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dipyridamole and Elevated Cholesterol

dipyridamole has been researched along with Elevated Cholesterol in 17 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"Dipyridamole anti-platelet therapy has previously been suggested to ameliorate chronic tissue ischemia in healthy animals."7.77Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress. ( Bir, SC; Branch, BG; Greber, E; Kevil, CG; Pardue, S; Patel, RP; Pattillo, CB; Shen, X, 2011)
"Dipyridamole anti-platelet therapy has previously been suggested to ameliorate chronic tissue ischemia in healthy animals."3.77Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress. ( Bir, SC; Branch, BG; Greber, E; Kevil, CG; Pardue, S; Patel, RP; Pattillo, CB; Shen, X, 2011)
"An all the patients with left ventricular hypertrophy (LVH) had decreased CFVR whose values with the myocardial mass index above 130 g/m2 were significantly less than those in the absence of LVH."1.32[Coronary flow vasodilator reserve in patients with type 2 diabetes mellitus-associated arterial hypertension]. ( Efimova, EV; Karpov, RS; Koshel'skaia, OA; Ocheredko, NA; Panafidin, AV; Soldatenko, MV, 2004)
"Hypertriglyceridemia is an independent factor for this abnormality."1.30Altered myocardial vasodilatation in patients with hypertriglyceridemia in anatomically normal coronary arteries. ( Aoyagi, T; Kobayakawa, N; Momomura, S; Ohtake, T; Omata, M; Sasaki, Y; Sugiura, S; Yokoyama, I; Yonekura, K, 1998)
"When dipyridamole was administered in chickens fed the same diet without cholesterol no significant changes were observed."1.28Antihypercholesterolemic effect of dipyridamole in chickens. ( Arenas, C; Sánchez-Medina, F; Sánchez-Pozo, A, 1992)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's5 (29.41)18.2507
2000's6 (35.29)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gimelli, A1
Marzullo, P1
L'Abbate, A1
Rovai, D1
Pattillo, CB1
Bir, SC1
Branch, BG1
Greber, E1
Shen, X1
Pardue, S1
Patel, RP1
Kevil, CG1
García-Fuentes, E2
Gil-Villarino, A2
Zafra, MF2
García-Peregrín, E2
Nemes, A1
Neu, K1
Forster, T1
Gruber, N1
Csanády, M1
Karpov, RS1
Koshel'skaia, OA1
Soldatenko, MV1
Efimova, EV1
Ocheredko, NA1
Panafidin, AV1
Zhong, ZM1
Yu, L1
Weng, ZY1
Hao, ZH1
Zhang, L1
Zhang, YX1
Dong, WQ1
Stamler, J1
Yokoyama, I3
Ohtake, T3
Momomura, S3
Nishikawa, J1
Sasaki, Y3
Omata, M3
Yonekura, K2
Kobayakawa, N2
Aoyagi, T2
Sugiura, S2
Baller, D1
Gleichmann, U1
Notohamiprodjo, G1
Weise, R1
Holzinger, J1
Montanus, H1
Betker, S1
Lehmann, J1
Yang, W1
Yamada, N1
Ohtomo, K1
Yazaki, Y1
Faergeman, O1
Gormsen, J1
Meinertz, H1
Sánchez-Pozo, A1
Arenas, C1
Sánchez-Medina, F1
Aviram, M1
Winterstein, G1
Brook, JG1
Verbeuren, TJ1
Coene, MC1
Jordaens, FH1
Van Hove, CE1
Zonnekeyn, LL1
Herman, AG1
Velasco Martin, A1
Perezagua Clamagirand, C1

Trials

2 trials available for dipyridamole and Elevated Cholesterol

ArticleYear
[Therapeutic effect of Ginkgo biloba leaf extract on hypercholestrolemia in children with nephrotic syndrome].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Dipyridamole; Drug Therapy, Combination; Female; Ginkgo biloba;

2007
Pharmacological trials: primary and secondary prevention of coronary heart disease.
    Preventive medicine, 1983, Volume: 12, Issue:1

    Topics: Aspirin; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Colestipol; Coronary Disease; D

1983

Other Studies

15 other studies available for dipyridamole and Elevated Cholesterol

ArticleYear
'False-positive' myocardial perfusion imaging: correlation with cardiovascular risk factors and effect on event-free survival.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2008, Volume: 9, Issue:7

