dipyridamole has been researched along with Hypoxia in 86 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twelve healthy young men took part in this investigation of the effect of oral theophylline and dipyridamole (two drugs known to affect the pharmacological effects of the purine nucleoside adenosine) on the respiratory response to isocapnic hypoxia." | 9.07 | Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects. ( Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST, 1991) |
| "Based on the hypothesis that blood platelets contribute to the pathogenesis of hypoxemic pulmonary hypertension in patients with chronic obstructive pulmonary disease (COPD), the effect of a prolonged treatment with dipyridamole, a platelet-inhibiting drug, on hypoxemic pulmonary hypertension was evaluated in a double-blind cross-over study." | 9.06 | Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease. ( Berrettini, M; Costantini, V; Nenci, GG; Parise, P; Todisco, T, 1988) |
| "The effect of hypoxia on the release of adenosine was studied in vitro in the rat whole carotid body (CB) and compared with the effect of hypoxia (2%, 5% and 10% O(2)) on adenosine concentrations in superior cervical ganglia (SCG) and carotid arteries." | 7.72 | Hypoxia induces adenosine release from the rat carotid body. ( Conde, SV; Monteiro, EC, 2004) |
| "Adenosine, a purine nucleoside, plays a variety of roles in cardiovascular and ventilatory control, and may be a marker of tissue hypoxia." | 7.70 | Plasma concentration of adenosine during normoxia and moderate hypoxia in humans. ( Kawakami, Y; Makita, H; Miyamoto, K; Nishimura, M; Saito, H; Sato, F; Shibuya, E; Shinano, H; Tsujino, I, 1999) |
| "We measured the changes in pial arteriolar diameter and CSF concentrations of adenosine, inosine, and hypoxanthine during hypoxia in the absence and presence of topically applied dipyridamole (10(-6) M) and erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA; 10(-5) M)." | 7.68 | Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia. ( Meno, JR; Ngai, AC; Winn, HR, 1993) |
| "The purpose of this study was to determine the effects of acute hypoxia on the ATP content of, and release of adenosine from, cultured endothelial cells." | 7.67 | Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. ( Berne, RM; Rubio, R; Shryock, JC, 1988) |
| "Pretreatment with dipyridamole blunted the increase in Ppa and Rp/Rs during repeat hypoxia, keeping Ppa at a subsystemic level and Rp/Rs < 1." | 5.30 | Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. ( Abman, SH; Clarke, WR; Ivy, DD; Kinsella, JP; Wiggins, JW; Ziegler, JW, 1998) |
| "The purine nucleoside, adenosine, has been implicated as a neuromodulator in central respiratory depression during prolonged exposure to hypoxia." | 5.08 | The effect of dipyridamole and theophylline on hypercapnic ventilatory responses: the role of adenosine. ( Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST, 1997) |
| "To examine the role of endogenous adenosine in hypoxic ventilatory response, we measured, in nine normal young adults, ventilatory responses to isocapnic progressive hypoxia and subsequent sustained hypoxia [arterial O2 saturation (SaO2); 80%, 20 min] with and without pretreatment with dipyridamole in a double-blind crossover fashion." | 5.07 | Role of endogenous adenosine in hypoxic ventilatory response in humans: a study with dipyridamole. ( Akiyama, Y; Kawakami, Y; Kobayashi, S; Miyamoto, K; Nishimura, M; Yamamoto, M, 1994) |
