dipyridamole has been researched along with Disease Exacerbation in 22 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dipyridamole 75 mg was administered orally three times daily during the FU administration." | 6.73 | Phase II trial of infusional fluorouracil, leucovorin, mitomycin, and dipyridamole in locally advanced unresectable pancreatic adenocarcinoma: SWOG S9700. ( Barstis, JJ; Bendetti, JK; Isacoff, WH; Jazieh, AR; Macdonald, JS; Philip, PA, 2007) |
| "Children with IgA nephropathy showing diffuse (>80%) mesangial proliferation are at high risk for end-stage renal failure (ESRF)." | 3.85 | Long-term results of a randomized controlled trial in childhood IgA nephropathy. ( Hataya, H; Honda, M; Iijima, K; Ishikura, K; Ito, S; Kamei, K; Nakanishi, K; Saito, M; Sako, M; Yoshikawa, N, 2011) |
| "Dipyridamole is a widely prescribed drug in ischemic disorders, and it is here investigated for potential clinical use as a new treatment for breast cancer." | 3.79 | Dipyridamole prevents triple-negative breast-cancer progression. ( Bello, AM; De Martino, D; De Vita, G; Di Dato, V; Marino, N; Marshall, JC; Medaglia, C; Navas, L; Romano, A; Scoppettuolo, MN; Spano, D; Steeg, PS; Zollo, M, 2013) |
| "Dipyridamole 75 mg was administered orally three times daily during the FU administration." | 2.73 | Phase II trial of infusional fluorouracil, leucovorin, mitomycin, and dipyridamole in locally advanced unresectable pancreatic adenocarcinoma: SWOG S9700. ( Barstis, JJ; Bendetti, JK; Isacoff, WH; Jazieh, AR; Macdonald, JS; Philip, PA, 2007) |
| "The early stage of progressive IgA nephropathy was defined as having moderate proteinuria between 1 and 2 g/day, creatinine clearance values of 70 ml/min or more, and a histological severity score of 7 or more." | 2.68 | Steroid therapy during the early stage of progressive IgA nephropathy. A 10-year follow-up study. ( Hiki, Y; Horii, A; Kobayashi, Y; Kokubo, T; Tateno, S, 1996) |
| "We enrolled 35 patients with MPGN type 1 who had a normal creatinine clearance at the time of their first renal biopsy and divided them into 2 groups based on clinical status at the time of their most recent examination: 12 patients with normal urine test results and 12 patients with minor urinary abnormalities at the latest observation (group 1) and 7 patients with persistent nephropathy and 4 patients with renal insufficiency (group 2)." | 1.33 | Myeloid-related protein 8 expression on macrophages is a useful prognostic marker for renal dysfunction in children with MPGN type 1. ( Hosoya, M; Isome, M; Kawasaki, Y; Suzuki, H; Takahashi, A; Tanji, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 10 (45.45) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Pezel, T | 1 |
| Hovasse, T | 1 |
| Kinnel, M | 1 |
| Unterseeh, T | 1 |
| Champagne, S | 1 |
| Toupin, S | 1 |
| Garot, P | 1 |
| Sanguineti, F | 1 |
| Garot, J | 1 |
| Wang, C | 1 |
| Schwab, LP | 1 |
| Fan, M | 1 |
| Seagroves, TN | 1 |
| Buolamwini, JK | 1 |
| Guitart, X | 1 |
| Chern, Y | 1 |
| Ferré, S | 1 |
| Kamei, K | 1 |
| Nakanishi, K | 2 |
| Ito, S | 1 |
| Saito, M | 1 |
| Sako, M | 1 |
| Ishikura, K | 2 |
| Hataya, H | 2 |
| Honda, M | 2 |
| Iijima, K | 2 |
| Yoshikawa, N | 2 |
| Sanfiorenzo, C | 1 |
| Pipet, A | 1 |
| Spano, D | 1 |
| Marshall, JC | 1 |
| Marino, N | 1 |
| De Martino, D | 1 |
| Romano, A | 1 |
| Scoppettuolo, MN | 1 |
| Bello, AM | 1 |
| Di Dato, V | 1 |
| Navas, L | 1 |
| De Vita, G | 1 |
| Medaglia, C | 1 |
