Page last updated: 2024-10-26

dipyridamole and Anoxemia

dipyridamole has been researched along with Anoxemia in 86 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
" Twelve healthy young men took part in this investigation of the effect of oral theophylline and dipyridamole (two drugs known to affect the pharmacological effects of the purine nucleoside adenosine) on the respiratory response to isocapnic hypoxia."9.07Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects. ( Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST, 1991)
"Based on the hypothesis that blood platelets contribute to the pathogenesis of hypoxemic pulmonary hypertension in patients with chronic obstructive pulmonary disease (COPD), the effect of a prolonged treatment with dipyridamole, a platelet-inhibiting drug, on hypoxemic pulmonary hypertension was evaluated in a double-blind cross-over study."9.06Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease. ( Berrettini, M; Costantini, V; Nenci, GG; Parise, P; Todisco, T, 1988)
"The effect of hypoxia on the release of adenosine was studied in vitro in the rat whole carotid body (CB) and compared with the effect of hypoxia (2%, 5% and 10% O(2)) on adenosine concentrations in superior cervical ganglia (SCG) and carotid arteries."7.72Hypoxia induces adenosine release from the rat carotid body. ( Conde, SV; Monteiro, EC, 2004)
"Adenosine, a purine nucleoside, plays a variety of roles in cardiovascular and ventilatory control, and may be a marker of tissue hypoxia."7.70Plasma concentration of adenosine during normoxia and moderate hypoxia in humans. ( Kawakami, Y; Makita, H; Miyamoto, K; Nishimura, M; Saito, H; Sato, F; Shibuya, E; Shinano, H; Tsujino, I, 1999)
"We measured the changes in pial arteriolar diameter and CSF concentrations of adenosine, inosine, and hypoxanthine during hypoxia in the absence and presence of topically applied dipyridamole (10(-6) M) and erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA; 10(-5) M)."7.68Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia. ( Meno, JR; Ngai, AC; Winn, HR, 1993)
"The purpose of this study was to determine the effects of acute hypoxia on the ATP content of, and release of adenosine from, cultured endothelial cells."7.67Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. ( Berne, RM; Rubio, R; Shryock, JC, 1988)
"Pretreatment with dipyridamole blunted the increase in Ppa and Rp/Rs during repeat hypoxia, keeping Ppa at a subsystemic level and Rp/Rs < 1."5.30Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. ( Abman, SH; Clarke, WR; Ivy, DD; Kinsella, JP; Wiggins, JW; Ziegler, JW, 1998)
"The purine nucleoside, adenosine, has been implicated as a neuromodulator in central respiratory depression during prolonged exposure to hypoxia."5.08The effect of dipyridamole and theophylline on hypercapnic ventilatory responses: the role of adenosine. ( Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST, 1997)
"To examine the role of endogenous adenosine in hypoxic ventilatory response, we measured, in nine normal young adults, ventilatory responses to isocapnic progressive hypoxia and subsequent sustained hypoxia [arterial O2 saturation (SaO2); 80%, 20 min] with and without pretreatment with dipyridamole in a double-blind crossover fashion."5.07Role of endogenous adenosine in hypoxic ventilatory response in humans: a study with dipyridamole. ( Akiyama, Y; Kawakami, Y; Kobayashi, S; Miyamoto, K; Nishimura, M; Yamamoto, M, 1994)
" Twelve healthy young men took part in this investigation of the effect of oral theophylline and dipyridamole (two drugs known to affect the pharmacological effects of the purine nucleoside adenosine) on the respiratory response to isocapnic hypoxia."5.07Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects. ( Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST, 1991)
