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dipyridamole and Cardiomegaly

dipyridamole has been researched along with Cardiomegaly in 30 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"In a population of patients with chronic renal failure (CRF) and a high prevalence of left ventricular hypertrophy (LVH) undergoing chronic hemodialysis, we investigated the association between the results of dipyridamole-thallium tests (DTTs) and the occurrence of ventricular arrhythmias."7.68Dipyridamole-thallium tests are predictive of severe cardiac arrhythmias in patients with left ventricular hypertrophy. ( Barbieri, A; Canziani, ME; Cassiolato, JL; Castiglioni, ML; Draibe, SA; Gil, MA; Lima, VC; Martinez, EE; Saragoça, MA, 1991)
"Furthermore."5.30Valsartan and coronary haemodynamics in early post-myocardial infarction in rats. ( De Gasparo, M; Fornes, P; Gervais, M; Giudicelli, JF; Richer, C, 1999)
"In a population of patients with chronic renal failure (CRF) and a high prevalence of left ventricular hypertrophy (LVH) undergoing chronic hemodialysis, we investigated the association between the results of dipyridamole-thallium tests (DTTs) and the occurrence of ventricular arrhythmias."3.68Dipyridamole-thallium tests are predictive of severe cardiac arrhythmias in patients with left ventricular hypertrophy. ( Barbieri, A; Canziani, ME; Cassiolato, JL; Castiglioni, ML; Draibe, SA; Gil, MA; Lima, VC; Martinez, EE; Saragoça, MA, 1991)
" The transient dyssynergy detected by two-dimensional echocardiography and evoked during dipyridamole infusion is a marker of coronary disease that is equally reliable in normotensive and hypertensive individuals."3.68Dipyridamole echocardiography stress testing in hypertensive patients. Targets and tools. ( Camici, P; L'Abbate, A; Lattanzi, F; Lucarini, AR; Marini, C; Picano, E; Salvetti, A, 1991)
"Furthermore."1.30Valsartan and coronary haemodynamics in early post-myocardial infarction in rats. ( De Gasparo, M; Fornes, P; Gervais, M; Giudicelli, JF; Richer, C, 1999)
"Cardiac hypertrophy is associated with a decrease in coronary reserve."1.26Effects of duration and severity of arterial hypertension and cardiac hypertrophy on coronary vasodilator reserve. ( Marcus, ML; Peters, KG; Tomanek, RJ; Wangler, RD, 1982)
"In dogs with experimental cardiac hypertrophy in resting conditions, coronary blood flow and myocardial O2 consumption increased proportionately to the cardiac mass; coronary flow and O2 consumption per gram of myocardium, therefore, ranged within normal values."1.26Coronary blood flow and myocardial O2 consumption in hypertrophied cardiac muscle in dogs. ( Marchetti, GV; Merlo, L; Visioli, O, 1976)
"The dipyridamole treatment had no effect on the increase in systolic pressure, the contractility index of the aorta-stenosed animals and heart rate."1.25[Variation of mechanical and biochemical parameters of pressure-loaded rabbit hearts following chronic administration of dipyridamole]. ( Förster, W; Ritter, C; Weiss, M, 1975)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199019 (63.33)18.7374
1990's11 (36.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ESPLUGUES, J1
BRUGGER, A1
HUESO, E1
SOTO, L1
Wangler, RD2
Peters, KG2
Marcus, ML2
Tomanek, RJ3
Thormann, J1
Marchant, E1
Pichard, A1
Casanegra, P1
Rodríguez, JA1
Chamorro, G1
Corbalán, R1
DePace, NL1
Burke, W1
Kotler, MN1
Glazier, EE1
Takata, J1
Counihan, PJ1
Gane, JN1
Doi, Y1
Chikamori, T1
Ozawa, T1
McKenna, WJ1
Kozàkovà, M1
Palombo, C1
Pratali, L1
Pittella, G1
Galetta, F1
L'Abbate, A2
Gervais, M1
Richer, C1
Fornes, P1
De Gasparo, M1
Giudicelli, JF1
Strauer, BE1
Ritter, C2
Förster, W4
Blass, KE2
Triebe, G2
Traub, F1
Weiss, M1
Marchetti, GV1
Merlo, L1
Visioli, O1
Degenring, FH1
Curnish, RR1
Rubio, R1
Berne, RM1
Kupper, W1
Bleifeld, W1
Hanrath, P1
Hamm, C1
Mathey, D1
Waag, KL1
Mittmann, U1
Keller, HE1
Schäfer, H1
Schwierczenski, A1
Torry, RJ1
O'Brien, DM1
Connell, PM1
Prisant, LM2
von Dohlen, TW2
Houghton, JL2
Carr, AA2
Frank, MJ2
Saragoça, MA1
Canziani, ME1
Gil, MA1
Castiglioni, ML1
Cassiolato, JL1
Barbieri, A1
Lima, VC1
Draibe, SA1
Martinez, EE1
Lucarini, AR1
Picano, E1
Lattanzi, F1
Camici, P1
Marini, C1
Salvetti, A1
Marwick, TH1
Cook, SA1
Lafont, A1
Underwood, DA1
Salcedo, EE1
Goldstein, RA1
Haynie, M1
Schelbert, HR1
Czernin, J1
Chilian, WM1
Clozel, JP1
Hefti, F1
DePuey, EG1
Guertler-Krawczynska, E1
Perkins, JV1
Robbins, WL1
Whelchel, JD1
Clements, SD1
Swan, H1
Meagher, DM1
Wussling, M1
Szymanski, G1
Schrör, K1