| " Twelve healthy young men took part in this investigation of the effect of oral theophylline and dipyridamole (two drugs known to affect the pharmacological effects of the purine nucleoside adenosine) on the respiratory response to isocapnic hypoxia." | 5.07 | Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects. ( Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST, 1991) |
| "Based on the hypothesis that blood platelets contribute to the pathogenesis of hypoxemic pulmonary hypertension in patients with chronic obstructive pulmonary disease (COPD), the effect of a prolonged treatment with dipyridamole, a platelet-inhibiting drug, on hypoxemic pulmonary hypertension was evaluated in a double-blind cross-over study." | 5.06 | Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease. ( Berrettini, M; Costantini, V; Nenci, GG; Parise, P; Todisco, T, 1988) |
| "Using a rat model of cerebral ischemia, the ENT1 inhibitor nitrobenzylmercaptopurine ribonucleoside (NBMPR) significantly increased post-ischemic forebrain adenosine levels and significantly decreased hippocampal neuron injury relative to saline-treatment." | 3.73 | Astrocytes and neurons: different roles in regulating adenosine levels. ( Parkinson, FE; Xiong, W; Zamzow, CR, 2005) |
| "The effect of hypoxia on the release of adenosine was studied in vitro in the rat whole carotid body (CB) and compared with the effect of hypoxia (2%, 5% and 10% O(2)) on adenosine concentrations in superior cervical ganglia (SCG) and carotid arteries." | 3.72 | Hypoxia induces adenosine release from the rat carotid body. ( Conde, SV; Monteiro, EC, 2004) |
| "Adenosine, a purine nucleoside, plays a variety of roles in cardiovascular and ventilatory control, and may be a marker of tissue hypoxia." | 3.70 | Plasma concentration of adenosine during normoxia and moderate hypoxia in humans. ( Kawakami, Y; Makita, H; Miyamoto, K; Nishimura, M; Saito, H; Sato, F; Shibuya, E; Shinano, H; Tsujino, I, 1999) |
| "The role of intracerebral adenosine levels in the control of ventilatory response to hypoxia was explored in 15 spontaneously breathing intubated piglets, 1-5 days old, sedated with chloral hydrate." | 3.69 | Role of adenosine in the hypoxic ventilatory response of the newborn piglet. ( Aranda, JV; Davis, GM; Lopes, JM; Mullahoo, K, 1994) |
| "In the present study, we have investigated the possible role of adenosine in the hypoxia-mediated increase in adenosine 3',5'-cyclic monophosphate (cAMP) in the carotid body." | 3.69 | cAMP production in rabbit carotid body: role of adenosine. ( Chen, J; Dinger, B; Fidone, SJ, 1997) |
| "We measured the changes in pial arteriolar diameter and CSF concentrations of adenosine, inosine, and hypoxanthine during hypoxia in the absence and presence of topically applied dipyridamole (10(-6) M) and erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA; 10(-5) M)." | 3.68 | Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia. ( Meno, JR; Ngai, AC; Winn, HR, 1993) |
| "The purpose of this study was to determine the effects of acute hypoxia on the ATP content of, and release of adenosine from, cultured endothelial cells." | 3.67 | Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. ( Berne, RM; Rubio, R; Shryock, JC, 1988) |
| "Data are reviewed describing hypoxemia, a newly identified feature in thalassemia." | 2.38 | Hypoxemia in thalassemia. ( Bunyaratvej, A; Chantaraksri, U; Fucharoen, S; Piankijagum, A; Siritanaratkul, N; Sonakul, D; Wasi, P; Winichagoon, P, 1992) |
| "Pretreatment with dipyridamole blunted the increase in Ppa and Rp/Rs during repeat hypoxia, keeping Ppa at a subsystemic level and Rp/Rs < 1." | 1.30 | Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. ( Abman, SH; Clarke, WR; Ivy, DD; Kinsella, JP; Wiggins, JW; Ziegler, JW, 1998) |