"Based on the hypothesis that blood platelets contribute to the pathogenesis of hypoxemic pulmonary hypertension in patients with chronic obstructive pulmonary disease (COPD), the effect of a prolonged treatment with dipyridamole, a platelet-inhibiting drug, on hypoxemic pulmonary hypertension was evaluated in a double-blind cross-over study."5.06Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease. ( Berrettini, M; Costantini, V; Nenci, GG; Parise, P; Todisco, T, 1988)
"Using a rat model of cerebral ischemia, the ENT1 inhibitor nitrobenzylmercaptopurine ribonucleoside (NBMPR) significantly increased post-ischemic forebrain adenosine levels and significantly decreased hippocampal neuron injury relative to saline-treatment."3.73Astrocytes and neurons: different roles in regulating adenosine levels. ( Parkinson, FE; Xiong, W; Zamzow, CR, 2005)
"The effect of hypoxia on the release of adenosine was studied in vitro in the rat whole carotid body (CB) and compared with the effect of hypoxia (2%, 5% and 10% O(2)) on adenosine concentrations in superior cervical ganglia (SCG) and carotid arteries."3.72Hypoxia induces adenosine release from the rat carotid body. ( Conde, SV; Monteiro, EC, 2004)
"Adenosine, a purine nucleoside, plays a variety of roles in cardiovascular and ventilatory control, and may be a marker of tissue hypoxia."3.70Plasma concentration of adenosine during normoxia and moderate hypoxia in humans. ( Kawakami, Y; Makita, H; Miyamoto, K; Nishimura, M; Saito, H; Sato, F; Shibuya, E; Shinano, H; Tsujino, I, 1999)
"The role of intracerebral adenosine levels in the control of ventilatory response to hypoxia was explored in 15 spontaneously breathing intubated piglets, 1-5 days old, sedated with chloral hydrate."3.69Role of adenosine in the hypoxic ventilatory response of the newborn piglet. ( Aranda, JV; Davis, GM; Lopes, JM; Mullahoo, K, 1994)
"In the present study, we have investigated the possible role of adenosine in the hypoxia-mediated increase in adenosine 3',5'-cyclic monophosphate (cAMP) in the carotid body."3.69cAMP production in rabbit carotid body: role of adenosine. ( Chen, J; Dinger, B; Fidone, SJ, 1997)
"We measured the changes in pial arteriolar diameter and CSF concentrations of adenosine, inosine, and hypoxanthine during hypoxia in the absence and presence of topically applied dipyridamole (10(-6) M) and erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA; 10(-5) M)."3.68Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia. ( Meno, JR; Ngai, AC; Winn, HR, 1993)
"The purpose of this study was to determine the effects of acute hypoxia on the ATP content of, and release of adenosine from, cultured endothelial cells."3.67Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. ( Berne, RM; Rubio, R; Shryock, JC, 1988)
"Data are reviewed describing hypoxemia, a newly identified feature in thalassemia."2.38Hypoxemia in thalassemia. ( Bunyaratvej, A; Chantaraksri, U; Fucharoen, S; Piankijagum, A; Siritanaratkul, N; Sonakul, D; Wasi, P; Winichagoon, P, 1992)
"Pretreatment with dipyridamole blunted the increase in Ppa and Rp/Rs during repeat hypoxia, keeping Ppa at a subsystemic level and Rp/Rs < 1."1.30Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. ( Abman, SH; Clarke, WR; Ivy, DD; Kinsella, JP; Wiggins, JW; Ziegler, JW, 1998)
"Treatment with theophylline did not alter the elevation of plasma [ADO] after dipyridamole infusion, but abolished responses of fetal heart rate to dipyridamole infusion."1.28Plasma adenosine and cardiovascular responses to dipyridamole in fetal sheep. ( Power, GG; Yoneyama, Y, 1992)
"Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue."1.27Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia. ( Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS, 1986)
"Dipyridamole did not produce any significant effect on phosphate metabolism in anoxic myocardium."1.26Effects of propranolo, itramin tosylate and dipyridamole on myocardial phosphate metabolism in anoxic perfused rat hearts. ( Takenaka, F; Umeda, T, 1976)
"Although anoxia releases noradrenaline from the heart the effect of anoxia on the VFT was not prevented by beta-adrenoceptor blockade with propranolol or pindolol or by previous treatment with reserpine."1.25The effect of anoxia on the ventricular fibrillation threshold in the rabbit isolated heart. ( Murnaghan, MF, 1975)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199062 (72.09)18.7374
1990's21 (24.42)18.2507
2000's3 (3.49)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shih, WJ1
Li, CY1
Kiefer, V1
NEUHAUS, G1
LERCHE, D1
SCHUCK, P1
FRIMMER, M1
HEGNER, D1
WINKELMANN, W1
BETZ, E1
BENZING, H1
KNOCHE, H1
SCHMITT, G2
CHIBA, T1
LOVE, WD1
TYLER, MD1
ABRAHAM, RE1
MUNFORD, RS1
EKESTROEM, S1
PALEUS, S1
ABERG, T1
Conde, SV1
Monteiro, EC1
Parkinson, FE1
Xiong, W1
Zamzow, CR1
Nenci, GG3
Berrettini, M2
Todisco, T2
Parise, P2
Phillis, JW2
Preston, G1
DeLong, RE1
Fucharoen, S2
Youngchaiyud, P1
Wasi, P2
Donaghy, KM1
Scholfield, CN1
Igarashi, T1
Nishimura, M4
Akiyama, Y2
Yamamoto, M3
Miyamoto, K4
Kawakami, Y4
Kobayashi, S2
Nasuhara, Y1
Lopes, JM1
Davis, GM1
Mullahoo, K1
Aranda, JV1
Ran, PX1
Duan, SF1
Meno, JR1
Ngai, AC1
Winn, HR1
Hofer, M1
Pospísil, M1
Netíková, J1
Znojil, V1
Vácha, J1
Holá, J1
Griffiths, TL2
Christie, JM2
Parsons, ST2
Holgate, ST2
Chen, J1
Dinger, B1
Fidone, SJ1
Gleiter, CH2
Brause, M1
Delabar, U1
Zebski, H1
Eckardt, KU1
Becker, T1
Wenzel, J1
Ziegler, JW1
Ivy, DD1
Wiggins, JW1
Kinsella, JP1
Clarke, WR1
Abman, SH1
Saito, H1
Shinano, H1
Makita, H1
Tsujino, I1
Shibuya, E1
Sato, F1
Takenaka, F1
Umeda, T1
Degenring, FH1
Curnish, RR1
Rubio, R2
Berne, RM3
Heckeroth, VA1
Michel, CF1
Benzi, G2
Mlczoch, J1
Weir, EK1
Grover, RF1
Coeugniet, E1
Murnaghan, MF1
Luque, J1
Pinilla, M1
Monfort, R2
Aznar, J1
Alemany, JR1
Winichagoon, P1
Siritanaratkul, N1
Sonakul, D1
Chantaraksri, U1
Bunyaratvej, A1
Piankijagum, A1
Yoneyama, Y1
Power, GG1
O'Regan, MH1
Perkins, LM1
Froldi, G1
Belardinelli, L2
Milusheva, E1
Sperlágh, B1
Kiss, B1
Szporny, L1
Pásztor, E1
Papasova, M1
Vizi, ES1
Keith, IM1
Will, JA1
Huxtable, RJ1
Weir, K1
Barrett, JA1
DePaul Lynch, V1
Balkon, J1
Smith, RD1
Wolf, PS1
Watanabe, K1
Kimura, Y1
Abiko, Y3
Shryock, JC1
Decking, UK1
Juengling, E1
Kammermeier, H1
Costantini, V1
McIlwain, H1
Poll, JD1
Arrigoni, E1
Manzo, L1
De Bernardi, M1
Ferrara, A1
Panceri, P1
Berte, F1
Virtanen, KS1
Meisel, M1
Meisel, P1
Urbaszek, W1
Tronicke, E1
Modersohn, D1
Uhlich, C1
Günther, K1
Pankau, H1
Duchène-Marullaz, P1
Cosnier, D1
Perriere, JP1
Hache, J1
Juhran, W1
Voss, EM1
Dietmann, K1
Schaumann, W1
Swan, H1
Meagher, DM1
Wussling, M1
Szymanski, G1
Schrör, K1
Minamidate, A1
Takano, S2
Hashikawa, T2
Hayashi, A1
Haas, H1
Gokel, M1
Wadsworth, RM2
Matthys, H2
Rühle, KH2
Schilling, M2
Freitag, M2
Konietzko, N2
Schlehe, H2
Kleeberg, UR2
Parratt, JR1
Merchant, FJ1
Feinberg, H1
Levitsky, S1
Schoen, HR1
Gerlach, E1
Deuticke, B1
Rosenkrantz, JG2
Lynch, FP2
Vogel, JH2
Kukovetz, WR1
Pöch, G1
Bassenge, E1
Walter, P1
Doutheil, U1
Doll, E1
Keul, J1
Lemieux, VP1
Gowdey, CW1
Philp, RB1
Gutiérrez Goicoechea, JM1
Hauss, W1
Kontos, HA1
Goldin, D1
Richardson, DW1
Patterson, JL1
Diesfeld, HJ1
López-Campos, JL1
Vega Cid, J1
Rosa, LM1
Kusukawa, R1
MacCanon, DM1
Kisch, B1
Kraupp, O1
Keegan, DJ1
Webster, I1
Belmonte, A1
Lozada, BB1
Laguens, RP1

