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dipyridamole and Cell Transformation, Neoplastic

dipyridamole has been researched along with Cell Transformation, Neoplastic in 5 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
" In the present study, however, changes in intracellular cyclic AMP level in several lines of cultured cells (normal 3T3 and SV40 and polyomavirus-transformed 3T3 cells; 3T6, C6 GLIOMA, MOUSE L, and Novikoff rat hepatoma cells) by treatment with papaverine, prostaglandine E1 or isoproterenol did not correlate with the inhibition of the uridine, hypoxanthine or deoxyglucose transport rates by these chemicals."3.65Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells. ( Plagemann, PG; Sheppard, JR, 1975)
"More than 85% breast cancers are sporadic and attributable to long-term exposure to environmental carcinogens through a multistep and multiyear disease process."1.40Dipyridamole intervention of breast cell carcinogenesis. ( Choudhary, S; Sood, S; Wang, HC, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choudhary, S1
Sood, S1
Wang, HC1
Sheppard, JR1
Plagemann, PG4
Renner, ED1
Bernlohr, RW1
Richey, DP1

Reviews

1 review available for dipyridamole and Cell Transformation, Neoplastic

ArticleYear
Transport of nucleosides, nucleic acid bases, choline and glucose by animal cells in culture.
    Biochimica et biophysica acta, 1974, Dec-16, Volume: 344, Issue:3-4

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cell Membrane; Cell Transfo

1974

Other Studies

4 other studies available for dipyridamole and Cell Transformation, Neoplastic

ArticleYear
Dipyridamole intervention of breast cell carcinogenesis.
    Molecular carcinogenesis, 2014, Volume: 53, Issue:3

    Topics: Apoptosis; Benzo(a)pyrene; Blotting, Western; Breast; Breast Neoplasms; Carcinogens; Cell Adhesion;

2014
Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells.
    Journal of cellular physiology, 1975, Volume: 85, Issue:2 Pt 1

    Topics: Animals; Biological Transport, Active; Bucladesine; Carcinoma, Hepatocellular; Cell Division; Cell L

1975
Permeation of glucose by simple and facilitated diffusion by Novikoff rat hepatoma cells in suspension culture and its relationship to glucose metabolism.
    The Journal of biological chemistry, 1972, Sep-25, Volume: 247, Issue:18

    Topics: Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Frac

1972
Deoxyglucose transport of uninfected, murine sarcoma virus-transformed, and murine leukemia virus-infected mouse cells.
    Journal of cellular physiology, 1973, Volume: 82, Issue:3

    Topics: Animals; Biological Transport, Active; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured;

1973