Page last updated: 2024-10-26

dipyridamole and Ischemia

dipyridamole has been researched along with Ischemia in 82 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Extended release dipyridamole (ERD) is widely used in patients after ischaemic stroke; however, the ability of this antithrombotic agent to be stored in different blood cells has never been explored in post-stroke patients."9.14Distribution of dipyridamole in blood components among post-stroke patients treated with extended release formulation. ( Atar, OD; Booze, C; Eisert, C; Hanley, D; Sabaeva, E; Serebruany, V, 2009)
"Headache is reported by about one third of patients using dipyridamole (DP) after stroke or TIA."9.11Dipyridamole and headache--a pilot study of initial dose titration. ( Husted, S; Lindgren, A; Staaf, G; Ziegler, B, 2004)
"32 patients (mean age 65 years, range 51-75 years) were included in this controlled, double blind study to evaluate the effect of dipyridamole in patients with intermittent claudication."9.07[Double-blind study of the effect of dipyridamole in patients with intermittent claudication]. ( Baumgartner, I; Bollinger, A; Schalch, I, 1992)
"A randomized, double-blind, placebo-controlled study was performed to investigate the effect of dipyridamole at a usual oral dose of 150 mg/day on 18 patients with angina pectoris and positive treadmill exercise electrocardiography."9.06Effect of dipyridamole at the usual oral dose on exercise-induced myocardial ischemia in stable angina pectoris. ( Horie, H; Ishikawa, K; Okada, M; Tsuya, T, 1990)
"Dipyridamole anti-platelet therapy has previously been suggested to ameliorate chronic tissue ischemia in healthy animals."7.77Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress. ( Bir, SC; Branch, BG; Greber, E; Kevil, CG; Pardue, S; Patel, RP; Pattillo, CB; Shen, X, 2011)
"Six patients with advanced arteriosclerosis obliterans in the lower extremities were subjected to an exercise test on a tread mill with and without dipyridamole treatment."7.66Lack of effect of ischemia and dipyridamole on prostacyclin production in arteriosclerosis obliterans. ( Kärkölä, P; Pokela, R; Viinikka, L; Ylikorkala, O, 1981)
" We have found that the beneficial effects of dipyridamole therapy are due to its ability to increase tissue nitric oxide bioavailability that corrects tissue redox imbalance."6.46Reperfusion of chronic tissue ischemia: nitrite and dipyridamole regulation of innate immune responses. ( Fang, K; Kevil, CG; Pattillo, CB; Terracciano, J, 2010)
"1 The effects of propranolol and practolol, at equivalent myocardial beta-adrenoceptor blocking doses, (as assessed by the degree of shift of isoprenaline dose-response curves) were investigated in anaesthetized greyhounds before and after acute coronary artery ligation."5.26Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction. ( Marshall, RJ; Parratt, JR, 1976)
"Extended release dipyridamole (ERD) is widely used in patients after ischaemic stroke; however, the ability of this antithrombotic agent to be stored in different blood cells has never been explored in post-stroke patients."5.14Distribution of dipyridamole in blood components among post-stroke patients treated with extended release formulation. ( Atar, OD; Booze, C; Eisert, C; Hanley, D; Sabaeva, E; Serebruany, V, 2009)
"Headache is reported by about one third of patients using dipyridamole (DP) after stroke or TIA."5.11Dipyridamole and headache--a pilot study of initial dose titration. ( Husted, S; Lindgren, A; Staaf, G; Ziegler, B, 2004)
"32 patients (mean age 65 years, range 51-75 years) were included in this controlled, double blind study to evaluate the effect of dipyridamole in patients with intermittent claudication."5.07[Double-blind study of the effect of dipyridamole in patients with intermittent claudication]. ( Baumgartner, I; Bollinger, A; Schalch, I, 1992)
"A randomized, double-blind, placebo-controlled study was performed to investigate the effect of dipyridamole at a usual oral dose of 150 mg/day on 18 patients with angina pectoris and positive treadmill exercise electrocardiography."5.06Effect of dipyridamole at the usual oral dose on exercise-induced myocardial ischemia in stable angina pectoris. ( Horie, H; Ishikawa, K; Okada, M; Tsuya, T, 1990)
"Dipyridamole anti-platelet therapy has previously been suggested to ameliorate chronic tissue ischemia in healthy animals."3.77Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress. ( Bir, SC; Branch, BG; Greber, E; Kevil, CG; Pardue, S; Patel, RP; Pattillo, CB; Shen, X, 2011)
"Exercise electrocardiography and pharmacological stress echocardiography (171 dipyridamole, 73 dobutamine) were performed in 244 women (age 60+/-10 years) with chest pain and known coronary artery disease."3.71The incremental prognostic value of pharmacological stress echo over exercise electrocardiography in women with chest pain of unknown origin. ( Azzarelli, A; Cortigiani, L; Dodi, C; Masini, M; Nannini, E; Olivotto, I, 2001)
