Page last updated: 2024-10-26

dipyridamole and Carcinoma 256, Walker

dipyridamole has been researched along with Carcinoma 256, Walker in 11 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Dipyridamole is a non-specific inhibitor of nucleoside transport into mammalian cells."1.27The effect of the nucleoside transport inhibitor dipyridamole on the incorporation of [3H]thymidine in the rat. ( Calvert, AH; Harrap, KR; Newell, DR; O'Connor, PM, 1986)
"Uridine transport in a variant (NRM) of Novikoff hepatoma cells, in HTC rat hepatoma cells, normal rat kidney (NRK) cells, rat erythrocytes and rat hepatocytes was inhibited 15-60% by 10-500 nM NBTI and the cells expressed high-affinity NBTI-binding sites (Kd = 0."1.27Nitrobenzylthioinosine-sensitive and -resistant nucleoside transport in normal and transformed rat cells. ( Plagemann, PG; Wohlhueter, RM, 1985)
"The mechanism of the early stage of metastasis formation by sticky blood-born cancer cells is discussed."1.26Platelet-cancer cell interaction in metastasis formation: a possible therapeutic approcach to metastasis prophylaxis. ( Gastpar, H, 1977)
"Dipyridamole and ancrod pretreatment did not influence the decrease of platelets and their accumulation in the lung after tumour cell injection."1.25The role of blood platelets in experimental metastases. ( Hilgard, P, 1973)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gastpar, H6
Weissgerber, PW1
Ambrus, JL1
Ambrus, CM1
Crawford, CR1
Belt, JA2
Noel, LD1
Newell, DR1
O'Connor, PM1
Calvert, AH1
Harrap, KR1
Plagemann, PG1
Wohlhueter, RM1
Hilgard, P1

Other Studies

11 other studies available for dipyridamole and Carcinoma 256, Walker

ArticleYear
The inhibition of cancer cell stickiness: a model for investigation of platelet aggregation inhibitors in vivo. V. The effect of penbutolol.
    Journal of medicine, 1981, Volume: 12, Issue:1

    Topics: Animals; Carcinoma 256, Walker; Cell Aggregation; Chemical Phenomena; Chemistry; Depression, Chemica

1981
Platelet aggregation inhibitors in the prevention of metastasis in neoplastic disease: a review of experimental and clinical investigations.
    Journal of medicine, 1981, Volume: 12, Issue:1

    Topics: Animals; Bencyclane; Blood Coagulation; Carcinoma 256, Walker; Depression, Chemical; Dipyridamole; D

1981
Platelet-cancer cell interaction in metastasis formation: a possible therapeutic approcach to metastasis prophylaxis.
    Journal of medicine, 1977, Volume: 8, Issue:2

    Topics: Animals; Bencyclane; Blood Coagulation; Carcinoma 256, Walker; Cell Adhesion; Dipyridamole; Dissemin

1977
[Inhibition of the "cancer cell stickiness" using pentoxyphylline (Trental)].
    Die Medizinische Welt, 1976, Jan-16, Volume: 27, Issue:3

    Topics: Animals; Blood Coagulation; Carcinoma 256, Walker; Dipyridamole; Dose-Response Relationship, Drug; K

1976
Sodium-dependent, concentrative nucleoside transport in Walker 256 rat carcinosarcoma cells.
    Biochemical and biophysical research communications, 1991, Mar-29, Volume: 175, Issue:3

    Topics: Animals; Biological Transport; Carcinoma 256, Walker; Dipyridamole; Formycins; Inosine; Kinetics; Nu

1991
Nucleoside transport in Walker 256 rat carcinosarcoma and S49 mouse lymphoma cells. Differences in sensitivity to nitrobenzylthioinosine and thiol reagents.
    The Biochemical journal, 1985, Dec-15, Volume: 232, Issue:3

    Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport; Carcinoma 256, Walker; Cell Line; Di

1985
The effect of the nucleoside transport inhibitor dipyridamole on the incorporation of [3H]thymidine in the rat.
    Biochemical pharmacology, 1986, Nov-01, Volume: 35, Issue:21

    Topics: Animals; Binding Sites; Blood Proteins; Bone Marrow; Carcinoma 256, Walker; Digestive System; Dipyri

1986
Nitrobenzylthioinosine-sensitive and -resistant nucleoside transport in normal and transformed rat cells.
    Biochimica et biophysica acta, 1985, Jun-27, Volume: 816, Issue:2

    Topics: Animals; Binding Sites; Biological Transport; Carcinoma 256, Walker; Dipyridamole; Inosine; Kidney;

1985
The role of blood platelets in experimental metastases.
    British journal of cancer, 1973, Volume: 28, Issue:5

    Topics: Animals; Blood Cell Count; Blood Platelets; Carcinoma 256, Walker; Chromium; Chromium Isotopes; Dipy

1973
Inhibition of cancer cell stickiness by the blocking of platelet aggregation.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Mar-30, Volume: 48, Issue:15

    Topics: Adhesiveness; Animals; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Capillaries; Carcin

1974
The inhibition of the cancer stickiness by pyrimido-pyrimidine derivates induced by inhibition of platelet aggregation.
    Acta medica Scandinavica. Supplementum, 1971, Volume: 525

    Topics: Animals; Blood Platelets; Carcinoma 256, Walker; Cell Aggregation; Dipyridamole; Injections, Intrave

1971