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dipyridamole and Death, Sudden, Cardiac

dipyridamole has been researched along with Death, Sudden, Cardiac in 22 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)

Research Excerpts

ExcerptRelevanceReference
"We assessed the safety of early (2 to 4 days) intravenous dipyridamole infusion in conjunction with technetium 99m sestamibi tomographic myocardial perfusion imaging in patients with first myocardial infarction (MI)."9.08Safety of early intravenous dipyridamole technetium 99m sestamibi SPECT myocardial perfusion imaging after uncomplicated first myocardial infarction. Early Post MI IV Dipyridamole Study (EPIDS). ( Brown, KA; Haber, SB; Heller, GV; Landin, RJ, 1997)
"To assess the utility of intravenous dipyridamole thallium testing for predicting major cardiac events following acute myocardial infarction in older patients."7.70Prognostic value of dipyridamole thallium imaging after acute myocardial infarction in older patients. ( Baird, JB; Fischer, KC; Jain, S; Rich, MW, 1999)
"We assessed the safety of early (2 to 4 days) intravenous dipyridamole infusion in conjunction with technetium 99m sestamibi tomographic myocardial perfusion imaging in patients with first myocardial infarction (MI)."5.08Safety of early intravenous dipyridamole technetium 99m sestamibi SPECT myocardial perfusion imaging after uncomplicated first myocardial infarction. Early Post MI IV Dipyridamole Study (EPIDS). ( Brown, KA; Haber, SB; Heller, GV; Landin, RJ, 1997)
"The aim of the study was to evaluate the prognostic value of Doppler echocardiographic-derived coronary flow reserve (CFR) over regional wall motion in patients with known or suspected coronary artery disease (CAD) undergoing dipyridamole echocardiography test (DET)."3.74The additive prognostic value of wall motion abnormalities and coronary flow reserve during dipyridamole stress echo. ( Cortigiani, L; Djordjevic-Dikic, A; Gherardi, S; Picano, E; Rigo, F; Sicari, R, 2008)
"To assess the utility of intravenous dipyridamole thallium testing for predicting major cardiac events following acute myocardial infarction in older patients."3.70Prognostic value of dipyridamole thallium imaging after acute myocardial infarction in older patients. ( Baird, JB; Fischer, KC; Jain, S; Rich, MW, 1999)
" The current study was performed to examine whether sex-specific differences exist in these outcomes in a large population of vascular surgery patients and to determine the value of clinical and dipyridamole thallium variables in predicting myocardial infarction and cardiac death."3.69Sex differences in perioperative and long-term cardiac event-free survival in vascular surgery patients. An analysis of clinical and scintigraphic variables. ( Chen, MH; Eagle, KA; Hendel, RC; L'Italien, GJ; Leppo, JA; Newell, JB; Paul, SD, 1995)
"Dipyridamole was not more efficacious in the prevention of vascular death (relative risk [RR], 1."2.42Cochrane review: dipyridamole for preventing major vascular events in patients with vascular disease. ( Algra, A; De Schryver, EL; van Gijn, J, 2003)
"A dipyridamole study was recommended instead of exercise because of arthritis, severe obesity, peripheral vascular disease, pulmonary disease, other chronic illnesses, or combinations of these problems."1.28Long-term prognostic value of a normal dipyridamole thallium-201 perfusion scan. ( Gal, RA; Gunasekera, J; Massardo, T; Port, SC; Shalev, Y, 1991)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (63.64)18.2507
2000's6 (27.27)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carboni, GP1
Sedati, P1
De Marco, E1
Mathur, S1
Shah, AR1
Ahlberg, AW1
Katten, DM1
Heller, GV4
Ishikawa, K1
De Schryver, EL1
Algra, A1
van Gijn, J1
Saya, S1
Hennebry, TA1
Lozano, P1
Lazzara, R1
Schechter, E1
Rigo, F1
Sicari, R1
Gherardi, S1
Djordjevic-Dikic, A1
Cortigiani, L1
Picano, E1
Hendel, RC2
Chen, MH1
L'Italien, GJ1
Newell, JB1
Paul, SD1
Eagle, KA1
Leppo, JA2
Chikamori, T1
Doi, YL1
Yamada, M1
Takata, J1
Yonezawa, Y1
Ozawa, T1
Brown, KA2
Rowen, M1
McPhail, NV1
Ruddy, TD1
Barber, GG1
Cole, CW1
Marois, LJ1
Gulenchyn, KY1
Stratmann, HG1
Younis, LT1
Wittry, MD1
Amato, M1
Mark, AL1
Miller, DD1
Kontos, MC1
Brath, LK1
Akosah, KO1
Mohanty, PK1
de Virgilio, C1
Pak, S1
Arnell, T1
Donayre, C1
Lewis, RJ1
Stabile, BE1
White, R1
McClellan, JR1
Travin, MI2
Herman, SD2
Baron, JI1
Golub, RJ1
Gallagher, JJ1
Waters, D1
Duca, MD1
Kline, GM1
Demus, DD1
Landin, RJ1
Haber, SB1
Jain, S1
Baird, JB1
Fischer, KC1
Rich, MW1
Vanzetto, G1
Halimi, S1
Hammoud, T1
Fagret, D1
Benhamou, PY1
Cordonnier, D1
Denis, B1
Machecourt, J1
Chapelon-Abric, C1
Baron, BW1
Martin, MS1
Sucharetza, BS1
Jeon, H1
Baron, JM1
Whitfield, SS1
Villegas, BJ1
Cutler, BS1
Gal, RA1
Gunasekera, J1
Massardo, T1
Shalev, Y1
Port, SC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study Examining the Value of Combined Exercise and Adenosine Stress Myocardial Perfusion Imaging as Compared With Adenosine Testing Alone for the Evaluation of Women at Intermediate or High Likelihood for Coronary Artery Disease[NCT00200629]Phase 4200 participants (Anticipated)Interventional2005-06-30Terminated (stopped due to Poor enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for dipyridamole and Death, Sudden, Cardiac

