Page last updated: 2024-10-26

dipyridamole and Body Weight

dipyridamole has been researched along with Body Weight in 28 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Effects of beraprost sodium, a chemically stable prostacyclin analogue, on renal dysfunction in an experimental rat model of glomerulonephritis were investigated."7.71Amelioration by beraprost sodium, a prostacyclin analogue, of established renal dysfunction in rat glomerulonephritis model. ( Kurumatani, H; Matsushita, T; Sasaki, R; Sato, N; Suzuki, M; Tamura, M; Yamada, M, 2002)
"Furthermore."5.30Valsartan and coronary haemodynamics in early post-myocardial infarction in rats. ( De Gasparo, M; Fornes, P; Gervais, M; Giudicelli, JF; Richer, C, 1999)
"Effects of beraprost sodium, a chemically stable prostacyclin analogue, on renal dysfunction in an experimental rat model of glomerulonephritis were investigated."3.71Amelioration by beraprost sodium, a prostacyclin analogue, of established renal dysfunction in rat glomerulonephritis model. ( Kurumatani, H; Matsushita, T; Sasaki, R; Sato, N; Suzuki, M; Tamura, M; Yamada, M, 2002)
"We evaluate 1,271 patients from the Thrombolysis in Myocardial Infarction (TIMI)-IIIB trial (86% of TIMI-IIIB cohort) with unstable angina or non-Q wave myocardial infarction, who underwent predischarge exercise (92%) or dipyridamole stress (8%) Tl-201 imaging."3.69Relevance of increased lung thallium uptake on stress imaging in patients with unstable angina and non-Q wave myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI)-IIIB Study. ( Jain, D; Thompson, B; Wackers, FJ; Zaret, BL, 1997)
"In this study, we investigated the antinephritic effects of TJ-8014 and crude drugs in TJ-8014, in comparison to dipyridamole, on original-type anti-GBM nephritis in rats."3.67Studies on antinephritic effect of TJ-8014, a new Japanese herbal medicine, and its mechanisms (1): Effects on original-type anti-GBM nephritis in rats and platelet aggregation. ( Hattori, T; Ito, M; Nagamatsu, T; Suzuki, Y, 1989)
"Five aspirin preparations were evaluated, 3 different enteric-coated 75-mg aspirins, dispersible aspirin 75 mg and asasantin (25-mg standard release aspirin plus 200-mg modified-release dipyridamole given twice daily)."2.72Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. ( Byrne, MF; Conroy, R; Cox, D; Dooley, M; Fitzgerald, DJ; Maree, AO, 2006)
"Therefore, glibenclamide treatment of Type 2 diabetes mellitus may have hazardous cardiovascular effects when used under conditions of ischaemia."2.70Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients. ( Abbink, EJ; Jansen van Rosendaal, A; Lutterman, JA; Pickkers, P; Russel, FG; Smits, P; Tack, CJ, 2002)
" Proportional dosing resulted in decreasing CNR, SNR, and visual IQS with increasing body weight (P < 0."1.91Exponential dosing to standardize myocardial perfusion image quality with rubidium-82 PET. ( Beanlands, RSB; deKemp, RA; Khetarpal, R; Tavoosi, A; Wells, RG, 2023)
"Dipyridamole treatment prevented the development of abnormal left ventricular chamber filling, preserved adrenergic responsiveness and appeared to attenuate detrimental chamber remodeling in rats with pressure overload hypertrophy."1.30Effects of chronic adenosine uptake blockade on adrenergic responsiveness and left ventricular chamber function in pressure overload hypertrophy in the rat. ( Aurigemma, GP; Chung, ES; Dobson, JG; Fenton, RA; Meyer, TE; Perlini, S, 1998)
"Furthermore."1.30Valsartan and coronary haemodynamics in early post-myocardial infarction in rats. ( De Gasparo, M; Fornes, P; Gervais, M; Giudicelli, JF; Richer, C, 1999)
"The mean value of the thrombus area in the dilazep group was 60% smaller and the distribution pattern of the thrombus by size was found to be composed of smaller thrombi than those of the control group."1.28Thrombus formation on the aorta injured by angioplasty and its prevention with dilazep in atherosclerotic rabbits. ( Asanuma, A; Fujii, M; Nobuyoshi, M; Takimoto, M; Tanaka, M, 1989)
" In addition, treatment with dipyridamole also reduced the growth inhibitory effects of cytarabine on HL-60 cells in culture and protected mice from toxic doses of this antimetabolite."1.27Modulation of cytarabine uptake and toxicity by dipyridamole. ( Howell, SB; King, ME; Naporn, A; Young, B, 1984)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199016 (57.14)18.7374
1990's7 (25.00)18.2507
2000's4 (14.29)29.6817
2010's0 (0.00)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Tavoosi, A1
Khetarpal, R1
Wells, RG1
Beanlands, RSB1
deKemp, RA1
Yamada, M1
Sasaki, R1
Sato, N1
Suzuki, M1
Tamura, M1
Matsushita, T1
Kurumatani, H1
Chen, P1
Chien, PY1
Khan, AR1
Sheikh, S1
Ali, SM1
Ahmad, MU1
Ahmad, I1
Cox, D1
Maree, AO1
Dooley, M1
Conroy, R1
Byrne, MF1
Fitzgerald, DJ1
Tornling, G4
Adolfsson, J4
Unge, G3
Ljungqvist, A3
King, ME1
Naporn, A1
Young, B1
Howell, SB1
Carlsson, S2
Tomanek, RJ2
Barlow, PA1
Connell, PM1
Chen, Y1
Torry, RJ1
Hofer, M1
Pospísil, M1
Netíková, J1
Znojil, V1
Vácha, J1
Holá, J1
Kwok, CG1
Wu, S1
Tsang, HP1
Strauss, HW1
Jain, D1
Thompson, B1
Wackers, FJ1
Zaret, BL1
Chung, ES1
Perlini, S1
Aurigemma, GP1
Fenton, RA1
Dobson, JG1
Meyer, TE1
Gervais, M1
Richer, C1
Fornes, P1
De Gasparo, M1
Giudicelli, JF1
Abbink, EJ1
Pickkers, P1
Jansen van Rosendaal, A1
Lutterman, JA1
Tack, CJ1
Russel, FG1
Smits, P1
Skoog, L1
Okada, N1
Aizawa, T1
Yokokawa, N1
Kobayashi, M1
Moriya, T1
Shigematsu, S1
Shirota, T1
Komatsu, M1
Shinoda, T1
Yamada, T1
Chilian, WM1
Wangler, RD1
Peters, KG1
Marcus, ML1
Clozel, JP1
Hefti, F1
Nobuyoshi, M1
Tanaka, M1
Fujii, M1
Asanuma, A1
Takimoto, M1
Hattori, T1
Nagamatsu, T1
Ito, M1
Suzuki, Y1
Camp, A1
Chaitman, BR1
Goodgold, H1
Byers, S1
Shaw, L1
Barth, G1
Samuels, L1
Verbeuren, TJ1
Coene, MC1
Jordaens, FH1
Van Hove, CE1
Zonnekeyn, LL1
Herman, AG1
Triebe, G1
Blass, KE1
Förster, W1
Kobayakawa, T1
Takenaka, F1
Takeya, N1
Ishihara, T1
Higuchi, M1
Hayashi, H1
Ando, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Enteric Coating as a Factor in Aspirin Resistance[NCT00531362]250 participants (Actual)Observational2007-09-30Completed
[NCT00000472]Phase 30 participants Interventional1989-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for dipyridamole and Body Weight

