Page last updated: 2024-10-26

dipyridamole and Diabetes Mellitus, Type 2

dipyridamole has been researched along with Diabetes Mellitus, Type 2 in 35 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
", aspirin alone (330 mg 3 times daily) or in combination with dipyridamole (75 mg 3 times daily), was tested versus placebo in 475 patients with early diabetic retinopathy."9.06Effect of aspirin alone and aspirin plus dipyridamole in early diabetic retinopathy. A multicenter randomized controlled clinical trial. The DAMAD Study Group. ( , 1989)
"We selected parameters (fibrinogen, micro/macroalbuminuria, ateroma in carotid artery bed) that were significantly associated with stress myocardial SPECT result."7.73[The meaning of the combination of fibrinogen, micro/macroalbuminuria and atheromatosis in the carotid bloodstream for the evaluation of the abnormal finding of the stress myocardial SPECT in the asymptomatic 2nd type diabetic patients]. ( Holá, D; Pálová, S; Zamrazil, V, 2006)
"A total of 5308 patients with type 2 diabetes were identified by the National Health Insurance from 1998 to 2000 and followed up until 2013."5.72Antiplatelet agents aspirin and dipyridamole, and the risk of different carcinoma in patients with type 2 diabetes mellitus: A Taiwan retrospective cohort study. ( Hsu, WH; Huang, HY; Lee, MY; Liang, HL; Lu, TW; Sung, YW, 2022)
"Myocardial ischemia is frequently asymptomatic, thus leading to a late diagnosis and worse prognosis."5.34Coronary artery disease in asymptomatic type-2 diabetic women. A comparative study between exercise test, cardiopulmonary exercise test, and dipyridamole myocardial perfusion scintigraphy in the identification of ischemia. ( Alves, A; Carvalho, AC; Mastrocolla, L; Meneghelo, R; Paola, AA; Piegas, LS; Rodrigues, F; Smanio, PE; Tebexreni, AS; Thom, A, 2007)
"In these NIDDM patients without evidence of epicardial coronary disease, endothelial dysfunction is strongly suggested by an impaired increase in CBF both to dipyridamole and to CPT."5.10Dipyridamole, cold pressor test, and demonstration of endothelial dysfunction: a PET study of myocardial perfusion in diabetes. ( Hesse, B; Kjaer, A; Meyer, C; Nielsen, FS; Parving, HH, 2003)
", aspirin alone (330 mg 3 times daily) or in combination with dipyridamole (75 mg 3 times daily), was tested versus placebo in 475 patients with early diabetic retinopathy."5.06Effect of aspirin alone and aspirin plus dipyridamole in early diabetic retinopathy. A multicenter randomized controlled clinical trial. The DAMAD Study Group. ( , 1989)
"Dipyridamole/rest technetium 99m sestamibi imaging was performed in 33 patients with type 2 diabetes without a history of coronary artery disease and normal coronary vessels at angiography and in 12 control subjects."3.74Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries. ( Cuocolo, A; Luongo, L; Pellegrino, T; Petretta, M; Sorrentino, AR; Storto, G, 2007)
"We selected parameters (fibrinogen, micro/macroalbuminuria, ateroma in carotid artery bed) that were significantly associated with stress myocardial SPECT result."3.73[The meaning of the combination of fibrinogen, micro/macroalbuminuria and atheromatosis in the carotid bloodstream for the evaluation of the abnormal finding of the stress myocardial SPECT in the asymptomatic 2nd type diabetic patients]. ( Holá, D; Pálová, S; Zamrazil, V, 2006)
"To clarify if coronary flow reserve (CFR) is related to insulin resistance or hyperglycemia in normotensive NIDDM, myocardial blood flow (MBF) at baseline and during dipyridamole loading were measured with 13N-ammonia positron-emission tomography."3.70Hyperglycemia rather than insulin resistance is related to reduced coronary flow reserve in NIDDM. ( Momomura, S; Nishikawa, J; Ohtake, T; Omata, M; Sasaki, Y; Woo-Soo, S; Yokoyama, I; Yonekura, K, 1998)
" Moreover, patients without any history of coronary heart disease and showing a normal resting ECG underwent a bicycle exercise test or a dipyridamole thallium scintigraphy to detect possible silent myocardial ischemia."3.69Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM. ( Brun, JM; Cohen, M; Gambert, P; Lagrost, L; Petit, JM; Vaillant, G; Vergès, BL, 1997)
