Page last updated: 2024-10-26

dipyridamole and Hyperlipidemias

dipyridamole has been researched along with Hyperlipidemias in 14 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Hyperlipidemias: Conditions with excess LIPIDS in the blood.

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's1 (7.14)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, RJ1
Albers, G1
Alberts, MJ1
Benavente, O1
Furie, K1
Goldstein, LB1
Gorelick, P1
Halperin, J1
Harbaugh, R1
Johnston, SC1
Katzan, I1
Kelly-Hayes, M1
Kenton, EJ1
Marks, M1
Sacco, RL1
Schwamm, LH1
Bollinger, A1
Biland, L1
Brunner, U1
Kappert, A1
Krähenbühl, B1
Mahler, F1
Monti, M1
Nachbur, B1
Schneider, E1
Widmer, LK1
Pyrig, LA1
Petrun, NM1
Nikulina, GG1
Gorelova, NR1
Bonchek, LI1
Boerboom, LE1
Olinger, GN1
Pepper, JR1
Munns, J1
Hutchinson, L1
Kissebah, AH1
Paredero Del Bosque Martin, V1
Yamada, M1
Omata, K1
Abe, F1
Ito, S1
Abe, K1
Bigi, R1
Desideri, A1
Cortigiani, L1
Bax, JJ1
Celegon, L1
Fiorentini, C1
Mustard, JF1
Packham, MA1
Kinlough-Rathbone, RL1
Zannino, L1
Salvadori, G1
Strano, A1
Novo, S1
O'Sullivan, DJ1
Lim, GH1
Darveniza, P1
Coffey, GL1
Hammerl, H1
Nebosis, G1
Pichler, O1
Studlar, M1
Goto, Y1
Nishino, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind Trial to Test Higher- Versus Lower-Doses of Aspirin on Inflammatory Markers and Platelet Biomarkers and Nitric Oxide Formation in High Risk Primary Prevention (Patients With Metabolic Syndrome)[NCT00272311]Phase 470 participants (Actual)Interventional2006-10-31Completed
A Randomized, Double-Blind Trial to Test Higher- Versus Lower-Doses of Aspirin on Inflammatory Markers and Platelet Biomarkers and Nitric Oxide Formation & Endothelial Function in Secondary Prevention (Pts w/Chronic Stable Coronary Disease)[NCT00272337]Phase 437 participants (Actual)Interventional2006-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Nitric Oxide Formation From Baseline to 3 Months

Changes in Heme oxygenase (HO-1) a downstream target of nitric oxide (NO) formation. (NCT00272311)
Timeframe: Baseline to 3 Months (90-97 days)

Interventionng/mL (Mean)
Arm 1 of 5 Randomized Treatment Arms27.6
Arm 2 of 5 Randomized Treatment Arms27.0
Arm 3 of 5 Randomized Treatment Arms31.4
Arm 4 of 5 Randomized Treatment Arms25.7
Arm 5 of 5 Randomized Treatment Arms28.3

Change in Nitric Oxide Formation From Baseline to 3 Months.

Heme oxygenase a downstream target of nitric oxide formation (NCT00272337)
Timeframe: Baseline to 3 Months (90-97 days)

Interventionng/mL (Mean)
1 of 5 Randomized Treatment Arms10.0
2 of 5 Randomized Treatment Arms11.2
3 of 5 Randomized Treatment Arms10.0
4 of 5 Randomized Treatment Arms11.0
5 of 5 Randomized Treatment Arms9.6

Reviews

3 reviews available for dipyridamole and Hyperlipidemias

ArticleYear
Platelets and thrombosis in the development of atherosclerosis and its complications.
    Advances in experimental medicine and biology, 1978, Volume: 102

    Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Dipyridamole; Endothelium; Human

1978
Platelets and thrombosis in the development of atherosclerosis and its complications.
    Advances in experimental medicine and biology, 1978, Volume: 102

    Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Dipyridamole; Endothelium; Human

1978
Platelets and thrombosis in the development of atherosclerosis and its complications.
    Advances in experimental medicine and biology, 1978, Volume: 102

    Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Dipyridamole; Endothelium; Human

1978
Platelets and thrombosis in the development of atherosclerosis and its complications.
    Advances in experimental medicine and biology, 1978, Volume: 102

    Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Dipyridamole; Endothelium; Human

1978
[Platelet aggregation inhibitors. Their possible use in pediatric pathology].
    Minerva pediatrica, 1979, Jan-31, Volume: 31, Issue:2

    Topics: Age Factors; Anti-Inflammatory Agents; Aspirin; Child; Clofibrate; Dextrans; Diabetes Mellitus, Type

1979
[Prospects of antiaggregant therapy in prevention of atherosclerosis].
    Giornale italiano di cardiologia, 1979, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Arteriosclerosis; Aspirin; Blood Coagulation Diso

1979

Other Studies

11 other studies available for dipyridamole and Hyperlipidemias

ArticleYear
Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack.
    Stroke, 2008, Volume: 39, Issue:5

    Topics: Aspirin; Brain Ischemia; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Combinations; Dru

2008
[Therapy of peripheral arterial occlusive diseases. Round table conference].
    Schweizerische medizinische Wochenschrift, 1983, Dec-10, Volume: 113, Issue:49

    Topics: Alprostadil; Angioplasty, Balloon; Anti-Bacterial Agents; Anticoagulants; Arterial Occlusive Disease

1983
Abnormalities of lipid metabolism and methods of their correction in patients with glomerulonephritis.
    International urology and nephrology, 1984, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Arteriosclerosis; Clofibrate; Dipyridamole; Female; Glomerulonephritis; Humans; H

1984
Prevention of lipid accumulation in experimental vein bypass grafts by antiplatelet therapy.
    Circulation, 1982, Volume: 66, Issue:2

    Topics: Animals; Arteriosclerosis; Aspirin; Coronary Artery Bypass; Dipyridamole; Hyperlipidemias; Lipid Met

1982
[Indications for surgical treatment and medical treatment of atherosclerosis].
    Minerva medica, 1980, Oct-20, Volume: 71, Issue:40

    Topics: Arteriosclerosis; Aspirin; Cholestyramine Resin; Clofibrate; Dextrothyroxine; Dipyridamole; Humans;

1980
Changes in prostacyclin, thromboxane A2 and F2-isoprostanes, and influence of eicosapentaenoic acid and antiplatelet agents in patients with hypertension and hyperlipidemia.
    Immunopharmacology, 1999, Oct-15, Volume: 44, Issue:1-2

    Topics: Aspirin; Dinoprost; Dipyridamole; Eicosapentaenoic Acid; Epoprostenol; Humans; Hyperlipidemias; Hype

1999
Stress echocardiography for risk stratification of diabetic patients with known or suspected coronary artery disease.
    Diabetes care, 2001, Volume: 24, Issue:9

    Topics: Adrenergic beta-Agonists; Age Factors; Aged; Coronary Disease; Diabetes Complications; Diabetes Mell

2001
Multiple progressive intracranial arterial occlusions ('moyamoya' disease).
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Antihypertensive Agents; Arterial Occlusive Diseases; Cerebral Angio

1977
[Influence of a combined treatment using clofibrate and persantin persantinat on increased serum lipid levels].
    Die Medizinische Welt, 1973, Mar-23, Volume: 24, Issue:12

    Topics: Adult; Cholesterol; Clofibrate; Dipyridamole; Drug Synergism; Humans; Hyperlipidemias; Male; Middle

1973
[Arteriosclerosis].
    Naika. Internal medicine, 1971, Volume: 27, Issue:6

    Topics: Adult; Aged; Arteriosclerosis; Cholestyramine Resin; Diet Therapy; Dipyridamole; Humans; Hyperlipide

1971
[Studies on platelet adhesiveness. II. On various diseases].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1970, Volume: 33, Issue:5

    Topics: Adenosine; Arteriosclerosis; Dextrans; Diabetes Mellitus; Dipyridamole; Female; Fibrinolytic Agents;

1970