| "Treatment with theophylline did not alter the elevation of plasma [ADO] after dipyridamole infusion, but abolished responses of fetal heart rate to dipyridamole infusion." | 1.28 | Plasma adenosine and cardiovascular responses to dipyridamole in fetal sheep. ( Power, GG; Yoneyama, Y, 1992) |
| "Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue." | 1.27 | Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia. ( Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS, 1986) |
| "Dipyridamole did not produce any significant effect on phosphate metabolism in anoxic myocardium." | 1.26 | Effects of propranolo, itramin tosylate and dipyridamole on myocardial phosphate metabolism in anoxic perfused rat hearts. ( Takenaka, F; Umeda, T, 1976) |
| "Although anoxia releases noradrenaline from the heart the effect of anoxia on the VFT was not prevented by beta-adrenoceptor blockade with propranolol or pindolol or by previous treatment with reserpine." | 1.25 | The effect of anoxia on the ventricular fibrillation threshold in the rabbit isolated heart. ( Murnaghan, MF, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (72.09) | 18.7374 |
| 1990's | 21 (24.42) | 18.2507 |
| 2000's | 3 (3.49) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shih, WJ | 1 |
| Li, CY | 1 |
| Kiefer, V | 1 |
| NEUHAUS, G | 1 |
| LERCHE, D | 1 |
| SCHUCK, P | 1 |
| FRIMMER, M | 1 |
| HEGNER, D | 1 |
| WINKELMANN, W | 1 |
| BETZ, E | 1 |
| BENZING, H | 1 |
| KNOCHE, H | 1 |
| SCHMITT, G | 2 |
| CHIBA, T | 1 |
| LOVE, WD | 1 |
| TYLER, MD | 1 |
| ABRAHAM, RE | 1 |
| MUNFORD, RS | 1 |
| EKESTROEM, S | 1 |
| PALEUS, S | 1 |
| ABERG, T | 1 |
| Conde, SV | 1 |
| Monteiro, EC | 1 |
| Parkinson, FE | 1 |
| Xiong, W | 1 |
| Zamzow, CR | 1 |
| Nenci, GG | 3 |
| Berrettini, M | 2 |
| Todisco, T | 2 |
| Parise, P | 2 |
| Phillis, JW | 2 |
| Preston, G | 1 |
| DeLong, RE | 1 |
| Fucharoen, S | 2 |
| Youngchaiyud, P | 1 |
| Wasi, P | 2 |
| Donaghy, KM | 1 |
| Scholfield, CN | 1 |
| Igarashi, T | 1 |
| Nishimura, M | 4 |
| Akiyama, Y | 2 |
| Yamamoto, M | 3 |
| Miyamoto, K | 4 |
| Kawakami, Y | 4 |
| Kobayashi, S | 2 |
| Nasuhara, Y | 1 |
| Lopes, JM | 1 |
| Davis, GM | 1 |
| Mullahoo, K | 1 |
| Aranda, JV | 1 |
| Ran, PX | 1 |
| Duan, SF | 1 |
| Meno, JR | 1 |
| Ngai, AC | 1 |
| Winn, HR | 1 |
| Hofer, M | 1 |
| Pospísil, M | 1 |
| Netíková, J | 1 |
| Znojil, V | 1 |
| Vácha, J | 1 |
| Holá, J | 1 |
| Griffiths, TL | 2 |
| Christie, JM | 2 |
| Parsons, ST | 2 |
| Holgate, ST | 2 |
| Chen, J | 1 |
| Dinger, B | 1 |
| Fidone, SJ | 1 |
| Gleiter, CH | 2 |
| Brause, M | 1 |
| Delabar, U | 1 |
| Zebski, H | 1 |
| Eckardt, KU | 1 |
| Becker, T | 1 |
| Wenzel, J | 1 |
| Ziegler, JW | 1 |
| Ivy, DD | 1 |
| Wiggins, JW | 1 |
| Kinsella, JP | 1 |
| Clarke, WR | 1 |
| Abman, SH | 1 |
| Saito, H | 1 |
| Shinano, H | 1 |
| Makita, H | 1 |
| Tsujino, I | 1 |
| Shibuya, E | 1 |
| Sato, F | 1 |
| Takenaka, F | 1 |
| Umeda, T | 1 |
| Degenring, FH | 1 |
| Curnish, RR | 1 |
| Rubio, R | 2 |
| Berne, RM | 3 |
| Heckeroth, VA | 1 |
| Michel, CF | 1 |
| Benzi, G | 2 |
| Mlczoch, J | 1 |
| Weir, EK | 1 |
| Grover, RF | 1 |
| Coeugniet, E | 1 |
| Murnaghan, MF | 1 |
| Luque, J | 1 |
| Pinilla, M | 1 |
| Monfort, R | 2 |
| Aznar, J | 1 |
| Alemany, JR | 1 |
| Winichagoon, P | 1 |
| Siritanaratkul, N | 1 |
| Sonakul, D | 1 |
| Chantaraksri, U | 1 |
| Bunyaratvej, A | 1 |
| Piankijagum, A | 1 |
| Yoneyama, Y | 1 |
| Power, GG | 1 |
| O'Regan, MH | 1 |
| Perkins, LM | 1 |
| Froldi, G | 1 |
| Belardinelli, L | 2 |
| Milusheva, E | 1 |