"In these patients with type 2 diabetes and a history of TIA, patterns of platelet inhibition differed significantly according to whether treatment was with ER-DP+ASA or clopidogrel with or without ASA."2.73Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-b ( Hanley, DF; Malinin, AI; Pokov, AN; Serebruany, VL, 2008)
"Nineteen consecutive patients with type 2 diabetes and coronary artery disease entered the study."2.70Effects of treatment with sulfonylurea drugs or insulin on ischemia-induced myocardial dysfunction in type 2 diabetes. ( Avogaro, A; Bagolin, E; Negut, C; Palisi, M; Scognamiglio, R; Tiengo, A; Vigili de Kreutzenberg, S, 2002)
"Therefore, glibenclamide treatment of Type 2 diabetes mellitus may have hazardous cardiovascular effects when used under conditions of ischaemia."2.70Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients. ( Abbink, EJ; Jansen van Rosendaal, A; Lutterman, JA; Pickkers, P; Russel, FG; Smits, P; Tack, CJ, 2002)
"Seventy-six patients with type-2 diabetic nephropathy, who had normal renal function tests were randomized into the 4 groups; each group (n = 19) received one of the following treatments: aspirin (1000 mg), dipyridamole (750 mg), their combination or placebo daily for 2 months."2.70A comparative randomized and placebo-controlled short-term trial of aspirin and dipyridamole for overt type-2 diabetic nephropathy. ( Khajehdehi, P; Mostafavi, H; Roozbeh, J, 2002)
"A total of 5308 patients with type 2 diabetes were identified by the National Health Insurance from 1998 to 2000 and followed up until 2013."1.72Antiplatelet agents aspirin and dipyridamole, and the risk of different carcinoma in patients with type 2 diabetes mellitus: A Taiwan retrospective cohort study. ( Hsu, WH; Huang, HY; Lee, MY; Liang, HL; Lu, TW; Sung, YW, 2022)
"The dipyridamole-CF ratio was also lower in diabetic patients than in nondiabetic patients (2."1.38Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease. ( Acampa, W; Capasso, E; Casaretti, L; Cuocolo, A; D'Amore, C; Esposito, G; Esposito, R; Galderisi, M; Gargiulo, P; Leosco, D; Lo Iudice, F; Marciano, C; Perrone-Filardi, P; Rengo, G; Savarese, G, 2012)
"Myocardial ischemia is frequently asymptomatic, thus leading to a late diagnosis and worse prognosis."1.34Coronary artery disease in asymptomatic type-2 diabetic women. A comparative study between exercise test, cardiopulmonary exercise test, and dipyridamole myocardial perfusion scintigraphy in the identification of ischemia. ( Alves, A; Carvalho, AC; Mastrocolla, L; Meneghelo, R; Paola, AA; Piegas, LS; Rodrigues, F; Smanio, PE; Tebexreni, AS; Thom, A, 2007)
"Osteoprotegerin (OPG) is an inhibitor of osteoclastogenesis, which has been recently involved in atherosclerosis."1.33Osteoprotegerin is associated with silent coronary artery disease in high-risk but asymptomatic type 2 diabetic patients. ( Avignon, A; Cristol, JP; Dupuy, AM; Elaerts, S; Piot, C; Sultan, A, 2005)
"The prevalence of type 2 diabetes mellitus is rapidly increasing."1.33Tissue Doppler imaging for the detection and quantitation of myocardial dysfunction in patients with type 2 diabetes mellitus. ( Dounis, V; Hansen, A; Malmberg, K; Rydén, L; Thrainsdottir, IS; Von Bibra, H, 2005)
"An all the patients with left ventricular hypertrophy (LVH) had decreased CFVR whose values with the myocardial mass index above 130 g/m2 were significantly less than those in the absence of LVH."1.32[Coronary flow vasodilator reserve in patients with type 2 diabetes mellitus-associated arterial hypertension]. ( Efimova, EV; Karpov, RS; Koshel'skaia, OA; Ocheredko, NA; Panafidin, AV; Soldatenko, MV, 2004)
"Nineteen patients with NIDDM and microvascular angina, 18 patients with NIDDM and CAD, and 17 age-matched control subjects were studied."1.31Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease. ( Nagai, R; Ohtake, T; Ohtomo, K; Shin, WS; Yamada, N; Yang, W; Yokoyama, I; Yonekura, K, 2000)
"The diazoxide-mediated increase in the forearm blood flow ratio (infused/control arm) was significantly less pronounced after glibenclamide than after acarbose (290 +/- 58% and 561 +/- 101% respectively; P<0."1.31Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes. ( Abbink, EJ; Lutterman, JA; Pickkers, P; Russel, FG; Smits, P; Tack, CJ; van Rosendaal, AJ, 2002)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.71)18.7374
1990's9 (25.71)18.2507
