dipyridamole has been researched along with Fibrosarcoma in 2 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been observed that adenosine suppresses the growth of G:5:113 murine fibrosarcoma cells in vitro with EC50 of 178 mM." | 7.72 | Effects of adenosine on the growth of murine G:5:113 fibrosarcoma cells in vitro. ( Chramostová, K; Hofer, M; Hoferová, Z; Pospísil, M; Znojil, V, 2003) |
| "We examined the ability of dipyridamole (DPM) to act synergistically with vinblastine (VBL) in HT1080 fibrosarcoma cells and a drug-resistant variant, HT1080/DR4, which lacks mdr1 expression, in order to determine whether DPM requires P-glycoprotein to modulate drug sensitivity." | 7.68 | Modulation of vinblastine sensitivity by dipyridamole in multidrug resistant fibrosarcoma cells lacking mdr1 expression. ( Howell, SB; Shalinsky, DR; Slovak, ML, 1991) |
| "It has been observed that adenosine suppresses the growth of G:5:113 murine fibrosarcoma cells in vitro with EC50 of 178 mM." | 3.72 | Effects of adenosine on the growth of murine G:5:113 fibrosarcoma cells in vitro. ( Chramostová, K; Hofer, M; Hoferová, Z; Pospísil, M; Znojil, V, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hofer, M | 1 |
| Hoferová, Z | 1 |
| Pospísil, M | 1 |
| Znojil, V | 1 |
| Chramostová, K | 1 |
| Shalinsky, DR | 1 |
| Slovak, ML | 1 |
| Howell, SB | 1 |
2 other studies available for dipyridamole and Fibrosarcoma
| Article | Year |
|---|---|
Effects of adenosine on the growth of murine G:5:113 fibrosarcoma cells in vitro.
Topics: Adenosine; Animals; Cell Cycle; Cell Division; Cell Line, Tumor; Dipyridamole; Fibrosarcoma; Mice | 2003 |
Modulation of vinblastine sensitivity by dipyridamole in multidrug resistant fibrosarcoma cells lacking mdr1 expression.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Dipyridamole; Drug Resistance; Drug Synergi | 1991 |