    Topics: Aged; Angina Pectoris; Coronary Circulation; Diabetes Mellitus; Dipyridamole; Electrocardiography; E

2008
Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress.
    Free radical biology & medicine, 2011, Jan-15, Volume: 50, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Dipyridamole; Disease Models, Animal; Hindlimb; Hyperchole

2011
Changes in plasma lipid composition induced by coconut oil. Effects of dipyridamole.
    Journal of physiology and biochemistry, 2002, Volume: 58, Issue:1

    Topics: Animals; Chickens; Coconut Oil; Dietary Fats; Dipyridamole; Hypercholesterolemia; Lipids; Male; Plan

2002
Relationship between hypercholesterolemia, lipid-lowering therapy and coronary flow velocity reserve evaluated by stress transesophageal echocardiography in patients with a negative coronary angiogram.
    Echocardiography (Mount Kisco, N.Y.), 2004, Volume: 21, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Blood Flow Velocity; Cholesterol; Coronary Angiography; Coron

2004
[Coronary flow vasodilator reserve in patients with type 2 diabetes mellitus-associated arterial hypertension].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:6

    Topics: Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Dipyridamole; Echocardiogr

2004
Reduced coronary flow reserve in hypercholesterolemic patients without overt coronary stenosis.
    Circulation, 1996, Dec-15, Volume: 94, Issue:12

    Topics: Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cineangiography; Coronary Angiograp

1996
Altered myocardial vasodilatation in patients with hypertriglyceridemia in anatomically normal coronary arteries.
    Arteriosclerosis, thrombosis, and vascular biology, 1998, Volume: 18, Issue:2

    Topics: Aged; Coronary Circulation; Coronary Vessels; Dipyridamole; Electrocardiography; Female; Hemodynamic

1998
[Improved coronary vasodilator capacity by drug lipid lowering therapy in patients in the early stage of coronary atherosclerosis with reduced coronary reserves and moderate LDL hypercholesteremia].
    Zeitschrift fur Kardiologie, 1998, Volume: 87 Suppl 2

    Topics: Adult; Aged; Cholesterol, LDL; Combined Modality Therapy; Coronary Angiography; Coronary Artery Dise

1998
Improvement of impaired myocardial vasodilatation due to diffuse coronary atherosclerosis in hypercholesterolemics after lipid-lowering therapy.
    Circulation, 1999, Jul-13, Volume: 100, Issue:2

    Topics: Aged; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Diabetes Mellitus; Dipyridamo

1999
Dipyridamole prevents the coconut oil-induced hypercholesterolemia. A study on lipid plasma and lipoprotein composition.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:3

    Topics: Animals; Chickens; Coconut Oil; Dietary Fats; Dipyridamole; Food Deprivation; Hypercholesterolemia;

2002
Anti-platelet drugs and portacaval anastomosis for homozygous hypercholesterolaemia.
    Lancet (London, England), 1976, Dec-25, Volume: 2, Issue:8000

    Topics: Adolescent; Adult; Aspirin; Child; Dipyridamole; Female; Homozygote; Humans; Hypercholesterolemia; M

1976
Antihypercholesterolemic effect of dipyridamole in chickens.
    European journal of pharmacology, 1992, May-01, Volume: 228, Issue:1

    Topics: Animals; Chickens; Cholesterol; Cholesterol, Dietary; Dipyridamole; Hypercholesterolemia; Lipoprotei

1992
Differential effect of platelet inhibitors in normal and in hypercholesterolaemic subjects.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:6

    Topics: Adult; Aspirin; Cyclic AMP; Dipyridamole; Epoprostenol; Humans; Hypercholesterolemia; In Vitro Techn

1985
Effect of hypercholesterolemia on vascular reactivity in the rabbit. II. Influence of treatment with dipyridamole on endothelium-dependent and endothelium-independent responses in isolated aortas of control and hypercholesterolemic rabbits.
    Circulation research, 1986, Volume: 59, Issue:5

    Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol; Cholesterol, Dietary; Dipyridamole; Hype

1986
[Dipyridamole and lipid metabolism].
    Archivos del Instituto de Farmacologia Experimental (Medicina), 1969, Volume: 21, Issue:1

    Topics: Administration, Oral; Adult; Aged; Dipyridamole; Female; Humans; Hypercholesterolemia; Male; Middle

1969