dipyridamole has been researched along with Heart Valve Diseases in 25 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "High-dose dipyridamole transesophageal stress echocardiography has recently been proposed as a useful and safe method to assess myocardial ischemia in patients with poor transthoracic acoustic window." | 7.69 | Usefulness of dipyridamole transesophageal echocardiography in the evaluation of myocardial ischemia and coronary artery flow. ( Ceci, V; Galati, A; Goletta, C; Greco, G; Ricci, R; Richichi, G; Serdoz, R, 1996) |
| "We have recently shown that in patients with single vessel disease and no myocardial infarction, a complex plaque morphology makes myocardium more vulnerable to ischaemia during dipyridamole echocardiography testing." | 7.69 | Impact of culprit lesion morphology on prevalence of provoked myocardial ischaemia in patients with old myocardial infarction. A dipyridamole stress echocardiography, exercise electrocardiography and angiographic study. ( Biagini, A; DeNes, M; Distante, A; L'Abbate, A; Lu, C; Marzilli, M; Wang, Y, 1997) |
| "High-dose dipyridamole transesophageal stress echocardiography has recently been proposed as a useful and safe method to assess myocardial ischemia in patients with poor transthoracic acoustic window." | 3.69 | Usefulness of dipyridamole transesophageal echocardiography in the evaluation of myocardial ischemia and coronary artery flow. ( Ceci, V; Galati, A; Goletta, C; Greco, G; Ricci, R; Richichi, G; Serdoz, R, 1996) |
| "Patients with refractory pulmonary hypertension in whom inhaled nitric oxide alone fails to cause a response may respond to combined therapy of inhaled nitric oxide plus dipyridamole." | 3.69 | Effective control of refractory pulmonary hypertension after cardiac operations. ( Fullerton, DA; Grover, FL; Jaggers, J; McIntyre, RC; Piedalue, F, 1997) |
| "We have recently shown that in patients with single vessel disease and no myocardial infarction, a complex plaque morphology makes myocardium more vulnerable to ischaemia during dipyridamole echocardiography testing." | 3.69 | Impact of culprit lesion morphology on prevalence of provoked myocardial ischaemia in patients with old myocardial infarction. A dipyridamole stress echocardiography, exercise electrocardiography and angiographic study. ( Biagini, A; DeNes, M; Distante, A; L'Abbate, A; Lu, C; Marzilli, M; Wang, Y, 1997) |
| " A larger study is necessary to confirm the relationship between the dosage and outcome." | 1.31 | Oral anticoagulation therapy during pregnancy in patients with mechanical mitral valves: a prospective study. ( Allam, H; Hassouna, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 7 (28.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GRIEP, AH | 1 |
| Espinola-Zavaleta, N | 1 |
| Soto, ME | 1 |
| Bauk, L | 1 |
| Miguel Casanova, J | 1 |
| Keirns, C | 1 |
| Avila Vanzzini, N | 1 |
| Reyes, P | 1 |
| Santini, F | 1 |
| Casali, G | 1 |
| Franchi, G | 1 |
| Auriemma, S | 1 |
| Lusini, M | 1 |
| Barozzi, L | 1 |
| Favaro, A | 1 |
| Messina, A | 1 |
| Mazzucco, A | 1 |
| Weinstein, GS | 1 |
| Mavroudis, C | 1 |
| Ebert, PA | 1 |
| Fuster, V | 3 |
| Chesebro, JH | 1 |
| Turpie, AG | 2 |
| Yamak, B | 1 |
| Sener, E | 1 |
| Kiziltepes, U | 1 |
| Gol, K | 1 |
| Tarcan, O | 1 |
| Mavitas, B | 1 |
| Tasdemir, O | 1 |
| Bayazit, K | 1 |
| Galati, A | 1 |
| Greco, G | 1 |
| Goletta, C | 1 |