"Prostacyclin, the stable prostacyclin analogue carbacyclin, the thromboxane synthetase inhibitor UK-38,485, and the phosphodiesterase inhibitor dipyridamole were tested on rabbit epigastric free flaps for their ability to improve flap survival after a period of ischemia."3.68Prostacyclin and prostanoid modifiers aid ischemic skin flap survival. ( Angus, JA; Coe, SA; Kawabata, H; Knight, KR; O'Brien, BM; Sakai, K, 1991)
" Twenty-nine studies were performed at control, 13 during ischemia, eight after reperfusion, 13 during dipyridamole-induced hyperemia, and two during alteration of cardiac workload."3.68Validation of [1-11C]acetate as a tracer for noninvasive assessment of oxidative metabolism with positron emission tomography in normal, ischemic, postischemic, and hyperemic canine myocardium. ( Armbrecht, JJ; Buxton, DB; Schelbert, HR, 1990)
"Six patients with advanced arteriosclerosis obliterans in the lower extremities were subjected to an exercise test on a tread mill with and without dipyridamole treatment."3.66Lack of effect of ischemia and dipyridamole on prostacyclin production in arteriosclerosis obliterans. ( Kärkölä, P; Pokela, R; Viinikka, L; Ylikorkala, O, 1981)
"Thirty-five patients with gangrene or pregangrene of the feed associated with palpable peripheral pulses have been treated with the platelet suppressive drugs aspirin and dipyridamole."3.66Gangrene of the toes with palpable peripheral pulses. ( Chatterjee, DK; Greaney, M; Morris-Jones, W; Preston, FE, 1981)
" We have found that the beneficial effects of dipyridamole therapy are due to its ability to increase tissue nitric oxide bioavailability that corrects tissue redox imbalance."2.46Reperfusion of chronic tissue ischemia: nitrite and dipyridamole regulation of innate immune responses. ( Fang, K; Kevil, CG; Pattillo, CB; Terracciano, J, 2010)
"Dipyridamole was first introduced as an antianginal, coronary vasodilator agent."2.38Dipyridamole-echocardiography test: historical background and physiologic basis. ( Picano, E, 1989)
"Dipyridamole treatment quickly restored ischaemic hindlimb blood flow, increased vascular density and cell proliferation, and enhanced collateral artery perfusion compared with control treatments."1.36Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway. ( Branch, B; Hood, J; Illum, S; Kevil, CG; Pardue, S; Patel, RP; Pattillo, CB; Teng, X; Thoma, S; Venkatesh, PK, 2010)
"We report a 1-month-old infant with Kawasaki disease and peripheral gangrene."1.33Infantile Kawasaki disease and peripheral gangrene. ( Durall, AL; Mullett, CJ; Phillips, JR; Weisse, ME, 2006)
"Adverse cardiac events were defined as congestive heart failure (CHF), myocardial infarction (MI), unstable angina (USA), and ventricular arrhythmias."1.31An abnormal dipyridamole thallium/sestamibi fails to predict long-term cardiac events in vascular surgery patients. ( de Virgilio, C; Donayre, C; Elbassir, M; Ephraim, L; Toosie, K; Wall, DB; White, R, 2001)
"The diazoxide-mediated increase in the forearm blood flow ratio (infused/control arm) was significantly less pronounced after glibenclamide than after acarbose (290 +/- 58% and 561 +/- 101% respectively; P<0."1.31Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes. ( Abbink, EJ; Lutterman, JA; Pickkers, P; Russel, FG; Smits, P; Tack, CJ; van Rosendaal, AJ, 2002)
"Indications for surgery included vertebrobasilar insufficiency (22."1.30Carotid-subclavian bypass for subclavian artery revascularization: long-term follow-up and effect of antiplatelet therapy. ( Dresler, C; Haverich, A; Wahlers, T; Wittwer, T, 1998)
"Method of complex surgical treatment of inguinal hernia in children, basing on the early conduction of surgical correction of pathology, application of microsurgical technique of the operation conduction, using of pharmacologic defense of hematotesticular barrier and medicinal therapy of the man sexual gland ischemia, was elaborated and substantiated."1.30[Substantiation of complex surgical treatment of inguinal hernia in children based on pathogenetic criteria]. ( Horbatiuk, OM, 1998)
"Dipyridamole pretreatment did not affect the right kidney, but it intensified the reductions in left kidney CPAH, CIn, and FF."1.27The effect of dipyridamole on the initiation phase of postischemic acute renal failure in rats. ( Bidani, AK; Churchill, PC; Lin, JJ, 1987)
"1 The effects of propranolol and practolol, at equivalent myocardial beta-adrenoceptor blocking doses, (as assessed by the degree of shift of isoprenaline dose-response curves) were investigated in anaesthetized greyhounds before and after acute coronary artery ligation."1.26Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction. ( Marshall, RJ; Parratt, JR, 1976)

