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dipyridamole and Aortic Valve Stenosis

dipyridamole has been researched along with Aortic Valve Stenosis in 25 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.

Research Excerpts

ExcerptRelevanceReference
"The sensitivity and specificity of non-invasive methods--specifically single-photon emission computed tomography (SPECT) dipyridamole-thallium myocardial perfusion--for detecting coronary artery disease (CAD) in patients with severe aortic stenosis remains unclear."9.09SPECT dipyridamole scintigraphy for detecting coronary artery disease in patients with isolated severe aortic stenosis. ( Avakian, SD; Grinberg, M; Mansur, AP; Meneguetti, JC; Ramires, JA, 2001)
"The high-dose dipyridamole echocardiography test was performed in 52 patients with severe aortic stenosis; all patients also underwent coronary angiography, independent of test results, before cardiac operation."7.70Preoperative assessment of coronary artery disease in aortic stenosis: a dipyridamole echocardiographic study. ( Baroni, M; Biagini, A; Ferrazzi, P; Maffei, S; Paoli, F; Terrazzi, M, 1998)
"Dipyridamole echocardiography in patients with aortic stenosis is safe and feasible with good sensitivity and better specificity."7.70[The role of the echo-dipyridamole test in the diagnosis of coronary disease in patients with associated aortic stenosis]. ( Amadei, G; Baggioni, GF; Carioli, E; Kubbajeh, M, 2000)
"Dipyridamole SPECT detects significant coronary artery disease (CAD) in patients without aortic stenosis."7.69Computer-assisted evaluation of dipyridamole thallium-201 SPECT in patients with aortic stenosis. ( Edlund, B; Eriksson, P; Karp, K; Mooe, T; Rask, P; Wiklund, U, 1994)
"Dipyridamole single-photon emission tomography (SPET) is used for the detection of coronary artery disease (CAD) and the method has also been applied in patients with aortic stenosis."7.69Dipyridamole thallium-201 single-photon emission tomography in aortic stenosis: gender differences. ( Eriksson, NP; Karp, KH; Mooe, T; Rask, LP, 1995)
"Dipyridamole echocardiography is a suitable clinical technique for assessing the ischaemic vulnerability of the left ventricle in severe aortic valve stenosis with angiographically normal coronary arteries."7.69Mechanisms of regional ischaemic changes during dipyridamole echocardiography in patients with severe aortic valve stenosis and normal coronary arteries. ( Baroni, M; Biagini, A; Maffei, S; Palmieri, C; Paoli, F; Terrazzi, M, 1996)
"Dipyridamole is a potent vasodilator used in pharmacologic stress testing."6.67Hemodynamic changes during dipyridamole stress in patients with aortic stenosis. ( Karp, KH; Rask, LP; Teien, DE, 1994)
" Relationships between the severity of AS, clinical characteristics, hemodynamic response, serious adverse events (SAE) and MPI parameters were analyzed."5.51The clinical value and safety of ECG-gated dipyridamole myocardial perfusion imaging in patients with aortic stenosis. ( Liu, FS; Shiau, YC; Wang, SY; Wu, YW, 2019)
" We conclude that DPT is safe in patients with aortic valve stenosis and angina pectoris."5.30The safety of dipyridamole-thallium imaging in patients with critical aortic valve stenosis and angina. ( Bourke, JP; Hawkins, T; Roy, S, 1998)
"The sensitivity and specificity of non-invasive methods--specifically single-photon emission computed tomography (SPECT) dipyridamole-thallium myocardial perfusion--for detecting coronary artery disease (CAD) in patients with severe aortic stenosis remains unclear."5.09SPECT dipyridamole scintigraphy for detecting coronary artery disease in patients with isolated severe aortic stenosis. ( Avakian, SD; Grinberg, M; Mansur, AP; Meneguetti, JC; Ramires, JA, 2001)
"Fifteen patients with severe aortic stenosis, normal coronary arteries and normal left ventricular systolic function (ejection fraction>50%) underwent a resting/dipyridamole (0."3.74Coronary flow reserve in severe aortic valve stenosis: a positron emission tomography study. ( Carpeggiani, C; Glauber, M; L'Abbate, A; Neglia, D; Paradossi, U; Pratali, L, 2008)
