dipyridamole has been researched along with Diabetic Angiopathies in 33 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Diabetic Angiopathies: VASCULAR DISEASES that are associated with DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myocardial ischemia is frequently asymptomatic, thus leading to a late diagnosis and worse prognosis." | 5.34 | Coronary artery disease in asymptomatic type-2 diabetic women. A comparative study between exercise test, cardiopulmonary exercise test, and dipyridamole myocardial perfusion scintigraphy in the identification of ischemia. ( Alves, A; Carvalho, AC; Mastrocolla, L; Meneghelo, R; Paola, AA; Piegas, LS; Rodrigues, F; Smanio, PE; Tebexreni, AS; Thom, A, 2007) |
| " centers, 231 male diabetic patients who had either a recent amputation for gangrene (N = 207) or active gangrene (N = 24) were randomly assigned to a group which received aspirin (325 mg t." | 5.05 | V.A. Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: III. Definitions and review of design and baseline characteristics. ( Abraira, C; Anderson, JW; Bingham, SF; Colwell, JA; Kwaan, HC, 1985) |
| "Dipyridamole/rest technetium 99m sestamibi imaging was performed in 33 patients with type 2 diabetes without a history of coronary artery disease and normal coronary vessels at angiography and in 12 control subjects." | 3.74 | Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries. ( Cuocolo, A; Luongo, L; Pellegrino, T; Petretta, M; Sorrentino, AR; Storto, G, 2007) |
| " Moreover, patients without any history of coronary heart disease and showing a normal resting ECG underwent a bicycle exercise test or a dipyridamole thallium scintigraphy to detect possible silent myocardial ischemia." | 3.69 | Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM. ( Brun, JM; Cohen, M; Gambert, P; Lagrost, L; Petit, JM; Vaillant, G; Vergès, BL, 1997) |
| "The authors analyzed the results of a 2-year study of a course of diabetic microangiopathy on the basis of clinical tests and morphological control over microvessels of skin biopsy specimens from 61 patients with diabetes mellitus, of whom 36 regularly received coronary vasodilators (diamicron, pentoxifylline and dipyridamole)." | 3.67 | [Results of a two-year clinico-morphological study of the natural evolution of diabetic microangiopathy and the efficacy of angioprotective therapy]. ( Frolova, AI; Saltykov, BB; Shubina, OI; Velikov, VK, 1987) |
| "Pravastatin treatment, resulting in decreased LDL oxidation, did not improve myocardial perfusion reserve in subjects with type 1 diabetes." | 2.71 | Effect of pravastatin on low-density lipoprotein oxidation and myocardial perfusion in young adults with type 1 diabetes. ( Ahotupa, M; Janatuinen, T; Knuuti, J; Nuutila, P; Raitakari, OT; Rönnemaa, T; Toikka, JO, 2004) |
| "The dipyridamole-CF ratio was also lower in diabetic patients than in nondiabetic patients (2." | 1.38 | Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease. ( Acampa, W; Capasso, E; Casaretti, L; Cuocolo, A; D'Amore, C; Esposito, G; Esposito, R; Galderisi, M; Gargiulo, P; Leosco, D; Lo Iudice, F; Marciano, C; Perrone-Filardi, P; Rengo, G; Savarese, G, 2012) |
| "Treatment with dipyridamole decreased high glucose-induced osteopontin expression and secretion." | 1.36 | Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells. ( Chi, WM; Hsieh, MS; Lee, HM; Lin, JY; Yu, SC; Zhong, WB, 2010) |
| "Myocardial ischemia is frequently asymptomatic, thus leading to a late diagnosis and worse prognosis." | 1.34 | Coronary artery disease in asymptomatic type-2 diabetic women. A comparative study between exercise test, cardiopulmonary exercise test, and dipyridamole myocardial perfusion scintigraphy in the identification of ischemia. ( Alves, A; Carvalho, AC; Mastrocolla, L; Meneghelo, R; Paola, AA; Piegas, LS; Rodrigues, F; Smanio, PE; Tebexreni, AS; Thom, A, 2007) |
