dipyridamole has been researched along with Hypercapnia in 3 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility that endogenously released adenosine, a potent vasodilator, is involved in the increase in cerebral blood flow (CBF) response to hypercapnia has been investigated in an anesthetized, paralyzed rat model." | 7.67 | An involvement of adenosine in cerebral blood flow regulation during hypercapnia. ( DeLong, RE; Phillis, JW, 1987) |
| "The purine nucleoside, adenosine, has been implicated as a neuromodulator in central respiratory depression during prolonged exposure to hypoxia." | 5.08 | The effect of dipyridamole and theophylline on hypercapnic ventilatory responses: the role of adenosine. ( Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST, 1997) |
| "In each of 13 healthy subjects, CBF was measured using (15)O-labeled water and PET at rest and during hypercapnia, hypocapnia, and dipyridamole stress; corresponding CBF values were then compared." | 3.70 | Effect of intravenous dipyridamole on cerebral blood flow in humans. A PET study. ( Iida, H; Ito, H; Kinoshita, T; Tamura, Y; Yokoyama, I, 1999) |
| "The possibility that endogenously released adenosine, a potent vasodilator, is involved in the increase in cerebral blood flow (CBF) response to hypercapnia has been investigated in an anesthetized, paralyzed rat model." | 3.67 | An involvement of adenosine in cerebral blood flow regulation during hypercapnia. ( DeLong, RE; Phillis, JW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Griffiths, TL | 1 |
| Christie, JM | 1 |
| Parsons, ST | 1 |
| Holgate, ST | 1 |
| Ito, H | 1 |
| Kinoshita, T | 1 |
| Tamura, Y | 1 |
| Yokoyama, I | 1 |
| Iida, H | 1 |
| Phillis, JW | 1 |
| DeLong, RE | 1 |
1 trial available for dipyridamole and Hypercapnia
| Article | Year |
|---|---|
The effect of dipyridamole and theophylline on hypercapnic ventilatory responses: the role of adenosine.
Topics: Adenosine; Administration, Oral; Adult; Analysis of Variance; Bronchodilator Agents; Carbon Dioxide; | 1997 |
2 other studies available for dipyridamole and Hypercapnia
| Article | Year |
|---|---|
Effect of intravenous dipyridamole on cerebral blood flow in humans. A PET study.
Topics: Aged; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Brain; Cerebrovascular Circulation; D | 1999 |
An involvement of adenosine in cerebral blood flow regulation during hypercapnia.
Topics: Adenosine; Animals; Blood Pressure; Caffeine; Cerebrovascular Circulation; Coformycin; Dipyridamole; | 1987 |