| Sperlágh, B | 1 |
| Kiss, B | 1 |
| Szporny, L | 1 |
| Pásztor, E | 1 |
| Papasova, M | 1 |
| Vizi, ES | 1 |
| Keith, IM | 1 |
| Will, JA | 1 |
| Huxtable, RJ | 1 |
| Weir, K | 1 |
| Barrett, JA | 1 |
| DePaul Lynch, V | 1 |
| Balkon, J | 1 |
| Smith, RD | 1 |
| Wolf, PS | 1 |
| Watanabe, K | 1 |
| Kimura, Y | 1 |
| Abiko, Y | 3 |
| Shryock, JC | 1 |
| Decking, UK | 1 |
| Juengling, E | 1 |
| Kammermeier, H | 1 |
| Costantini, V | 1 |
| McIlwain, H | 1 |
| Poll, JD | 1 |
| Arrigoni, E | 1 |
| Manzo, L | 1 |
| De Bernardi, M | 1 |
| Ferrara, A | 1 |
| Panceri, P | 1 |
| Berte, F | 1 |
| Virtanen, KS | 1 |
| Meisel, M | 1 |
| Meisel, P | 1 |
| Urbaszek, W | 1 |
| Tronicke, E | 1 |
| Modersohn, D | 1 |
| Uhlich, C | 1 |
| Günther, K | 1 |
| Pankau, H | 1 |
| Duchène-Marullaz, P | 1 |
| Cosnier, D | 1 |
| Perriere, JP | 1 |
| Hache, J | 1 |
| Juhran, W | 1 |
| Voss, EM | 1 |
| Dietmann, K | 1 |
| Schaumann, W | 1 |
| Swan, H | 1 |
| Meagher, DM | 1 |
| Wussling, M | 1 |
| Szymanski, G | 1 |
| Schrör, K | 1 |
| Minamidate, A | 1 |
| Takano, S | 2 |
| Hashikawa, T | 2 |
| Hayashi, A | 1 |
| Haas, H | 1 |
| Gokel, M | 1 |
| Wadsworth, RM | 2 |
| Matthys, H | 2 |
| Rühle, KH | 2 |
| Schilling, M | 2 |
| Freitag, M | 2 |
| Konietzko, N | 2 |
| Schlehe, H | 2 |
| Kleeberg, UR | 2 |
| Parratt, JR | 1 |
| Merchant, FJ | 1 |
| Feinberg, H | 1 |
| Levitsky, S | 1 |
| Schoen, HR | 1 |
| Gerlach, E | 1 |
| Deuticke, B | 1 |
| Rosenkrantz, JG | 2 |
| Lynch, FP | 2 |
| Vogel, JH | 2 |
| Kukovetz, WR | 1 |
| Pöch, G | 1 |
| Bassenge, E | 1 |
| Walter, P | 1 |
| Doutheil, U | 1 |
| Doll, E | 1 |
| Keul, J | 1 |
| Lemieux, VP | 1 |
| Gowdey, CW | 1 |
| Philp, RB | 1 |
| Gutiérrez Goicoechea, JM | 1 |
| Hauss, W | 1 |
| Kontos, HA | 1 |
| Goldin, D | 1 |
| Richardson, DW | 1 |
| Patterson, JL | 1 |
| Diesfeld, HJ | 1 |
| López-Campos, JL | 1 |
| Vega Cid, J | 1 |
| Rosa, LM | 1 |
| Kusukawa, R | 1 |
| MacCanon, DM | 1 |
| Kisch, B | 1 |
| Kraupp, O | 1 |
| Keegan, DJ | 1 |
| Webster, I | 1 |
| Belmonte, A | 1 |
| Lozada, BB | 1 |
| Laguens, RP | 1 |
5 reviews available for dipyridamole and Hypoxia
| Article | Year |
|---|---|
[ON CHEMO- AND PRESSOR RECEPTOR FIELDS IN THE CORONARY CIRCULATION].
Topics: Anemia; Animals; Cats; Child; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs; Electrons; | 1963 |
A case of pulmonary AV fistula. Possible involvement of adenosine in hyperventilation.
Topics: Adenosine; Adult; Aminophylline; Arteriovenous Fistula; Combined Modality Therapy; Dipyridamole; Hum | 1994 |
Hypoxemia in thalassemia.
Topics: Aspirin; Blood Gas Analysis; Dipyridamole; Follow-Up Studies; Heart Failure; Humans; Hypoxia; Platel | 1992 |
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide; | 1974 |
[Comparative animal experiment studies of the prolongation of the revival time of the heart and the whole organ in normothermia by pharmacological pretreatment].
Topics: Adenine Nucleotides; Anesthesia, General; Animals; Cardiac Surgical Procedures; Chromatography, Pape | 1968 |
8 trials available for dipyridamole and Hypoxia
| Article | Year |
|---|---|
Enhanced plasma beta-thromboglobulin in hypoxemia: effect of dipyridamole.
Topics: Aged; Beta-Globulins; beta-Thromboglobulin; Clinical Trials as Topic; Dipyridamole; Female; Humans; | 1981 |
Effect of aminophylline on plasma [K+] and hypoxic ventilatory response during mild exercise in men.
Topics: Adolescent; Adult; Aminophylline; Catecholamines; Chromatography, High Pressure Liquid; Dipyridamole | 1994 |
Role of endogenous adenosine in hypoxic ventilatory response in humans: a study with dipyridamole.