2000's20 (57.14)29.6817
2010's3 (8.57)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Huang, HY1
Lu, TW1
Liang, HL1
Hsu, WH1
Sung, YW1
Lee, MY1
De Lorenzo, A2
Lima, RS2
Lièvre, MM1
Moulin, P1
Thivolet, C1
Rodier, M1
Rigalleau, V1
Penfornis, A1
Pradignac, A1
Ovize, M1
Marciano, C1
Galderisi, M1
Gargiulo, P1
Acampa, W1
D'Amore, C1
Esposito, R1
Capasso, E1
Savarese, G1
Casaretti, L1
Lo Iudice, F1
Esposito, G1
Rengo, G1
Leosco, D1
Cuocolo, A2
Perrone-Filardi, P1
Valentine, N1
Van de Laar, FA1
van Driel, ML1
Siqueira-Filho, AG1
Pantoja, MR1
Kjaer, A1
Meyer, C1
Nielsen, FS1
Parving, HH1
Hesse, B1
Karpov, RS1
Koshel'skaia, OA1
Soldatenko, MV1
Efimova, EV1
Ocheredko, NA1
Panafidin, AV1
Avignon, A2
Sultan, A2
Piot, C2
Elaerts, S1
Cristol, JP1
Dupuy, AM1
Von Bibra, H1
Thrainsdottir, IS1
Hansen, A1
Dounis, V1
Malmberg, K1
Rydén, L1
Scognamiglio, R2
Negut, C2
Ramondo, A1
Tiengo, A2
Avogaro, A2
Lacourcière, Y1
Côté, C1
Lefebvre, J1
Dumont, M1
Mariano-Goulart, D1
Daures, JP1
Comte, F1
Renard, E1
Zamrazil, V1
Pálová, S1
Holá, D1
Storto, G1
Pellegrino, T1
Sorrentino, AR1
Luongo, L1
Petretta, M1
Smanio, PE1
Carvalho, AC1
Tebexreni, AS1
Thom, A1
Rodrigues, F1
Meneghelo, R1
Mastrocolla, L1
Alves, A1
Piegas, LS1
Paola, AA1
Carneiro, FS1
Giachini, FRC1
Lima, VV1
Carneiro, ZN1
Leite, R1
Inscho, EW1
Tostes, RC1
Webb, RC1
Serebruany, VL1
Malinin, AI1
Pokov, AN1
Hanley, DF1
Paillole, C2
Ruiz, J1
Juliard, JM2
Leblanc, H2
Gourgon, R2
Passa, P2
Shimonagata, T1
Nanto, S1
Hori, M1
Ohara, T1
Kim, Y1
Takano, Y1
Sakamoto, K1
Kamado, K1
Kubori, S1
Kusuoka, H1
Nishimura, T1
Vergès, BL1
Lagrost, L1
Vaillant, G1
Petit, JM1
Cohen, M1
Gambert, P1
Brun, JM1
Kranidis, A1
Zamanis, N1
Mitrakou, A1
Patsilinakos, S1
Bouki, T1
Tountas, N1
Anthopoulos, P1
Raptis, S1
Anthopoulos, L1
Yokoyama, I2
Ohtake, T2
Momomura, S1
Yonekura, K2
Woo-Soo, S1
Nishikawa, J1
Sasaki, Y1
Omata, M1
Vanzetto, G1
Halimi, S1
Hammoud, T1
Fagret, D1
Benhamou, PY1
Cordonnier, D1
Denis, B1
Machecourt, J1
Gaddi, O1
Tortorella, G1
Picano, E1
Pantaleoni, M1
Manicardi, E1
Varga, A1
Moneta, I1
Guiducci, U1
Yang, W1
Shin, WS1
Yamada, N1
Ohtomo, K1
Nagai, R1
Castells, I1
Salinas, I1
Rius, F1
Fraile, M1
Rubio, L1
Pereferrer, D1
Romero, R1
Sanmartí, A1
Abbink, EJ2
Pickkers, P2
van Rosendaal, AJ1
Lutterman, JA2
Tack, CJ2
Russel, FG2
Smits, P2
Vigili de Kreutzenberg, S1
Palisi, M1
Bagolin, E1
Jansen van Rosendaal, A1
Khajehdehi, P1
Roozbeh, J1
Mostafavi, H1
Paycha, F1
Steg, PG1
Philippe, L1
Nesto, RW1
Watson, FS1
Kowalchuk, GJ1
Zarich, SW1
Hill, T1
Lewis, SM1
Lane, SE1
Zhu, XX1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Strategy Trial Comparing Detection of Silent Ischemia With no Detection of Silent Ischemia in Asymptomatic Patients With Type 2 Diabetes Mellitus. Effects on Cardiovascular Events.[NCT00627783]642 participants (Actual)Interventional2000-12-31Terminated (stopped due to Poor recruiting status)
Functional and Anatomic Imaging Versus No Testing in Asymptomatic High-risk Diabetic Patients[NCT04388280]400 participants (Anticipated)Interventional2021-01-28Recruiting
Randomized Trial to Evaluate the Effects of Two Different Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve in Hypercholesterolemic Patients at Moderate Cardiovascular Risk[NCT02969070]28 participants (Actual)Interventional2016-11-30Completed
A Phase 2, Investigator-Initiated, Feasibility Study to Evaluate the Mechanisms of Coronary Endothelial Dysfunction Imaged As Resting Myocardial Perfusion Heterogeneity After Endothelin Receptor Blockade With Darusentan[NCT00738049]Phase 240 participants (Actual)Interventional2009-06-30Completed
Improvement of Myocardial Function and Metabolic Syndrome in Type 2 Diabetes Patients by a Low Glycemic and Insulinemic Diet (LOGI®) Compared to the Traditional Low Fat Diet - a Prospective Parallel Group/Cross Over Study[NCT01004757]41 participants (Anticipated)Interventional2008-02-29Active, not recruiting
Assessment of the Additive Value of Multislice Computed Tomographic Angiography of the Coronary Arteries in the Prediction of Acute Cardiac Events in Asymptomatic Individuals With Type II Diabetes Mellitus[NCT00321542]793 participants (Actual)Observational2006-09-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change During Darusentan Treatment in Absolute Flow at Rest and Hyperemia

