Page last updated: 2024-10-26

dipyridamole and Gasser Syndrome

dipyridamole has been researched along with Gasser Syndrome in 31 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"From 1976 to 1985, a total of 58 infants and children with the hemolytic-uremic syndrome were randomly assigned to treatment either with heparin and dipyridamole or with supportive management only."9.06Heparin plus dipyridamole in childhood hemolytic-uremic syndrome: a prospective, randomized study. ( Binda ki Muaka, P; Eeckels, R; Mercieca, V; Proesmans, W; Van Damme, B; Van Damme-Lombaerts, R; Vermylen, J; Vlietinck, R, 1988)
"Three children with the hemolytic-uremic syndrome were treated with heparin, aspirin, and dipyridamole."7.65Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole. ( Arenson, EB; August, CS, 1975)
"From 1976 to 1985, a total of 58 infants and children with the hemolytic-uremic syndrome were randomly assigned to treatment either with heparin and dipyridamole or with supportive management only."5.06Heparin plus dipyridamole in childhood hemolytic-uremic syndrome: a prospective, randomized study. ( Binda ki Muaka, P; Eeckels, R; Mercieca, V; Proesmans, W; Van Damme, B; Van Damme-Lombaerts, R; Vermylen, J; Vlietinck, R, 1988)
"Three children with hemolytic-uremic syndrome (HUS) were successfully treated with plasmapheresis (HUS) were successfully treated with plasmapheresis (PP) combined with early hemodialysis and administration of Aspirin and dipyridamole."3.66Plasmapheresis as a therapeutic measure in hemolytic-uremic syndrome in children. ( Bulla, M; Bussmann, K; Gillor, A; Gladtke, E; Roth, B; Schrör, K; Tekook, A, 1983)
"In four patients with clinical and laboratory manifestations of the hemolytic-uremic syndrome, the administration of aspirin and dipyridamole was associated with a dramatic and rapid increase in the platelet count."3.66The treatment of the hemolytic-uremic syndrome with inhibitors of platelet function. ( Carone, FA; Green, D; Rossi, EC; Thorsen, CA, 1979)
"Three children with the hemolytic-uremic syndrome were treated with heparin, aspirin, and dipyridamole."3.65Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole. ( Arenson, EB; August, CS, 1975)
"Prednisone alone was judged to be effective in 30 patients with mild TTP-HUS (two relapses and two deaths)."2.67Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Clinical experience in 108 patients. ( Bell, WR; Braine, HG; Kickler, TS; Ness, PM, 1991)
" Optimum drug or combination of drugs and dosage are still controversial."1.26[Inhibition of platelet function in pediatric medicine (author's transl)]. ( Schmidt, B, 1982)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199028 (90.32)18.7374
1990's3 (9.68)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gillor, A1
Bulla, M1
Roth, B1
Bussmann, K1
Schrör, K1
Tekook, A1
Gladtke, E1
Proesmans, W3
Thysell, H1
Oxelius, VA1
Norlin, M1
Willoughby, ML1
Fong, JS1
de Chadarevian, JP1
Kaplan, BS1
Schmidt, B1
Binda ki Muaka, P2
Eeckels, R2
Ponticelli, C2
Rivolta, E1
Imbasciati, E2
Rossi, E2
Mannucci, PM1
Gomperts, ED1
Lieberman, E1
O'Regan, S1
Chesney, RW1
Mongeau, JG1
Robitaille, P1
Oshima, T1
Weissbach, G1
Zannino, L1
Salvadori, G1
Thorsen, CA1
Rossi, EC1
Green, D1
Carone, FA1
Mori, H1
Maestri, O1
Brancaccio, D1
Berberich, FR1
Arenson, EB1
August, CS1
Naruse, T1
Bell, WR1
Braine, HG1
Ness, PM1
Kickler, TS1
Valnícek, S1
Dolezel, J1
Hrubanová, J1
Habancová, M1
Stejskal, J1
Van Damme-Lombaerts, R1
Van Damme, B1
Mercieca, V1
Vlietinck, R1
Vermylen, J1
Lazebnik, N1
Jaffa, AJ1
Peyeser, MR1
Wu, KK1
Ekert, E1
George, CR1
Slichter, SJ2
Quadracci, LJ1
Striker, GE1
Harker, LA2
Utting, JA1
Shreeve, DR1
Dacie, JV1
Powell, HR1
Ekert, H1
Wehinger, H1
Sutor, HA1
Schindera, F1
Künzer, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Retrospective, Observational Study on the Response to Caplacizumab Treatment in aTTP Patients: the Italian Experience (ROSCAPLI)[NCT05262881]50 participants (Anticipated)Observational2022-03-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for dipyridamole and Gasser Syndrome

