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dipyridamole and Intermittent Claudication

dipyridamole has been researched along with Intermittent Claudication in 15 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.

Research Excerpts

ExcerptRelevanceReference
"32 patients (mean age 65 years, range 51-75 years) were included in this controlled, double blind study to evaluate the effect of dipyridamole in patients with intermittent claudication."9.07[Double-blind study of the effect of dipyridamole in patients with intermittent claudication]. ( Baumgartner, I; Bollinger, A; Schalch, I, 1992)
"32 patients (mean age 65 years, range 51-75 years) were included in this controlled, double blind study to evaluate the effect of dipyridamole in patients with intermittent claudication."5.07[Double-blind study of the effect of dipyridamole in patients with intermittent claudication]. ( Baumgartner, I; Bollinger, A; Schalch, I, 1992)
" Moreover, patients without any history of coronary heart disease and showing a normal resting ECG underwent a bicycle exercise test or a dipyridamole thallium scintigraphy to detect possible silent myocardial ischemia."3.69Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM. ( Brun, JM; Cohen, M; Gambert, P; Lagrost, L; Petit, JM; Vaillant, G; Vergès, BL, 1997)
"For this update the Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched June 2014) and the Cochrane Central Register of Controlled Trials (CENTRAL) (2014, Issue 5)."2.52Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery. ( Acosta, S; Bedenis, R; Lethaby, A; Maxwell, H; Prins, MH, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's5 (33.33)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bedenis, R1
Lethaby, A1
Maxwell, H1
Acosta, S1
Prins, MH1
Dörffler-Melly, J1
Schmidli, J1
Mahler, F2
Heidrich, H1
Bollinger, A2
Biland, L1
Brunner, U1
Kappert, A1
Krähenbühl, B1
Monti, M1
Nachbur, B1
Schneider, E1
Widmer, LK1
Kohler, TR1
Kaufman, JL1
Kacoyanis, G1
Clowes, A1
Donaldson, MC1
Kelly, E1
Skillman, J1
Couch, NP1
Whittemore, AD1
Mannick, JA1
Heinrich, F1
Verstraete, M1
Rose, EL1
Liu, XJ1
Henley, M1
Lewis, JD1
Raftery, EB1
Lahiri, A1
Darbar, D1
Gillespie, N1
Main, G1
Bridges, AB1
Kennedy, NS1
Pringle, TH1
McNeill, GP1
Vergès, BL1
Lagrost, L1
Vaillant, G1
Petit, JM1
Cohen, M1
Gambert, P1
Brun, JM1
Baumgartner, I1
Schalch, I1
Mannarino, E1
Pasqualini, L1
Innocente, S1
Scricciolo, V1
Rignanese, A1
Ciuffetti, G1
Di Perri, T1
Pasini, FL1
Pecchi, S1
De Franco, V1
Damiani, P1
Pasqui, AL1
Capecchi, PL1
Orrico, A1
Materazzi, M1
Domini, L1
Libretti, A2
Catalano, M2

Reviews

2 reviews available for dipyridamole and Intermittent Claudication

ArticleYear
Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery.
    The Cochrane database of systematic reviews, 2015, Feb-19, Issue:2

    Topics: Anastomosis, Surgical; Anticoagulants; Arteriosclerosis; Aspirin; Dipyridamole; Graft Occlusion, Vas

2015
[Peripheral arterial occlusions. Principles, possibilities and limits of conservative therapy].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1981, Apr-10, Volume: 57, Issue:10

    Topics: Ancrod; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cardiomyopathies; Dextrans; Digitalis

1981

Trials

6 trials available for dipyridamole and Intermittent Claudication

ArticleYear
Registry of prospective clinical trials--fifth report.
    Thrombosis and haemostasis, 1982, Dec-27, Volume: 48, Issue:3

    Topics: Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Double-Bl

1982
Prediction of late cardiac events by dipyridamole thallium scintigraphy in patients with intermittent claudication and occult coronary artery disease.
    The American journal of cardiology, 1996, Oct-01, Volume: 78, Issue:7

    Topics: Aged; Cardiac Catheterization; Coronary Disease; Dipyridamole; Female; Follow-Up Studies; Humans; In

1996
[Double-blind study of the effect of dipyridamole in patients with intermittent claudication].
    VASA. Zeitschrift fur Gefasskrankheiten, 1992, Volume: 21, Issue:4

    Topics: Aged; Dipyridamole; Double-Blind Method; Exercise Test; Female; Humans; Intermittent Claudication; I

1992
Physical training and antiplatelet treatment in stage II peripheral arterial occlusive disease: alone or combined?
    Angiology, 1991, Volume: 42, Issue:7

    Topics: Aspirin; Combined Modality Therapy; Dipyridamole; Exercise Therapy; Female; Humans; Intermittent Cla

1991
Treatment of claudication with dipyridamole and aspirin.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:1

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Dipyridamole; Double-Blind Method; Drug Therapy, Com

1986
Treatment of claudication with dipyridamole and aspirin.
    Monographs on atherosclerosis, 1986, Volume: 14

    Topics: Adult; Aged; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combin

1986

Other Studies

7 other studies available for dipyridamole and Intermittent Claudication

ArticleYear
[Anticoagulation and antiaggregation in patients with peripheral arterial occlusive diseases].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:1

    Topics: Administration, Oral; Angioplasty, Balloon; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Bl

2003
[Therapy of peripheral arterial occlusive diseases. Round table conference].
    Schweizerische medizinische Wochenschrift, 1983, Dec-10, Volume: 113, Issue:49

    Topics: Alprostadil; Angioplasty, Balloon; Anti-Bacterial Agents; Anticoagulants; Arterial Occlusive Disease

1983
Effect of aspirin and dipyridamole on the patency of lower extremity bypass grafts.
    Surgery, 1984, Volume: 96, Issue:3

    Topics: Aged; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Double-Blind Method; Female; Graft Survival; H

1984
[Improvement of walking disability and conservative treatment. Guiding principles for drug treatment of chronic arterial occlusive disease (stage I and IIb)].
    Fortschritte der Medizin, 1984, Sep-27, Volume: 102, Issue:36

    Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Dipyridamole; Fibrinolytic Agents; Humans; Int

1984
Prognostic value of noninvasive cardiac tests in the assessment of patients with peripheral vascular disease.
    The American journal of cardiology, 1993, Jan-01, Volume: 71, Issue:1

    Topics: Aged; Cardiac Catheterization; Coronary Disease; Dipyridamole; Electrocardiography; Electrocardiogra

1993
Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM.
    Diabetes, 1997, Volume: 46, Issue:1

    Topics: Apolipoproteins A; Biomarkers; Blood Glucose; Blood Pressure; Cerebrovascular Disorders; Cholesterol

1997
In vivo and in vitro evidence of an adenosine-mediated mechanism of calcium entry blocker activities.
    Angiology, 1989, Volume: 40, Issue:3

    Topics: Adenosine; Arterial Occlusive Diseases; Calcium Channel Blockers; Dipyridamole; Female; Flunarizine;

1989