Reviews

5 reviews available for dipyridamole and Anoxemia

ArticleYear
[ON CHEMO- AND PRESSOR RECEPTOR FIELDS IN THE CORONARY CIRCULATION].
    Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948), 1963, Dec-03, Volume: 61

    Topics: Anemia; Animals; Cats; Child; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs; Electrons;

1963
A case of pulmonary AV fistula. Possible involvement of adenosine in hyperventilation.
    American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:6 Pt 1

    Topics: Adenosine; Adult; Aminophylline; Arteriovenous Fistula; Combined Modality Therapy; Dipyridamole; Hum

1994
Hypoxemia in thalassemia.
    The Southeast Asian journal of tropical medicine and public health, 1992, Volume: 23 Suppl 2

    Topics: Aspirin; Blood Gas Analysis; Dipyridamole; Follow-Up Studies; Heart Failure; Humans; Hypoxia; Platel

1992
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
    Die Pharmazie, 1974, Volume: 29, Issue:9

    Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide;

1974
[Comparative animal experiment studies of the prolongation of the revival time of the heart and the whole organ in normothermia by pharmacological pretreatment].
    Archiv fur Kreislaufforschung, 1968, Volume: 57, Issue:1

    Topics: Adenine Nucleotides; Anesthesia, General; Animals; Cardiac Surgical Procedures; Chromatography, Pape

1968

Trials

8 trials available for dipyridamole and Anoxemia

ArticleYear
Enhanced plasma beta-thromboglobulin in hypoxemia: effect of dipyridamole.
    The New England journal of medicine, 1981, Apr-23, Volume: 304, Issue:17

    Topics: Aged; Beta-Globulins; beta-Thromboglobulin; Clinical Trials as Topic; Dipyridamole; Female; Humans;

1981
Effect of aminophylline on plasma [K+] and hypoxic ventilatory response during mild exercise in men.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:4

    Topics: Adolescent; Adult; Aminophylline; Catecholamines; Chromatography, High Pressure Liquid; Dipyridamole

1994
Role of endogenous adenosine in hypoxic ventilatory response in humans: a study with dipyridamole.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:1

    Topics: Adenosine; Adult; Carbon Dioxide; Dipyridamole; Double-Blind Method; Humans; Hypoxia; Infusions, Int

1994
The effect of dipyridamole and theophylline on hypercapnic ventilatory responses: the role of adenosine.
    The European respiratory journal, 1997, Volume: 10, Issue:1

    Topics: Adenosine; Administration, Oral; Adult; Analysis of Variance; Bronchodilator Agents; Carbon Dioxide;

1997
Erythropoietin production in healthy volunteers subjected to controlled hypobaric hypoxia: further evidence against a role for adenosine.
    British journal of clinical pharmacology, 1997, Volume: 44, Issue:2

    Topics: Adenosine; Adult; Area Under Curve; Atmosphere Exposure Chambers; Dipyridamole; Erythropoietin; Huma

1997
[Mechanism of ventilatory and heart-rate responses during sustained hypoxia in humans--role of endogenous adenosine].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1997, Volume: 72, Issue:6

    Topics: Adenosine; Adult; Cross-Over Studies; Dipyridamole; Double-Blind Method; Heart Rate; Humans; Hypoxia

1997
Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects.
    Clinical science (London, England : 1979), 1991, Volume: 80, Issue:2

    Topics: Adenosine; Adult; Carbon Dioxide; Computers; Dipyridamole; Double-Blind Method; Humans; Hypoxia; Mal

1991
Effects of dipyridamole on the hypoxemic pulmonary hypertension of patients with chronic obstructive pulmonary disease.
    Respiration; international review of thoracic diseases, 1988, Volume: 53, Issue:1

    Topics: Aged; Blood Pressure; Dipyridamole; Humans; Hypertension, Pulmonary; Hypoxia; Lung Diseases, Obstruc

1988

Other Studies

73 other studies available for dipyridamole and Anoxemia

ArticleYear
Significance of the visualization of bone marrow during dipyridamole Tc-99m tetrofosmin myocardial and gated SPECT.
    Clinical nuclear medicine, 2002, Volume: 27, Issue:11

    Topics: Aged; Anemia; Bone Marrow; Chest Pain; Dipyridamole; Emphysema; Female; Gated Blood-Pool Imaging; He