"The high-dose dipyridamole echocardiography test was performed in 52 patients with severe aortic stenosis; all patients also underwent coronary angiography, independent of test results, before cardiac operation."3.70Preoperative assessment of coronary artery disease in aortic stenosis: a dipyridamole echocardiographic study. ( Baroni, M; Biagini, A; Ferrazzi, P; Maffei, S; Paoli, F; Terrazzi, M, 1998)
"Dipyridamole echocardiography in patients with aortic stenosis is safe and feasible with good sensitivity and better specificity."3.70[The role of the echo-dipyridamole test in the diagnosis of coronary disease in patients with associated aortic stenosis]. ( Amadei, G; Baggioni, GF; Carioli, E; Kubbajeh, M, 2000)
"Dipyridamole SPECT detects significant coronary artery disease (CAD) in patients without aortic stenosis."3.69Computer-assisted evaluation of dipyridamole thallium-201 SPECT in patients with aortic stenosis. ( Edlund, B; Eriksson, P; Karp, K; Mooe, T; Rask, P; Wiklund, U, 1994)
"Dipyridamole single-photon emission tomography (SPET) is used for the detection of coronary artery disease (CAD) and the method has also been applied in patients with aortic stenosis."3.69Dipyridamole thallium-201 single-photon emission tomography in aortic stenosis: gender differences. ( Eriksson, NP; Karp, KH; Mooe, T; Rask, LP, 1995)
"Dipyridamole echocardiography is a suitable clinical technique for assessing the ischaemic vulnerability of the left ventricle in severe aortic valve stenosis with angiographically normal coronary arteries."3.69Mechanisms of regional ischaemic changes during dipyridamole echocardiography in patients with severe aortic valve stenosis and normal coronary arteries. ( Baroni, M; Biagini, A; Maffei, S; Palmieri, C; Paoli, F; Terrazzi, M, 1996)
"In a prospective study, the efficacy of a dipyridamole-aspirin regimen in prevention of thromboembolism was evaluated in 50 patients having isolated aortic valve replacement with the Model 2320 Starr-Edwards prosthesis."3.66Dipyridamole-aspirin as thromboembolic prophylaxis in patients with aortic valve prosthesis. Prospective study with the Model 2320 Starr-Edwards prosthesis. ( Bowen, TE; Brott, WH; Davia, J; Green, DC; Zajtchuk, R, 1981)
"Dipyridamole is a potent vasodilator used in pharmacologic stress testing."2.67Hemodynamic changes during dipyridamole stress in patients with aortic stenosis. ( Karp, KH; Rask, LP; Teien, DE, 1994)
" Relationships between the severity of AS, clinical characteristics, hemodynamic response, serious adverse events (SAE) and MPI parameters were analyzed."1.51The clinical value and safety of ECG-gated dipyridamole myocardial perfusion imaging in patients with aortic stenosis. ( Liu, FS; Shiau, YC; Wang, SY; Wu, YW, 2019)
" We conclude that DPT is safe in patients with aortic valve stenosis and angina pectoris."1.30The safety of dipyridamole-thallium imaging in patients with critical aortic valve stenosis and angina. ( Bourke, JP; Hawkins, T; Roy, S, 1998)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199010 (40.00)18.7374
1990's7 (28.00)18.2507
2000's7 (28.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, FS1
Wang, SY1
Shiau, YC1
Wu, YW1
Carpeggiani, C1
Neglia, D1
Paradossi, U1
Pratali, L1
Glauber, M1
L'Abbate, A1
Nemes, A3
Forster, T3
Varga, A1
Vass, A1
Borthaiser, A1
Pálinkás, A1
Csanády, M3
Kovács, Z2
Thury, A2
Ungi, I1
Boda, K1
Thormann, J1
Brott, WH1
Zajtchuk, R1
Bowen, TE1
Davia, J1
Green, DC1
Rask, LP2
Karp, KH2
Teien, DE1
Rask, P1
Karp, K1
Edlund, B1
Eriksson, P1
Mooe, T2
Wiklund, U1
Eriksson, NP1
Baroni, M2
Maffei, S2
Terrazzi, M2
Palmieri, C1
Paoli, F2
Biagini, A2
Ferrazzi, P1
Roy, S1
Hawkins, T1
Bourke, JP1
Amadei, G1
Carioli, E1
Kubbajeh, M1
Baggioni, GF1
Avakian, SD1
Grinberg, M1
Meneguetti, JC1
Ramires, JA1
Mansur, AP1
Demirkol, MO1
Yaymaci, B1
Debeş, H1
Başaran, Y1
Turan, F1
Blass, KE2
Triebe, G2
Traub, F1
Förster, W2
Kupper, W1
Bleifeld, W1
Hanrath, P1
Hamm, C1
Mathey, D1
Steele, P1
Weily, H1
Davies, H1
Ppppas, G1
Genton, E1
Georgeson, S1
Meyer, KB1
Pauker, SG1
Huikuri, HV1
Korhonen, UR1
Ikäheimo, MJ1
Heikkilä, J1
Takkunen, JT1
Mackay, A1
de Bono, DP1
Wussling, M1
Szymanski, G1
Schrör, K1
Matloff, JM1