ArticleYear
[Congenital and acquired thrombocyte function disorders].
    Kinderarztliche Praxis, 1980, Volume: 48, Issue:7

    Topics: Aspirin; Blood Platelet Disorders; Dipyridamole; Fibrin Fibrinogen Degradation Products; Heart Defec

1980
Hemolytic-uremic syndrome. Current concepts and management.
    Pediatric clinics of North America, 1982, Volume: 29, Issue:4

    Topics: Anemia, Hemolytic; Blood Transfusion; Child; Child, Preschool; Dipyridamole; Epoprostenol; Follow-Up

1982
[Thrombosis prevention and treatment in pediatrics].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Jan-01, Volume: 34, Issue:1

    Topics: Adolescent; Arterial Occlusive Diseases; Aspirin; Bioprosthesis; Child; Child, Preschool; Coumarins;

1979
[Platelet aggregation inhibitors. Their possible use in pediatric pathology].
    Minerva pediatrica, 1979, Jan-31, Volume: 31, Issue:2

    Topics: Age Factors; Anti-Inflammatory Agents; Aspirin; Child; Clofibrate; Dextrans; Diabetes Mellitus, Type

1979
Hemolytic-uremic syndrome in pregnancy. Review of the literature and report of a case.
    Obstetrical & gynecological survey, 1985, Volume: 40, Issue:10

    Topics: Adult; Antihypertensive Agents; Dipyridamole; Female; Hemolytic-Uremic Syndrome; Humans; Pregnancy;

1985

Trials

2 trials available for dipyridamole and Gasser Syndrome

ArticleYear
Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Clinical experience in 108 patients.
    The New England journal of medicine, 1991, Aug-08, Volume: 325, Issue:6

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Transfusion; Dipyridamole; Female; Hemolytic-Uremic Syndrome

1991
Heparin plus dipyridamole in childhood hemolytic-uremic syndrome: a prospective, randomized study.
    The Journal of pediatrics, 1988, Volume: 113, Issue:5

    Topics: Adolescent; Anuria; Child; Child, Preschool; Dipyridamole; Drug Therapy, Combination; Female; Hemoly

1988

Other Studies

24 other studies available for dipyridamole and Gasser Syndrome

ArticleYear
Plasmapheresis as a therapeutic measure in hemolytic-uremic syndrome in children.
    Klinische Wochenschrift, 1983, Apr-01, Volume: 61, Issue:7

    Topics: Aspirin; Child, Preschool; Dipyridamole; Epoprostenol; Female; Hemolytic-Uremic Syndrome; Humans; In

1983
[Hemolytic-uremic syndrome].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1983, Volume: 131, Issue:6

    Topics: Biopsy; Child; Dipyridamole; Hemolytic-Uremic Syndrome; Heparin; Humans; Kidney

1983
Successful treatment of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura with fresh frozen plasma and plasma exchange.
    Acta medica Scandinavica, 1982, Volume: 212, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aspirin; Child; Child, Preschool; Dipyridamole; Female;

1982
[Inhibition of platelet function in pediatric medicine (author's transl)].
    Klinische Padiatrie, 1982, Volume: 194, Issue:2

    Topics: Age Factors; Aspirin; Child; Dipyridamole; Glomerulonephritis; Graft Rejection; Heart Defects, Conge

1982
The haemolytic uraemic syndrome in childhood: a study of the long-term prognosis.
    European journal of pediatrics, 1981, Volume: 136, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Dipyridamole; Female; Hemolytic-Uremic Syndrome; Heparin; Human

1981
Hemolytic uremic syndrome in adults.
    Archives of internal medicine, 1980, Volume: 140, Issue:3

    Topics: Adult; Dipyridamole; Female; Follow-Up Studies; Hemolytic-Uremic Syndrome; Heparin; Humans; Male; Pr

1980
Hemolytic-uremic syndrome.
    The Journal of pediatrics, 1980, Volume: 97, Issue:3

    Topics: Aspirin; Child; Dipyridamole; Hemolytic-Uremic Syndrome; Humans; Peritoneal Dialysis; Plasma Exchang

1980
Aspirin and dipyridamole therapy in the hemolytic-uremic syndrome.
    The Journal of pediatrics, 1980, Volume: 97, Issue:3

    Topics: Aspirin; Child; Child, Preschool; Dipyridamole; Evaluation Studies as Topic; Female; Hemolytic-Uremi

1980
[Predictive factors for development of hemolytic uremic syndrome (HUS) and early intensive treatments for prevention of HUS enterohemorrhagic Escherichia coli infection].
    The Japanese journal of antibiotics, 1997, Volume: 50, Issue:11