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-199041 (50.00)18.7374
1990's16 (19.51)18.2507
2000's14 (17.07)29.6817
2010's11 (13.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bath, PM1
Woodhouse, LJ1
Appleton, JP1
Beridze, M1
Christensen, H1
Dineen, RA1
Duley, L1
England, TJ1
Flaherty, K1
Havard, D1
Heptinstall, S1
James, M1
Krishnan, K1
Markus, HS1
Montgomery, AA1
Pocock, SJ1
Randall, M1
Ranta, A1
Robinson, TG1
Scutt, P1
Venables, GS1
Sprigg, N1
Carboni, GP1
Sedati, P1
De Marco, E1
Azarbal, A1
Clavijo, L1
Gaglia, MA1
Serebruany, V1
Sabaeva, E1
Booze, C1
Atar, OD1
Eisert, C1
Hanley, D1
Venkatesh, PK1
Pattillo, CB3
Branch, B1
Hood, J1
Thoma, S1
Illum, S1
Pardue, S2
Teng, X1
Patel, RP2
Kevil, CG3
Zakavi, SR1
Taherpour, M1
Saleh, F1
Sadeghi, R1
Kakhki, VR1
Fang, K1
Terracciano, J1
Bir, SC1
Branch, BG1
Greber, E1
Shen, X1
Johnson, NP1
Lance Gould, K1
Aw, D1
Sharma, JC1
Grenz, A1
Bauerle, JD1
Dalton, JH1
Ridyard, D1
Badulak, A1
Tak, E1
McNamee, EN1
Clambey, E1
Moldovan, R1
Reyes, G1
Klawitter, J1
Ambler, K1
Magee, K1
Christians, U1
Brodsky, KS1
Ravid, K1
Choi, DS1
Wen, J1
Lukashev, D1
Blackburn, MR1
Osswald, H1
Coe, IR1
Nürnberg, B1
Haase, VH1
Xia, Y1
Sitkovsky, M1
Eltzschig, HK1
Ferreira-González, L1
Trigás-Ferrín, M1
Rubin, EP1
Sesma, P1
CASELLAS BERNAT, A1
TRILLA SANCHEZ, E1
DE-VOS BERRUETA, M1
GAUSI GENE, C1
HOELSCHER, B1
Rao, U1
Weston, C1
Lindgren, A1
Husted, S1
Staaf, G1
Ziegler, B1
Jones, L1
Griffin, S1
Palmer, S1
Main, C1
Orton, V1
Sculpher, M1
Sudlow, C1
Henderson, R1
Hawkins, N1
Riemsma, R1
Heston, TF1
Sigg, DM1
Durall, AL1
Phillips, JR1
Weisse, ME1
Mullett, CJ1
Meijer, P1
Wouters, CW1
van den Broek, PH1
Scheffer, GJ1
Riksen, NP1
Smits, P2
Rongen, GA1
Moir, TW1
DeBra, DW1
Garvin, PJ2
Carney, K2
Jellinek, M2
Niehoff, M1
Castaneda, M1
Codd, JE2
Liguori, J1
Werres, R1
Rothfeld, D1
Fradà, G1
Okiye, S1
Viinikka, L1
Kärkölä, P1
Pokela, R1
Ylikorkala, O1
Tavazzi, L1
Previtali, M1
Salerno, JA1
Chimienti, M1
Ray, M1
Medici, A1
Specchia, G1
Bobba, P1
Broomé, A1
Davidsson, T1
Eklöf, B1
Hansson, L1
Morris-Jones, W1
Preston, FE1
Greaney, M1
Chatterjee, DK1
DelBeccaro, EJ1
Robson, MC1
Heggers, JP1
Swaminathan, R1
Bajnok, L1
Kozlovszky, B1
Varga, J1
Antalffy, J1
Olvasztó, S1
Fülöp, T1
Connor, SJ1
Nukada, H1
Sarin, S1
Shami, SK1
Cheatle, TR1
Bearn, P1
Scurr, JH1
Coleridge Smith, PD1
Kresowik, TF1
Hoballah, JJ1
Sharp, WJ1
Corson, JD1
Wittwer, T1
Wahlers, T1
Dresler, C1
Haverich, A1
Horbatiuk, OM1
Cohen, MC1
Curran, PJ1
L'Italien, GJ1
Mittleman, MA1
Zarich, SW1
Rosen, SD1
Lorenzoni, R1
Kaski, JC1
Foale, RA1
Camici, PG1
Holdright, DR1
Dodi, C1
Cortigiani, L1
Masini, M1
Olivotto, I1
Azzarelli, A1
Nannini, E1
Bergmann, SR1
de Virgilio, C1
Wall, DB1
Ephraim, L1
Toosie, K1
Donayre, C1
White, R1
Elbassir, M1
Wolf, YG1
Landersberg, G1
Mosseri, M1
Schechter, D1
Anner, H1
Weissman, C1
Berlatzky, Y1
Karimov, ZZ1
Bakhritdinov, FSh1
Trynkin, AV1
Abbink, EJ1
Pickkers, P1
van Rosendaal, AJ1
Lutterman, JA1
Tack, CJ1
Russel, FG1
Takeda, K1
Nakagawa, Y1
Katono, Y1
Imai, S1
Callis, M1
Weiss, HJ2
Guiraud, B1
David, J1
Géraud, G1
Biermé, R1
Rascol, A1
Porter, JM1
Goodnight, SH1
Gotshall, RA1
Harker, LA1
Marshall, RJ2
Parratt, JR2
Baumgartner, I1
Schalch, I1
Bollinger, A1
Gruel, Y1
Lermusiaux, P1
Lang, M1
Darnige, L1
Rupin, A1
Delahousse, B1
Guilmot, JL1
Leroy, J1
Hugtenburg, JG1
Mathy, MJ1
de Haan, N1
Beckeringh, JJ1
van Zwieten, PA1
McCollum, C1
Kenchington, G1
Alexander, C1
Franks, PJ1
Greenhalgh, RM1
Knight, KR1
Kawabata, H1
Coe, SA1
Angus, JA1
O'Brien, BM2
Sakai, K1
Armbrecht, JJ1
Buxton, DB1
Schelbert, HR1
Tsuya, T1
Okada, M1
Horie, H1
Ishikawa, K1
Picano, E1
Berne, RM1
Belardinelli, L1
Lin, JJ1
Churchill, PC1
Bidani, AK1
Lewen, MK1
Labovitz, AJ1
Kern, MJ1
Chaitman, BR1
Sax, FL1
Cannon, RO1
Hanson, C1
Epstein, SE1
Wilding, RP1
Flute, PT1
Hahn, N1
Felix, R1
Hayhurst, JW1
Ishida, H1
Baxter, TJ1
Calman, KC1
Cibulski, AA1
Lehan, PH1
Timmis, HH1
Becker, RM1
Shizgal, HM1
Dobell, AR1
Ledingham, IM1
Howenstine, JA1
Slaton, P1
Spitalny, A1
Lee, J1
Schoen, HR1
Voss, R1
Ruile, K1
Wildberger, JE1
Gerlach, E1
Deuticke, B1
Seeman, T1
Kaltenbach, M1
Kübler, W1
Spieckermann, PG1
Bretschneider, HJ1
Winbury, MM1
Losada, M1
Kissil, D1
Howe, BB1
Pensinger, RR1
Kontos, HA1
Goldin, D1
Richardson, DW1
Patterson, JL1
Schlosser, V1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?[NCT00851175]Phase 48 participants (Anticipated)Interventional2009-03-31Completed
The Impact of Cardiac Rehabilitation on Angina Frequency, Psychological Morbidity and Quality of Life in Women With Syndrome X[NCT00123617]Phase 264 participants (Actual)Interventional2003-01-31Completed
CORonary MICrovascular Angina (CorMicA): a Randomised, Controlled, Pilot Trial[NCT03193294]151 participants (Actual)Interventional2016-11-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for dipyridamole and Ischemia