| Ricci, R | 1 |
| Serdoz, R | 1 |
| Richichi, G | 1 |
| Ceci, V | 1 |
| Fullerton, DA | 1 |
| Jaggers, J | 1 |
| Piedalue, F | 1 |
| Grover, FL | 1 |
| McIntyre, RC | 1 |
| Lu, C | 1 |
| Distante, A | 1 |
| Marzilli, M | 1 |
| DeNes, M | 1 |
| Wang, Y | 1 |
| Biagini, A | 1 |
| L'Abbate, A | 1 |
| Shibata, M | 1 |
| Sakuma, H | 1 |
| Isaka, N | 1 |
| Takeda, K | 1 |
| Higgins, CB | 1 |
| Nakano, T | 1 |
| Hassouna, A | 1 |
| Allam, H | 1 |
| Strauer, BE | 1 |
| Didisheim, P | 2 |
| Hirsh, J | 1 |
| Nuutinen, LS | 1 |
| Pihlajaniemi, R | 1 |
| Saarela, E | 1 |
| Kärkölä, P | 1 |
| Hollmén, A | 1 |
| Kasahara, T | 1 |
| Kettunen, R | 1 |
| Huikuri, HV | 1 |
| Heikkilä, J | 1 |
| Takkunen, JT | 1 |
| Aubry, P | 1 |
| Assayag, P | 1 |
| Faraggi, M | 1 |
| Haddad, A | 1 |
| Akesbi, A | 1 |
| Messian, O | 1 |
| Brochet, E | 1 |
| Bok, B | 1 |
| Valère, PE | 1 |
| Deans, KW | 1 |
| Hartshorn, JC | 1 |
| Nuñez, L | 1 |
| Pinto, AG | 1 |
| Larrea, JL | 1 |
| Gil Aguado, M | 1 |
| Connor, FO | 1 |
| Dale, J | 1 |
| Nitter-Hauge, S | 1 |
| Takayama, T | 1 |
| Goto, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety And Efficacy of Low Dose Oral Anticoagulants And Aspirin Therapy Throughout Pregnancy In Patients With Mechanical Heart Valves Prosthesis[NCT01758640] | Phase 3 | 200 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for dipyridamole and Heart Valve Diseases
| Article | Year |
|---|---|
Antiplatelet therapy.
Topics: Aspirin; Blood Platelets; Cerebrovascular Disorders; Clofibrate; Coronary Disease; Dipyridamole; Hea | 1981 |
[Quantitative determination of coronary reserve in diagnosis of coronary circulatory disorders].
Topics: Adrenergic beta-Antagonists; Cardiomegaly; Cardiomyopathies; Collagen Diseases; Coronary Circulation | 1977 |
Actions and clinical status of platelet-suppressive agents.
Topics: Aspirin; Blood Platelets; Cerebrovascular Disorders; Coronary Disease; Dipyridamole; Heart Valve Dis | 1978 |
Platelet function inhibitors: their clinical use.
Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Coronary Disease | 1978 |
Platelet suppressive therapy.
Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clofibrate; Coro | 1978 |
2 trials available for dipyridamole and Heart Valve Diseases
| Article | Year |
|---|---|
Series on pharmacology in practice. 10. Antithrombotic therapy: role of platelet-inhibitor drugs. III. Management of arterial thromboembolic and atherosclerotic disease (third of three parts).
Topics: Anticoagulants; Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Coro | 1981 |
[Detection of coronary disease before valve surgery. Contribution of myocardial scintigraphy with dipyridamole].
Topics: Adult; Aged; Aged, 80 and over; Coronary Disease; Dipyridamole; Evaluation Studies as Topic; Female; | 1991 |
18 other studies available for dipyridamole and Heart Valve Diseases
| Article | Year |
|---|---|
NOCTURNAL ANGINA PECTORIS.
Topics: Angina Pectoris; Coronary Disease; Dipyridamole; Duodenal Obstruction; Heart Failure; Heart Valve Di | 1964 |
Coronary reserve in Takayasu's arteritis: transesophageal echocardiographic analysis.
Topics: Adolescent; Adult; Albumins; Contrast Media; Coronary Angiography; Coronary Circulation; Coronary St | 2005 |
Hemodynamic effects of inhaled nitric oxide and phosphodiesterase inhibitor (dipyridamole) on secondary pulmonary hypertension following heart valve surgery in adults.
