dipyridamole has been researched along with Carotid Artery Narrowing in 11 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Data from one randomised controlled trial showed no significant difference in benefit with aspirin versus placebo in asymptomatic carotid stenosis, but it is still reasonable to recommend aspirin (81-325 mg daily) for prevention of vascular events in these patients." | 5.01 | Optimal Antiplatelet Therapy in Moderate to Severe Asymptomatic and Symptomatic Carotid Stenosis: A Comprehensive Review of the Literature. ( de Borst, GJ; Halliday, A; Hamilton, G; Kakkos, S; McCabe, DJH; Murphy, SJX; Naylor, AR; Ricco, JB; Sillesen, H; Vega de Ceniga, M, 2019) |
| "Drugs that prevent platelets from sticking together-ie, aspirin, dipyridamole, and clopidogrel-are an important part of therapy to prevent recurrence of ischemic stroke of atherosclerotic origin." | 4.89 | Antiplatelet therapy to prevent recurrent stroke: Three good options. ( Mansoor, AH; Mujtaba, MT; Silver, B, 2013) |
| " Currently, aspirin is generally prescribed for the primary prevention of stroke despite a number of trial results on effectiveness proving inconclusive." | 4.85 | Antithrombotic therapies in cerebrovascular disease: what should we use as secondary prevention in patients with carotid artery disease? ( Beckman, JA, 2009) |
| "Dipyridamole (0." | 1.29 | Brain SPECT with dipyridamole stress to evaluate cerebral blood flow reserve in carotid artery disease. ( Brannon, WL; Farrell, JJ; Hwang, TL; Saenz, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lana, D | 1 |
| Ugolini, F | 1 |
| Melani, A | 1 |
| Nosi, D | 1 |
| Pedata, F | 1 |
| Giovannini, MG | 1 |
| Murphy, SJX | 1 |
| Naylor, AR | 1 |
| Ricco, JB | 1 |
| Sillesen, H | 1 |
| Kakkos, S | 1 |
| Halliday, A | 1 |
| de Borst, GJ | 1 |
| Vega de Ceniga, M | 1 |
| Hamilton, G | 1 |
| McCabe, DJH | 1 |
| Mansoor, AH | 1 |
| Mujtaba, MT | 1 |
| Silver, B | 1 |
| Beckman, JA | 1 |
| Kramer, J | 1 |
| Abraham, J | 1 |
| Teven, CM | 1 |
| Jones, PA | 1 |
| Ombrellaro, MP | 1 |
| Dieter, RA | 1 |
| Freeman, M | 1 |
| Stevens, SL | 1 |
| Goldman, MH | 1 |
| Cousineau, DF | 1 |
| Goresky, CA | 1 |
| Rose, CP | 1 |
| Simard, A | 1 |
| Schwab, AJ | 1 |
| Hwang, TL | 1 |
| Saenz, A | 1 |
| Farrell, JJ | 1 |
| Brannon, WL | 1 |
| Klijn, CJ | 1 |
| van Buren, PA | 1 |
| Kappelle, LJ | 1 |
| Tulleken, CA | 1 |
| Eikelboom, BC | 1 |
| Algra, A | 1 |
| van Gijn, J | 1 |
| Diener, HC | 1 |
| Harker, LA | 1 |
| Bernstein, EF | 1 |
| Dilley, RB | 1 |
| Scala, TE | 1 |
| Sise, MJ | 1 |
| Hye, RJ | 1 |
| Otis, SM | 1 |
| Roberts, RS | 1 |
| Gent, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000527] | Phase 2 | 0 participants | Interventional | 1986-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for dipyridamole and Carotid Artery Narrowing
| Article | Year |
|---|---|
Optimal Antiplatelet Therapy in Moderate to Severe Asymptomatic and Symptomatic Carotid Stenosis: A Comprehensive Review of the Literature.
Topics: Aspirin; Asymptomatic Diseases; Carotid Stenosis; Clopidogrel; Dipyridamole; Drug Therapy, Combinati | 2019 |
Antiplatelet therapy to prevent recurrent stroke: Three good options.
Topics: Aspirin; Carotid Stenosis; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Secon | 2013 |
Antithrombotic therapies in cerebrovascular disease: what should we use as secondary prevention in patients with carotid artery disease?
Topics: Anticoagulants; Aspirin; Brain Ischemia; Carotid Stenosis; Clopidogrel; Dipyridamole; Drug Therapy, | 2009 |
Stroke prevention: antiplatelet and antithrombolytic therapy.
Topics: Anticoagulants; Aspirin; Brain Damage, Chronic; Carotid Stenosis; Clinical Trials as Topic; Clopidog | 2000 |
1 trial available for dipyridamole and Carotid Artery Narrowing
| Article | Year |
|---|---|
Failure of aspirin plus dipyridamole to prevent restenosis after carotid endarterectomy.
Topics: Aged; Aspirin; Carotid Stenosis; Combined Modality Therapy; Dipyridamole; Drug Therapy, Combination; | 1992 |
6 other studies available for dipyridamole and Carotid Artery Narrowing
| Article | Year |
|---|---|
The neuron-astrocyte-microglia triad in CA3 after chronic cerebral hypoperfusion in the rat: Protective effect of dipyridamole.
Topics: Analysis of Variance; Animals; Apoptosis; Astrocytes; Brain Ischemia; CA3 Region, Hippocampal; Carot | 2017 |
Role of antiplatelets in carotid artery stenting.
Topics: Angioplasty, Balloon; Aspirin; Carotid Stenosis; Clinical Trials as Topic; Clopidogrel; Dipyridamole | 2007 |
Role of dipyridamole myocardial scintigraphy in carotid artery surgery.
Topics: Aged; Carotid Stenosis; Dipyridamole; Endarterectomy, Carotid; Evaluation Studies as Topic; Female; | 1995 |
Effects of flow, perfusion pressure, and oxygen consumption on cardiac capillary exchange.
Topics: Animals; Blood Flow Velocity; Blood Gas Analysis; Capillary Permeability; Carotid Stenosis; Coronary | 1995 |
Brain SPECT with dipyridamole stress to evaluate cerebral blood flow reserve in carotid artery disease.
Topics: Acetazolamide; Aged; Brain; Brain Ischemia; Carotid Artery, Internal; Carotid Stenosis; Cerebral Inf | 1996 |
Outcome in patients with symptomatic occlusion of the internal carotid artery.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Carotid Artery, Internal; Carotid Stenosis; | 2000 |