ArticleYear
Antiplatelet therapy for peripheral arterial disease and critical limb ischemia: guidelines abound, but where are the data?
    Journal of cardiovascular pharmacology and therapeutics, 2015, Volume: 20, Issue:2

    Topics: Aspirin; Cilostazol; Dipyridamole; Endovascular Procedures; Extremities; Humans; Ischemia; Periphera

2015
Reperfusion of chronic tissue ischemia: nitrite and dipyridamole regulation of innate immune responses.
    Annals of the New York Academy of Sciences, 2010, Volume: 1207

    Topics: Animals; Dipyridamole; Down-Regulation; Humans; Immunity, Innate; Inflammation; Ischemia; Neovascula

2010
Antiplatelets in secondary stroke prevention: should clopidogrel be the first choice?
    Postgraduate medical journal, 2012, Volume: 88, Issue:1035

    Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Ischemia; Ischemic Attack, Transient; Platelet Aggregati

2012
Antiplatelet agents in atherothrombotic diseases.
    Hospital medicine (London, England : 1998), 2004, Volume: 65, Issue:2

    Topics: Arteriosclerosis; Aspirin; Clopidogrel; Dipyridamole; Humans; Ischemia; Platelet Aggregation Inhibit

2004
Clinical effectiveness and cost-effectiveness of clopidogrel and modified-release dipyridamole in the secondary prevention of occlusive vascular events: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2004, Volume: 8, Issue:38

    Topics: Aspirin; Clopidogrel; Cost-Benefit Analysis; Delayed-Action Preparations; Diarrhea; Dipyridamole; Dr

2004
When do vascular surgeons prescribe antiplatelet therapy? Current attitudes.
    European journal of vascular surgery, 1993, Volume: 7, Issue:1

    Topics: Angioplasty, Balloon; Arteriosclerosis; Aspirin; Dipyridamole; Graft Occlusion, Vascular; Humans; Is

1993
Antiplatelet drugs-a new pharmacologic approach to the prevention of thrombosis.
    American heart journal, 1976, Volume: 92, Issue:1

    Topics: Anticoagulants; Aspirin; Blood Platelets; Brain; Clofibrate; Dextrans; Dipyridamole; Humans; Ischemi

1976
Dipyridamole-echocardiography test: historical background and physiologic basis.
    European heart journal, 1989, Volume: 10, Issue:4

    Topics: Coronary Disease; Dipyridamole; Echocardiography; Exercise Test; Humans; Ischemia

1989

Trials

10 trials available for dipyridamole and Ischemia

ArticleYear
Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.
    Lancet (London, England), 2018, 03-03, Volume: 391, Issue:10123

    Topics: Acute Disease; Aged; Aspirin; Brain Ischemia; Clopidogrel; Denmark; Dipyridamole; Drug Therapy, Comb

2018
Distribution of dipyridamole in blood components among post-stroke patients treated with extended release formulation.
    Thrombosis and haemostasis, 2009, Volume: 102, Issue:3

    Topics: Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Blood Platelets; Delayed-Action Preparations;

2009
Dipyridamole and headache--a pilot study of initial dose titration.
    Journal of the neurological sciences, 2004, Aug-30, Volume: 223, Issue:2

    Topics: Aged; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Follow-Up Studies; Headache; Humans;

2004
Dipyridamole enhances ischaemia-induced reactive hyperaemia by increased adenosine receptor stimulation.
    British journal of pharmacology, 2008, Volume: 153, Issue:6

