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dipyridamole and Cardiomyopathy, Hypertrophic Obstructive

dipyridamole has been researched along with Cardiomyopathy, Hypertrophic Obstructive in 40 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"1), with left ventricular hypertrophy, typical angina pectoris, ischemia that can be induced by exercise-electrocardiography test, without previous myocardial infarction, myocardial revascularization or diabetes mellitus, underwent dipyridamole-echocardiography test, thallium exercise myocardial scintigraphy and coronarography."9.08[Dipyridamole-echocardiography and thallium exercise myocardial scintigraphy in the diagnosis of obstructive coronary or microvascular disease in hypertensive patients with left ventricular hypertrophy and angina]. ( Astarita, C; Gambardella, S; Liguori, E; Maresca, FS; Nicolai, E; Rumolo, S, 1998)
"1), with left ventricular hypertrophy, typical angina pectoris, ischemia that can be induced by exercise-electrocardiography test, without previous myocardial infarction, myocardial revascularization or diabetes mellitus, underwent dipyridamole-echocardiography test, thallium exercise myocardial scintigraphy and coronarography."5.08[Dipyridamole-echocardiography and thallium exercise myocardial scintigraphy in the diagnosis of obstructive coronary or microvascular disease in hypertensive patients with left ventricular hypertrophy and angina]. ( Astarita, C; Gambardella, S; Liguori, E; Maresca, FS; Nicolai, E; Rumolo, S, 1998)
"Maximal wall thickness was identified as the strongest predictor of impaired dipyridamole-induced hyperemia and flow reserve in our study, whereas outflow tract obstruction was not an independent determinant."3.78PET/CT assessment of symptomatic individuals with obstructive and nonobstructive hypertrophic cardiomyopathy. ( Abraham, MR; Abraham, TP; Bengel, FM; Bravo, PE; Higuchi, T; Merrill, J; Pinheiro, A; Rischpler, C; Santaularia-Tomas, M; Wahl, RL, 2012)
"In 34 patients with HCM, PET was performed using (13)N-labeled ammonia during hyperemia induced by intravenous dipyridamole."3.74Spatial relationship between coronary microvascular dysfunction and delayed contrast enhancement in patients with hypertrophic cardiomyopathy. ( Betti, I; Camici, PG; Casolo, G; Cecchi, F; Olivotto, I; Pupi, A; Rega, L; Sciagrà, R; Sotgia, B, 2008)
"Twenty-nine patients (37%) showed ECG (ie, ST depression > or = 2 mV) signs of myocardial ischemia during dipyridamole test (group 1), whereas 50 (63%) had a negative test (group 2)."3.69Dipyridamole-induced ischemia as a prognostic marker of future adverse cardiac events in adult patients with hypertrophic cardiomyopathy. Echo Persantine Italian Cooperative (EPIC) Study Group, Subproject Hypertrophic Cardiomyopathy. ( Barilli, A; Ceriati, R; Iori, E; Lazzeroni, E; Maurizio, AR; Morozzi, L; Palma, G; Picano, E, 1997)
"Dipyridamole MBF was 1."2.69Transmural myocardial blood flow distribution in hypertrophic cardiomyopathy and effect of treatment. ( Boyd, H; Camici, PG; Choudhury, L; Elliott, P; Lammertsma, AA; McKenna, WJ; Rimoldi, O; Ryan, M, 1999)
"Verapamil has been shown to ameliorate silent myocardial perfusion defects documented by thallium-201 in patients with HC."2.67Effect of verapamil on absolute myocardial blood flow in hypertrophic cardiomyopathy. ( Camici, PG; Cecchi, F; Choudhury, L; Gistri, R; Montereggi, A; Salvadori, PA; Sorace, O, 1994)
"For the secondary left ventricular hypertrophy patient group, baseline myocardial blood flow was 1."1.30Coronary vasodilator reserve in primary and secondary left ventricular hypertrophy. A study with positron emission tomography. ( Camici, PG; Choudhury, L; Nihoyannopoulos, P; Patel, D; Rosen, SD, 1997)
