dipyridamole has been researched along with Glioma in 4 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to analyse the uptake of the synthetic nucleoside tiazofurin and glucoso-linker-tiazofurin conjugate (GLTC) into rat C6 glioma cells in vitro." | 7.71 | The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells. ( Begley, DJ; Dacevic, MP; Isakovic, AJ; Pejanovic, VM; Rakic, LM; Redzic, ZB; Segal, MB; Tasic, JS; Ugliesic-Kilibarda, DD, 2002) |
| "In C6 glioma cells, adenine nucleotides, especially AMP, and adenosine inhibited cell proliferation in time- and concentration-dependent manners." | 3.74 | Adenosine uptake-dependent C6 cell growth inhibition. ( Nagata, K; Nakahata, N; Ohkubo, S, 2007) |
| "The aim of this study was to analyse the uptake of the synthetic nucleoside tiazofurin and glucoso-linker-tiazofurin conjugate (GLTC) into rat C6 glioma cells in vitro." | 3.71 | The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells. ( Begley, DJ; Dacevic, MP; Isakovic, AJ; Pejanovic, VM; Rakic, LM; Redzic, ZB; Segal, MB; Tasic, JS; Ugliesic-Kilibarda, DD, 2002) |
| " In the present study, however, changes in intracellular cyclic AMP level in several lines of cultured cells (normal 3T3 and SV40 and polyomavirus-transformed 3T3 cells; 3T6, C6 GLIOMA, MOUSE L, and Novikoff rat hepatoma cells) by treatment with papaverine, prostaglandine E1 or isoproterenol did not correlate with the inhibition of the uridine, hypoxanthine or deoxyglucose transport rates by these chemicals." | 3.65 | Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells. ( Plagemann, PG; Sheppard, JR, 1975) |
| "5." | 1.32 | Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis. ( Kaulich, M; Müller, CE; Qurishi, R, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dacevic, MP | 1 |
| Tasic, JS | 1 |
| Pejanovic, VM | 1 |
| Segal, MB | 1 |
| Ugliesic-Kilibarda, DD | 1 |
| Isakovic, AJ | 1 |
| Begley, DJ | 1 |
| Rakic, LM | 1 |
| Redzic, ZB | 1 |
| Kaulich, M | 1 |
| Qurishi, R | 1 |
| Müller, CE | 1 |
| Ohkubo, S | 1 |
| Nagata, K | 1 |
| Nakahata, N | 1 |
| Sheppard, JR | 1 |
| Plagemann, PG | 1 |
4 other studies available for dipyridamole and Glioma
| Article | Year |
|---|---|
The linkage of glucose to tiazofurin decreases in vitro uptake into rat glioma C6 cells.
Topics: Animals; Antimetabolites, Antineoplastic; Binding, Competitive; Cell Membrane; Chromatography, High | 2002 |
Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis.
Topics: Adenosine; Alkaline Phosphatase; Animals; Chromatography, Micellar Electrokinetic Capillary; Dipyrid | 2003 |
Adenosine uptake-dependent C6 cell growth inhibition.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosi | 2007 |
Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells.
Topics: Animals; Biological Transport, Active; Bucladesine; Carcinoma, Hepatocellular; Cell Division; Cell L | 1975 |