(NCT00738049)
Timeframe: 0, 2, 4, and 6 weeks

Interventioncc/min/gm (Mean)
Darusentan 100mg at Rest0.65
Darusentan 100mg at Hyperemia1.97
Baseline at Rest0.50
Baseline at Hyperemia2.03

Change During Darusentan Treatment in the Coronary Flow Reserve (CFR)

CFR is calculated as the unitless ratio between hyperemic to resting flow (NCT00738049)
Timeframe: 0, 2, 4, and 6 weeks

Interventionno units (Mean)
Baseline3.52
Darusentan 100mg3.04

Change During Darusentan Treatment in the Markovian Homogeneity Number, a Value That Quantitates Myocardial Perfusion Heterogeneity

Markovian homogeneity analysis characterizes an image produced by a PET scan by examining the probability that a pixel with a given intensity will have a neighbor with a different intensity. The homogeneity index ranges from >0 to 1, where a value near 0 represents an image with a high probability that neighboring pixels have intensity values that differ greatly, and a value near 1 represents an image with a high probability that neighboring pixels have similar intensity values. (NCT00738049)
Timeframe: 0, 2, 4, and 6 weeks

InterventionNo units (Mean)
Baseline0.33
Darusentan 100mg0.39

Reviews

2 reviews available for dipyridamole and Diabetes Mellitus, Type 2

ArticleYear
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2 diabetes mellitus.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus, Type 2; Dipyridamole; Drug Therapy

2012

Trials

7 trials available for dipyridamole and Diabetes Mellitus, Type 2

ArticleYear
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Detection of silent myocardial ischemia in asymptomatic patients with diabetes: results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening.
    Trials, 2011, Jan-26, Volume: 12

    Topics: Aged; Ambulatory Care; Asymptomatic Diseases; Cause of Death; Chi-Square Distribution; Diabetes Comp

2011
Dipyridamole, cold pressor test, and demonstration of endothelial dysfunction: a PET study of myocardial perfusion in diabetes.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Cold Temperature; Coronary Circulation; Coronary Disease;

