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dipyridamole and Intracranial Arteriosclerosis

dipyridamole has been researched along with Intracranial Arteriosclerosis in 16 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Intracranial Arteriosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Research Excerpts

ExcerptRelevanceReference
"The number of fatal and non fatal cerebral infarction was 31 in the P group, 17 in the ASA group, and 18 in the ASA + D group."2.65[The A.I.C.L.A. controlled cooperative trial. Secondary prevention of cerebral ischemic accidents due to atherosclerosis by aspirin and dipyridamole. 3: Results]. ( Bousser, MG; Eschwege, E; Haguenau, M; Lefauconnier, JM; Thibult, N; Touboul, D; Touboul, PJ, 1983)
"Nifedipine was demonstrated to potentiate relaxation effect of prostacyclin at the level of sarcolemmal calcium transport, while cavinton and dipyridamole had an analogous influence, redistributing calcium in the intracellular stores."1.27[Effect of prostacyclin on the cerebral vessels and its pharmacological modification]. ( Akopov, SE; Balaian, BG; Gabrielian, ES, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199013 (81.25)18.7374
1990's1 (6.25)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Simard, T1
Motazedian, P1
Dhaliwal, S1
Di Santo, P1
Jung, RG1
Ramirez, FD1
Labinaz, A1
Short, S1
Parlow, S1
Joseph, J1
Rasheed, A1
Rockley, M1
Marbach, J1
Domecq, MC1
Russo, JJ1
Chong, AY1
Beanlands, RS1
Hibbert, B1
Gomez, CR1
Qureshi, AI1
Bousser, MG3
Eschwege, E3
Haguenau, M3
Lefauconnier, JM3
Thibult, N2
Touboul, D3
Touboul, PJ3
Kistler, JP1
Ropper, AH1
Heros, RC1
Dujovny, M1
Kossovsky, N1
Loubeau, JM1
Nelson, D1
McManus, G1
De Marinis, M1
Fieschi, C1
Prencipe, M1
Falchetti, R1
Paolucci, S1
Yatsu, FM1
Paredero Del Bosque Martin, V1
Eninia, GI2
Purinia, IV1
Timofeeva, TN1
Borasi, G1
Pallestrini, EA1
Sperati, G1
Gabrielian, ES1
Akopov, SE1
Balaian, BG1
Smeltere, ES1
Godlevska, MA1
Logina, IP1
Millikan, CH1

Reviews

2 reviews available for dipyridamole and Intracranial Arteriosclerosis

ArticleYear
Revisiting the Evidence for Dipyridamole in Reducing Restenosis: A Systematic Review and Meta-analysis.
    Journal of cardiovascular pharmacology, 2021, 04-01, Volume: 77, Issue:4

    Topics: Animals; Coronary Artery Disease; Coronary Restenosis; Dipyridamole; Endovascular Procedures; Humans

2021
Therapy of ischemic cerebral vascular disease due to atherothrombosis. (2).
    The New England journal of medicine, 1984, Jul-12, Volume: 311, Issue:2

    Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Auscultation; Basilar Artery; Blood Platelets;

1984

Trials

3 trials available for dipyridamole and Intracranial Arteriosclerosis

ArticleYear
[The A.I.C.L.A. controlled cooperative trial. Secondary prevention of cerebral ischemic accidents due to atherosclerosis by aspirin and dipyridamole. 3: Results].
    Revue neurologique, 1983, Volume: 139, Issue:5

    Topics: Aspirin; Brain Ischemia; Cerebral Infarction; Clinical Trials as Topic; Dipyridamole; Drug Therapy,

1983
["A.I.C.L.A." controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia. Part I: Protocol (author's transl)].
    Revue neurologique, 1981, Volume: 137, Issue:5

    Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Humans;

1981
[Controlled cooperative trial. Secondary prevention of atherosclerosis-related cerebral ischemic accidents by aspirin dipyridamole. 2: Description of subjects at the beginning of the trial].
    Revue neurologique, 1982, Volume: 138, Issue:1

    Topics: Aged; Aspirin; Brain Ischemia; Cerebral Infarction; Clinical Trials as Topic; Dipyridamole; Drug The

1982

Other Studies

11 other studies available for dipyridamole and Intracranial Arteriosclerosis

ArticleYear
Medical treatment of patients with intracranial atherosclerotic disease.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2009, Volume: 19 Suppl 1

    Topics: Anticoagulants; Aspirin; Atherosclerosis; Brain Ischemia; Cilostazol; Clopidogrel; Dipyridamole; Emb

2009
[Preliminary note on the therapeutic contribution of "RA 8" (Persantin) in neuropsychiatric manifestations of arteriosclerotic brain diseases].
    Jornal do medico, 1963, Feb-02, Volume: 50

    Topics: Brain Diseases; Dipyridamole; Humans; Intracranial Arteriosclerosis

1963
Scanning electron microscopic and X-ray energy spectrographic analysis of the inner surface of human atherosclerotic carotid plaques.
    Neurosurgery, 1981, Volume: 8, Issue:1

    Topics: Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Dipyridamole; Female; Humans; Intracrani

1981
Circulating platelet aggregates: a chronic platelet activation in patients with transient ischaemic attacks.
    Italian journal of neurological sciences, 1980, Volume: 1, Issue:3

    Topics: Aspirin; Cerebral Angiography; Dipyridamole; Humans; Intracranial Arteriosclerosis; Ischemic Attack,

1980
For your stroke-prone patients: a guide to drug treatment.
    Geriatrics, 1980, Volume: 35, Issue:2

    Topics: Aged; Antihypertensive Agents; Aspirin; Brain Diseases; Cerebral Angiography; Cerebrovascular Disord

1980
[Indications for surgical treatment and medical treatment of atherosclerosis].
    Minerva medica, 1980, Oct-20, Volume: 71, Issue:40

    Topics: Arteriosclerosis; Aspirin; Cholestyramine Resin; Clofibrate; Dextrothyroxine; Dipyridamole; Humans;

1980
[The effect of kavinton, trental, sermion and kurantil on the blood flow rate in individual segments of the cerebral arteries].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:1

    Topics: Blood Flow Velocity; Cerebral Arteries; Chronic Disease; Dipyridamole; Drug Evaluation; Female; Huma

1994
[The use of platelet aggregation-inhibiting drugs in central vestibular pathology caused by atherosclerotic vascular diseases].
    Annali di laringologia, otologia, rinologia, faringologia, 1975, Volume: 74, Issue:6

    Topics: Aspirin; Dipyridamole; Drug Evaluation; Humans; Intracranial Arteriosclerosis; Labyrinth Diseases; O

1975
[Effect of prostacyclin on the cerebral vessels and its pharmacological modification].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 102, Issue:12

    Topics: Cadaver; Cerebral Arteries; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Epoprost

1986
[Effect of antianginal agents on the cerebral circulatory indices in cerebral arteriosclerosis].
    Klinicheskaia meditsina, 1985, Volume: 63, Issue:9

    Topics: Adult; Amiodarone; Cerebrovascular Circulation; Chromonar; Dipyridamole; Drug Evaluation; Female; He

1985
Address of the president-elect: the indication for various methods of treatment of occlusive cerebrovascular disease.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Anticoagulants; Aspirin; Blood Pressure; Cardiac Output; Carotid Arteries; Cerebral Angiography; Cer

1973