ArticleYear
Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers.
    Stroke, 2006, Volume: 37, Issue:8

    Topics: Adult; Aspirin; Aspirin, Dipyridamole Drug Combination; Body Weight; Cross-Over Studies; Dipyridamol

2006
Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients.
    Diabetic medicine : a journal of the British Diabetic Association, 2002, Volume: 19, Issue:2

    Topics: Acetylcholine; Adult; Aged; Blood Flow Velocity; Blood Pressure; Body Mass Index; Body Weight; C-Pep

2002

Other Studies

26 other studies available for dipyridamole and Body Weight

ArticleYear
Exponential dosing to standardize myocardial perfusion image quality with rubidium-82 PET.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023, Volume: 30, Issue:6

    Topics: Body Weight; Coronary Artery Disease; Dipyridamole; Humans; Myocardial Perfusion Imaging; Positron-E

2023
Amelioration by beraprost sodium, a prostacyclin analogue, of established renal dysfunction in rat glomerulonephritis model.
    European journal of pharmacology, 2002, Aug-02, Volume: 449, Issue:1-2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Blood Pressure; Blood U

2002
In-vitro and in-vivo anti-cancer activity of a novel gemcitabine-cardiolipin conjugate.
    Anti-cancer drugs, 2006, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Body Weight; Cardiolipins; Cell Proliferation; Deoxycytidine; Dipyri

2006
Capillary neoformation in skeletal muscle of dipyridamole-treated rats.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:5

    Topics: Animals; Body Weight; Capillaries; Dipyridamole; Male; Muscles; Neovascularization, Pathologic; Rats

1980
Modulation of cytarabine uptake and toxicity by dipyridamole.
    Cancer treatment reports, 1984, Volume: 68, Issue:2

    Topics: Animals; Biological Transport; Body Weight; Cell Line; Cytarabine; Dipyridamole; Drug Evaluation, Pr

1984
Capillary neoformation in the heart and skeletal muscle during dipyridamole--treatment and exercise.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Supplement, 1982, Volume: 278

    Topics: Animals; Body Weight; Capillaries; Cell Division; Coronary Vessels; Dipyridamole; DNA Replication; F

1982
Proliferative activity of capillary wall cells in skeletal muscle of rats during long-term treatment with dipyridamole.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:4

    Topics: Aging; Animals; Autoradiography; Body Weight; Capillaries; Cell Division; Dipyridamole; DNA; Female;

1980
Effects of hypothyroidism and hypertension on myocardial perfusion and vascularity in rabbits.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2

    Topics: Animals; Arterioles; Blood Pressure; Body Weight; Coronary Circulation; Coronary Vessels; Dipyridamo