Reviews

1 review available for dipyridamole and Cardiomegaly

ArticleYear
[Quantitative determination of coronary reserve in diagnosis of coronary circulatory disorders].
    Der Internist, 1977, Volume: 18, Issue:11

    Topics: Adrenergic beta-Antagonists; Cardiomegaly; Cardiomyopathies; Collagen Diseases; Coronary Circulation

1977

Other Studies

29 other studies available for dipyridamole and Cardiomegaly

ArticleYear
[INVERSION OF THE CORONARY DILATOR EFFECT OF SOME DRUGS BY ERGOTAMINE TARTRATE].
    Revista espanola de fisiologia, 1963, Volume: 19

    Topics: Animals; Blood Circulation; Cardiomegaly; Coronary Vessels; Dipyridamole; Dogs; Ergotamine; Papaveri

1963
Effects of duration and severity of arterial hypertension and cardiac hypertrophy on coronary vasodilator reserve.
    Circulation research, 1982, Volume: 51, Issue:1

    Topics: Animals; Cardiomegaly; Coronary Circulation; Dipyridamole; Disease Models, Animal; Hypertension; Mal

1982
[Effect of tachycardia on hemodynamics and coronary circulation. Different relevance of ventricular tachycardias for healthy persons, coronary patients and patients with left heart hypertrophy].
    Fortschritte der Medizin, 1984, Oct-25, Volume: 102, Issue:40

    Topics: Aortic Valve; Aortic Valve Stenosis; Cardiac Pacing, Artificial; Cardiomegaly; Coronary Circulation;

1984
[Coronary circulation in patients with left ventricular hypertrophy].
    Revista medica de Chile, 1984, Volume: 112, Issue:5

    Topics: Blood Pressure; Cardiac Catheterization; Cardiomegaly; Coronary Circulation; Dipyridamole; Echocardi

1984
An unusual case of Bjork-Shiley mitral valve dysfunction corrected nonsurgically.
    Chest, 1981, Volume: 80, Issue:4

    Topics: Aspirin; Cardiomegaly; Dipyridamole; Echocardiography; Female; Furosemide; Heart Murmurs; Heart Valv

1981
Regional thallium-201 washout and myocardial hypertrophy in hypertrophic cardiomyopathy and its relation to exertional chest pain.
    The American journal of cardiology, 1993, Jul-15, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Aged; Cardiomegaly; Cardiomyopathy, Hypertrophic; Chest Pain; Chi-Square Distribu

1993
Mechanisms of coronary flow reserve impairment in human hypertension. An integrated approach by transthoracic and transesophageal echocardiography.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Blood Flow Velocity; Blood Pressure; Cardiomegaly; Coronary Vessels; D

1997
Valsartan and coronary haemodynamics in early post-myocardial infarction in rats.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:6

    Topics: Administration, Oral; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Body Weigh

1999
[The effect of oxyfedrine, prenylamine and dipyridamole on heart hypertrophy and collagen concentration of pressure loaded rat hearts].
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 220, Issue:1

    Topics: Animals; Blood Pressure; Cardiomegaly; Collagen; Dipyridamole; Heart; Heart Rate; Myocardium; Oxyfed

1976
Influence of long-term treatment with dipyridamole on the aorta-stenosed rabbit heart: morphometric and functional investigations.
    Cardiovascular research, 1976, Volume: 10, Issue:5

    Topics: Animals; Aortic Valve Stenosis; Blood Pressure; Cardiomegaly; Dipyridamole; Disease Models, Animal;

1976
[Variation of mechanical and biochemical parameters of pressure-loaded rabbit hearts following chronic administration of dipyridamole].
    Acta biologica et medica Germanica, 1975, Volume: 34, Issue:11-12

    Topics: Animals; Cardiomegaly; Dipyridamole; Heart; Hemodynamics; Hydroxyproline; Myocardium; Rabbits

1975
Coronary blood flow and myocardial O2 consumption in hypertrophied cardiac muscle in dogs.
    Advances in cardiology, 1976, Volume: 18, Issue:0

    Topics: Animals; Cardiac Output; Cardiomegaly; Coronary Circulation; Dipyridamole; Dogs; Myocardium; Nitrogl

