dipyridamole has been researched along with HbS Disease in 4 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vandorpe, DH | 1 |
| Xu, C | 1 |
| Shmukler, BE | 1 |
| Otterbein, LE | 1 |
| Trudel, M | 1 |
| Sachs, F | 1 |
| Gottlieb, PA | 1 |
| Brugnara, C | 1 |
| Alper, SL | 1 |
| Chaplin, H | 2 |
| Alkjaersig, N | 2 |
| Fletcher, AP | 1 |
| Michael, JM | 1 |
| Joist, JH | 1 |
| Joiner, CH | 1 |
| Jiang, M | 1 |
| Claussen, WJ | 1 |
| Roszell, NJ | 1 |
| Yasin, Z | 1 |
| Franco, RS | 1 |
| Fletcher, A | 1 |
| Joist, H | 1 |
1 trial available for dipyridamole and HbS Disease
| Article | Year |
|---|---|
Aspirin-dipyridamole prophylaxis of sickle cell disease pain crises.
Topics: Acute Disease; Anemia, Sickle Cell; Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, C | 1980 |
3 other studies available for dipyridamole and HbS Disease
| Article | Year |
|---|---|
Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Animals; Calcium; Calcium Cha | 2010 |
Dipyridamole inhibits sickling-induced cation fluxes in sickle red blood cells.
Topics: Anemia, Sickle Cell; Calcium; Cations; Cells, Cultured; Dipyridamole; Dose-Response Relationship, Dr | 2001 |
Hemostatic alterations accompanying sickle cell pain crises.
Topics: Acute Disease; Adult; Anemia, Sickle Cell; Aspirin; Blood Cell Count; Blood Platelets; Blood Transfu | 1976 |