Page last updated: 2024-10-26

dipyridamole and Hernias, Diaphragmatic, Congenital

dipyridamole has been researched along with Hernias, Diaphragmatic, Congenital in 3 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Hernias, Diaphragmatic, Congenital: Protrusion of abdominal structures into the THORAX as a result of embryologic defects in the DIAPHRAGM often present in the neonatal period. It can be isolated, syndromic, non-syndromic or be a part of chromosome abnormality. Associated pulmonary hypoplasia and PULMONARY HYPERTENSION can further complicate stabilization and surgical intervention.

Research Excerpts

ExcerptRelevanceReference
"Congenital diaphragmatic hernia (CDH) remains a frustrating cause of respiratory failure associated with persistent pulmonary hypertension of the newborn (PPHN)."1.30Dypiridamole, a cGMP phosphodiesterase inhibitor, transiently improves the response to inhaled nitric oxide in two newborns with congenital diaphragmatic hernia. ( Farnoux, C; Hartman, JF; Mercier, JC; Saizou, C; Thébaud, B, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thébaud, B2
Saizou, C1
Farnoux, C1
Hartman, JF1
Mercier, JC2
de Lagausie, P1
Forgues, D1
Aigrain, Y1
Dinh-Xuan, AT1
Buysse, C1
Fonteyne, C1
Dessy, H1
De Laet, MH1
Biarent, D1

Other Studies

3 other studies available for dipyridamole and Hernias, Diaphragmatic, Congenital

ArticleYear
Dypiridamole, a cGMP phosphodiesterase inhibitor, transiently improves the response to inhaled nitric oxide in two newborns with congenital diaphragmatic hernia.
    Intensive care medicine, 1999, Volume: 25, Issue:3

    Topics: Administration, Inhalation; Dipyridamole; Fatal Outcome; Hernia, Diaphragmatic; Hernias, Diaphragmat

1999
ET(A)-receptor blockade and ET(B)-receptor stimulation in experimental congenital diaphragmatic hernia.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:5

    Topics: Acetylcholine; Animals; Antihypertensive Agents; Cyclic GMP; Dipyridamole; Disease Models, Animal; E

2000
The use of dipyridamole to wean from inhaled nitric oxide in congenital diaphragmatic hernia.
    Journal of pediatric surgery, 2001, Volume: 36, Issue:12

    Topics: Dipyridamole; Extracorporeal Membrane Oxygenation; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Co

2001