Topics: Adenosine; Adult; Carbon Dioxide; Dipyridamole; Double-Blind Method; Humans; Hypoxia; Infusions, Int | 1994 |
The effect of dipyridamole and theophylline on hypercapnic ventilatory responses: the role of adenosine.
Topics: Adenosine; Administration, Oral; Adult; Analysis of Variance; Bronchodilator Agents; Carbon Dioxide; | 1997 |
Erythropoietin production in healthy volunteers subjected to controlled hypobaric hypoxia: further evidence against a role for adenosine.
Topics: Adenosine; Adult; Area Under Curve; Atmosphere Exposure Chambers; Dipyridamole; Erythropoietin; Huma | 1997 |
[Mechanism of ventilatory and heart-rate responses during sustained hypoxia in humans--role of endogenous adenosine].
Topics: Adenosine; Adult; Cross-Over Studies; Dipyridamole; Double-Blind Method; Heart Rate; Humans; Hypoxia | 1997 |
Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects.
Topics: Adenosine; Adult; Carbon Dioxide; Computers; Dipyridamole; Double-Blind Method; Humans; Hypoxia; Mal | 1991 |
Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease.
Topics: Aged; Blood Pressure; Dipyridamole; Humans; Hypertension, Pulmonary; Hypoxia; Lung Diseases, Obstruc | 1988 |
73 other studies available for dipyridamole and Hypoxia
| Article | Year |
|---|---|
Significance of the visualization of bone marrow during dipyridamole Tc-99m tetrofosmin myocardial and gated SPECT.
Topics: Aged; Anemia; Bone Marrow; Chest Pain; Dipyridamole; Emphysema; Female; Gated Blood-Pool Imaging; He | 2002 |
[The hypoxia test in evaluation of coronary-active drugs, especially of persantin in man].
Topics: Cardiovascular Agents; Coronary Vessels; Dipyridamole; Hypoxia; Vasodilator Agents | 1961 |
[The effect of 2,6-bis (diethanolamino)-4,8-dipiperidino-pyrimido-(5,4-d)-pyrimidine (Persantin) on the respiration of mitochondria in low O2 pressure].
Topics: Cell Respiration; Dipyridamole; Electron Transport Complex II; Humans; Hypoxia; Liver; Metabolism; M | 1963 |
[ON THE MECHANISM OF ACTION OF 2,6-BIS(DIETHANOLAMINO)-4,8-DIPIPERIDINOPYRIMIDO(5,4-D)PYRIMIDINE ON MYOCARDIAL CIRCULATION].
Topics: Blood Circulation; Cats; Dipyridamole; Hypoxia; Muscles; Myocardium; Pharmacology; Pyrimidines; Rese | 1963 |
EXPERIMENTAL STUDIES ON THE EFFECTS OF PERSANTIN WITH NORMAL AND GO-DOGS.
Topics: Coronary Disease; Dipyridamole; Dogs; Hypoxia; Pathology; Pharmacology; Research | 1963 |
EFFECTS OF O2,CO2, AND DRUGS ON ESTIMATING CORONARY BLOOD FLOW FROM RB86 CLEARANCE.
Topics: Animals; Blood Circulation; Blood Gas Analysis; Carbon Dioxide; Coronary Vessels; Digitoxin; Dipyrid | 1965 |
[BIOCHEMICAL AND PHYSIOLOGIC STUDIES ON THE ANOXIC DOG HEART WITH EXTRACORPOREAL CIRCULATION WITH AND WITHOUT ADMINISTRATION OF PERSANTIN (2,6-BIS(DIETHANOLAMINO)-4,8-DIPIPERIDINO-PYRIMIDO-(5,4-D)PYRIDINE)].
Topics: Adenosine Triphosphate; Blood; Dipyridamole; Dogs; Extracorporeal Circulation; Heart; Heart Function | 1965 |
Hypoxia induces adenosine release from the rat carotid body.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Carotid Body; Carrier Proteins; Chemorec | 2004 |
Astrocytes and neurons: different roles in regulating adenosine levels.
Topics: Adenosine; Affinity Labels; Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Deoxyglucose; Dipy | 2005 |
Platelets, hypoxemia and pulmonary hypertension.
Topics: Blood Platelets; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Humans; Hypertension, Pulmon | 1984 |
Effects of anoxia on cerebral blood flow in the rat brain: evidence for a role of adenosine in autoregulation.