ArticleYear
[Anticoagulant, antiplatelet agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 4

    Topics: Anticoagulants; Aspirin; Death, Sudden, Cardiac; Dipyridamole; Drug Therapy, Combination; Heparin; H

2003
Cochrane review: dipyridamole for preventing major vascular events in patients with vascular disease.
    Stroke, 2003, Volume: 34, Issue:8

    Topics: Death, Sudden, Cardiac; Dipyridamole; Drug Therapy, Combination; Humans; Myocardial Infarction; Plat

2003
Coronary slow flow phenomenon and risk for sudden cardiac death due to ventricular arrhythmias: a case report and review of literature.
    Clinical cardiology, 2008, Volume: 31, Issue:8

    Topics: Administration, Oral; Coronary Circulation; Death, Sudden, Cardiac; Dipyridamole; Electrocardiograph

2008
[Cardiac sarcoidosis].
    Annales de medecine interne, 2001, Volume: 152, Issue:2

    Topics: Anti-Inflammatory Agents; Biopsy; Cardiomyopathies; Cardiomyopathy, Restrictive; Cardiovascular Agen

2001
Four patients with both thrombotic thrombocytopenic purpura and autoimmune thrombocytopenic purpura: the concept of a mixed immune thrombocytopenia syndrome and indications for plasma exchange.
    Journal of clinical apheresis, 2001, Volume: 16, Issue:4

    Topics: Adult; Arthritis, Rheumatoid; Aspirin; Autoimmune Diseases; Blood Platelets; Combined Modality Thera

2001

Trials

1 trial available for dipyridamole and Death, Sudden, Cardiac

ArticleYear
Safety of early intravenous dipyridamole technetium 99m sestamibi SPECT myocardial perfusion imaging after uncomplicated first myocardial infarction. Early Post MI IV Dipyridamole Study (EPIDS).
    American heart journal, 1997, Volume: 134, Issue:1

    Topics: Angina, Unstable; Blood Pressure; Coronary Circulation; Death, Sudden, Cardiac; Dipyridamole; Electr

1997

Other Studies

16 other studies available for dipyridamole and Death, Sudden, Cardiac

ArticleYear
Anomalous left main coronary artery origin, silent ischaemia, risk of sudden death: a triad detected by combining coronary CT and dipyridamole SPECT.
    BMJ case reports, 2013, Aug-05, Volume: 2013

    Topics: Aged; Coronary Vessel Anomalies; Death, Sudden, Cardiac; Dipyridamole; Humans; Ischemia; Male; Multi

2013
Blunted heart rate response as a predictor of cardiac death in patients undergoing vasodilator stress technetium-99m sestamibi gated SPECT myocardial perfusion imaging.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2010, Volume: 17, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Connecticut; Death, Sudden, Cardiac; Dipyridamole; Electrocardiography;