Topics: Administration, Inhalation; Aged; Analysis of Variance; Aortic Valve; Bronchodilator Agents; Cardiac | 2005 |
Preliminary experience with aspirin for anticoagulation in children with prosthetic cardiac valves.
Topics: Adolescent; Anticoagulants; Aortic Valve; Aspirin; Bioprosthesis; Child; Child, Preschool; Dicumarol | 1982 |
Low dose anticoagulation after St. Jude Medical prosthesis implantation in patients under 18 years of age.
Topics: Adolescent; Anticoagulants; Aortic Valve; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; | 1995 |
Usefulness of dipyridamole transesophageal echocardiography in the evaluation of myocardial ischemia and coronary artery flow.
Topics: Angina Pectoris; Coronary Angiography; Coronary Circulation; Dipyridamole; Echocardiography, Doppler | 1996 |
Effective control of refractory pulmonary hypertension after cardiac operations.
Topics: Aged; Blood Pressure; Dipyridamole; Drug Combinations; Heart Valve Diseases; Hemodynamics; Humans; H | 1997 |
Impact of culprit lesion morphology on prevalence of provoked myocardial ischaemia in patients with old myocardial infarction. A dipyridamole stress echocardiography, exercise electrocardiography and angiographic study.
Topics: Adult; Aged; Coronary Angiography; Coronary Circulation; Dipyridamole; Echocardiography; Echocardiog | 1997 |
Assessment of coronary flow reserve with fast cine phase contrast magnetic resonance imaging: comparison with measurement by Doppler guide wire.
Topics: Blood Flow Velocity; Blood Pressure; Coronary Circulation; Dipyridamole; Female; Heart Valve Disease | 1999 |
Oral anticoagulation therapy during pregnancy in patients with mechanical mitral valves: a prospective study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticoagulants; Dipyridamole; Dose-Response Relations | 2001 |
The effect of dipyridamole on the thrombocyte count and bleeding tendency in open-heart surgery.
Topics: Adolescent; Adult; Blood Cell Count; Blood Coagulation; Blood Platelets; Cardiopulmonary Bypass; Dip | 1977 |
[Clinical effect of dipyridamole ingestion after prosthetic heart valve replacement--especially on the blood coagulation system (author's transl)].
Topics: Adolescent; Adult; Blood Coagulation; Blood Viscosity; Dipyridamole; Female; Heart Valve Diseases; H | 1977 |
Preoperative diagnosis of coronary artery disease in patients with valvular heart disease using technetium-99m isonitrile tomographic imaging together with high-dose dipyridamole and handgrip exercise.
Topics: Coronary Angiography; Coronary Disease; Dipyridamole; Exercise Test; Female; Heart Valve Diseases; H | 1992 |
Use of antithrombotic agents in valvular heart disease.
Topics: Aspirin; Dipyridamole; Heart Valve Diseases; Humans; Patient Education as Topic; Warfarin | 1987 |
Oral anticoagulation is not necessary for patients with bioprosthetic mitral valve replacement in atrial fibrillation.
Topics: Anticoagulants; Aortic Valve; Aspirin; Atrial Fibrillation; Bioprosthesis; Dipyridamole; Drug Therap | 1986 |
Do all patients with mechanical heart valve prostheses need anticoagulant therapy?
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Bioprosthesis; Dipyridamole; Drug Therapy, Combination | 1986 |
[Antithrombogenic therapy based on the study of the changes in platelet aggregability and blood coagulability in the early period after prosthetic valve replacement].
Topics: Adult; Anticoagulants; Blood Coagulation; Dipyridamole; Female; Heart Valve Diseases; Heart Valve Pr | 1985 |
[Clinical pathophysiological studies on the effects of various coronary vasodilators on myocardial carbohydrate metabolism. 2. Effects of various coronary vasodilators on myocardial carbohydrate metabolism in various diseases].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Blood Glucose; Carbohydrate Metabolism; Coronary Di | 1972 |