| "Osteoprotegerin (OPG) is an inhibitor of osteoclastogenesis, which has been recently involved in atherosclerosis." | 1.33 | Osteoprotegerin is associated with silent coronary artery disease in high-risk but asymptomatic type 2 diabetic patients. ( Avignon, A; Cristol, JP; Dupuy, AM; Elaerts, S; Piot, C; Sultan, A, 2005) |
| "Nineteen patients with NIDDM and microvascular angina, 18 patients with NIDDM and CAD, and 17 age-matched control subjects were studied." | 1.31 | Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease. ( Nagai, R; Ohtake, T; Ohtomo, K; Shin, WS; Yamada, N; Yang, W; Yokoyama, I; Yonekura, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (33.33) | 18.7374 |
| 1990's | 11 (33.33) | 18.2507 |
| 2000's | 9 (27.27) | 29.6817 |
| 2010's | 2 (6.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindner, O | 1 |
| Burchert, W | 1 |
| Bengel, FM | 1 |
| Zimmermann, R | 1 |
| vom Dahl, J | 1 |
| Schäfer, W | 1 |
| Schober, O | 1 |
| Schäfers, M | 1 |
| Hsieh, MS | 1 |
| Zhong, WB | 1 |
| Yu, SC | 1 |
| Lin, JY | 1 |
| Chi, WM | 1 |
| Lee, HM | 1 |
| Marciano, C | 1 |
| Galderisi, M | 1 |
| Gargiulo, P | 1 |
| Acampa, W | 1 |
| D'Amore, C | 1 |
| Esposito, R | 1 |
| Capasso, E | 1 |
| Savarese, G | 1 |
| Casaretti, L | 1 |
| Lo Iudice, F | 1 |
| Esposito, G | 1 |
| Rengo, G | 1 |
| Leosco, D | 1 |
| Cuocolo, A | 2 |
| Perrone-Filardi, P | 1 |
| De Lorenzo, A | 1 |
| Lima, RS | 1 |
| Siqueira-Filho, AG | 1 |
| Pantoja, MR | 1 |
| Janatuinen, T | 1 |
| Knuuti, J | 1 |
| Toikka, JO | 1 |
| Ahotupa, M | 1 |
| Nuutila, P | 1 |
| Rönnemaa, T | 1 |
| Raitakari, OT | 1 |
| Avignon, A | 1 |
| Sultan, A | 1 |
| Piot, C | 1 |
| Elaerts, S | 1 |
| Cristol, JP | 1 |
| Dupuy, AM | 1 |
| Scognamiglio, R | 1 |
| Negut, C | 1 |
| Ramondo, A | 1 |
| Tiengo, A | 1 |
| Avogaro, A | 1 |
| Storto, G | 1 |
| Pellegrino, T | 1 |
| Sorrentino, AR | 1 |
| Luongo, L | 1 |
| Petretta, M | 1 |
| Smanio, PE | 1 |
| Carvalho, AC | 1 |
| Tebexreni, AS | 1 |
| Thom, A | 1 |
| Rodrigues, F | 1 |
| Meneghelo, R | 1 |
| Mastrocolla, L | 1 |
| Alves, A | 1 |
| Piegas, LS | 1 |
| Paola, AA | 1 |
| Amado, JA | 1 |
| Suárez, M | 1 |
| Vadillo, V | 1 |
| Vidal, JI | 1 |
| Mazo, E | 1 |
| Colwell, JA | 3 |
| Bingham, SF | 2 |
| Abraira, C | 2 |
| Anderson, JW | 2 |
| Kwaan, HC | 2 |
| Saldan, IR | 1 |
| Gendeleka, GF | 1 |
| Gruzina, EA | 1 |
| Paillole, C | 2 |
| Ruiz, J | 1 |
| Juliard, JM | 2 |
| Leblanc, H | 2 |
| Gourgon, R | 2 |
| Passa, P | 2 |
| Bell, DS | 1 |
| Yumuk, VD | 1 |
| Zarich, SW | 3 |
| Cohen, MC | 2 |
| Lane, SE | 3 |
| Mittleman, MA | 2 |
| Nesto, RW | 3 |
| Hill, T | 3 |
| Campbell, D | 2 |
| Lewis, SM | 3 |
| Shimonagata, T | 1 |
| Nanto, S | 1 |
| Hori, M | 1 |
| Ohara, T | 1 |
| Kim, Y | 1 |
| Takano, Y | 1 |
| Sakamoto, K | 1 |
| Kamado, K | 1 |
| Kubori, S | 1 |
| Kusuoka, H | 1 |
| Nishimura, T | 1 |
| Vergès, BL | 1 |
| Lagrost, L | 1 |
| Vaillant, G | 1 |
| Petit, JM | 1 |
| Cohen, M | 1 |
| Gambert, P | 1 |
| Brun, JM | 1 |
| Herlitz, J | 1 |
| Haglid, M | 1 |
| Hartford, M | 1 |
| Karlson, BW | 1 |
| Karlsson, T | 1 |
| Lindelöw, B | 1 |
| Caidahl, K | 1 |
| Curran, PJ | 1 |
| L'Italien, GJ | 1 |
| Vanzetto, G | 1 |
| Halimi, S | 1 |
| Hammoud, T | 1 |
| Fagret, D | 1 |
| Benhamou, PY | 1 |
| Cordonnier, D | 1 |
| Denis, B | 1 |
| Machecourt, J | 1 |
| Yokoyama, I | 1 |
| Yonekura, K | 1 |
| Ohtake, T | 1 |
| Yang, W | 1 |
| Shin, WS | 1 |
| Yamada, N | 1 |
| Ohtomo, K | 1 |
| Nagai, R | 1 |
| Bigi, R | 1 |
| Desideri, A | 1 |
| Cortigiani, L | 1 |
| Bax, JJ | 1 |
| Celegon, L | 1 |
| Fiorentini, C | 1 |
| Zabel Langhennig, R | 1 |
| Paycha, F | 1 |
| Steg, PG | 1 |
| Philippe, L | 1 |
| de la Cruz, JP | 1 |