2002
[The hypoxia test in evaluation of coronary-active drugs, especially of persantin in man].
    Medizinische Klinik, 1961, Apr-14, Volume: 56

    Topics: Cardiovascular Agents; Coronary Vessels; Dipyridamole; Hypoxia; Vasodilator Agents

1961
[The effect of 2,6-bis (diethanolamino)-4,8-dipiperidino-pyrimido-(5,4-d)-pyrimidine (Persantin) on the respiration of mitochondria in low O2 pressure].
    Klinische Wochenschrift, 1963, Jul-15, Volume: 41

    Topics: Cell Respiration; Dipyridamole; Electron Transport Complex II; Humans; Hypoxia; Liver; Metabolism; M

1963
[ON THE MECHANISM OF ACTION OF 2,6-BIS(DIETHANOLAMINO)-4,8-DIPIPERIDINOPYRIMIDO(5,4-D)PYRIMIDINE ON MYOCARDIAL CIRCULATION].
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Blood Circulation; Cats; Dipyridamole; Hypoxia; Muscles; Myocardium; Pharmacology; Pyrimidines; Rese

1963
EXPERIMENTAL STUDIES ON THE EFFECTS OF PERSANTIN WITH NORMAL AND GO-DOGS.
    Bulletin of the Osaka Medical School, 1963, Volume: 9

    Topics: Coronary Disease; Dipyridamole; Dogs; Hypoxia; Pathology; Pharmacology; Research

1963
EFFECTS OF O2,CO2, AND DRUGS ON ESTIMATING CORONARY BLOOD FLOW FROM RB86 CLEARANCE.
    The American journal of physiology, 1965, Volume: 208

    Topics: Animals; Blood Circulation; Blood Gas Analysis; Carbon Dioxide; Coronary Vessels; Digitoxin; Dipyrid

1965
[BIOCHEMICAL AND PHYSIOLOGIC STUDIES ON THE ANOXIC DOG HEART WITH EXTRACORPOREAL CIRCULATION WITH AND WITHOUT ADMINISTRATION OF PERSANTIN (2,6-BIS(DIETHANOLAMINO)-4,8-DIPIPERIDINO-PYRIMIDO-(5,4-D)PYRIDINE)].
    Cardiologia, 1965, Volume: 46

    Topics: Adenosine Triphosphate; Blood; Dipyridamole; Dogs; Extracorporeal Circulation; Heart; Heart Function

1965
Hypoxia induces adenosine release from the rat carotid body.
    Journal of neurochemistry, 2004, Volume: 89, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Carotid Body; Carrier Proteins; Chemorec

2004
Astrocytes and neurons: different roles in regulating adenosine levels.
    Neurological research, 2005, Volume: 27, Issue:2

    Topics: Adenosine; Affinity Labels; Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Deoxyglucose; Dipy

2005
Platelets, hypoxemia and pulmonary hypertension.
    Advances in experimental medicine and biology, 1984, Volume: 164

    Topics: Blood Platelets; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Humans; Hypertension, Pulmon

1984
Effects of anoxia on cerebral blood flow in the rat brain: evidence for a role of adenosine in autoregulation.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1984, Volume: 4, Issue:4

    Topics: Adenosine; Animals; Brain; Caffeine; Cerebrovascular Circulation; Dipyridamole; Homeostasis; Hypoxia

1984
Hypoxaemia and the effect of aspirin in thalassaemia.
    The Southeast Asian journal of tropical medicine and public health, 1981, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aspirin; Dipyridamole; Female; Humans; Hypoxia; Male; Middle Aged; Splenectomy; T

1981
Concentration dependence of adenosine and the protection of rat cortical neurones during anoxia.
    Brain research, 1994, Sep-05, Volume: 656, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Animals; Dipyridamole; Evoked Potentials; Hypoxia; In Vitro Techniqu

1994
Role of adenosine in the hypoxic ventilatory response of the newborn piglet.
    Pediatric pulmonology, 1994, Volume: 17, Issue:1

    Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Cerebrospinal Fluid; Citrates; Dipyridamole; Drug Co

1994
[The effects of persantine on pulmonary arterial pressure of rats exposed to hypoxia].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1993, Volume: 16, Issue:4

    Topics: Animals; Blood Pressure; Dipyridamole; Hypertension, Pulmonary; Hypoxia; Male; Rats; Rats, Sprague-D