2003
Antiplatelet profiles of the fixed-dose combination of extended-release dipyridamole and low-dose aspirin compared with clopidogrel with or without aspirin in patients with type 2 diabetes and a history of transient ischemic attack: a randomized, single-b
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adult; Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Biomarkers; Clopidogrel; Diabetes Mell

2008
Effects of treatment with sulfonylurea drugs or insulin on ischemia-induced myocardial dysfunction in type 2 diabetes.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Cardiomyopathies; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipyridamole; Echocardiography, Str

2002
Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients.
    Diabetic medicine : a journal of the British Diabetic Association, 2002, Volume: 19, Issue:2

    Topics: Acetylcholine; Adult; Aged; Blood Flow Velocity; Blood Pressure; Body Mass Index; Body Weight; C-Pep

2002
A comparative randomized and placebo-controlled short-term trial of aspirin and dipyridamole for overt type-2 diabetic nephropathy.
    Scandinavian journal of urology and nephrology, 2002, Volume: 36, Issue:2

    Topics: Adult; Aged; Aspirin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipyridamole; Drug Administ

2002
Effect of aspirin alone and aspirin plus dipyridamole in early diabetic retinopathy. A multicenter randomized controlled clinical trial. The DAMAD Study Group.
    Diabetes, 1989, Volume: 38, Issue:4

    Topics: Adult; Aspirin; Blood Pressure; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellit

1989

Other Studies

27 other studies available for dipyridamole and Diabetes Mellitus, Type 2

ArticleYear
Antiplatelet agents aspirin and dipyridamole, and the risk of different carcinoma in patients with type 2 diabetes mellitus: A Taiwan retrospective cohort study.
    Medicine, 2022, Sep-16, Volume: 101, Issue:37

    Topics: Aspirin; Carcinoma; Diabetes Mellitus, Type 2; Dipyridamole; Humans; Liver Neoplasms; Platelet Aggre

2022
Reduced heart rate response to dipyridamole as a marker of left ventricular dysfunction in diabetic patients undergoing myocardial perfusion scintigraphy.
    Clinical nuclear medicine, 2009, Volume: 34, Issue:5

    Topics: Aged; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipyridamole; Female; Heart Rate; Humans

2009
Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease.
    European journal of nuclear medicine and molecular imaging, 2012, Volume: 39, Issue:7

    Topics: Aged; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Cor

2012
Prevalence and prognostic value of perfusion defects detected by stress technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography in asymptomatic patients with diabetes mellitus and no known coronary artery disease.
    The American journal of cardiology, 2002, Oct-15, Volume: 90, Issue:8

    Topics: Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic A

2002
[Coronary flow vasodilator reserve in patients with type 2 diabetes mellitus-associated arterial hypertension].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:6

    Topics: Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Dipyridamole; Echocardiogr

2004
Osteoprotegerin is associated with silent coronary artery disease in high-risk but asymptomatic type 2 diabetic patients.
    Diabetes care, 2005, Volume: 28, Issue:9

    Topics: Adrenergic beta-Agonists; Aged; Biomarkers; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic An

2005
Tissue Doppler imaging for the detection and quantitation of myocardial dysfunction in patients with type 2 diabetes mellitus.
    Diabetes & vascular disease research, 2005, Volume: 2, Issue:1

    Topics: Age Factors; Aged; Cardiomyopathies; Cardiovascular Agents; Diabetes Mellitus, Type 2; Diastole; Dip

2005
Detection of coronary artery disease in asymptomatic patients with type 2 diabetes mellitus.
    Journal of the American College of Cardiology, 2006, Jan-03, Volume: 47, Issue:1

    Topics: Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Diab

2006
Noninvasive detection of silent coronary artery disease in patients with essential hypertension, alone or associated with type 2 diabetes mellitus, using dipyridamole stress 99mtechnetium-sestamibi myocardial perfusion imaging.
    The Canadian journal of cardiology, 2006, Volume: 22 Suppl A

    Topics: Aged; Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Dipyridamole; Exerci

2006
Myocardial perfusion imaging and cardiac events in a cohort of asymptomatic patients with diabetes living in southern France.
    Diabetic medicine : a journal of the British Diabetic Association, 2006, Volume: 23, Issue:4

    Topics: Aged; Angina Pectoris; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipyr

2006
[The meaning of the combination of fibrinogen, micro/macroalbuminuria and atheromatosis in the carotid bloodstream for the evaluation of the abnormal finding of the stress myocardial SPECT in the asymptomatic 2nd type diabetic patients].
    Vnitrni lekarstvi, 2006, Volume: 52, Issue:2