"Fourteen patients with chronic renal failure (CRF) were studied by dipyridamole 201Tl myocardial scintigraphy."1.29[Study of washout rate in patients with chronic renal failure by dipyridamole 201Tl myocardial scintigraphy--comparison with hypertrophic cardiomyopathy]. ( Ito, T; Matsumura, K; Mizutani, Y; Nakagawa, T; Senda, Y; Takagi, I; Yasuda, R; Yoshida, N, 1993)
"Dipyridamole-assessed CFR, was weakly related to parameters of exercise capacity."1.29Coronary flow reserve and exercise capacity in hypertrophic cardiomyopathy. ( Bodzoń, W; Dimitrow, PP; Dubiel, JS; Krzanowski, M; Szczeklik, A, 1996)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19909 (22.50)18.7374
1990's21 (52.50)18.2507
2000's7 (17.50)29.6817
2010's3 (7.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castagnoli, H1
Ferrantini, C1
Coppini, R1
Passeri, A1
Baldini, K1
Berti, V1
Cecchi, F4
Olivotto, I3
Sciagrà, R2
Sotgia, B1
Casolo, G1
Rega, L1
Betti, I1
Pupi, A1
Camici, PG6
Cortigiani, L1
Rigo, F1
Gherardi, S1
Galderisi, M1
Sicari, R1
Picano, E5
Bravo, PE2
Pinheiro, A2
Higuchi, T1
Rischpler, C1
Merrill, J2
Santaularia-Tomas, M1
Abraham, MR2
Wahl, RL2
Abraham, TP2
Bengel, FM2
Pozios, I1
Tsui, BM1
Cannon, RO2
Gistri, R5
Lorenzoni, R3
Chiriatti, G4
Lazzeroni, E2
Dodi, C1
Morozzi, L2
Chiriatti, GP1
Lu, C1
Botti, G1
Choudhury, L3
Montereggi, A1
Sorace, O1
Salvadori, PA2
Pedrinelli, R1
Spessot, M1
Salvadori, P2
Catapano, G1
Panarace, G1
Papi, L3
L'Abbate, A3
Matsumura, K1
Senda, Y1
Ito, T1
Mizutani, Y1
Yoshida, N1
Yasuda, R1
Takagi, I1
Nakagawa, T1
Takata, J1
Counihan, PJ1
Gane, JN2
Doi, Y3
Chikamori, T1
Ozawa, T2
McKenna, WJ4
Taki, J1
Nakajima, K1
Bunko, H1
Shimizu, M1
Taniguchi, M1
Hisada, K1
Motz, W1
Strauer, BE1
Elliott, PM2
Rosano, GM1
Gill, JS1
Poole-Wilson, PA1
Kaski, JC2
Dimitrow, PP1
Krzanowski, M1
Bodzoń, W1
Szczeklik, A1
Dubiel, JS1
Rosen, SD1
Patel, D1
Nihoyannopoulos, P1
Maurizio, AR1
Palma, G1
Ceriati, R1
Iori, E1
Barilli, A1
Yamada, M2
Prasad, K1
Lowe, CM1
Kalsi, KK1
Smolenski, RT1
Pritchard, RD1
Khaghani, A1
Seymour, AM1
Yacoub, MH1
Astarita, C1
Nicolai, E1
Liguori, E1
Gambardella, S1
Rumolo, S1
Maresca, FS1
Elliott, P1
Rimoldi, O1
Ryan, M1
Lammertsma, AA1
Boyd, H1
Kawada, N1
Sakuma, H1
Yamakado, T1
Takeda, K1
Isaka, N1
Nakano, T1
Higgins, CB1
Tadamura, E1
Yoshibayashi, M1
Yonemura, T1
Kudoh, T1
Kubo, S1
Motooka, M1
Nohara, R1
Matsumori, A1
Sasayama, S1
Matsuda, T1
Tamaki, N1
Konishi, J1
Pingitore, A1
Paterni, M1
Passera, M1
Paeng, JC1
Lee, DS1
Yeo, JS1
Noh, CI1
Kim, YK1
Chung, JK1
Lee, MC1
Koga, Y2
Kihara, K3
Yamaguchi, R3
Wada, T1
Toshima, H3
Bellina, RC2
Di Marco, S1
Nista, N2
Riva, A1
Camici, P1
Italiani, G1
Parodi, O1
Ogata, M1
Yabe, T1
Yonesawa, Y1
Takada, J1
Odawara, H1
Lucarini, AR1
Lattanzi, F1
De Prisco, F1
Distante, A1
Salvetti, A1
Mori, T2
Yamabe, H1
Yokota, Y2
Fukuzaki, H2
Himi, T1
Endo, M1
Kagaya, A1
Yoshida, K1
Masuda, Y1
Inagaki, Y1
Fukuda, H1
Fukuda, N1
Iinuma, T1
Yamazaki, T1
Suda, K1
Ohnishi, M1
Kanoh, Y1
Shiotani, H1
Fujitani, K1
Maeda, K1
Shimamatsu, M1
Pirelli, S1
Inglese, E1
Suppa, M1
Corrada, E1
Piccalò, G1
Campolo, L1
Carù, B1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The International Stress Echo Study to to Define the Future of Imaging[NCT05081115]10,000 participants (Anticipated)Observational [Patient Registry]2021-04-01Recruiting
H215O Positron Emission Tomography (PET) in the Assessment of Synovial Blood Flow in Rheumatoid Arthritis Patients[NCT00014794]Phase 110 participants Interventional2001-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dipyridamole and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
Coronary flow reserve in patients with chest pain, angiographically normal coronary arteries and normal left ventricle, dilated cardiomyopathy, and hypertrophic cardiomyopathy.
    Bibliotheca cardiologica, 1989, Issue:44

