dipyridamole has been researched along with Edema-Proteinuria-Hypertension Gestosis in 27 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicentric randomized double-blind trial was realized in order to determine whether a treatment with a low-dose aspirin (150 mg/day) with or without dipyridamole (225 mg/day) was able to prevent the perinatal consequences of pre-eclampsia." | 9.07 | Prevention of perinatal consequences of pre-eclampsia with low-dose aspirin: results of the epreda trial. The Epreda Trial Study Group. ( Sureau, C, 1991) |
| "A multicentric randomized double-blind trial was realized in order to determine whether a treatment with a low-dose aspirin (150 mg/day) with or without dipyridamole (225 mg/day) was able to prevent the perinatal consequences of pre-eclampsia." | 5.07 | Prevention of perinatal consequences of pre-eclampsia with low-dose aspirin: results of the epreda trial. The Epreda Trial Study Group. ( Sureau, C, 1991) |
| "102 patients at high risk of pre-eclampsia and/or fetal growth retardation were randomly allocated to treatment with 300 mg dipyridamole and 150 mg aspirin daily from 3 months' gestation onwards (group A) or to the control group (group B, no treatment)." | 5.05 | Prevention of pre-eclampsia by early antiplatelet therapy. ( Beaufils, M; Colau, JC; Donsimoni, R; Uzan, S, 1985) |
| "A woman who had lost two babies, each pregnancy being complicated by eclampsia, and one pregnancy resulting in renal failure; was treated in her fourth pregnancy with heparin and dipyridamole from early pregnancy." | 3.67 | Prevention of pre-eclampsia by early antiplatelet therapy. ( Bickerstaffe, R; McGarry, J, 1987) |
| "In four patients with clinical and laboratory manifestations of the hemolytic-uremic syndrome, the administration of aspirin and dipyridamole was associated with a dramatic and rapid increase in the platelet count." | 3.66 | The treatment of the hemolytic-uremic syndrome with inhibitors of platelet function. ( Carone, FA; Green, D; Rossi, EC; Thorsen, CA, 1979) |
| "The pregnancy was normal in 54% of patients in group A and 23% in group B (p less than 0." | 2.65 | [Controlled trial of preventive treatment of preeclampsia. Preliminary results]. ( Beaufils, M; Colau, JC; Donsimoni, R; Uzan, S, 1984) |
| "Spontaneous preterm birth is an important cause of neonatal mortality and morbidity." | 2.55 | Antiplatelet Agents and the Prevention of Spontaneous Preterm Birth: A Systematic Review and Meta-analysis. ( Askie, LA; Mol, BWJ; Oudijk, MA; van Vliet, EOG, 2017) |
| "Aspirin (ASS) was the most frequently used drug in 47 of 93 recorded cases (51%)." | 2.39 | Essential thrombocythemia and pregnancy. ( Griesshammer, M; Heimpel, H; Pearson, TC, 1996) |
| "Plasmic 6-keto-PGF1a was low." | 1.32 | [Endothelium and platelets in pregnant women with chronic glomerulonephritis and therapeutic efficacy of acetylsalicylic acid and dipiridamol]. ( Artem'eva, VB; Gordovskaia, NB; Kozlovskaia, NL; Krylova, MIu; Rogov, VA; Shilov, EM; Sidorova, IS, 2004) |
| "Women on aspirin, who developed preeclampsia, delivered later in pregnancy [35." | 1.29 | Prevention of preeclampsia with heparin and antiplatelet drugs in women with renal disease. ( Fairley, KF; Ferrier, C; Gamble, G; Kincaid-Smith, P; North, RA, 1995) |
| "In women with fatal eclampsia, disseminated intravascular coagulation with fibrin deposition in the renal glomeruli is well documented." | 1.26 | The role of coagulation and fibrinolysis in preeclampsia. ( Bonnar, J; Denson, KW; Redman, CW, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (55.56) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ray, A | 1 |
| Ray, S | 1 |
| Dodd, JM | 2 |
| McLeod, A | 2 |
| Windrim, RC | 2 |
| Kingdom, J | 2 |
| van Vliet, EOG | 1 |