Reviews

1 review available for dipyridamole and Aortic Valve Stenosis

ArticleYear
Surgery for aortic valve disease.
    Cardiovascular clinics, 1971, Volume: 3, Issue:2

    Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Animals; Anticoagulants; Aortic Valve Insufficienc

1971

Trials

3 trials available for dipyridamole and Aortic Valve Stenosis

ArticleYear
Hemodynamic changes during dipyridamole stress in patients with aortic stenosis.
    The Journal of heart valve disease, 1994, Volume: 3, Issue:5

    Topics: Aged; Aortic Valve Stenosis; Blood Pressure; Cardiac Catheterization; Cardiac Output; Dipyridamole;

1994
SPECT dipyridamole scintigraphy for detecting coronary artery disease in patients with isolated severe aortic stenosis.
    International journal of cardiology, 2001, Volume: 81, Issue:1

    Topics: Aged; Aortic Valve Stenosis; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Dipyrida

2001
Dipyridamole myocardial perfusion tomography in patients with severe aortic stenosis.
    Cardiology, 2002, Volume: 97, Issue:1

    Topics: Aged; Aortic Valve Stenosis; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Di

2002

Other Studies

21 other studies available for dipyridamole and Aortic Valve Stenosis

ArticleYear
The clinical value and safety of ECG-gated dipyridamole myocardial perfusion imaging in patients with aortic stenosis.
    Scientific reports, 2019, 08-27, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Dipyridamole; Electrocardiography; Female; Follow-Up

2019
Coronary flow reserve in severe aortic valve stenosis: a positron emission tomography study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2008, Volume: 9, Issue:9

    Topics: Aged; Aortic Valve; Aortic Valve Stenosis; Coronary Circulation; Dipyridamole; Echocardiography, Dop

2008
How can coronary flow reserve be altered by severe aortic stenosis?
    Echocardiography (Mount Kisco, N.Y.), 2002, Volume: 19, Issue:8

    Topics: Adult; Aged; Aortic Valve Stenosis; Arteries; Blood Pressure; Coronary Artery Disease; Coronary Circ

2002
The effect of aortic valve replacement on coronary flow reserve in patients with a normal coronary angiogram.
    Herz, 2002, Volume: 27, Issue:8

    Topics: Aged; Aortic Valve Stenosis; Blood Flow Velocity; Cardiac Volume; Coronary Angiography; Coronary Cir

2002
The comparative value of the aortic atherosclerosis and the coronary flow velocity reserve evaluated by stress transesophageal echocardiography in the prediction of patients with aortic stenosis with coronary artery disease.
    The international journal of cardiovascular imaging, 2003, Volume: 19, Issue:5

    Topics: Aged; Aorta; Aortic Valve Stenosis; Blood Flow Velocity; Coronary Angiography; Coronary Artery Disea

2003
[Effect of tachycardia on hemodynamics and coronary circulation. Different relevance of ventricular tachycardias for healthy persons, coronary patients and patients with left heart hypertrophy].
    Fortschritte der Medizin, 1984, Oct-25, Volume: 102, Issue:40

    Topics: Aortic Valve; Aortic Valve Stenosis; Cardiac Pacing, Artificial; Cardiomegaly; Coronary Circulation;

1984
Dipyridamole-aspirin as thromboembolic prophylaxis in patients with aortic valve prosthesis. Prospective study with the Model 2320 Starr-Edwards prosthesis.
    The Journal of thoracic and cardiovascular surgery, 1981, Volume: 81, Issue:4