| Steeg, PS | 1 |
| Zollo, M | 1 |
| Ascione, L | 1 |
| Carlomagno, G | 1 |
| Sordelli, C | 1 |
| Iengo, R | 1 |
| Monda, V | 1 |
| Severino, S | 1 |
| Merenda, R | 1 |
| D'Andrea, A | 1 |
| Caso, P | 1 |
| de Jong, RM | 1 |
| Blanksma, PK | 1 |
| Cornel, JH | 1 |
| Van den Heuvel, AF | 1 |
| Siebelink, HM | 1 |
| Vaalburg, W | 1 |
| van Veldhuisen, DJ | 1 |
| Aslanyan, S | 1 |
| Fazekas, F | 1 |
| Weir, CJ | 1 |
| Horner, S | 1 |
| Lees, KR | 1 |
| Buranakarl, C | 1 |
| Kitjtawonrat, A | 1 |
| Pondeenana, S | 1 |
| Sunyasujaree, B | 1 |
| Kanchanapangka, S | 1 |
| Chaiyabutr, N | 1 |
| Bovee, KC | 1 |
| Kawasaki, Y | 1 |
| Hosoya, M | 1 |
| Takahashi, A | 1 |
| Isome, M | 1 |
| Tanji, M | 1 |
| Suzuki, H | 1 |
| Locatelli, F | 1 |
| Vecchio, LD | 1 |
| Pozzi, C | 1 |
| Dieker, HJ | 1 |
| French, JK | 1 |
| Joziasse, IC | 1 |
| Brouwer, MA | 1 |
| Elliott, J | 1 |
| West, TM | 1 |
| Webber, BJ | 1 |
| Verheugt, FW | 1 |
| White, HD | 1 |
| Isacoff, WH | 1 |
| Bendetti, JK | 1 |
| Barstis, JJ | 1 |
| Jazieh, AR | 1 |
| Macdonald, JS | 1 |
| Philip, PA | 1 |
| Gould, KL | 1 |
| Köhne, CH | 1 |
| Hiddemann, W | 1 |
| Schüller, J | 1 |
| Weiss, J | 1 |
| Lohrmann, HP | 1 |
| Schmitz-Hübner, U | 1 |
| Bodenstein, H | 1 |
| Schöber, C | 1 |
| Wilke, H | 1 |
| Grem, J | 1 |
| Futrakul, P | 1 |
| Futrakul, N | 1 |
| Sitprija, V | 1 |
| Sensirivatana, R | 1 |
| Watana, D | 1 |
| Kingwatanakul, P | 1 |
| Kobayashi, Y | 1 |
| Hiki, Y | 1 |
| Kokubo, T | 1 |
| Horii, A | 1 |
| Tateno, S | 1 |
| Gottsauner-Wolf, M | 1 |
| Sochor, H | 1 |
| Moertl, D | 1 |
| Gwechenberger, M | 1 |
| Stockenhuber, F | 1 |
| Probst, P | 1 |
| Zelger, B | 1 |
| Neglia, D | 1 |
| Michelassi, C | 1 |
| Trivieri, MG | 1 |
| Sambuceti, G | 1 |
| Giorgetti, A | 1 |
| Pratali, L | 1 |
| Gallopin, M | 1 |
| Salvadori, P | 1 |
| Sorace, O | 1 |
| Carpeggiani, C | 1 |
| Poddighe, R | 1 |
| L'Abbate, A | 1 |
| Parodi, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Trial of Infusional 5-Fluorouracil (5-FU), Calcium Leucovorin (LV), Mitomycin-C (Mito-C), and Dipyridamole (D) in Patients With Locally Advanced Unresected Pancreatic Adenocarcinoma[NCT00003018] | Phase 2 | 54 participants (Actual) | Interventional | 1997-09-30 | Completed | ||
| The Impact of Coronary Revascularization on Absolute Myocardial Blood Flow as Assessed by Stress Myocardial Positron Tomography[NCT02931331] | 50 participants (Anticipated) | Observational [Patient Registry] | 2016-03-31 | Enrolling by invitation | |||
| Pilot Study on the Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis[NCT00940862] | Phase 4 | 30 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for dipyridamole and Disease Exacerbation
| Article | Year |
|---|---|
Long-term results of a randomized controlled trial in childhood IgA nephropathy.
Topics: Adolescent; Anticoagulants; Azathioprine; Cell Proliferation; Child; Dipyridamole; Disease Progressi | 2011 |
[Exacerbations of asthma--precipitating factors: drugs].
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Contraindications; Dip | 2011 |
IgA glomerulonephritis: beyond angiotensin-converting enzyme inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Dipyridamole; Disease Progression; Drug Therapy, Combinati | 2006 |
Positron emission tomography in coronary artery disease.
Topics: Calcinosis; Coronary Artery Disease; Coronary Vessels; Dipyridamole; Disease Progression; Humans; Pa | 2007 |
Positron emission tomography in coronary artery disease.