    Topics: Albuminuria; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Coronary Circulation; Coron

2006
Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2007, Volume: 14, Issue:2

    Topics: Aged; Blood Flow Velocity; Coronary Artery Disease; Coronary Vessels; Diabetes Mellitus, Type 2; Dia

2007
Coronary artery disease in asymptomatic type-2 diabetic women. A comparative study between exercise test, cardiopulmonary exercise test, and dipyridamole myocardial perfusion scintigraphy in the identification of ischemia.
    Arquivos brasileiros de cardiologia, 2007, Volume: 89, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Brazil; Chi-Square Distribution; Coronary Angiography; Coronary Arte

2007
Adenosine actions are preserved in corpus cavernosum from obese and type II diabetic db/db mouse.
    The journal of sexual medicine, 2008, Volume: 5, Issue:5

    Topics: Acetylcholine; Adenosine; Adenosine Kinase; Animals; Diabetes Mellitus, Type 2; Dipyridamole; Diseas

2008
Detection of coronary artery disease in diabetic patients.
    Diabetologia, 1995, Volume: 38, Issue:6

    Topics: Adult; Aged; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiop

1995
A case of hypertensive-diabetic cardiomyopathy demonstrating left ventricular wall motion abnormality.
    Diabetes care, 1996, Volume: 19, Issue:8

    Topics: Cardiomyopathies; Coronary Angiography; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipyridamo

1996
Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM.
    Diabetes, 1997, Volume: 46, Issue:1

    Topics: Apolipoproteins A; Biomarkers; Blood Glucose; Blood Pressure; Cerebrovascular Disorders; Cholesterol

1997
Coronary microcirculation evaluation with transesophageal echocardiography Doppler in type II diabetics.
    International journal of cardiology, 1997, Apr-18, Volume: 59, Issue:2

    Topics: Age Factors; Blood Flow Velocity; Body Mass Index; Case-Control Studies; Coronary Circulation; Coron

1997
Hyperglycemia rather than insulin resistance is related to reduced coronary flow reserve in NIDDM.
    Diabetes, 1998, Volume: 47, Issue:1

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; Coronary Vessels; Diabetes Mellitus, Type 2; Dipyridamol

1998
Prediction of cardiovascular events in clinically selected high-risk NIDDM patients. Prognostic value of exercise stress test and thallium-201 single-photon emission computed tomography.
    Diabetes care, 1999, Volume: 22, Issue:1

    Topics: Activities of Daily Living; Aged; Analysis of Variance; Cardiovascular Diseases; Cholesterol; Choles

1999
Diagnostic and prognostic value of vasodilator stress echocardiography in asymptomatic Type 2 diabetic patients with positive exercise thallium scintigraphy: a pilot study.
    Diabetic medicine : a journal of the British Diabetic Association, 1999, Volume: 16, Issue:9

    Topics: Coronary Angiography; Diabetes Mellitus, Type 2; Dipyridamole; Echocardiography; Exercise Test; Fema

1999
Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2000, Volume: 41, Issue:6

    Topics: Adult; Aged; Blood Glucose; Coronary Angiography; Coronary Circulation; Coronary Disease; Diabetes M

2000
Inducible myocardial ischaemia in asymptomatic Type 2 diabetic patients.
    Diabetes research and clinical practice, 2000, Volume: 49, Issue:2-3

    Topics: Adult; Aged; Albuminuria; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephr

2000
Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes.
    Clinical science (London, England : 1979), 2002, Volume: 102, Issue:3

    Topics: Acarbose; Acetylcholine; Cross-Over Studies; Diabetes Mellitus, Type 2; Diazoxide; Dipyridamole; Dou

2002
Non-invasive identification of severe coronary artery disease in patients with long-standing diabetes mellitus.
    The European journal of medicine, 1992, Volume: 1, Issue:8

    Topics: Coronary Angiography; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabet

1992
Silent myocardial ischemia and infarction in diabetics with peripheral vascular disease: assessment by dipyridamole thallium-201 scintigraphy.
    American heart journal, 1990, Volume: 120, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diabete

1990
[Effect of danshan and persantin on the alteration of platelet aggregation and microcirculation in diabetics].
    Zhonghua nei ke za zhi, 1985, Volume: 24, Issue:4

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Dipyridamole; Drug Combinations; Drugs, Chinese Herbal; Fema

1985