2010
The additive prognostic value of wall motion abnormalities and coronary flow reserve during dipyridamole stress echo.
    European heart journal, 2008, Volume: 29, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Coronary Artery Disease; Coronary Circulation; Dea

2008
Sex differences in perioperative and long-term cardiac event-free survival in vascular surgery patients. An analysis of clinical and scintigraphic variables.
    Circulation, 1995, Feb-15, Volume: 91, Issue:4

    Topics: Aged; Cohort Studies; Death, Sudden, Cardiac; Dipyridamole; Disease-Free Survival; Female; Heart; Hu

1995
Prognostic value of dipyridamole thallium scintigraphy in patients with coronary artery disease treated medically.
    Japanese circulation journal, 1993, Volume: 57, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiac Catheterization; Coronary Disease; Dea

1993
Extent of jeopardized viable myocardium determined by myocardial perfusion imaging best predicts perioperative cardiac events in patients undergoing noncardiac surgery.
    Journal of the American College of Cardiology, 1993, Volume: 21, Issue:2

    Topics: Aged; Angina, Unstable; Cohort Studies; Death, Sudden, Cardiac; Diabetes Mellitus; Dipyridamole; Fem

1993
Cardiac risk stratification using dipyridamole myocardial perfusion imaging and ambulatory ECG monitoring prior to vascular surgery.
    European journal of vascular surgery, 1993, Volume: 7, Issue:2

    Topics: Adult; Aged; Cause of Death; Coronary Circulation; Death, Sudden, Cardiac; Dipyridamole; Electrocard

1993
Dipyridamole technetium 99m sestamibi myocardial tomography for preoperative cardiac risk stratification before major or minor nonvascular surgery.
    American heart journal, 1996, Volume: 132, Issue:3

    Topics: Aged; Angina, Unstable; Coronary Circulation; Coronary Disease; Death, Sudden, Cardiac; Dipyridamole

1996
Cardiac complications in noncardiac surgery: relative value of resting two-dimensional echocardiography and dipyridamole thallium imaging.
    American heart journal, 1996, Volume: 132, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiac Output, Low; Coronary Artery Bypass; Coronary Disease;

1996
Cardiac assessment prior to vascular surgery: is dipyridamole-sestamibi necessary?
    Annals of vascular surgery, 1996, Volume: 10, Issue:4

    Topics: Age Factors; Aged; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Coronary Arter

1996
Prognostic importance of scintigraphic left ventricular cavity dilation during intravenous dipyridamole technetium-99m sestamibi myocardial tomographic imaging in predicting coronary events.
    The American journal of cardiology, 1997, Mar-01, Volume: 79, Issue:5

    Topics: Aged; Cardiac Output, Low; Coronary Circulation; Coronary Disease; Coronary Vessels; Death, Sudden,

1997
Relation of gender to physician use of test results and to the prognostic value of stress technetium 99m sestamibi myocardial single-photon emission computed tomography scintigraphy.
    American heart journal, 1997, Volume: 134, Issue:1

    Topics: Angina Pectoris; Angina, Unstable; Cardiac Catheterization; Coronary Disease; Death, Sudden, Cardiac

1997
Prognostic value of dipyridamole thallium imaging after acute myocardial infarction in older patients.
    Journal of the American Geriatrics Society, 1999, Volume: 47, Issue:3

    Topics: Aged; Death, Sudden, Cardiac; Dipyridamole; Exercise Test; Female; Humans; Infusions, Intravenous; M

1999
Prediction of cardiovascular events in clinically selected high-risk NIDDM patients. Prognostic value of exercise stress test and thallium-201 single-photon emission computed tomography.
    Diabetes care, 1999, Volume: 22, Issue:1

    Topics: Activities of Daily Living; Aged; Analysis of Variance; Cardiovascular Diseases; Cholesterol; Choles

1999
Prediction of late cardiac events by dipyridamole thallium imaging in patients undergoing elective vascular surgery.
    The American journal of cardiology, 1992, Nov-15, Volume: 70, Issue:15

    Topics: Aged; Death, Sudden, Cardiac; Dipyridamole; Female; Humans; Male; Myocardial Infarction; Postoperati

1992
Long-term prognostic value of a normal dipyridamole thallium-201 perfusion scan.
    Clinical cardiology, 1991, Volume: 14, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Cause of Death; Coronary Disease; Death, Sudden, Ca

1991