    Topics: Angina Pectoris; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Coronary Angiography; Corona

1989

Trials

4 trials available for dipyridamole and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
Effect of verapamil on absolute myocardial blood flow in hypertrophic cardiomyopathy.
    The American journal of cardiology, 1994, Aug-15, Volume: 74, Issue:4

    Topics: Adult; Ammonia; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Double-Blind Metho

1994
Improvement of coronary flow reserve after long-term therapy with enalapril.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:5

    Topics: Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiomyopathy, Hyp

1996
[Dipyridamole-echocardiography and thallium exercise myocardial scintigraphy in the diagnosis of obstructive coronary or microvascular disease in hypertensive patients with left ventricular hypertrophy and angina].
    Giornale italiano di cardiologia, 1998, Volume: 28, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Cardiomyopathy, Hypertrophic; Coronary Disease; Dipyridamole; Echocard

1998
Transmural myocardial blood flow distribution in hypertrophic cardiomyopathy and effect of treatment.
    Basic research in cardiology, 1999, Volume: 94, Issue:1

    Topics: Adult; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Vessels; Dipyridamole; Femal

1999

Other Studies

35 other studies available for dipyridamole and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
Role of quantitative myocardial positron emission tomography for risk stratification in patients with hypertrophic cardiomyopathy: a 2016 reappraisal.
    European journal of nuclear medicine and molecular imaging, 2016, Volume: 43, Issue:13

    Topics: Adult; Cardiomyopathy, Hypertrophic; Causality; Comorbidity; Coronary Artery Disease; Dipyridamole;

2016
Spatial relationship between coronary microvascular dysfunction and delayed contrast enhancement in patients with hypertrophic cardiomyopathy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:7

    Topics: Adolescent; Adult; Aged; Ammonia; Cardiomyopathy, Hypertrophic; Contrast Media; Coronary Circulation

2008
Prognostic implications of coronary flow reserve on left anterior descending coronary artery in hypertrophic cardiomyopathy.
    The American journal of cardiology, 2008, Dec-15, Volume: 102, Issue:12

    Topics: Cardiomyopathy, Hypertrophic; Coronary Circulation; Coronary Vessels; Dipyridamole; Echocardiography

2008
PET/CT assessment of symptomatic individuals with obstructive and nonobstructive hypertrophic cardiomyopathy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:3

    Topics: Adult; Aged; Algorithms; Cardiomyopathy, Hypertrophic; Coronary Circulation; Data Interpretation, St

2012
Comparison and effectiveness of regadenoson versus dipyridamole on stress electrocardiographic changes during positron emission tomography evaluation of patients with hypertrophic cardiomyopathy.
    The American journal of cardiology, 2012, Oct-01, Volume: 110, Issue:7

    Topics: Adenosine A2 Receptor Antagonists; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole;

2012
Assessing risk in hypertrophic cardiomyopathy.
    The New England journal of medicine, 2003, Sep-11, Volume: 349, Issue:11

    Topics: Animals; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Humans; Prognosis; Risk F

2003
Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy.
    The New England journal of medicine, 2003, Sep-11, Volume: 349, Issue:11