| Moreno, A | 1 |
| Sanchez de la Cuesta, F | 1 |
| García Campos, J | 1 |
| Watson, FS | 1 |
| Kowalchuk, GJ | 1 |
| Pippin, JJ | 1 |
| Kosinski, EJ | 1 |
| Császár, A | 1 |
| Daróczy, J | 1 |
| Szénási, P | 1 |
| Anda, L | 1 |
| Tóth, L | 1 |
| Hosszúfalusi, N | 1 |
| Karádi, I | 1 |
| Kalabay, L | 1 |
| Romics, L | 1 |
| Baudoin, C | 1 |
| Bousser, MG | 1 |
| Haguenau, M | 1 |
| Lefauconnier, JM | 1 |
| Eschwege, E | 1 |
| Velikov, VK | 1 |
| Shubina, OI | 1 |
| Saltykov, BB | 1 |
| Frolova, AI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Trial to Evaluate the Effects of Two Different Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve in Hypercholesterolemic Patients at Moderate Cardiovascular Risk[NCT02969070] | 28 participants (Actual) | Interventional | 2016-11-30 | Completed | |||
| Assessment of the Additive Value of Multislice Computed Tomographic Angiography of the Coronary Arteries in the Prediction of Acute Cardiac Events in Asymptomatic Individuals With Type II Diabetes Mellitus[NCT00321542] | 793 participants (Actual) | Observational | 2006-09-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dipyridamole and Diabetic Angiopathies
| Article | Year |
|---|---|
[Necrobiosis lipoidica without diabetes mellitus (diagnostic and therapeutic possibilities)].
Topics: Aspirin; Basement Membrane; Capillaries; Diabetic Angiopathies; Diagnosis, Differential; Dipyridamol | 1989 |
Antiplatelet agents and diabetic vascular disease.
Topics: Aspirin; Blood Platelets; Diabetic Angiopathies; Dipyridamole; Humans | 1987 |
5 trials available for dipyridamole and Diabetic Angiopathies
| Article | Year |
|---|---|
Effect of pravastatin on low-density lipoprotein oxidation and myocardial perfusion in young adults with type 1 diabetes.
Topics: Adult; Coronary Circulation; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dipyridamole; Double- | 2004 |
V.A. Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: I. Design, methods, and baseline characteristics.
Topics: Amputation, Surgical; Aspirin; Clinical Trials as Topic; Diabetic Angiopathies; Dipyridamole; Epopro | 1984 |
Routine perioperative dipyridamole 201Tl imaging in diabetic patients undergoing vascular surgery.
Topics: Aged; Diabetic Angiopathies; Dipyridamole; Female; Heart; Heart Diseases; Humans; Male; Monitoring, | 1996 |
Secondary prevention of strokes: role of platelet antiaggregant drugs in diabetic and non-diabetic patients.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetic Angiopathies; Dipyridamole; D | 1985 |
V.A. Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: III. Definitions and review of design and baseline characteristics.
Topics: Amputation, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; | 1985 |
26 other studies available for dipyridamole and Diabetic Angiopathies
| Article | Year |
|---|---|
[Myocardial perfusion scintigraphy 2007 in Germany--results of the query and current status].
Topics: Adenosine; Cardiology; Diabetic Angiopathies; Dipyridamole; Dobutamine; Exercise Test; Germany; Hear | 2009 |
Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells.
Topics: Animals; Antioxidants; Aorta; Biomarkers; Calcinosis; Cells, Cultured; Diabetic Angiopathies; Dipyri | 2010 |
Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease.
Topics: Aged; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Cor | 2012 |
Prevalence and prognostic value of perfusion defects detected by stress technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography in asymptomatic patients with diabetes mellitus and no known coronary artery disease.
Topics: Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic A | 2002 |
Osteoprotegerin is associated with silent coronary artery disease in high-risk but asymptomatic type 2 diabetic patients.