    Topics: Adult; Aged; Aortic Valve; Aortic Valve Stenosis; Aspirin; Bioprosthesis; Dipyridamole; Drug Therapy

1981
Computer-assisted evaluation of dipyridamole thallium-201 SPECT in patients with aortic stenosis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994, Volume: 35, Issue:6

    Topics: Adult; Aged; Aortic Valve Stenosis; Coronary Angiography; Coronary Disease; Dipyridamole; Echocardio

1994
Dipyridamole thallium-201 single-photon emission tomography in aortic stenosis: gender differences.
    European journal of nuclear medicine, 1995, Volume: 22, Issue:10

    Topics: Aged; Aortic Valve Stenosis; Case-Control Studies; Coronary Disease; Dipyridamole; Female; Humans; I

1995
Mechanisms of regional ischaemic changes during dipyridamole echocardiography in patients with severe aortic valve stenosis and normal coronary arteries.
    Heart (British Cardiac Society), 1996, Volume: 75, Issue:5

    Topics: Adult; Aged; Aortic Valve; Aortic Valve Stenosis; Coronary Disease; Dipyridamole; Echocardiography;

1996
Preoperative assessment of coronary artery disease in aortic stenosis: a dipyridamole echocardiographic study.
    The Annals of thoracic surgery, 1998, Volume: 65, Issue:2

    Topics: Aortic Valve Stenosis; Blood Pressure; Coronary Disease; Dipyridamole; Echocardiography; Heart Rate;

1998
The safety of dipyridamole-thallium imaging in patients with critical aortic valve stenosis and angina.
    Nuclear medicine communications, 1998, Volume: 19, Issue:8

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Aortic Valve Stenosis; Coronary Angiography; Coronary Dise

1998
[The role of the echo-dipyridamole test in the diagnosis of coronary disease in patients with associated aortic stenosis].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2000, Volume: 1, Issue:1

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Chi-Square Distribution; Coronary Angiography; Coron

2000
Influence of long-term treatment with dipyridamole on the aorta-stenosed rabbit heart: morphometric and functional investigations.
    Cardiovascular research, 1976, Volume: 10, Issue:5

    Topics: Animals; Aortic Valve Stenosis; Blood Pressure; Cardiomegaly; Dipyridamole; Disease Models, Animal;

1976
[Circulatory and metabolic action of pressure-induced cardiac hypertrophy in rest, during exercise and following medicinal dilatation of the coronary vessels].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aortic Valve Stenosis; Cardiomegaly; Coronary Circulation; Dipyridamole; Humans; Lactates; Oxygen; P

1977
Platelet survival time following aortic valve replacement.
    Circulation, 1975, Volume: 51, Issue:2

    Topics: Adult; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Aspirin; Blood Platelets; Ce

1975
Decision analysis in clinical cardiology: when is coronary angiography required in aortic stenosis?
    Journal of the American College of Cardiology, 1990, Mar-15, Volume: 15, Issue:4

    Topics: Angiography; Aortic Valve; Aortic Valve Stenosis; Coronary Angiography; Coronary Disease; Cost-Benef

1990
Detection of coronary artery disease by thallium imaging using a combined intravenous dipyridamole and isometric handgrip test in patients with aortic valve stenosis.
    The American journal of cardiology, 1987, Feb-01, Volume: 59, Issue:4

    Topics: Aged; Aortic Valve Stenosis; Blood Pressure; Coronary Circulation; Coronary Disease; Dipyridamole; F

1987
Valvar aortic stenosis in adults: an update.
    Scottish medical journal, 1986, Volume: 31, Issue:1

    Topics: Adult; Anticoagulants; Aortic Valve Stenosis; Aspirin; Calcinosis; Dipyridamole; Echocardiography; E

1986
[Influence of long-term treatment with dipyridamole on the contractility and development of hypertrophy in rabbit heart with aortic stenois].
    Acta biologica et medica Germanica, 1972, Volume: 28, Issue:5

    Topics: Animals; Aortic Valve Stenosis; Blood Pressure; Body Weight; Cardiomegaly; Dipyridamole; Female; Hea

1972
The influence of hypertrophy and hypoxia on potentiation phenomena of the rabbit papillary muscle tested by a double rest programme.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Animals; Aortic Valve Stenosis; Calcium; Cardiomegaly; Dipyridamole; Electric Stimulation; Heart Ven

1974