    Topics: Abdominal Pain; Adolescent; Age Factors; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroi

1997
The treatment of the hemolytic-uremic syndrome with inhibitors of platelet function.
    The American journal of medicine, 1979, Volume: 66, Issue:4

    Topics: Adult; Aspirin; Blood Platelets; Cell Count; Dipyridamole; Female; Hemolytic-Uremic Syndrome; Humans

1979
[An adult case of hemolytic-uremic syndrome treated with inhibitors of platelet functions (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1979, Volume: 20, Issue:11

    Topics: Aspirin; Blood Platelets; Dipyridamole; Hemolytic-Uremic Syndrome; Humans; Male; Middle Aged; Renal

1979
Late recovery of renal function in a woman with the hemolytic uremic syndrome.
    Clinical nephrology, 1977, Volume: 8, Issue:2

    Topics: Adult; Contraceptives, Oral, Combined; Dipyridamole; Ethinyl Estradiol; Female; Hemolytic-Uremic Syn

1977
Letter: Treatment of hemolytic-uremic syndrome.
    The Journal of pediatrics, 1975, Volume: 86, Issue:1

    Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Hemolytic-Uremic Syndrome; Heparin; Humans; Strept

1975
Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole.
    The Journal of pediatrics, 1975, Volume: 86, Issue:6

    Topics: Acute Disease; Anemia, Hemolytic; Aspirin; Blood Platelet Disorders; Blood Platelets; Blood Transfus

1975
[Kidney diseases associated with hemolytic uremic syndrome,thrombotic thrombocytopenic purpura and disseminated intravascular coagulation].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jan-10, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Aspirin; Dipyridamole; Disseminated Intravascular Coagulation; Female; Hemolytic-

1992
Importance of blood clotting tests in the diagnosis of haemolytic-uremic syndrome and experience with its treatment.
    Folia haematologica (Leipzig, Germany : 1928), 1988, Volume: 115, Issue:3

    Topics: Blood Coagulation Tests; Child, Preschool; Dipyridamole; Fibrin Fibrinogen Degradation Products; Hem

1988
Microvascular thrombosis: pathophysiology and new strategies.
    Hospital practice (Office ed.), 1985, May-15, Volume: 20, Issue:5

    Topics: Arachidonic Acid; Arachidonic Acids; Dipyridamole; Disseminated Intravascular Coagulation; Epoproste

1985
Letter: Thrombolytic therapy in haemolytic-uraemic syndrome.
    British medical journal, 1974, Nov-30, Volume: 4, Issue:5943

    Topics: Child; Dipyridamole; Hemolytic-Uremic Syndrome; Heparin; Humans; Shwartzman Phenomenon; Streptokinas

1974
A kinetic evaluation of hemostasis in renal disease.
    The New England journal of medicine, 1974, Nov-21, Volume: 291, Issue:21

    Topics: Aspirin; Blood Coagulation; Complement System Proteins; Diabetic Nephropathies; Dipyridamole; Fibrin

1974
Platelet and fibrinogen consumption in man.
    The New England journal of medicine, 1972, Nov-16, Volume: 287, Issue:20

    Topics: Blood Cell Count; Blood Platelets; Catheterization; Cell Survival; Dipyridamole; Disseminated Intrav

1972
Haemolytic-uraemic syndrome in an adult with pericarditis and pleurisy.
    British medical journal, 1973, Jun-09, Volume: 2, Issue:5866

    Topics: Adult; Alopecia; Anemia, Hemolytic; Aspirin; Dipyridamole; Female; Hemolytic-Uremic Syndrome; Hepari

1973
[Hemolytic-uremic syndrome and microangiopathic hemolytic anemia].
    Recenti progressi in medicina, 1973, Volume: 54, Issue:1

    Topics: Adrenal Cortex Hormones; Anemia, Hemolytic; Aspirin; Dextrans; Dipyridamole; Drug Hypersensitivity;

1973
Streptokinase and anti-thrombotic therapy in the hemolytic-uremic syndrome.
    The Journal of pediatrics, 1974, Volume: 84, Issue:3

    Topics: Aspirin; Biopsy; Child; Child, Preschool; Dipyridamole; Hemolytic-Uremic Syndrome; Hemorrhage; Hepar

1974
[Therapy of the hemolytic-uremic syndrome].
    Deutsche medizinische Wochenschrift (1946), 1974, Apr-19, Volume: 99, Issue:16

    Topics: Aspirin; Dipyridamole; Hemolytic-Uremic Syndrome; Heparin; Humans; Methods; Peritoneal Dialysis; Pla

1974