dipyridamole has been researched along with Brain Neoplasms in 4 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In C6 glioma cells, adenine nucleotides, especially AMP, and adenosine inhibited cell proliferation in time- and concentration-dependent manners." | 3.74 | Adenosine uptake-dependent C6 cell growth inhibition. ( Nagata, K; Nakahata, N; Ohkubo, S, 2007) |
| "Among ovarian cancer cell lines tested, the enhancement of the activity of HuIFN by dipyridamole for HAC-2 and SHIN-3 cells was equivalent to or greater than that for 3 chemotherapy agents (adriamycin, vincristine, and a camptothecin derivative)." | 1.28 | Dipyridamole enhances an anti-proliferative effect of interferon in various types of human tumor cells. ( Fukazawa, I; Inaba, N; Isogai, E; Oiwa, Y; Saito-Ebihara, M; Sekiya, S; Sugano, I; Suzuki, N; Takakubo, Y; Yoshida, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohkubo, S | 1 |
| Nagata, K | 1 |
| Nakahata, N | 1 |
| Caciagli, F | 1 |
| Ciccarelli, R | 1 |
| Ciancetta, S | 1 |
| Di Iorio, P | 1 |
| Caciagli, P | 1 |
| Stewart, DJ | 1 |
| Dahrouge, S | 1 |
| Agboola, O | 1 |
| Girard, A | 1 |
| Suzuki, N | 1 |
| Oiwa, Y | 1 |
| Sugano, I | 1 |
| Inaba, N | 1 |
| Sekiya, S | 1 |
| Fukazawa, I | 1 |
| Yoshida, J | 1 |
| Takakubo, Y | 1 |
| Isogai, E | 1 |
| Saito-Ebihara, M | 1 |
1 trial available for dipyridamole and Brain Neoplasms
| Article | Year |
|---|---|
Cranial radiation and concomitant cisplatin and mitomycin-C plus resistance modulators for malignant gliomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta Carotene; Brain Neoplasms; Cisplat | 1997 |
3 other studies available for dipyridamole and Brain Neoplasms
| Article | Year |
|---|---|
Adenosine uptake-dependent C6 cell growth inhibition.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosi | 2007 |
Adenosine--norepinephrine interactions on cyclic AMP generating system in human tumoral brain slices.
Topics: Adenosine; Adult; Aged; Brain Neoplasms; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; | 1982 |
Dipyridamole enhances an anti-proliferative effect of interferon in various types of human tumor cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cell Div | 1992 |