dipyridamole has been researched along with Hyperplasia in 9 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effects of cod-liver oil and a combination of cod-liver oil and dipyridamole on vein-graft intimal hyperplasia, 76 segments of undistended jugular vein were interposed between bilaterally divided femoral arteries in 38 mongrel dogs who received a 2% cholesterol diet." | 7.67 | Reduction of intimal hyperplasia in canine autologous vein grafts with cod-liver oil and dipyridamole. ( Cameron, CA; Landymore, RW; MacAuley, MA; Sheridan, BL, 1986) |
| "The combination of aspirin and dipyridamole is currently used to prevent intimal hyperplasia and to improve long-term vein graft patency following myocardial revascularization." | 7.67 | Comparison of cod-liver oil and aspirin-dipyridamole for the prevention of intimal hyperplasia in autologous vein grafts. ( Cameron, C; Landymore, RW; MacAulay, M; Sheridan, B, 1986) |
| "To determine the effects of cod-liver oil and a combination of cod-liver oil and dipyridamole on vein-graft intimal hyperplasia, 76 segments of undistended jugular vein were interposed between bilaterally divided femoral arteries in 38 mongrel dogs who received a 2% cholesterol diet." | 3.67 | Reduction of intimal hyperplasia in canine autologous vein grafts with cod-liver oil and dipyridamole. ( Cameron, CA; Landymore, RW; MacAuley, MA; Sheridan, BL, 1986) |
| "The combination of aspirin and dipyridamole is currently used to prevent intimal hyperplasia and to improve long-term vein graft patency following myocardial revascularization." | 3.67 | Comparison of cod-liver oil and aspirin-dipyridamole for the prevention of intimal hyperplasia in autologous vein grafts. ( Cameron, C; Landymore, RW; MacAulay, M; Sheridan, B, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weale, AR | 1 |
| Cooper, DG | 1 |
| Kuji, T | 1 |
| Masaki, T | 1 |
| Goteti, K | 1 |
| Li, L | 1 |
| Zhuplatov, S | 1 |
| Terry, CM | 1 |
| Zhu, W | 1 |
| Leypoldt, JK | 1 |
| Rathi, R | 1 |
| Blumenthal, DK | 1 |
| Kern, SE | 1 |
| Cheung, AK | 1 |
| McCann, RL | 1 |
| Hagen, PO | 2 |
| Fuchs, JC | 1 |
| Wang, ZG | 1 |
| Mikat, EM | 1 |
| Hackel, DB | 1 |
| Oblath, RW | 1 |
| Buckley, FO | 1 |
| Green, RM | 1 |
| Schwartz, SI | 1 |
| DeWeese, JA | 1 |
| Landymore, RW | 2 |
| Cameron, CA | 1 |
| Sheridan, BL | 1 |
| MacAuley, MA | 1 |
| Bourassa, MG | 1 |
| Fisher, LD | 1 |
| Campeau, L | 1 |
| Gillespie, MJ | 1 |
| McConney, M | 1 |
| Lespérance, J | 1 |
| Fuster, V | 1 |
| Chesebro, JJ | 1 |
| MacAulay, M | 1 |
| Sheridan, B | 1 |
| Cameron, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000489] | Phase 3 | 0 participants | Interventional | 1973-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dipyridamole and Hyperplasia
| Article | Year |
|---|---|
Long-term fate of bypass grafts: the Coronary Artery Surgery Study (CASS) and Montreal Heart Institute experiences.
Topics: Animals; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Dipyridamole; Follow-Up Studies; | 1985 |
Aortocoronary artery vein-graft disease: experimental and clinical approach for the understanding of the role of platelets and platelet inhibitors.
Topics: Animals; Aspirin; Blood Platelets; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Dogs; Gra | 1985 |
1 trial available for dipyridamole and Hyperplasia
| Article | Year |
|---|---|
Long-term fate of bypass grafts: the Coronary Artery Surgery Study (CASS) and Montreal Heart Institute experiences.
Topics: Animals; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Dipyridamole; Follow-Up Studies; | 1985 |
7 other studies available for dipyridamole and Hyperplasia
| Article | Year |
|---|---|
Dipyridamole plus aspirin and hemodialysis graft patency.
Topics: Aspirin; Blood Vessel Prosthesis; Dipyridamole; Drug Therapy, Combination; Graft Occlusion, Vascular | 2009 |
Efficacy of local dipyridamole therapy in a porcine model of arteriovenous graft stenosis.
Topics: Animals; Arteriovenous Shunt, Surgical; Carotid Arteries; Cell Proliferation; Delayed-Action Prepara | 2006 |
Aspirin and dipyridamole decrease intimal hyperplasia in experimental vein grafts.
Topics: Animals; Aspirin; Carotid Arteries; Dipyridamole; Femoral Vein; Haplorhini; Hyperplasia; Iliac Arter | 1980 |
Antiplatelet therapy reduces aortic intimal hyperplasia distal to small diameter vascular prostheses (PTFE) in nonhuman primates.
Topics: Animals; Aorta, Abdominal; Aortic Diseases; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Dipyr | 1982 |
Prevention of platelet aggregation and adherence to prosthetic vascular grafts by aspirin and dipyridamole.
Topics: Animals; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Dogs; Femoral Artery; Hyperplasia; Platelet | 1978 |
Reduction of intimal hyperplasia in canine autologous vein grafts with cod-liver oil and dipyridamole.
Topics: Animals; Blood Coagulation Tests; Cholesterol, Dietary; Cod Liver Oil; Dipyridamole; Dogs; Eicosapen | 1986 |
Comparison of cod-liver oil and aspirin-dipyridamole for the prevention of intimal hyperplasia in autologous vein grafts.
Topics: Animals; Aspirin; Blood Platelets; Cod Liver Oil; Dietary Fats; Dipyridamole; Dogs; Drug Combination | 1986 |