dipyridamole has been researched along with Drug Withdrawal Symptoms in 8 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dipyridamole, a blocker of adenosine reuptake, induced a significant reduction of morphine dependence." | 3.75 | Functional interaction between purinergic system and opioid withdrawal: in vitro evidence. ( Capasso, A; Gallo, C, 2009) |
| "Adenosine A1 receptors were not desensitized, because the potency of the metabolically stable adenosine analog N6-cyclopentyl-adenosine was unchanged after chronic cocaine withdrawal." | 1.30 | Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. ( Bockaert, J; Manzoni, O; Pujalte, D; Williams, J, 1998) |
| "Theophylline pretreatment prior to acute ethanol administration markedly reduced the duration of ethanol-induced sleep and similarly decreased the intensity and duration of motor incoordination." | 1.27 | Possible role of adenosine in the CNS effects of ethanol. ( Dar, MS; Mustafa, SJ; Wooles, WR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Capasso, A | 2 |
| Gallo, C | 1 |
| Foubert, L | 1 |
| De Wolf, D | 1 |
| Mareels, K | 1 |
| Van Belleghem, Y | 1 |
| Reyntjens, K | 1 |
| Mortier, E | 1 |
| Van Nooten, G | 1 |
| Hack, SP | 1 |
| Vaughan, CW | 1 |
| Christie, MJ | 1 |
| Dar, MS | 1 |
| Mustafa, SJ | 1 |
| Wooles, WR | 1 |
| al-Alaiyan, S | 1 |
| al-Omran, A | 1 |
| Dyer, D | 1 |
| Ivy, DD | 1 |
| Kinsella, JP | 1 |
| Ziegler, JW | 1 |
| Abman, SH | 1 |
| Manzoni, O | 1 |
| Pujalte, D | 1 |
| Williams, J | 1 |
| Bockaert, J | 1 |
8 other studies available for dipyridamole and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor | 2009 |
Intravenous dipyridamole enhances the effects of inhaled nitric oxide and prevents rebound pulmonary hypertension in piglets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiestera | 2002 |
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Re | 2003 |
Possible role of adenosine in the CNS effects of ethanol.
Topics: Adenosine; Alcoholic Intoxication; Alcoholism; Animals; Body Temperature; Central Nervous System; Di | 1983 |
The use of phosphodiesterase inhibitor (dipyridamole) to wean from inhaled nitric oxide.
Topics: Administration, Inhalation; Blood Gas Analysis; Dipyridamole; Hemodynamics; Humans; Infant, Newborn; | 1996 |
Dipyridamole attenuates rebound pulmonary hypertension after inhaled nitric oxide withdrawal in postoperative congenital heart disease.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Inhalation; Adolescent; Child, Preschool; Dipyr | 1998 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyri | 1998 |
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; | 2000 |