1993
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:2

    Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hy

1993
Radioprotective efficacy of dipyridamole and AMP combination in fractionated radiation regimen, and its dependence on the time of administration of the drugs prior to irradiation.
    Physiological research, 1995, Volume: 44, Issue:2

    Topics: Adenosine Monophosphate; Animals; Body Weight; Cell Division; Dipyridamole; Drug Administration Sche

1995
cAMP production in rabbit carotid body: role of adenosine.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 82, Issue:6

    Topics: Adenosine; Animals; Carotid Body; Cyclic AMP; Dipyridamole; Hypoxia; In Vitro Techniques; Phenethyla

1997
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
    Kidney international, 1997, Volume: 52, Issue:2

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyri

1997
Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:5 Pt 1

    Topics: Administration, Inhalation; Adolescent; Adult; Aorta; Blood Pressure; Bronchodilator Agents; Cardiac

1998
Plasma concentration of adenosine during normoxia and moderate hypoxia in humans.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:3

    Topics: Adenosine; Arteries; Chromatography, High Pressure Liquid; Dipyridamole; Humans; Hypoxia; Male; Oxyg

1999
Effects of propranolo, itramin tosylate and dipyridamole on myocardial phosphate metabolism in anoxic perfused rat hearts.
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 222, Issue:1

    Topics: Adrenergic beta-Antagonists; Anaerobiosis; Animals; Dipyridamole; Ethylamines; Heart; Heart Rate; Hy

1976
Effect of dipyridamole on myocardial adenosine metabolism and coronary flow in hypoxia and reactive hyperemia in the isolated perfused guinea pig heart.
    Journal of molecular and cellular cardiology, 1976, Volume: 8, Issue:11

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiome

1976
[The effect of various substances on the time of survival of rabbits under conditiones of oxygen-delay (author's transl)].
    Archiv fur Gynakologie, 1977, Mar-31, Volume: 222, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis; Actihaemyl; Animals; Asphyxia; Blood Gas Analysis; Dipyridamole; Fe

1977
An analysis of the drugs acting on cerebral energy metabolism.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:3

    Topics: Adenine Nucleotides; Amobarbital; Animals; Bemegride; Brain; Dipyridamole; Dogs; Energy Metabolism;

1975
Inhibition of hypoxic pulmonary vasoconstriction by dipyridamole is not platelet mediated.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3

    Topics: Animals; Blood Platelets; Blood Pressure; Dipyridamole; Dogs; Female; Hypoxia; Immune Sera; Lung; Ma

1977
Drugs with antithrombotic effect: experimental study.
    Thrombosis and haemostasis, 1976, Apr-30, Volume: 35, Issue:2

    Topics: Animals; Aspirin; Dipyridamole; Drug Synergism; Heparin; Hypoxia; Lysine; Mice; Platelet Aggregation

1976
The effect of anoxia on the ventricular fibrillation threshold in the rabbit isolated heart.
    British journal of pharmacology, 1975, Volume: 54, Issue:4

    Topics: Adenosine; Animals; Dipyridamole; Electrocardiography; Heart; Heart Rate; Hypoxia; In Vitro Techniqu

1975
In vivo influence of dipyridamole and KCN on 2,3-diphosphoglycerate levels in hamsters.
    Archivos de farmacologia y toxicologia, 1976, Volume: 2, Issue:1

    Topics: Animals; Cricetinae; Cyanates; Diphosphoglyceric Acids; Dipyridamole; Erythrocytes; Hypoxia; Injecti

1976
Plasma adenosine and cardiovascular responses to dipyridamole in fetal sheep.
    Journal of developmental physiology, 1992, Volume: 18, Issue:5

    Topics: Adenosine; Animals; Blood Pressure; Dipyridamole; Female; Fetus; Gestational Age; Heart Rate, Fetal;

1992
Measurement of rat plasma adenosine levels during normoxia and hypoxia.
    Life sciences, 1992, Volume: 51, Issue:15

    Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Blood Pressure; Carbon Dioxide; Chromatography

1992
Species-dependent effects of adenosine on heart rate and atrioventricular nodal conduction. Mechanism and physiological implications.
    Circulation research, 1990, Volume: 67, Issue:4

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Atrioventricular Node; Bundle of His; D

1990
Inhibitory effect of hypoxic condition on acetylcholine release is partly due to the effect of adenosine released from the tissue.
    Brain research bulletin, 1990, Volume: 24, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Dipyridamole; Female; Guinea Pigs; Hypoxia; In Vitro Techniques;