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Forearm; Humans; Hyperemia

2008
Platelet inhibition with ASA/dipyridamole after percutaneous balloon angioplasty in patients with symptomatic lower limb arterial disease. A prospective double-blind trial. Study group on pharmacological treatment after PTA.
    European journal of vascular surgery, 1994, Volume: 8, Issue:1

    Topics: Aged; Angiography; Angioplasty, Balloon; Aspirin; Dipyridamole; Double-Blind Method; Drug Combinatio

1994
Effect of alpha1-adrenoceptor blockade on coronary vasodilator reserve in cardiac syndrome X.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angina Pectoris; Dipyridamole; Double-Blind Method; Doxaz

1999
Proceedings: Prevention of ischemic cerebro vascular accident: a long term clinical trial with vasodilator and antiaggregating drugs.
    Thrombosis et diathesis haemorrhagica, 1975, Sep-30, Volume: 34, Issue:1

    Topics: Aspirin; Brain; Clinical Trials as Topic; Dihydroergotoxine; Dipyridamole; Ergoloid Mesylates; Human

1975
[Double-blind study of the effect of dipyridamole in patients with intermittent claudication].
    VASA. Zeitschrift fur Gefasskrankheiten, 1992, Volume: 21, Issue:4

    Topics: Aged; Dipyridamole; Double-Blind Method; Exercise Test; Female; Humans; Intermittent Claudication; I

1992
PTFE or HUV for femoro-popliteal bypass: a multi-centre trial.
    European journal of vascular surgery, 1991, Volume: 5, Issue:4

    Topics: Arterial Occlusive Diseases; Aspirin; Bioprosthesis; Blood Vessel Prosthesis; Combined Modality Ther

1991
Effect of dipyridamole at the usual oral dose on exercise-induced myocardial ischemia in stable angina pectoris.
    The American journal of cardiology, 1990, Aug-01, Volume: 66, Issue:3

    Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Coronary Circulation; Dipyridamole; Double-Blind

1990

Other Studies

64 other studies available for dipyridamole and Ischemia

ArticleYear
Anomalous left main coronary artery origin, silent ischaemia, risk of sudden death: a triad detected by combining coronary CT and dipyridamole SPECT.
    BMJ case reports, 2013, Aug-05, Volume: 2013

    Topics: Aged; Coronary Vessel Anomalies; Death, Sudden, Cardiac; Dipyridamole; Humans; Ischemia; Male; Multi

2013
Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway.
    Cardiovascular research, 2010, Mar-01, Volume: 85, Issue:4

    Topics: Animals; Cell Division; Chronic Disease; Cyclic AMP-Dependent Protein Kinases; Dipyridamole; Dose-Re

2010
Electrocardiographic changes after dipyridamole infusion in patients undergoing myocardial perfusion imaging.
    Nuclear medicine communications, 2010, Volume: 31, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Dipyridamole; Electrocardiography; Female; Humans; Infusion Pumps; I

2010
Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress.
    Free radical biology & medicine, 2011, Jan-15, Volume: 50, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Dipyridamole; Disease Models, Animal; Hindlimb; Hyperchole

2011
Dipyridamole reversal using theophylline during aminophylline shortage.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2011, Volume: 18, Issue:6

    Topics: Aminophylline; Dipyridamole; Drug Substitution; Humans; Ischemia; Theophylline; Therapeutic Equivale

2011
Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:2

    Topics: Acute Kidney Injury; Adenosine; Animals; Cell Line; Chimerism; Dipyridamole; Equilibrative Nucleosid

2012
Pituitary apoplexy after myocardial perfusion scintigraphy.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10

    Topics: Adenoma; Aged; Angina, Unstable; Anticoagulants; Cardiac Pacing, Artificial; Dipyridamole; Female; H

2012
[Clinico-experipyrimido (5,4-d) pyrimidine].
    Revista espanola de cardiologia, 1963, Volume: 16

    Topics: Angina Pectoris; Dipyridamole; Heart Diseases; Humans; Intracranial Embolism; Intracranial Embolism

1963
[STUDIES ON THE PROLONGATION AND SURVIVAL TIME OF ISOLATED RABBIT HEART AFTER PRELIMINARY TREATMENT WITH 2,6-BIS-(DIETHANOLAMINO)-4,8-DIPIPERIDNOPYRIMIDO(5,4-D)PYRIMIDINE].
    Langenbecks Archiv fur klinische Chirurgie ... vereinigt mit Deutsche Zeitschrift fur Chirurgie, 1964, Nov-17, Volume: 308

    Topics: Adenosine Triphosphate; Animals; Dipyridamole; Heart; Heart Arrest; Ischemia; Pharmacology; Pyrimidi

1964
Quantifying transient ischemic dilation using gated SPECT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:12

    Topics: Aged; Dipyridamole; Female; Gated Blood-Pool Imaging; Heart Ventricles; Humans; Image Processing, Co

2005
Infantile Kawasaki disease and peripheral gangrene.
    The Journal of pediatrics, 2006, Volume: 149, Issue:1

    Topics: Abciximab; Amputation, Surgical; Anti-Bacterial Agents; Antibodies, Monoclonal; Anticoagulants; Anti

2006
Effect of left ventricular hypertension, ischemia and vasoactive drugs on the myocardial distribution of coronary flow.
    Circulation research, 1967, Volume: 21, Issue:1

