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dipyridamole and Fetal Growth Restriction

dipyridamole has been researched along with Fetal Growth Restriction in 15 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of low-dose aspirin in preventing fetal growth retardation was tested in a randomised, placebo-controlled, double-blind trial."9.07Prevention of fetal growth retardation with low-dose aspirin: findings of the EPREDA trial. ( Bazin, B; Beaufils, M; Breart, G; Capitant, C; Paris, J; Uzan, S, 1991)
"A multicentric randomized double-blind trial was realized in order to determine whether a treatment with a low-dose aspirin (150 mg/day) with or without dipyridamole (225 mg/day) was able to prevent the perinatal consequences of pre-eclampsia."9.07Prevention of perinatal consequences of pre-eclampsia with low-dose aspirin: results of the epreda trial. The Epreda Trial Study Group. ( Sureau, C, 1991)
" Low-dose aspirin and dipyridamole direct prostacyclin/thromboxane A2 balance in pregnancy to the dominance of prostacyclin and may thus prevent idiopathic uteroplacental insufficiency and fetal growth retardation in high-risk patients."9.06Prevention of recurrent idiopathic fetal growth retardation by low-dose aspirin and dipyridamole. ( Rotmans, N; Wallenburg, HC, 1987)
"Quantitative sphygmometry was used to check the cardiovascular action of an intravenous injection of 30 mg of dipyridamole in ten women, between the 31st and 38th weeks of pregnancy."7.66[Cardiovascular action of dipyridamole in advanced pregnancy (author's transl)]. ( Lauckner, W; Retzke, U; Schwarz, R, 1981)
"The efficacy of low-dose aspirin in preventing fetal growth retardation was tested in a randomised, placebo-controlled, double-blind trial."5.07Prevention of fetal growth retardation with low-dose aspirin: findings of the EPREDA trial. ( Bazin, B; Beaufils, M; Breart, G; Capitant, C; Paris, J; Uzan, S, 1991)
"A multicentric randomized double-blind trial was realized in order to determine whether a treatment with a low-dose aspirin (150 mg/day) with or without dipyridamole (225 mg/day) was able to prevent the perinatal consequences of pre-eclampsia."5.07Prevention of perinatal consequences of pre-eclampsia with low-dose aspirin: results of the epreda trial. The Epreda Trial Study Group. ( Sureau, C, 1991)
" Low-dose aspirin and dipyridamole direct prostacyclin/thromboxane A2 balance in pregnancy to the dominance of prostacyclin and may thus prevent idiopathic uteroplacental insufficiency and fetal growth retardation in high-risk patients."5.06Prevention of recurrent idiopathic fetal growth retardation by low-dose aspirin and dipyridamole. ( Rotmans, N; Wallenburg, HC, 1987)
"Quantitative sphygmometry was used to check the cardiovascular action of an intravenous injection of 30 mg of dipyridamole in ten women, between the 31st and 38th weeks of pregnancy."3.66[Cardiovascular action of dipyridamole in advanced pregnancy (author's transl)]. ( Lauckner, W; Retzke, U; Schwarz, R, 1981)
"The pregnancy was normal in 54% of patients in group A and 23% in group B (p less than 0."2.65[Controlled trial of preventive treatment of preeclampsia. Preliminary results]. ( Beaufils, M; Colau, JC; Donsimoni, R; Uzan, S, 1984)
"Aspirin (ASS) was the most frequently used drug in 47 of 93 recorded cases (51%)."2.39Essential thrombocythemia and pregnancy. ( Griesshammer, M; Heimpel, H; Pearson, TC, 1996)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's6 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beaufils, M5
Uzan, S5
Donsimoni, R2
Colau, JC2
van Wersch, JW1
Zandvoort, JA1
van Dieijen-Visser, MP1
Lauckner, W1
Schwarz, R1
Retzke, U1
Fursova, ZK1
Balika, IuD1
Mamedalieva, NM1
Razumovskaia, IN1
Griesshammer, M1
Heimpel, H1
Pearson, TC1
Pollack, RN1
Yaffe, H1
Divon, MY1
Bonnar, J1
Redman, CW1
Sheppard, BL1
Bréart, G2
Uzan, M1
Paris, J2
Bazin, B2
Capitant, C1
Sureau, C1
Danays, T1
Wallenburg, HC2
Rotmans, N2
Falconer, J1
Pineo, G1
Blahey, W1
Bowen, T1
Docksteader, B1
Jadusingh, I1

Reviews

2 reviews available for dipyridamole and Fetal Growth Restriction

ArticleYear
Essential thrombocythemia and pregnancy.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Aspirin; Busulfan; Combined Modality Therapy; Di