1993
Radioprotective efficacy of dipyridamole and AMP combination in fractionated radiation regimen, and its dependence on the time of administration of the drugs prior to irradiation.
    Physiological research, 1995, Volume: 44, Issue:2

    Topics: Adenosine Monophosphate; Animals; Body Weight; Cell Division; Dipyridamole; Drug Administration Sche

1995
Feasibility of simultaneous dual-isotope myocardial perfusion acquisition using a lower dose of sestamibi.
    European journal of nuclear medicine, 1997, Volume: 24, Issue:3

    Topics: Body Weight; Coronary Disease; Dipyridamole; Exercise Test; Feasibility Studies; Female; Heart; Huma

1997
Relevance of increased lung thallium uptake on stress imaging in patients with unstable angina and non-Q wave myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI)-IIIB Study.
    Journal of the American College of Cardiology, 1997, Volume: 30, Issue:2

    Topics: Angina, Unstable; Body Weight; Cardiac Catheterization; Dipyridamole; Exercise Tolerance; Female; Fo

1997
Effects of chronic adenosine uptake blockade on adrenergic responsiveness and left ventricular chamber function in pressure overload hypertrophy in the rat.
    Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 1

    Topics: Adenosine; Animals; Blood Pressure; Body Weight; Dipyridamole; Heart; Hypertrophy, Left Ventricular;

1998
Valsartan and coronary haemodynamics in early post-myocardial infarction in rats.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:6

    Topics: Administration, Oral; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Body Weigh

1999
Proliferative activity of myocardial capillary wall cells in dipyridamole--treated rats.
    Cardiovascular research, 1978, Volume: 12, Issue:11

    Topics: Animals; Body Weight; Capillaries; Cell Division; Coronary Vessels; Dipyridamole; Female; Heart; Mal

1978
Abnormal molecular weight profile of urinary protein in rats with streptozotocin-induced diabetes.
    Diabetes research and clinical practice, 1992, Volume: 18, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dipyridamole; Electrophoresis,

1992
Thyroxine-induced left ventricular hypertrophy in the rat. Anatomical and physiological evidence for angiogenesis.
    Circulation research, 1985, Volume: 57, Issue:4

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Body Weight; Capillaries; Cardiomegaly; Coronary Circu

1985
Cilazapril prevents the development of cardiac hypertrophy and the decrease of coronary vascular reserve in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Cardiomegaly; Cilazapril; Coronary C

1988
Thrombus formation on the aorta injured by angioplasty and its prevention with dilazep in atherosclerotic rabbits.
    Thrombosis research, 1989, Jun-15, Volume: 54, Issue:6

    Topics: Angioplasty, Balloon; Animals; Aorta; Arteriosclerosis; Azepines; Body Weight; Cholesterol; Dilazep;

1989
Studies on antinephritic effect of TJ-8014, a new Japanese herbal medicine, and its mechanisms (1): Effects on original-type anti-GBM nephritis in rats and platelet aggregation.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:4

    Topics: Animals; Antibodies; Basement Membrane; Blood Urea Nitrogen; Body Weight; Dipyridamole; Drugs, Chine

1989
Intravenous dipyridamole: body weight considerations and dosage requirements.
    American heart journal, 1989, Volume: 117, Issue:3

    Topics: Adult; Aged; Body Weight; Coronary Disease; Dipyridamole; Dose-Response Relationship, Drug; Exercise

1989
Time dependence of dipyridamole-induced increase in skeletal muscle capillarization.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:12

    Topics: Animals; Body Weight; Capillaries; Dipyridamole; Heart; In Vitro Techniques; Male; Muscles; Organ Si

1986
Effect of hypercholesterolemia on vascular reactivity in the rabbit. II. Influence of treatment with dipyridamole on endothelium-dependent and endothelium-independent responses in isolated aortas of control and hypercholesterolemic rabbits.
    Circulation research, 1986, Volume: 59, Issue:5

    Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol; Cholesterol, Dietary; Dipyridamole; Hype

1986
[Influence of long-term treatment with dipyridamole on the contractility and development of hypertrophy in rabbit heart with aortic stenois].
    Acta biologica et medica Germanica, 1972, Volume: 28, Issue:5

    Topics: Animals; Aortic Valve Stenosis; Blood Pressure; Body Weight; Cardiomegaly; Dipyridamole; Female; Hea

1972
[Experimental study on drugs for the treatment of myocardial infarction].
    Japanese circulation journal, 1972, Volume: 36, Issue:1

    Topics: Angiography; Animals; Benzyl Compounds; Body Weight; Carboxylic Acids; Dipyridamole; Disease Models,

1972
Toxicological studies on dipyridamole in the rat.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:5

    Topics: Administration, Oral; Animals; Body Weight; Dipyridamole; Feeding Behavior; Female; Injections, Intr

1972
[Experimental studies on selective coronary artery infusion].
    Japanese circulation journal, 1968, Volume: 32, Issue:3

    Topics: Angiocardiography; Animals; Blood Pressure; Body Weight; Coloring Agents; Contrast Media; Coronary A

1968