    Topics: Animals; Coronary Vessels; Dipyridamole; Electrocardiography; Heart; Heart Ventricles; Hypertension;

1967
The effects of ATP-MgCl2 and dipyridamole in cold-storage preservation.
    The Journal of surgical research, 1983, Volume: 34, Issue:5

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cold Temperature; Dipyridamole; Dogs; Female;

1983
Percutaneous transluminal coronary angioplasty at a community hospital--initial experience.
    The Journal of the Medical Society of New Jersey, 1982, Volume: 79, Issue:1

    Topics: Adult; Angioplasty, Balloon; Aspirin; Coronary Vessels; Dipyridamole; Female; Hospitals, Community;

1982
[Ischemic syndrome of the lower extremities from immersion in hot water].
    Minerva medica, 1984, Oct-27, Volume: 75, Issue:41

    Topics: Aged; Dipyridamole; Hot Temperature; Humans; Ischemia; Male; Platelet Aggregation; Toes

1984
The effect of ATP-MgCl2 and dipyridamole pretreatment in renal preservation.
    The Journal of surgical research, 1982, Volume: 32, Issue:1

    Topics: Adenosine Triphosphate; Animals; Dipyridamole; Dogs; Female; Graft Survival; Ischemia; Kidney; Kidne

1982
Lack of effect of ischemia and dipyridamole on prostacyclin production in arteriosclerosis obliterans.
    Prostaglandins, 1981, Volume: 21, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Aged; Arteriosclerosis Obliterans; Dipyridamole; Epoprostenol; Humans;

1981
Dipyridamole test in angina pectoris: diagnostic value and pathophysiological implications.
    Cardiology, 1982, Volume: 69, Issue:1

    Topics: Adult; Aged; Angina Pectoris; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary

1982
Effect of platelet aggregation inhibitors on the rate of thrombectomy following arterial reconstructions with Gore-Tex prostheses: a retrospective study.
    VASA. Zeitschrift fur Gefasskrankheiten, 1982, Volume: 11, Issue:3

    Topics: Aspirin; Blood Vessel Prosthesis; Dipyridamole; Humans; Ischemia; Leg; Platelet Aggregation; Postope

1982
Gangrene of the toes with palpable peripheral pulses.
    Annals of surgery, 1981, Volume: 193, Issue:4

    Topics: Aged; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Gangrene; Humans; Ischemia; Male; Mi

1981
The use of specific thromboxane inhibitors to preserve the dermal microcirculation after burning.
    Surgery, 1980, Volume: 87, Issue:2

    Topics: Animals; Burns; Dipyridamole; Female; Guinea Pigs; Heterocyclic Compounds; Imidazoles; Ischemia; Met

1980
Technetium-99m sestamibi scintigraphy for the assessment of lower extremity ischaemia in peripheral arterial disease.
    European journal of nuclear medicine, 1994, Volume: 21, Issue:12

    Topics: Dipyridamole; Female; Heart; Humans; Ischemia; Leg; Male; Middle Aged; Peripheral Vascular Diseases;

1994
Vasodilating effect of dipyridamole on rat endoneurial vessels: morphometric study.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1993, Volume: 45, Issue:5-6

    Topics: Animals; Dipyridamole; Ischemia; Male; Peripheral Nerves; Peripheral Nervous System Diseases; Random

1993
Cardiac screening tests prior to lower extremity revascularization: routine versus selective application.
    Seminars in vascular surgery, 1997, Volume: 10, Issue:1

    Topics: Coronary Disease; Dipyridamole; Heart Function Tests; Humans; Inguinal Canal; Ischemia; Leg; Periphe

1997
Carotid-subclavian bypass for subclavian artery revascularization: long-term follow-up and effect of antiplatelet therapy.
    Angiology, 1998, Volume: 49, Issue:4

    Topics: Adult; Aged; Angiography; Anticoagulants; Arm; Arterial Occlusive Diseases; Aspirin; Blood Vessel Pr

1998
[Substantiation of complex surgical treatment of inguinal hernia in children based on pathogenetic criteria].
    Klinichna khirurhiia, 1998, Issue:12

    Topics: Age Factors; Antioxidants; Ascorbic Acid; Aspirin; Blood-Testis Barrier; Child; Dipyridamole; Hernia

1998
Long-term prognostic value of preoperative dipyridamole thallium imaging and clinical indexes in patients with diabetes mellitus undergoing peripheral vascular surgery.
    The American journal of cardiology, 1999, Apr-01, Volume: 83, Issue:7

    Topics: Aged; Diabetic Angiopathies; Dipyridamole; Female; Follow-Up Studies; Heart Diseases; Humans; Ischem

1999
The role of pharmacological stress echo for evaluating chest pain in women.
    European heart journal, 2001, Volume: 22, Issue:2

    Topics: Chest Pain; Coronary Disease; Dipyridamole; Dobutamine; Echocardiography; Electrocardiography; Exerc

2001
The incremental prognostic value of pharmacological stress echo over exercise electrocardiography in women with chest pain of unknown origin.
    European heart journal, 2001, Volume: 22, Issue:2

    Topics: Aged; Chest Pain; Dipyridamole; Dobutamine; Echocardiography; Electrocardiography; Exercise Test; Fe