Topics: Adenosine; Animals; Brain; Caffeine; Cerebrovascular Circulation; Dipyridamole; Homeostasis; Hypoxia | 1984 |
Hypoxaemia and the effect of aspirin in thalassaemia.
Topics: Adolescent; Adult; Aspirin; Dipyridamole; Female; Humans; Hypoxia; Male; Middle Aged; Splenectomy; T | 1981 |
Concentration dependence of adenosine and the protection of rat cortical neurones during anoxia.
Topics: Adenosine; Adenosine Deaminase; Animals; Dipyridamole; Evoked Potentials; Hypoxia; In Vitro Techniqu | 1994 |
Role of adenosine in the hypoxic ventilatory response of the newborn piglet.
Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Cerebrospinal Fluid; Citrates; Dipyridamole; Drug Co | 1994 |
[The effects of persantine on pulmonary arterial pressure of rats exposed to hypoxia].
Topics: Animals; Blood Pressure; Dipyridamole; Hypertension, Pulmonary; Hypoxia; Male; Rats; Rats, Sprague-D | 1993 |
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hy | 1993 |
Radioprotective efficacy of dipyridamole and AMP combination in fractionated radiation regimen, and its dependence on the time of administration of the drugs prior to irradiation.
Topics: Adenosine Monophosphate; Animals; Body Weight; Cell Division; Dipyridamole; Drug Administration Sche | 1995 |
cAMP production in rabbit carotid body: role of adenosine.
Topics: Adenosine; Animals; Carotid Body; Cyclic AMP; Dipyridamole; Hypoxia; In Vitro Techniques; Phenethyla | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyri | 1997 |
Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension.
Topics: Administration, Inhalation; Adolescent; Adult; Aorta; Blood Pressure; Bronchodilator Agents; Cardiac | 1998 |
Plasma concentration of adenosine during normoxia and moderate hypoxia in humans.
Topics: Adenosine; Arteries; Chromatography, High Pressure Liquid; Dipyridamole; Humans; Hypoxia; Male; Oxyg | 1999 |
Effects of propranolo, itramin tosylate and dipyridamole on myocardial phosphate metabolism in anoxic perfused rat hearts.
Topics: Adrenergic beta-Antagonists; Anaerobiosis; Animals; Dipyridamole; Ethylamines; Heart; Heart Rate; Hy | 1976 |
Effect of dipyridamole on myocardial adenosine metabolism and coronary flow in hypoxia and reactive hyperemia in the isolated perfused guinea pig heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiome | 1976 |
[The effect of various substances on the time of survival of rabbits under conditiones of oxygen-delay (author's transl)].
Topics: Acid-Base Equilibrium; Acidosis; Actihaemyl; Animals; Asphyxia; Blood Gas Analysis; Dipyridamole; Fe | 1977 |
An analysis of the drugs acting on cerebral energy metabolism.
Topics: Adenine Nucleotides; Amobarbital; Animals; Bemegride; Brain; Dipyridamole; Dogs; Energy Metabolism; | 1975 |
Inhibition of hypoxic pulmonary vasoconstriction by dipyridamole is not platelet mediated.
Topics: Animals; Blood Platelets; Blood Pressure; Dipyridamole; Dogs; Female; Hypoxia; Immune Sera; Lung; Ma | 1977 |
Drugs with antithrombotic effect: experimental study.
Topics: Animals; Aspirin; Dipyridamole; Drug Synergism; Heparin; Hypoxia; Lysine; Mice; Platelet Aggregation | 1976 |
The effect of anoxia on the ventricular fibrillation threshold in the rabbit isolated heart.
Topics: Adenosine; Animals; Dipyridamole; Electrocardiography; Heart; Heart Rate; Hypoxia; In Vitro Techniqu | 1975 |
In vivo influence of dipyridamole and KCN on 2,3-diphosphoglycerate levels in hamsters.
Topics: Animals; Cricetinae; Cyanates; Diphosphoglyceric Acids; Dipyridamole; Erythrocytes; Hypoxia; Injecti | 1976 |
Plasma adenosine and cardiovascular responses to dipyridamole in fetal sheep.
Topics: Adenosine; Animals; Blood Pressure; Dipyridamole; Female; Fetus; Gestational Age; Heart Rate, Fetal; | 1992 |
Measurement of rat plasma adenosine levels during normoxia and hypoxia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Blood Pressure; Carbon Dioxide; Chromatography | 1992 |
Species-dependent effects of adenosine on heart rate and atrioventricular nodal conduction. Mechanism and physiological implications.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Atrioventricular Node; Bundle of His; D | 1990 |
Inhibitory effect of hypoxic condition on acetylcholine release is partly due to the effect of adenosine released from the tissue.