Topics: Adrenergic beta-Agonists; Aged; Biomarkers; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic An | 2005 |
Detection of coronary artery disease in asymptomatic patients with type 2 diabetes mellitus.
Topics: Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Diab | 2006 |
Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries.
Topics: Aged; Blood Flow Velocity; Coronary Artery Disease; Coronary Vessels; Diabetes Mellitus, Type 2; Dia | 2007 |
Coronary artery disease in asymptomatic type-2 diabetic women. A comparative study between exercise test, cardiopulmonary exercise test, and dipyridamole myocardial perfusion scintigraphy in the identification of ischemia.
Topics: Adult; Aged; Aged, 80 and over; Brazil; Chi-Square Distribution; Coronary Angiography; Coronary Arte | 2007 |
[Levels of beta-thromboglobulin in type I diabetes mellitus. Effect of dipyridamole].
Topics: Beta-Globulins; beta-Thromboglobulin; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dipyridamole | 1983 |
[Use of disaggregants in treating diabetic retinopathy].
Topics: Ascorbic Acid; Aspirin; Calcium Dobesilate; Diabetic Angiopathies; Diabetic Retinopathy; Dipyridamol | 1984 |
[Effect of acetylsalicylic acid and dipyridamole on the microcirculatory state of diabetes mellitus patients based on biomicroscopy and rheography data].
Topics: Adolescent; Adult; Aged; Aspirin; Chronic Disease; Conjunctiva; Diabetic Angiopathies; Dipyridamole; | 1983 |
Detection of coronary artery disease in diabetic patients.
Topics: Adult; Aged; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiop | 1995 |
Low incidence of false-positive exercise thallium 201 scintigraphy in a diabetic population.
Topics: Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Dipyridamole; Ex | 1996 |
A case of hypertensive-diabetic cardiomyopathy demonstrating left ventricular wall motion abnormality.
Topics: Cardiomyopathies; Coronary Angiography; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipyridamo | 1996 |
Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM.
Topics: Apolipoproteins A; Biomarkers; Blood Glucose; Blood Pressure; Cerebrovascular Disorders; Cholesterol | 1997 |
Physical activity, dyspnea, and chest pain before and after coronary artery bypass grafting in relation to a history of diabetes.
Topics: Activities of Daily Living; Aspirin; Chest Pain; Coronary Artery Bypass; Diabetic Angiopathies; Dipy | 1998 |
Long-term prognostic value of preoperative dipyridamole thallium imaging and clinical indexes in patients with diabetes mellitus undergoing peripheral vascular surgery.
Topics: Aged; Diabetic Angiopathies; Dipyridamole; Female; Follow-Up Studies; Heart Diseases; Humans; Ischem | 1999 |
Prediction of cardiovascular events in clinically selected high-risk NIDDM patients. Prognostic value of exercise stress test and thallium-201 single-photon emission computed tomography.
Topics: Activities of Daily Living; Aged; Analysis of Variance; Cardiovascular Diseases; Cholesterol; Choles | 1999 |
Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease.
Topics: Adult; Aged; Blood Glucose; Coronary Angiography; Coronary Circulation; Coronary Disease; Diabetes M | 2000 |
Stress echocardiography for risk stratification of diabetic patients with known or suspected coronary artery disease.
Topics: Adrenergic beta-Agonists; Age Factors; Aged; Coronary Disease; Diabetes Complications; Diabetes Mell | 2001 |
[Inhibitors of platelet aggregation in the therapy of arteriosclerosis obliterans].
Topics: Arteriosclerosis Obliterans; Aspirin; Diabetic Angiopathies; Dipyridamole; Humans; Platelet Aggregat | 1979 |
Non-invasive identification of severe coronary artery disease in patients with long-standing diabetes mellitus.
Topics: Coronary Angiography; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabet | 1992 |
Effect of antiplatelet drug therapy on the retinal vascular pattern in experimental diabetes mellitus.
Topics: Animals; Aspirin; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dipyridamole; Dr | 1990 |
Silent myocardial ischemia and infarction in diabetics with peripheral vascular disease: assessment by dipyridamole thallium-201 scintigraphy.
Topics: Adult; Aged; Aged, 80 and over; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diabete | 1990 |
Predictive value of quantitative dipyridamole-thallium scintigraphy in assessing cardiovascular risk after vascular surgery in diabetes mellitus.
Topics: Angina Pectoris; Cardiovascular Diseases; Diabetic Angiopathies; Dipyridamole; Electrocardiography; | 1989 |
[Results of a two-year clinico-morphological study of the natural evolution of diabetic microangiopathy and the efficacy of angioprotective therapy].
Topics: Adolescent; Adult; Aged; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Dipyridam | 1987 |