2001
Aggrenox and stress testing.
    Circulation, 2001, Feb-27, Volume: 103, Issue:8

    Topics: Adenosine; Aspirin; Aspirin, Dipyridamole Drug Combination; Dipyridamole; Drug Combinations; Humans;

2001
An abnormal dipyridamole thallium/sestamibi fails to predict long-term cardiac events in vascular surgery patients.
    Annals of vascular surgery, 2001, Volume: 15, Issue:2

    Topics: Aged; Aortic Diseases; Cause of Death; Dipyridamole; Female; Follow-Up Studies; Heart Failure; Human

2001
Preoperative dipyridamole-thallium scanning, selective coronary revascularization and long-term survival in patients with critical lower limb ischemia.
    The Journal of cardiovascular surgery, 2001, Volume: 42, Issue:1

    Topics: Aged; Angioplasty, Balloon, Coronary; Chronic Disease; Coronary Artery Bypass; Coronary Disease; Dip

2001
[Prolonged intra-arterial therapy in surgical treatment of patients with critical lower limb ischemia].
    Khirurgiia, 2001, Issue:12

    Topics: Actihaemyl; Adult; Aged; Aged, 80 and over; Amputation, Surgical; Anticoagulants; Critical Care; Dip

2001
Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes.
    Clinical science (London, England : 1979), 2002, Volume: 102, Issue:3

    Topics: Acarbose; Acetylcholine; Cross-Over Studies; Diabetes Mellitus, Type 2; Diazoxide; Dipyridamole; Dou

2002
Effects of coronary vasodilators on large and small coronary arteries of dogs.
    Japanese heart journal, 1977, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Arteries; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs; Erythritol

1977
[Ischemic lesions in polycythaemia vera (author's transl)].
    Sangre, 1977, Volume: 22, Issue:6

    Topics: Aspirin; Dipyridamole; Female; Foot; Humans; Ischemia; Male; Middle Aged; Pain; Polycythemia Vera; S

1977
The role of the platelet in coagulation and clinical thrombotic events.
    American journal of surgery, 1977, Volume: 134, Issue:2

    Topics: Blood Coagulation; Blood Platelets; Cell Survival; Cerebrovascular Disorders; Coronary Disease; Dipy

1977
Using antithrombotic therapy in ischemic cerebrovascular disease.
    Geriatrics, 1977, Volume: 32, Issue:11

    Topics: Aspirin; Brain; Cerebrovascular Disorders; Dipyridamole; Fibrinolytic Agents; Heparin; Humans; Intra

1977
Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction.
    British journal of pharmacology, 1976, Volume: 57, Issue:2

    Topics: Animals; Body Temperature; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs; Female; Hemod

1976
Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis.
    Annals of vascular surgery, 1991, Volume: 5, Issue:6

    Topics: Aged; Aorta, Abdominal; Aspirin; Dipyridamole; Female; Femoral Vein; Heparin; Humans; Iliac Artery;

1991
The influence of calcium antagonists on the adenine nucleotide metabolism in the guinea-pig working heart during ischaemia and reperfusion.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:5

    Topics: Adenine Nucleotides; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dipyri

1991
Prostacyclin and prostanoid modifiers aid ischemic skin flap survival.
    The Journal of surgical research, 1991, Volume: 50, Issue:2

    Topics: Animals; Dipyridamole; Epoprostenol; Graft Survival; Imidazoles; Ischemia; Prostaglandins, Synthetic

1991
Validation of [1-11C]acetate as a tracer for noninvasive assessment of oxidative metabolism with positron emission tomography in normal, ischemic, postischemic, and hyperemic canine myocardium.
    Circulation, 1990, Volume: 81, Issue:5

    Topics: Acetates; Animals; Carbon Dioxide; Carbon Radioisotopes; Coronary Circulation; Dipyridamole; Dogs; H

1990
Effects of hypoxia and ischaemia on coronary vascular resistance, A-V node conduction and S-A node excitation.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 694

    Topics: Adenine Nucleotides; Adenosine; Aminophylline; Atrioventricular Node; Coronary Circulation; Coronary

1985
The effect of dipyridamole on the initiation phase of postischemic acute renal failure in rats.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:7

    Topics: Acute Kidney Injury; Animals; Blood Pressure; Dipyridamole; Glomerular Filtration Rate; Ischemia; Ki

1987
Prolonged myocardial ischemia after intravenous dipyridamole thallium imaging.
    Chest, 1987, Volume: 92, Issue:6

    Topics: Cardiomyopathies; Coronary Disease; Dipyridamole; Echocardiography; Electrocardiography; Female; Hum

1987
Impaired forearm vasodilator reserve in patients with microvascular angina. Evidence of a generalized disorder of vascular function?
    The New England journal of medicine, 1987, Nov-26, Volume: 317, Issue:22

    Topics: Adult; Angina Pectoris; Coronary Circulation; Dipyridamole; Female; Forearm; Humans; Ischemia; Male;

1987
Impaired forearm vasodilator reserve in patients with microvascular angina. Evidence of a generalized disorder of vascular function?
    The New England journal of medicine, 1987, Nov-26, Volume: 317, Issue:22

    Topics: Adult; Angina Pectoris; Coronary Circulation; Dipyridamole; Female; Forearm; Humans; Ischemia; Male;

1987
Impaired forearm vasodilator reserve in patients with microvascular angina. Evidence of a generalized disorder of vascular function?
    The New England journal of medicine, 1987, Nov-26, Volume: 317, Issue:22