    Topics: Adult; Analysis of Variance; Cardiomyopathy, Hypertrophic; Cohort Studies; Coronary Circulation; Dip

2003
Dipyridamole echocardiography for diagnosis of coexistent coronary artery disease in hypertrophic cardiomyopathy. Echo-Persantine International Cooperative (EPIC) Study Group--Subproject Hypertrophic Cardiomyopathy.
    The American journal of cardiology, 1995, Apr-15, Volume: 75, Issue:12

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Coronary Angiograp

1995
Evidence for a systemic defect of resistance-sized arterioles in hypertrophic cardiomyopathy.
    Coronary artery disease, 1993, Volume: 4, Issue:1

    Topics: Adult; Aged; Cardiac Volume; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Echoc

1993
[Study of washout rate in patients with chronic renal failure by dipyridamole 201Tl myocardial scintigraphy--comparison with hypertrophic cardiomyopathy].
    Kaku igaku. The Japanese journal of nuclear medicine, 1993, Volume: 30, Issue:11

    Topics: Cardiomyopathy, Hypertrophic; Coronary Disease; Dipyridamole; Female; Heart; Humans; Kidney Failure,

1993
Regional thallium-201 washout and myocardial hypertrophy in hypertrophic cardiomyopathy and its relation to exertional chest pain.
    The American journal of cardiology, 1993, Jul-15, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Aged; Cardiomegaly; Cardiomyopathy, Hypertrophic; Chest Pain; Chi-Square Distribu

1993
123I-labelled BMIPP fatty acid myocardial scintigraphy in patients with hypertropic cardiomyopathy: SPECT comparison with stress 201Tl.
    Nuclear medicine communications, 1993, Volume: 14, Issue:3

    Topics: Adult; Aged; Cardiomyopathy, Hypertrophic; Dipyridamole; Fatty Acids; Female; Heart; Humans; Iodine

1993
Changes in coronary sinus pH during dipyridamole stress in patients with hypertrophic cardiomyopathy.
    Heart (British Cardiac Society), 1996, Volume: 75, Issue:2

    Topics: Adult; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Electrocardiography; Female

1996
Coronary flow reserve and exercise capacity in hypertrophic cardiomyopathy.
    Heart and vessels, 1996, Volume: 11, Issue:3

    Topics: Adult; Blood Flow Velocity; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Echoca

1996
Coronary vasodilator reserve in primary and secondary left ventricular hypertrophy. A study with positron emission tomography.
    European heart journal, 1997, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Fe

1997
Dipyridamole-induced ischemia as a prognostic marker of future adverse cardiac events in adult patients with hypertrophic cardiomyopathy. Echo Persantine Italian Cooperative (EPIC) Study Group, Subproject Hypertrophic Cardiomyopathy.
    Circulation, 1997, Dec-16, Volume: 96, Issue:12

    Topics: Adult; Aged; Cardiomyopathy, Hypertrophic; Dipyridamole; Echocardiography; Electrocardiography; Fema

1997
Dipyridamole stress thallium-201 perfusion abnormalities in patients with hypertrophic cardiomyopathy. Relationship to clinical presentation and outcome.
    European heart journal, 1998, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiomyopathy, Hypertrophic; Child; Dipyridamole; Human

1998
Effects of dipyridamole and adenine/ribose on ATP concentration and adenosine production in cardiac myocytes.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Cardiomyopathy, Dilated; Cardiomyop

1998
Hypertrophic cardiomyopathy: MR measurement of coronary blood flow and vasodilator flow reserve in patients and healthy subjects.
    Radiology, 1999, Volume: 211, Issue:1

    Topics: Blood Flow Velocity; Cardiomyopathy, Hypertrophic; Case-Control Studies; Coronary Circulation; Dipyr

1999
Significant regional heterogeneity of coronary flow reserve in paediatric hypertrophic cardiomyopathy.
    European journal of nuclear medicine, 2000, Volume: 27, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Cardiomyopathy, Hypertrophic; Child; Corona

2000
Stress-induced changes in subendocardial tissue texture in hypertrophic cardiomyopathy: an echocardiographic videodensitometric study.
    The international journal of cardiovascular imaging, 2001, Volume: 17, Issue:4

    Topics: Adult; Cardiomyopathy, Hypertrophic; Densitometry; Dipyridamole; Echocardiography, Stress; Endocardi