1996
Therapy for intrauterine growth restriction: current options and future directions.
    Clinical obstetrics and gynecology, 1997, Volume: 40, Issue:4

    Topics: Adrenergic beta-Agonists; Aspirin; Atrial Natriuretic Factor; Bed Rest; Cyclooxygenase Inhibitors; D

1997

Trials

7 trials available for dipyridamole and Fetal Growth Restriction

ArticleYear
[Controlled trial of preventive treatment of preeclampsia. Preliminary results].
    Archives des maladies du coeur et des vaisseaux, 1984, Volume: 77, Issue:11

    Topics: Adult; Aspirin; Blood Volume; Clinical Trials as Topic; Dipyridamole; Female; Fetal Growth Retardati

1984
[Prevention of intrauterine growth retardation and pre-eclampsia by small doses of aspirin. Results of the french multicenter trial EPREDA and comparison with data in the literature; value of uterine Doppler].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1992, Volume: 21, Issue:3

    Topics: Aspirin; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Female; Fetal Growth Retardat

1992
Prevention of fetal growth retardation with low-dose aspirin: findings of the EPREDA trial.
    Lancet (London, England), 1991, Jun-15, Volume: 337, Issue:8755

    Topics: Adult; Aspirin; Birth Weight; Dipyridamole; Double-Blind Method; Drug Administration Schedule; Drug

1991
Prevention of perinatal consequences of pre-eclampsia with low-dose aspirin: results of the epreda trial. The Epreda Trial Study Group.
    European journal of obstetrics, gynecology, and reproductive biology, 1991, Aug-20, Volume: 41, Issue:1

    Topics: Abruptio Placentae; Aspirin; Birth Weight; Dipyridamole; Double-Blind Method; Drug Combinations; Fem

1991
Idiopathic recurrent fetal growth retardation and aspirin-dipyridamole therapy.
    American journal of obstetrics and gynecology, 1989, Volume: 160, Issue:3

    Topics: Aspirin; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Female; Fetal Growth Ret

1989
Prospective controlled study of early antiplatelet therapy in prevention of preeclampsia.
    Advances in nephrology from the Necker Hospital, 1986, Volume: 15

    Topics: Adult; Aspirin; Clinical Trials as Topic; Dipyridamole; Female; Fetal Growth Retardation; Humans; Pa

1986
Prevention of recurrent idiopathic fetal growth retardation by low-dose aspirin and dipyridamole.
    American journal of obstetrics and gynecology, 1987, Volume: 157, Issue:5

    Topics: Adult; Aspirin; Birth Weight; Clinical Trials as Topic; Dipyridamole; Epoprostenol; Female; Fetal Gr

1987

Other Studies

6 other studies available for dipyridamole and Fetal Growth Restriction

ArticleYear
Heparin-dipyridamole (Persantin) treatment in pregnancy: effect on blood coagulation parameters.
    Haemostasis, 1983, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Clot Retraction; Dipyridamole; Female; Fetal Growth Retardation; Fibrin Fibrinoge

1983
[Cardiovascular action of dipyridamole in advanced pregnancy (author's transl)].
    Zentralblatt fur Gynakologie, 1981, Volume: 103, Issue:4

    Topics: Adult; Dipyridamole; Female; Fetal Growth Retardation; Hemodynamics; Humans; Placental Insufficiency

1981
[Characteristics of lymphocytic enzyme status of the newborn after metabolic therapy of pregnant women].
    Akusherstvo i ginekologiia, 1995, Issue:4

    Topics: Abortion, Habitual; Benzenesulfonates; Dipyridamole; Estradiol Congeners; Female; Fetal Growth Retar

1995
Treatment of fetal growth retardation in utero with heparin and dipyridamole.
    European journal of obstetrics, gynecology, and reproductive biology, 1975, Volume: 5, Issue:1-2

    Topics: Dipyridamole; Female; Fetal Growth Retardation; Heparin; Humans; Hypertension; Placenta; Placental F

1975
Prophylactic low-dose aspirin and dipyridamole in pregnancy.
    Lancet (London, England), 1988, Apr-23, Volume: 1, Issue:8591

    Topics: Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Fetal Death; Fetal Growth Retardation; Hum

1988
Essential thrombocythemia associated with recurrent abortions and fetal growth retardation.
    American journal of hematology, 1987, Volume: 25, Issue:3

    Topics: Abortion, Habitual; Adult; Aspirin; Dipyridamole; Female; Fetal Growth Retardation; Humans; Platelet

1987