ischemic Attack, Transient; Lipid Peroxidation

1992
[Carotid endarterectomy for prevention of stroke: comparison of surgical and conservative therapy].
    Der Nervenarzt, 1991, Volume: 62, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral

1991
Influence of antiplatelet drugs on beta tg and PF4 levels in patients with transient ischemic attacks.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 13

    Topics: Adult; Aspirin; Beta-Globulins; beta-Thromboglobulin; Dipyridamole; Female; Humans; Ischemic Attack,

1985
The role of antiplatelet drugs in carotid reconstructive surgery.
    Annals of surgery, 1985, Volume: 201, Issue:6

    Topics: Adult; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Dextrans; Dipyridamole; D

1985
Short-term outcome of medically treated patients with transient ischemic attacks, reversible ischemic neurologic deficits and strokes with minimum residuum.
    European neurology, 1985, Volume: 24, Issue:4

    Topics: Anticoagulants; Aspirin; Brain Ischemia; Dicumarol; Dipyridamole; Drug Therapy, Combination; Female;

1985
Sneddon's syndrome: an antiphospholipid antibody syndrome?
    Neurology, 1988, Volume: 38, Issue:5

    Topics: Antibodies; Aspirin; Blood Coagulation Factors; Cardiolipins; Cerebral Infarction; Dipyridamole; Fem

1988
[Prevention of the recurrence of episodes of cerebral ischemia. Therapeutic protocol].
    Minerva medica, 1988, Volume: 79, Issue:8

    Topics: Aged; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Isoindoles; Male; Middle Aged; Pheny

1988
Prevention of postoperative neurologic deficits after carotid endarterectomy. Is platelet inhibition beneficial?
    The American surgeon, 1987, Volume: 53, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carotid Artery Diseases; Cerebrovascular Disorders; Dipyrid

1987
Pharmacologic approach to ischemic stroke management.
    The Nursing clinics of North America, 1986, Volume: 21, Issue:2

    Topics: Aspirin; Blood Platelets; Cerebrovascular Disorders; Dipyridamole; Drug Interactions; Heparin; Human

1986
Spontaneous dissection of the carotid artery: an unusual cause of stroke in younger patients.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1987, Jan-01, Volume: 136, Issue:1

    Topics: Adult; Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Angiography; Cerebrovasc

1987
Enteric-coated acetylsalicylic acid plus dipyridamole compared with anticoagulants in the prevention of ischemic events in patients with transient ischemic attacks.
    Acta neurologica Scandinavica, 1985, Volume: 71, Issue:6

    Topics: Aged; Anticoagulants; Aspirin; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; F

1985
Effect of anticoagulants, vasodilators, and dipyridamole on postischemic cerebral vascular obstruction.
    The Journal of surgical research, 1972, Volume: 13, Issue:2

    Topics: Amino Alcohols; Animals; Anticoagulants; Bicarbonates; Cerebrovascular Disorders; Dipyridamole; Ethy

1972
[Platelet function disorders and ischemic cerebral accidents. Therapeutic prospects].
    Revue neurologique, 1972, Volume: 126, Issue:1

    Topics: Adult; Aspirin; Blood Coagulation Tests; Blood Platelet Disorders; Cerebrovascular Disorders; Dipyri

1972
[Neuropsychiatry in 1973].
    La Revue du praticien, 1973, Apr-21, Volume: 23, Issue:23

    Topics: Aspirin; Bipolar Disorder; Dipyridamole; Heart Diseases; Humans; Hydrocephalus; Hypoxia, Brain; Isch

1973
Address of the president-elect: the indication for various methods of treatment of occlusive cerebrovascular disease.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Anticoagulants; Aspirin; Blood Pressure; Cardiac Output; Carotid Arteries; Cerebral Angiography; Cer

1973