1976
Effect of dipyridamole on myocardial adenosine metabolism and coronary flow in hypoxia and reactive hyperemia in the isolated perfused guinea pig heart.
    Journal of molecular and cellular cardiology, 1976, Volume: 8, Issue:11

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiome

1976
[Circulatory and metabolic action of pressure-induced cardiac hypertrophy in rest, during exercise and following medicinal dilatation of the coronary vessels].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aortic Valve Stenosis; Cardiomegaly; Coronary Circulation; Dipyridamole; Humans; Lactates; Oxygen; P

1977
[Subendocardial jeopardy of the hypertrophied myocardium].
    Chirurgisches Forum fur experimentelle und klinische Forschung, 1979

    Topics: Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary Vessels; Dipyridamole; Dogs;

1979
Dipyridamole-induced capillary growth in normal and hypertrophic hearts.
    The American journal of physiology, 1992, Volume: 262, Issue:4 Pt 2

    Topics: Animals; Capillaries; Cardiomegaly; Coronary Circulation; Dipyridamole; Hypertension, Renal; Male; N

1992
A negative thallium (+/- dipyridamole) stress test excludes significant obstructive epicardial coronary artery disease in hypertensive patients.
    American journal of hypertension, 1992, Volume: 5, Issue:2

    Topics: Adult; Cardiomegaly; Coronary Angiography; Coronary Disease; Dipyridamole; Echocardiography; Exercis

1992
Dipyridamole-thallium tests are predictive of severe cardiac arrhythmias in patients with left ventricular hypertrophy.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 2

    Topics: Adolescent; Aged; Arrhythmias, Cardiac; Cardiomegaly; Dipyridamole; Female; Humans; Middle Aged; Pre

1991
Dipyridamole echocardiography stress testing in hypertensive patients. Targets and tools.
    Circulation, 1991, Volume: 83, Issue:5 Suppl

    Topics: Cardiomegaly; Coronary Disease; Dipyridamole; Echocardiography; Exercise; Humans; Hypertension; Micr

1991
Influence of left ventricular mass on the diagnostic accuracy of myocardial perfusion imaging using positron emission tomography with dipyridamole stress.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:12

    Topics: Adult; Aged; Cardiomegaly; Coronary Disease; Dipyridamole; Echocardiography; Female; Humans; Male; M

1991
Relations among impaired coronary flow reserve, left ventricular hypertrophy and thallium perfusion defects in hypertensive patients without obstructive coronary artery disease.
    Journal of the American College of Cardiology, 1990, Volume: 15, Issue:1

    Topics: Cardiac Catheterization; Cardiomegaly; Coronary Circulation; Coronary Disease; Dipyridamole; Echocar

1990
Limited myocardial perfusion reserve in patients with left ventricular hypertrophy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1990, Volume: 31, Issue:3

    Topics: Cardiomegaly; Coronary Circulation; Dipyridamole; Exercise; Female; Heart; Humans; Male; Nitrogen Ra

1990
Noninvasive quantification of regional myocardial blood flow: assessment of myocardial perfusion reserve and collateral circulation.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1990, Volume: 31, Issue:3

    Topics: Cardiomegaly; Collateral Circulation; Coronary Circulation; Coronary Disease; Dipyridamole; Exercise

1990
Thyroxine-induced left ventricular hypertrophy in the rat. Anatomical and physiological evidence for angiogenesis.
    Circulation research, 1985, Volume: 57, Issue:4

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Body Weight; Capillaries; Cardiomegaly; Coronary Circu

1985
Cilazapril prevents the development of cardiac hypertrophy and the decrease of coronary vascular reserve in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Cardiomegaly; Cilazapril; Coronary C

1988
Alterations in myocardial thallium-201 distribution in patients with chronic systemic hypertension undergoing single-photon emission computed tomography.
    The American journal of cardiology, 1988, Aug-01, Volume: 62, Issue:4

    Topics: Cardiomegaly; Diagnosis, Differential; Dipyridamole; Echocardiography; Female; Heart; Humans; Hypert

1988
Total body bypass in miniature pigs. Postperfusion pulmonary hypertension.
    The Journal of thoracic and cardiovascular surgery, 1971, Volume: 61, Issue:6

    Topics: Acidosis; Anesthesia, Inhalation; Animals; Blood Group Incompatibility; Blood Pressure; Capillary Pe

1971
[Influence of long-term treatment with dipyridamole on the contractility and development of hypertrophy in rabbit heart with aortic stenois].
    Acta biologica et medica Germanica, 1972, Volume: 28, Issue:5

    Topics: Animals; Aortic Valve Stenosis; Blood Pressure; Body Weight; Cardiomegaly; Dipyridamole; Female; Hea

1972
The influence of hypertrophy and hypoxia on potentiation phenomena of the rabbit papillary muscle tested by a double rest programme.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Animals; Aortic Valve Stenosis; Calcium; Cardiomegaly; Dipyridamole; Electric Stimulation; Heart Ven

1974