Topics: Calcinosis; Coronary Artery Disease; Coronary Vessels; Dipyridamole; Disease Progression; Humans; Pa | 2007 |
Positron emission tomography in coronary artery disease.
Topics: Calcinosis; Coronary Artery Disease; Coronary Vessels; Dipyridamole; Disease Progression; Humans; Pa | 2007 |
Positron emission tomography in coronary artery disease.
Topics: Calcinosis; Coronary Artery Disease; Coronary Vessels; Dipyridamole; Disease Progression; Humans; Pa | 2007 |
6 trials available for dipyridamole and Disease Exacerbation
| Article | Year |
|---|---|
Long-term results of a randomized controlled trial in childhood IgA nephropathy.
Topics: Adolescent; Anticoagulants; Azathioprine; Cell Proliferation; Child; Dipyridamole; Disease Progressi | 2011 |
Antiplatelet therapy and progression of coronary artery disease: a placebo-controlled trial with angiographic and clinical follow-up after myocardial infarction.
Topics: Aspirin; Coronary Angiography; Coronary Disease; Dipyridamole; Disease Progression; Drug Therapy, Co | 2007 |
Phase II trial of infusional fluorouracil, leucovorin, mitomycin, and dipyridamole in locally advanced unresectable pancreatic adenocarcinoma: SWOG S9700.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dipy | 2007 |
Combination therapy with mizoribine for severe childhood IgA nephropathy: a pilot study.
Topics: Biopsy; Child; Dipyridamole; Disease Progression; Female; Follow-Up Studies; Glomerulonephritis, IGA | 2008 |
Failure of orally administered dipyridamole to enhance the antineoplastic activity of fluorouracil in combination with leucovorin in patients with advanced colorectal cancer: a prospective randomized trial.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neopla | 1995 |
Steroid therapy during the early stage of progressive IgA nephropathy. A 10-year follow-up study.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dipyridamole; Disease Prog | 1996 |
13 other studies available for dipyridamole and Disease Exacerbation
| Article | Year |
|---|---|
Prognostic value of stress cardiovascular magnetic resonance in asymptomatic patients with known coronary artery disease.
Topics: Aged; Asymptomatic Diseases; Coronary Artery Disease; Dipyridamole; Disease Progression; Female; Hum | 2021 |
Chemoprevention activity of dipyridamole in the MMTV-PyMT transgenic mouse model of breast cancer.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Proliferation; Dipyridamole; Disease | 2013 |
Targeting the equilibrative nucleoside transporter ENT1 in Huntington disease.
Topics: Age of Onset; Animals; Animals, Genetically Modified; Biomarkers; Brain; Carrier Proteins; Corpus St | 2017 |
Dipyridamole prevents triple-negative breast-cancer progression.
Topics: Animals; Apoptosis; beta Catenin; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Cycle; Ce | 2013 |
Dipyridamole coronary flow reserve stratifies prognosis in acute coronary syndrome patients without left anterior descending disease.
Topics: Acute Coronary Syndrome; Coronary Angiography; Dipyridamole; Disease Progression; Echocardiography, | 2013 |
Endothelial dysfunction and reduced myocardial perfusion reserve in heart failure secondary to coronary artery disease.
Topics: Aged; Case-Control Studies; Chronic Disease; Coronary Disease; Dipyridamole; Disease Progression; En | 2003 |
Effect of blood pressure during the acute period of ischemic stroke on stroke outcome: a tertiary analysis of the GAIN International Trial.
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Brain Isc | 2003 |
Comparison of dipyridamole and fosinopril on renal progression in nephrectomized rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Dipyridamole; Disease Progression; Fosinopril; Ma | 2003 |
Myeloid-related protein 8 expression on macrophages is a useful prognostic marker for renal dysfunction in children with MPGN type 1.
Topics: Adolescent; Aspirin; Biomarkers; Biopsy; Calgranulin A; Calgranulin B; Child; Creatinine; Cyclophosp | 2005 |
Improved renal perfusion prevents disease progression in focal segmental glomerulosclerosis.
Topics: Cilazapril; Dipyridamole; Disease Progression; Glomerulosclerosis, Focal Segmental; Heparin; Humans; | 1995 |
Assessing coronary stenosis. Quantitative coronary angiography versus visual estimation from cine-film or pharmacological stress perfusion images.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Coronary Angiography; Coronary Disease; Corona | 1996 |
[Progression of livedo vasculitis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Dipyridamole; Disease Progression; Female; Huma | 1996 |
Prognostic role of myocardial blood flow impairment in idiopathic left ventricular dysfunction.
Topics: Coronary Circulation; Dipyridamole; Disease Progression; Disease-Free Survival; Female; Follow-Up St | 2002 |