| Askie, LA | 1 |
| Mol, BWJ | 1 |
| Oudijk, MA | 1 |
| Rogov, VA | 1 |
| Shilov, EM | 1 |
| Kozlovskaia, NL | 1 |
| Gordovskaia, NB | 1 |
| Sidorova, IS | 1 |
| Krylova, MIu | 1 |
| Artem'eva, VB | 1 |
| Beaufils, M | 4 |
| Uzan, S | 4 |
| Donsimoni, R | 3 |
| Colau, JC | 3 |
| Vandekerckhove, F | 1 |
| Noens, L | 1 |
| Colardyn, F | 1 |
| Thiery, M | 1 |
| Delbarge, W | 1 |
| Fournie, A | 1 |
| Boneu, B | 1 |
| Díaz de León-Ponce, M | 1 |
| Méndez-López-Llera, M | 1 |
| Espinoza-Morales, ML | 1 |
| Rubio-Linares, G | 1 |
| North, RA | 1 |
| Ferrier, C | 1 |
| Gamble, G | 1 |
| Fairley, KF | 2 |
| Kincaid-Smith, P | 2 |
| Griesshammer, M | 1 |
| Heimpel, H | 1 |
| Pearson, TC | 1 |
| Patrono, C | 1 |
| Coller, B | 1 |
| Dalen, JE | 1 |
| FitzGerald, GA | 1 |
| Fuster, V | 1 |
| Gent, M | 1 |
| Hirsh, J | 1 |
| Roth, G | 1 |
| Thorsen, CA | 1 |
| Rossi, EC | 1 |
| Green, D | 1 |
| Carone, FA | 1 |
| Carozzi, S | 1 |
| Molinelli, G | 1 |
| Lamperi, S | 1 |
| Bonnar, J | 2 |
| Redman, CW | 1 |
| Denson, KW | 1 |
| Díaz de León Ponce, M | 1 |
| López-Llera, M | 1 |
| Rubio Linares, G | 1 |
| Howie, PW | 1 |
| Prentice, CR | 1 |
| Forbes, CD | 1 |
| Bréart, G | 1 |
| Uzan, M | 1 |
| Paris, J | 1 |
| Reubinoff, BE | 1 |
| Eldor, A | 1 |
| Laufer, N | 1 |
| Sadovsky, E | 1 |
| Ito, M | 1 |
| Ushijima, H | 1 |
| Aiko, A | 1 |
| Nakamura, T | 1 |
| Yoshimura, T | 1 |
| Okamura, H | 1 |
| Sureau, C | 1 |
| Capetta, P | 1 |
| Airoldi, ML | 1 |
| Tasca, A | 1 |
| Bertulessi, C | 1 |
| Rossi, E | 1 |
| Polvani, F | 1 |
| McGarry, J | 1 |
| Bickerstaffe, R | 1 |
| Laver, MC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Placebo-Controlled, Double-Blind, Randomized Study of the Potential Interaction Between Aspirin and Ibuprofen or Celecoxib.[NCT00565500] | Phase 4 | 24 participants (Actual) | Interventional | 2003-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for dipyridamole and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Epidural therapy for the treatment of severe pre-eclampsia in non labouring women.
Topics: Adrenal Cortex Hormones; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Anticonv | 2017 |
Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction.
Topics: Aspirin; Dipyridamole; Eclampsia; Female; Fibrinolytic Agents; Heparin; Humans; Infant; Infant, Low | 2013 |
Antiplatelet Agents and the Prevention of Spontaneous Preterm Birth: A Systematic Review and Meta-analysis.
Topics: Adult; Aspirin; Dipyridamole; Female; Gestational Age; Humans; Logistic Models; Platelet Aggregation | 2017 |
Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction.
Topics: Dipyridamole; Eclampsia; Female; Fibrinolytic Agents; Heparin; Humans; Infant; Infant, Low Birth Wei | 2010 |
Essential thrombocythemia and pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Aspirin; Busulfan; Combined Modality Therapy; Di | 1996 |
Platelet-active drugs : the relationships among dose, effectiveness, and side effects.
Topics: Aspirin; Cyclooxygenase Inhibitors; Dipyridamole; Female; Fibrinolytic Agents; Humans; Platelet Aggr | 2001 |
6 trials available for dipyridamole and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
[Controlled trial of preventive treatment of preeclampsia. Preliminary results].
Topics: Adult; Aspirin; Blood Volume; Clinical Trials as Topic; Dipyridamole; Female; Fetal Growth Retardati | 1984 |
[Prevention of intrauterine growth retardation and pre-eclampsia by small doses of aspirin. Results of the french multicenter trial EPREDA and comparison with data in the literature; value of uterine Doppler].
Topics: Aspirin; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Female; Fetal Growth Retardat | 1992 |
[The effects of dipyridamole on proteinuria in preeclampsia].
