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dipyridamole and Glioma

dipyridamole has been researched along with Glioma in 4 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to analyse the uptake of the synthetic nucleoside tiazofurin and glucoso-linker-tiazofurin conjugate (GLTC) into rat C6 glioma cells in vitro."7.71The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells. ( Begley, DJ; Dacevic, MP; Isakovic, AJ; Pejanovic, VM; Rakic, LM; Redzic, ZB; Segal, MB; Tasic, JS; Ugliesic-Kilibarda, DD, 2002)
"In C6 glioma cells, adenine nucleotides, especially AMP, and adenosine inhibited cell proliferation in time- and concentration-dependent manners."3.74Adenosine uptake-dependent C6 cell growth inhibition. ( Nagata, K; Nakahata, N; Ohkubo, S, 2007)
"The aim of this study was to analyse the uptake of the synthetic nucleoside tiazofurin and glucoso-linker-tiazofurin conjugate (GLTC) into rat C6 glioma cells in vitro."3.71The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells. ( Begley, DJ; Dacevic, MP; Isakovic, AJ; Pejanovic, VM; Rakic, LM; Redzic, ZB; Segal, MB; Tasic, JS; Ugliesic-Kilibarda, DD, 2002)
" In the present study, however, changes in intracellular cyclic AMP level in several lines of cultured cells (normal 3T3 and SV40 and polyomavirus-transformed 3T3 cells; 3T6, C6 GLIOMA, MOUSE L, and Novikoff rat hepatoma cells) by treatment with papaverine, prostaglandine E1 or isoproterenol did not correlate with the inhibition of the uridine, hypoxanthine or deoxyglucose transport rates by these chemicals."3.65Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells. ( Plagemann, PG; Sheppard, JR, 1975)
"5."1.32Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis. ( Kaulich, M; Müller, CE; Qurishi, R, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dacevic, MP1
Tasic, JS1
Pejanovic, VM1
Segal, MB1
Ugliesic-Kilibarda, DD1
Isakovic, AJ1
Begley, DJ1
Rakic, LM1
Redzic, ZB1
Kaulich, M1
Qurishi, R1
Müller, CE1
Ohkubo, S1
Nagata, K1
Nakahata, N1
Sheppard, JR1
Plagemann, PG1

Other Studies

4 other studies available for dipyridamole and Glioma

ArticleYear
The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells.
    Journal of drug targeting, 2002, Volume: 10, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Binding, Competitive; Cell Membrane; Chromatography, High

2002
Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis.
    Cellular and molecular neurobiology, 2003, Volume: 23, Issue:3

    Topics: Adenosine; Alkaline Phosphatase; Animals; Chromatography, Micellar Electrokinetic Capillary; Dipyrid

2003
Adenosine uptake-dependent C6 cell growth inhibition.
    European journal of pharmacology, 2007, Dec-22, Volume: 577, Issue:1-3

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosi

2007
Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells.
    Journal of cellular physiology, 1975, Volume: 85, Issue:2 Pt 1

    Topics: Animals; Biological Transport, Active; Bucladesine; Carcinoma, Hepatocellular; Cell Division; Cell L

1975