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dipyridamole and Cancer of Prostate

dipyridamole has been researched along with Cancer of Prostate in 6 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"Dipyridamole (DIP) is a vasodilator and antithrombotic drug."1.51Dipyridamole impairs autophagic flux and exerts antiproliferative activity on prostate cancer cells. ( Guma, FT; Ilha, M; Lenz, G; Onzi, GR; Pereira, LC; Rohden, F; Thomé, MP; Wink, MR, 2019)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Longo, J1
Mullen, PJ1
Yu, R1
van Leeuwen, JE1
Masoomian, M1
Woon, DTS1
Wang, Y1
Chen, EX1
Hamilton, RJ1
Sweet, JM1
van der Kwast, TH1
Fleshner, NE1
Penn, LZ1
Thomé, MP1
Pereira, LC1
Onzi, GR1
Rohden, F1
Ilha, M1
Guma, FT1
Wink, MR1
Lenz, G1
Passer, BJ1
Cheema, T1
Zhou, B1
Wakimoto, H1
Zaupa, C1
Razmjoo, M1
Sarte, J1
Wu, S1
Wu, CL1
Noah, JW1
Li, Q1
Buolamwini, JK1
Yen, Y1
Rabkin, SD1
Martuza, RL1
Goda, AE1
Yoshida, T1
Horinaka, M1
Yasuda, T1
Shiraishi, T1
Wakada, M1
Sakai, T1
Koiso, K1
Akima, H1
Niijima, T1
Singh, D1
Doroshow, JH1
Leong, L1
Margolin, K1
Akman, S1
Raschko, J1
Somlo, G1
Morgan, R1
Harrison, J1
Cho, J1

Trials

1 trial available for dipyridamole and Cancer of Prostate

ArticleYear
Phase II trial of 5-fluorouracil, high-dose leucovorin calcium, and dipyridamole in advanced prostate cancer.
    Journal of cancer research and clinical oncology, 1992, Volume: 119, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Fluorouracil; Humans; Leucovorin

1992

Other Studies

5 other studies available for dipyridamole and Cancer of Prostate

ArticleYear
An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer.
    Molecular metabolism, 2019, Volume: 25

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dipyridamole; Drug Repos

2019
Dipyridamole impairs autophagic flux and exerts antiproliferative activity on prostate cancer cells.
    Experimental cell research, 2019, 09-01, Volume: 382, Issue:1

    Topics: Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Agents; Autophagosomes; Autophagy; Cell Divis

2019
Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication.
    Cancer research, 2010, May-15, Volume: 70, Issue:10

    Topics: Animals; Combinatorial Chemistry Techniques; Dilazep; Dipyridamole; Equilibrative Nucleoside Transpo

2010
Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole.
    Oncogene, 2008, May-29, Volume: 27, Issue:24

    Topics: Apoptosis; Blotting, Northern; Bone Neoplasms; Colonic Neoplasms; Cyclic AMP-Dependent Protein Kinas

2008
Prevention of platelet aggregation in patients with prostatic cancer during estrogen therapy.
    Urology, 1982, Volume: 19, Issue:6

    Topics: Aged; Blood Coagulation Tests; Blood Platelets; Cyclic AMP; Dipyridamole; Fibrinolysis; Hexestrol; H

1982