Topics: Acetylcholine; Adenosine; Animals; Dipyridamole; Female; Guinea Pigs; Hypoxia; In Vitro Techniques; | 1990 |
Anti-platelet agents reduce morphological changes of chronic hypoxic pulmonary hypertension.
Topics: Animals; Dipyridamole; Flunarizine; Heart; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Male; | 1987 |
Effects of hypoxia and ischaemia on coronary vascular resistance, A-V node conduction and S-A node excitation.
Topics: Adenine Nucleotides; Adenosine; Aminophylline; Atrioventricular Node; Coronary Circulation; Coronary | 1985 |
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dog | 1986 |
Nifedipine increases oxygen saturation level of myoglobin in the rat heart during hypoxia.
Topics: Animals; Dipyridamole; Heart; Hypoxia; Male; Myocardium; Myoglobin; Nifedipine; Nitroglycerin; Rats; | 1986 |
Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Cells, Cultured; Dipyridamole; Endothelium, Vascu | 1988 |
Interstitial transudate concentration of adenosine and inosine in rat and guinea pig hearts.
Topics: Adenosine; Animals; Coformycin; Coronary Circulation; Dipyridamole; Exudates and Transudates; Guinea | 1988 |
Adenosine in cerebral homeostatic role: appraisal through actions of homocysteine, colchicine, and dipyridamole.
Topics: Adenine; Adenosine; Animals; Cerebral Cortex; Colchicine; Dipyridamole; Glutamates; Guinea Pigs; Hom | 1986 |
Estimation of changes induced by drugs in cerebral energy-coupling processes in situ in the dog.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Anesthesia; Animals; Bemegride; Brain; Bromine | 1973 |
Phasic myocardial blood content. An experimental study on effects of hypoxaemia, ischaemia and coronary drugs.
Topics: Animals; Anti-Arrhythmia Agents; Biopsy; Cardiac Output; Chromium Radioisotopes; Coronary Circulatio | 1974 |
[Effects of coronary vaso dilators on myocardial survival time in the rat under anoxia conditions].
Topics: Animals; Coronary Circulation; Dipyridamole; Female; Heart; Hypoxia; Male; Myocardium; Nitroglycerin | 1974 |
[Tentative evaluation of the antianoxic capiacity of dipyridamole and piridoxilate].
Topics: Anesthesia, General; Animals; Cyanides; Dipyridamole; Dogs; Glycolates; Guinea Pigs; Hypoxia | 1968 |
Pharmacological effects on coronary reactive hyperemia in conscious dogs.
Topics: Animals; Coronary Disease; Coronary Vessels; Coumarins; Dipyridamole; Dogs; Drug Synergism; Glycolat | 1971 |
Total body bypass in miniature pigs. Postperfusion pulmonary hypertension.
Topics: Acidosis; Anesthesia, Inhalation; Animals; Blood Group Incompatibility; Blood Pressure; Capillary Pe | 1971 |
The influence of hypertrophy and hypoxia on potentiation phenomena of the rabbit papillary muscle tested by a double rest programme.
Topics: Animals; Aortic Valve Stenosis; Calcium; Cardiomegaly; Dipyridamole; Electric Stimulation; Heart Ven | 1974 |
Transmural gradient of NAD-NADPH ratio in their canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient.
Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; Myocardium; | 1973 |
Redox state of nicotinamide-adenine dinucleotide in the inner and outer layers of canine left ventricle, and effects of coronary dilators on the redox state.
Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; NAD; Nitrogl | 1974 |
[Effect of Verapamil on the metabolism of myocardium].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Asphyxia; Blood Glucos | 1970 |
Anti-anginal drugs and the vasodilator response to myocardial hypoxia.
Topics: Angina Pectoris; Animals; Cats; Collateral Circulation; Coronary Circulation; Dipyridamole; Drug Syn | 1971 |
[Proceedings: Effect of dipyridamole and acute hypoxia on oxygen-binding capacity of hemoglobin in normal persons].
Topics: Blood Pressure; Cardiac Volume; Dipyridamole; Hemoglobins; Humans; Hypoxia; Lung; Oxygen Consumption | 1974 |
The effects of dipyridamole on coronary post-occlusion hyperaemia and on myocardial vasodilatation induced by systemic hypoxia.
Topics: Animals; Benzoates; Blood Pressure; Catheterization; Cats; Coronary Vessels; Dipyridamole; Electroca | 1972 |
Reversal of myocardial depression by dipyridamole following aortic cross-clamping.