Topics: Adult; Dipyridamole; Female; Humans; Pre-Eclampsia; Pregnancy; Proteinuria | 1992 |
Prevention of perinatal consequences of pre-eclampsia with low-dose aspirin: results of the epreda trial. The Epreda Trial Study Group.
Topics: Abruptio Placentae; Aspirin; Birth Weight; Dipyridamole; Double-Blind Method; Drug Combinations; Fem | 1991 |
Prevention of pre-eclampsia by early antiplatelet therapy.
Topics: Adult; Aspirin; Dipyridamole; Female; Humans; Pre-Eclampsia; Pregnancy | 1985 |
Prospective controlled study of early antiplatelet therapy in prevention of preeclampsia.
Topics: Adult; Aspirin; Clinical Trials as Topic; Dipyridamole; Female; Fetal Growth Retardation; Humans; Pa | 1986 |
15 other studies available for dipyridamole and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
[Endothelium and platelets in pregnant women with chronic glomerulonephritis and therapeutic efficacy of acetylsalicylic acid and dipiridamol].
Topics: Administration, Oral; Aspirin; Biomarkers; Blood Platelets; Dipyridamole; Embryo Loss; Endothelium; | 2004 |
Thrombotic thrombocytopenic purpura mimicking toxemia of pregnancy.
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Diagnosis, Differential; Dipyridamole; Female; Fetal Death; | 1984 |
Hemostasis, Prostacyclin and Preeclampsia.
Topics: Aspirin; Dipyridamole; Epoprostenol; Female; Hemostasis; Humans; Imidazoles; Pre-Eclampsia; Pregnanc | 1982 |
Antithrombotic medication in the treatment of acute renal failure in toxemia of pregnancy.
Topics: Acute Kidney Injury; Adult; Blood Coagulation; Blood Coagulation Tests; Blood Pressure; Dipyridamole | 1980 |
Prevention of preeclampsia with heparin and antiplatelet drugs in women with renal disease.
Topics: Adult; Anticoagulants; Aspirin; Dipyridamole; Female; Heparin; Humans; Kidney Diseases; Platelet Agg | 1995 |
The treatment of the hemolytic-uremic syndrome with inhibitors of platelet function.
Topics: Adult; Aspirin; Blood Platelets; Cell Count; Dipyridamole; Female; Hemolytic-Uremic Syndrome; Humans | 1979 |
[Fibrin-fibrinogen degradation products in the urine during pregnancy and puerperium].
Topics: Dipyridamole; Female; Fibrin Fibrinogen Degradation Products; Heparin; Humans; Postpartum Period; Pr | 1979 |
The role of coagulation and fibrinolysis in preeclampsia.
Topics: Blood Cell Count; Blood Coagulation; Blood Platelets; Dipyridamole; Disseminated Intravascular Coagu | 1976 |
[Acute renal insufficiency with high urine output in preeclampsia and in eclampsia].
Topics: Acute Kidney Injury; Dipyridamole; Disseminated Intravascular Coagulation; Eclampsia; Female; Humans | 1975 |
Failure of heparin therapy to affect the clinical course of severe pre-eclampsia.
Topics: Blood Cell Count; Blood Coagulation Tests; Blood Platelets; Dipyridamole; Disseminated Intravascular | 1975 |
Maternal hemorrhagic complications following prophylactic low-dose aspirin and dipyridamole therapy.
Topics: Adult; Aspirin; Bleeding Time; Blood Component Transfusion; Blood Transfusion; Dipyridamole; Drug Th | 1992 |
Prevention of pre-eclampsia and placental insufficiency.
Topics: Dipyridamole; Drug Therapy, Combination; Female; Heparin; Humans; Infant, Newborn; Placenta Diseases | 1986 |
Prevention of pre-eclampsia by early antiplatelet therapy.
Topics: Adult; Blood Pressure; Dipyridamole; Drug Therapy, Combination; Female; Heparin; Humans; Pre-Eclamps | 1987 |
Blood coagulation and fibrinolysis in human pregnancy.
Topics: Abruptio Placentae; Blood Coagulation; Blood Coagulation Factors; Dipyridamole; Disseminated Intrava | 1973 |
Dipyridamole and anticoagulants in renal disease due to glomerular and vascular lesions. A new approach to therapy.
Topics: Acute Kidney Injury; Adolescent; Adult; Anticoagulants; Collagen Diseases; Coumarins; Dipyridamole; | 1970 |