    Topics: Adult; Angina Pectoris; Coronary Circulation; Dipyridamole; Female; Forearm; Humans; Ischemia; Male;

1987
Impaired forearm vasodilator reserve in patients with microvascular angina. Evidence of a generalized disorder of vascular function?
    The New England journal of medicine, 1987, Nov-26, Volume: 317, Issue:22

    Topics: Adult; Angina Pectoris; Coronary Circulation; Dipyridamole; Female; Forearm; Humans; Ischemia; Male;

1987
Letter: Dipyridamole in peripheral upper-limb ischaemia.
    Lancet (London, England), 1974, May-18, Volume: 1, Issue:7864

    Topics: Administration, Oral; Aged; Arm; Arterial Occlusive Diseases; Dipyridamole; Female; Humans; Ischemia

1974
[Proceedings: Microcirculation and ventricular-wall function in the normal and partially ischemia-damaged myocardium under pharmacologic influence in animal experiment].
    Zeitschrift fur Kardiologie, 1974, Volume: 0, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Animals; Coronary Vessels; Digoxin; Dipyridamole; Dogs; Heart; Ischemia

1974
Experimental digital replantation after prolonged cooling.
    The Hand, 1974, Volume: 6, Issue:2

    Topics: Animals; Arteries; Aspirin; Autopsy; Cold Temperature; Dipyridamole; Fingers; Graft Rejection; Haplo

1974
The prediction of organ viability. II. Testing an hypothesis.
    Cryobiology, 1974, Volume: 11, Issue:1

    Topics: Adenine Nucleotides; Animals; Dipyridamole; Insulin; Ischemia; Kidney; Models, Biological; Organ Pre

1974
Retrograde flow technique vs. krypton-85 clearance technique for estimation of myocardial collaterals.
    The American journal of physiology, 1972, Volume: 223, Issue:5

    Topics: Animals; Blood Pressure; Collateral Circulation; Coronary Circulation; Coronary Disease; Coronary Ve

1972
Distribution of coronary blood flow during cardiopulmonary bypass in pigs.
    The Annals of thoracic surgery, 1973, Volume: 16, Issue:3

    Topics: Animals; Chromium Isotopes; Coronary Circulation; Dipyridamole; Extracorporeal Circulation; Heart Ve

1973
Drug-induced changes in blood flow in normal and ischaemic regions of the canine myocardium.
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Amino Alcohols; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs;

1973
Inhibition of platelet-induced thrombus formation.
    Schweizerische medizinische Wochenschrift, 1974, Jan-26, Volume: 104, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Brain Diseases; Dipyridamole; Epinephrin

1974
Flank pain and hematuria in a young man with renal artery arteriosclerosis: remission of symptoms during administration of dipyridamole.
    The Journal of urology, 1974, Volume: 112, Issue:1

    Topics: Adult; Angiography; Arteriosclerosis; Dipyridamole; Hematuria; Hemorrhage; Humans; Ischemia; Kidney;

1974
[Animal experimental metabolic studies of the kdneys and their significance for transplantation].
    Zentralblatt fur Chirurgie, 1967, Jun-03, Volume: 92, Issue:22

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Dipyridamole; Dogs; Injections, Intravenous; I

1967
[Comparative studies on the formation of adenosine in the myocardium of different animal species in oxygen deficiency].
    Klinische Wochenschrift, 1966, Nov-15, Volume: 44, Issue:22

    Topics: Adenine Nucleotides; Aminohydrolases; Animals; Cats; Dipyridamole; Dogs; Guinea Pigs; Haplorhini; He

1966
Pharmacological, rheological and surgical attempts to improve myocardial blood flow during coronary occlusion in dogs.
    Acta chirurgica Scandinavica. Supplementum, 1969, Volume: 400

    Topics: Animals; Blood Viscosity; Collateral Circulation; Coronary Disease; Coronary Vessels; Dipyridamole;

1969
[Drug therapy of angina pectoris. Evaluation of various drugs by means of work tests].
    Arzneimittel-Forschung, 1970, Volume: 20

    Topics: Angina Pectoris; Angiography; Anti-Arrhythmia Agents; Coumarins; Dipyridamole; Electrocardiography;

1970
Influence of dipyridamol (Persantin) on myocardial adenosine metabolism.
    Journal of molecular and cellular cardiology, 1970, Volume: 1, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport; Cell Membrane Permeability; Coronary

1970
Pentaerythritoltetranitrate and dipyridamole on cardiac nutritive flow and blood content.
    The American journal of physiology, 1971, Volume: 220, Issue:5

    Topics: Animals; Autoradiography; Blood Flow Velocity; Collateral Circulation; Coronary Vessels; Dipyridamol

1971
Effect of dipyridamole on vasodilator responses to ischemia, hypoxia, ATP, and AMP.
    The American journal of physiology, 1968, Volume: 214, Issue:1

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Blood Vessels; Dipyridamole; D

1968
[Immediate postischemic sufficiency of the warm-blooded heart and its pharmacologic control].
    Bruns' Beitrage fur klinische Chirurgie, 1965, Volume: 211, Issue:3

    Topics: Animals; Blood Pressure Determination; Cardiac Surgical Procedures; Dipyridamole; Dogs; Heart Failur

1965