Page last updated: 2024-10-26

dipyridamole and Bipolar Disorder

dipyridamole has been researched along with Bipolar Disorder in 6 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Dihydropyridines and diltiazem were associated with a decreased risk of psychiatric hospitalization in bipolar disorder."8.12Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study. ( Lähteenvuo, M; Lintunen, J; Taipale, H; Tanskanen, A; Tiihonen, J, 2022)
"Dihydropyridines and diltiazem were associated with a decreased risk of psychiatric hospitalization in bipolar disorder."4.12Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study. ( Lähteenvuo, M; Lintunen, J; Taipale, H; Tanskanen, A; Tiihonen, J, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Lintunen, J1
Lähteenvuo, M1
Tanskanen, A1
Tiihonen, J1
Taipale, H1
Nosengo, N1
Machado-Vieira, R1
Soares, JC1
Lara, DR1
Luckenbaugh, DA1
Busnello, JV1
Marca, G1
Cunha, A1
Souza, DO1
Zarate, CA1
Kapczinski, F1
BARCIASALORIO, D1
BORREGUERO, AD1
Lereboullet, J1
Rosa, A1
Olivier-Martin, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind, Randomized, Placebo-controlled 4-week Study on the Efficacy and Safety of the Purinergic Agents Allopurinol and Dipyridamole in Acute Bipolar Mania.[NCT00560079]Phase 4180 participants (Actual)Interventional2003-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for dipyridamole and Bipolar Disorder

ArticleYear
A double-blind, randomized, placebo-controlled 4-week study on the efficacy and safety of the purinergic agents allopurinol and dipyridamole adjunctive to lithium in acute bipolar mania.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Allopurinol; Antipsychotic Agents; Bipolar Disorder; Diagnos

2008

Other Studies

5 other studies available for dipyridamole and Bipolar Disorder

ArticleYear
Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study.
    Journal of affective disorders, 2022, 09-15, Volume: 313

    Topics: Adenosine; Allopurinol; Bipolar Disorder; Calcium Channel Blockers; Cohort Studies; Dihydropyridines

2022
Can you teach old drugs new tricks?
    Nature, 2016, 06-16, Volume: 534, Issue:7607

    Topics: Animals; Azoles; Bipolar Disorder; Carbazoles; Clinical Trials, Phase II as Topic; Dipyridamole; Dru

2016
[STUDY OF CEREBRAL HEMODYNAMICS IN THE DEPRESSIVE STATES].
    Medicina espanola, 1963, Volume: 50

    Topics: Amitriptyline; Bipolar Disorder; Cerebrovascular Circulation; Depression; Depressive Disorder; Depre

1963
[TREATMENT OF DEPRESSION WITH PERSANTIN].
    Medicina espanola, 1964, Volume: 51

    Topics: Bipolar Disorder; Convulsive Therapy; Depression; Depressive Disorder; Dipyridamole; Electroconvulsi

1964
[Neuropsychiatry in 1973].
    La Revue du praticien, 1973, Apr-21, Volume: 23, Issue:23

    Topics: Aspirin; Bipolar Disorder; Dipyridamole; Heart Diseases; Humans; Hydrocephalus; Hypoxia, Brain; Isch

1973