dipyridamole has been researched along with Astrocytoma in 3 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In human D384 astrocytoma cells, cyclic AMP accumulation can be conveniently studied after labelling of the adenosine triphosphate pool (15 fmol cell-1) with [3H]adenine." | 7.68 | Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon. ( Altiok, N; Balmforth, AJ; Fredholm, BB, 1992) |
| "In human D384 astrocytoma cells, cyclic AMP accumulation can be conveniently studied after labelling of the adenosine triphosphate pool (15 fmol cell-1) with [3H]adenine." | 3.68 | Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon. ( Altiok, N; Balmforth, AJ; Fredholm, BB, 1992) |
| "The characteristics of the effects of catecholamines, prostaglandins, and adenosine on the adenosine 3',5'-monophosphate (cAMP) content of human astrocytoma cells are described." | 3.65 | Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells. ( Clark, RB; Cubeddu, L; Johnson, GL; Ortmann, R; Perkins, JP; Su, YF, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, RB | 1 |
| Su, YF | 1 |
| Ortmann, R | 1 |
| Cubeddu, L | 1 |
| Johnson, GL | 1 |
| Perkins, JP | 1 |
| Altiok, N | 1 |
| Balmforth, AJ | 1 |
| Fredholm, BB | 1 |
| Kum, W | 1 |
| Cockram, CS | 1 |
| Zhu, SQ | 1 |
| Teoh, R | 1 |
| Young, JD | 1 |
3 other studies available for dipyridamole and Astrocytoma
| Article | Year |
|---|---|
Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Astrocytoma; Catecholamines; Cells, Cultured; Cyclic AM | 1975 |
Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon.
Topics: Adenine; Adenine Nucleotides; Astrocytoma; Bradykinin; Cyclic AMP; Dipyridamole; Humans; In Vitro Te | 1992 |
Insulin binding to human astrocytoma cells and its effect on uridine incorporation into nucleic acid.
Topics: Astrocytoma; Cell Line; Dipyridamole; Dose-Response Relationship, Drug; Glucagon; Humans; Insulin; K | 1989 |