dipyridamole has been researched along with Cerebral Amyloid Angiopathy in 1 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Cerebral Amyloid Angiopathy: A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia (BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalized AMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE. (from Kumar: Robbins and Cotran: Pathologic Basis of Disease, 7th ed., 2005)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dipyridamole treatment did not worsen frequency and size of cerebral microscopic bleeding." | 1.37 | Therapeutic modulation of cerebral microhemorrhage in a mouse model of cerebral amyloid angiopathy. ( Cribbs, DH; Fisher, M; Passos, GF; Quiring, D; Vasilevko, V; Ventura, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisher, M | 1 |
| Vasilevko, V | 1 |
| Passos, GF | 1 |
| Ventura, C | 1 |
| Quiring, D | 1 |
| Cribbs, DH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-invasive Evaluation of Cerebrovascular Reactivity in Spontaneous Intracerebral Hemorrhage[NCT03815513] | Phase 1 | 60 participants (Anticipated) | Interventional | 2019-01-21 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for dipyridamole and Cerebral Amyloid Angiopathy
| Article | Year |
|---|---|
Therapeutic modulation of cerebral microhemorrhage in a mouse model of cerebral amyloid angiopathy.
Topics: Animals; Cerebral Amyloid Angiopathy; Cerebral Hemorrhage; Dipyridamole; Disease Models, Animal; Fem | 2011 |