Topics: Animals; Aorta; Depression, Chemical; Dipyridamole; Dogs; Heart; Heart Arrest; Hypoxia | 1972 |
Adaptation of the oxygen affinity of haemoglobin in acute hypoxia.
Topics: Adaptation, Biological; Adolescent; Adult; Dipyridamole; Hemoglobins; Humans; Hydrogen-Ion Concentra | 1974 |
[Comparative studies on the formation of adenosine in the myocardium of different animal species in oxygen deficiency].
Topics: Adenine Nucleotides; Aminohydrolases; Animals; Cats; Dipyridamole; Dogs; Guinea Pigs; Haplorhini; He | 1966 |
Hypoxic pulmonary hypertension: its modification by dipyridamole.
Topics: Animals; Blood Pressure; Cardiac Catheterization; Cardiac Output; Dipyridamole; Hemodynamics; Hypert | 1972 |
Inhibition of hypoxia-induced rise in adenosine release and flow by coronary dilators.
Topics: Adenosine; Animals; Carbon Isotopes; Coronary Circulation; Coronary Vessels; Dipyridamole; Guinea Pi | 1971 |
[Reversal of the effect of the adrenergic coronary vascular reaction in dependence upon the coronary vascular tonus].
Topics: Animals; Blood Flow Velocity; Coronary Vessels; Dipyridamole; Dogs; Epinephrine; Hypoxia; Isoprotere | 1967 |
[Coronary reserve in man].
Topics: Carbon Dioxide; Coronary Vessels; Dipyridamole; Heart; Hemodynamics; Humans; Hydrogen-Ion Concentrat | 1969 |
Pulmonary hypertension: treatment by drugs which modify intravascular aggregation.
Topics: Animals; Blood Platelets; Dipyridamole; Hypertension, Pulmonary; Hypoxia; Swine | 1969 |
Effects of dipyridamole and nitroprusside on the oxygen paradox and reactive hyperemia.
Topics: Animals; Blood Pressure; Carotid Arteries; Cats; Dipyridamole; Femoral Artery; Ferricyanides; Hypere | 1970 |
[Resistance of the myocardium in anoxia].
Topics: Anesthesia, Inhalation; Animals; Dipyridamole; Dogs; Electrocardiography; Ethyl Ethers; Halothane; H | 1971 |
[On the protective action of coronary vessel collaterals].
Topics: Animals; Arteries; Collateral Circulation; Coronary Vessels; Dipyridamole; Hypertension; Hypoxia; Ra | 1967 |
Effect of dipyridamole on vasodilator responses to ischemia, hypoxia, ATP, and AMP.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Blood Vessels; Dipyridamole; D | 1968 |
[Prophylaxis and therapy of altitude adaptation disturbances with Persantin].
Topics: Altitude; Dipyridamole; Humans; Hypoxia | 1968 |
[Changes of ATP-ase activity in the heart muscle of the rat in anoxia conditions].
Topics: Adenosine Triphosphate; Animals; Dipyridamole; Heart; Hypoxia; Myocardium; Rats | 1968 |
Myocardial tolerance to discontinous hypoxia in guinea pigs.
Topics: Animals; Coronary Disease; Dipyridamole; Electrocardiography; Guinea Pigs; Hypoxia; In Vitro Techniq | 1965 |
Testing the sarcosome protecting power of certain drugs.
Topics: Animals; Digitoxin; Dipyridamole; Heart Diseases; Hypoxia; Mitochondria; Mitochondria, Muscle; Oxyge | 1965 |
[Pharmacotherapy of states of deficient myocardial circulation. Pharmacologic aspects].
Topics: Anti-Arrhythmia Agents; Dipyridamole; Humans; Hypoxia; Myocardium; Papaverine; Phenobarbital; Vasodi | 1965 |
Preliminary experiments on the effect of Persantin on the animal heart.
Topics: Animals; Cats; Coronary Vessels; Dipyridamole; Electrocardiography; Guinea Pigs; Heart; Heart Functi | 1966 |
[Pharmacological protection against hypercapnic anoxemic anoxia caused by experimental submersion. The role of dipyridamole and of glucose].
Topics: Animals; Dipyridamole; Diving; Glucose; Heart; Hypoxia; Mice | 1966 |
Hypoxia and the heart ultrastructure with special reference to the protective action of the coronary drug Persantin.
Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Hypoxia; Microscopy, Electron; Mitochondria; Myocardi | 1966 |