2001
Septal stunning by dipyridamole stress shown on quantitative gated perfusion SPECT in a child with hypertrophic cardiomyopathy.
    Clinical nuclear medicine, 2002, Volume: 27, Issue:2

    Topics: Cardiomyopathy, Hypertrophic; Child; Dipyridamole; Gated Blood-Pool Imaging; Heart Septum; Humans; M

2002
Therapeutic effect of oral dipyridamole on myocardial perfusion and cardiac performance in patients with hypertrophic cardiomyopathy.
    American heart journal, 1992, Volume: 123, Issue:2

    Topics: Administration, Oral; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Exercise Tes

1992
[Regional myocardial perfusion and ischemia in hypertrophic cardiomyopathy].
    Giornale italiano di cardiologia, 1991, Volume: 21, Issue:7

    Topics: Adult; Aged; Ammonia; Cardiomyopathy, Hypertrophic; Coronary Circulation; Coronary Disease; Dipyrida

1991
Coronary vasodilation is impaired in both hypertrophied and nonhypertrophied myocardium of patients with hypertrophic cardiomyopathy: a study with nitrogen-13 ammonia and positron emission tomography.
    Journal of the American College of Cardiology, 1991, Mar-15, Volume: 17, Issue:4

    Topics: Ammonia; Cardiomyopathy, Hypertrophic; Coronary Circulation; Coronary Vessels; Dipyridamole; Female;

1991
Decreased coronary vasodilatory capacity in hypertrophic cardiomyopathy determined by split-dose thallium-dipyridamole myocardial scintigraphy.
    The American journal of cardiology, 1990, May-01, Volume: 65, Issue:16

    Topics: Adolescent; Adult; Aged; Cardiomyopathy, Hypertrophic; Coronary Angiography; Coronary Vessels; Dipyr

1990
[Therapeutic effects of oral dipyridamole on myocardial perfusion and left ventricular function in patients with hypertrophic cardiomyopathy].
    Kaku igaku. The Japanese journal of nuclear medicine, 1990, Volume: 27, Issue:2

    Topics: Administration, Oral; Adult; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Exerc

1990
[Assessment of prognosis of patients with ventricular tachycardia: role of the underlying heart disease].
    Journal of cardiology. Supplement, 1989, Volume: 22

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Catheterization; Cardiomyopathy, Dilated; Cardio

1989
Dipyridamole-echocardiography test in essential hypertensives with chest pain and angiographically normal coronary arteries.
    American journal of hypertension, 1989, Volume: 2, Issue:2 Pt 1

    Topics: Angina Pectoris; Cardiomyopathy, Hypertrophic; Coronary Angiography; Coronary Disease; Dipyridamole;

1989
Clinical significance of dipyridamole Tl-201 emission computed tomography perfusion abnormality for evaluating pathophysiological and pathological aspects in hypertrophic cardiomyopathy.
    Japanese circulation journal, 1988, Volume: 52, Issue:2

    Topics: Adult; Aged; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Echocardiography; Fem

1988
[Usefulness of positron emission tomography in the assessment of the effect of dipyridamole on regional myocardial blood flow].
    Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:5

    Topics: Ammonia; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Humans; Myocardial Infarc

1988
[Hypertrophic non-obstructive cardiomyopathy assessed by dipyridamole thallium single photon emission computed tomography: comparisons with hypertrophic cardiomyopathy with a dilated heart].
    Journal of cardiology, 1987, Volume: 17, Issue:1

    Topics: Adult; Aged; Cardiac Catheterization; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Dipyrid

1987
[Decreased coronary reserve in patients with hypertrophic cardiomyopathy--a study using split dose thallium-201 dipyridamole myocardial imaging].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Female; Heart;

1987
Impaired coronary vasodilatory capacity after dipyridamole administration in hypertrophic cardiomyopathy.
    Japanese heart journal, 1987, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Coronary Circulation; Coro

1987
[Assessment of coronary stenosis by myocardial scintigraphy with thallium-201 after dipyridamol infusion].
    Giornale italiano di cardiologia, 1985, Volume: 15, Issue:5

    Topics: Adult; Aged; Angina Pectoris; Cardiomyopathy, Hypertrophic; Dipyridamole; Female; Heart; Humans; Mal

1985