1990
Anti-platelet agents reduce morphological changes of chronic hypoxic pulmonary hypertension.
    Histology and histopathology, 1987, Volume: 2, Issue:2

    Topics: Animals; Dipyridamole; Flunarizine; Heart; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Male;

1987
Effects of hypoxia and ischaemia on coronary vascular resistance, A-V node conduction and S-A node excitation.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 694

    Topics: Adenine Nucleotides; Adenosine; Aminophylline; Atrioventricular Node; Coronary Circulation; Coronary

1985
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
    Pharmacology, 1986, Volume: 33, Issue:3

    Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dog

1986
Nifedipine increases oxygen saturation level of myoglobin in the rat heart during hypoxia.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:2

    Topics: Animals; Dipyridamole; Heart; Hypoxia; Male; Myocardium; Myoglobin; Nifedipine; Nitroglycerin; Rats;

1986
Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition.
    The American journal of physiology, 1988, Volume: 254, Issue:2 Pt 2

    Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Cells, Cultured; Dipyridamole; Endothelium, Vascu

1988
Interstitial transudate concentration of adenosine and inosine in rat and guinea pig hearts.
    The American journal of physiology, 1988, Volume: 254, Issue:6 Pt 2

    Topics: Adenosine; Animals; Coformycin; Coronary Circulation; Dipyridamole; Exudates and Transudates; Guinea

1988
Adenosine in cerebral homeostatic role: appraisal through actions of homocysteine, colchicine, and dipyridamole.
    Journal of neurobiology, 1986, Volume: 17, Issue:1

    Topics: Adenine; Adenosine; Animals; Cerebral Cortex; Colchicine; Dipyridamole; Glutamates; Guinea Pigs; Hom

1986
Estimation of changes induced by drugs in cerebral energy-coupling processes in situ in the dog.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:5

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Anesthesia; Animals; Bemegride; Brain; Bromine

1973
Phasic myocardial blood content. An experimental study on effects of hypoxaemia, ischaemia and coronary drugs.
    Annals of clinical research, 1974, Volume: 6, Issue:0

    Topics: Animals; Anti-Arrhythmia Agents; Biopsy; Cardiac Output; Chromium Radioisotopes; Coronary Circulatio

1974
[Effects of coronary vaso dilators on myocardial survival time in the rat under anoxia conditions].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Jul-01, Volume: 29, Issue:13

    Topics: Animals; Coronary Circulation; Dipyridamole; Female; Heart; Hypoxia; Male; Myocardium; Nitroglycerin

1974
[Tentative evaluation of the antianoxic capiacity of dipyridamole and piridoxilate].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1968, Volume: 162, Issue:2

    Topics: Anesthesia, General; Animals; Cyanides; Dipyridamole; Dogs; Glycolates; Guinea Pigs; Hypoxia

1968
Pharmacological effects on coronary reactive hyperemia in conscious dogs.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 269, Issue:1

    Topics: Animals; Coronary Disease; Coronary Vessels; Coumarins; Dipyridamole; Dogs; Drug Synergism; Glycolat

1971
Total body bypass in miniature pigs. Postperfusion pulmonary hypertension.
    The Journal of thoracic and cardiovascular surgery, 1971, Volume: 61, Issue:6

    Topics: Acidosis; Anesthesia, Inhalation; Animals; Blood Group Incompatibility; Blood Pressure; Capillary Pe

1971
The influence of hypertrophy and hypoxia on potentiation phenomena of the rabbit papillary muscle tested by a double rest programme.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Animals; Aortic Valve Stenosis; Calcium; Cardiomegaly; Dipyridamole; Electric Stimulation; Heart Ven

1974
Transmural gradient of NAD-NADPH ratio in their canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:1

    Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; Myocardium;

1973
Redox state of nicotinamide-adenine dinucleotide in the inner and outer layers of canine left ventricle, and effects of coronary dilators on the redox state.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:5

    Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Female; Heart Ventricles; Hypoxia; Male; NAD; Nitrogl

1974
[Effect of Verapamil on the metabolism of myocardium].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:5

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Asphyxia; Blood Glucos

1970
Anti-anginal drugs and the vasodilator response to myocardial hypoxia.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23

    Topics: Angina Pectoris; Animals; Cats; Collateral Circulation; Coronary Circulation; Dipyridamole; Drug Syn

1971
[Proceedings: Effect of dipyridamole and acute hypoxia on oxygen-binding capacity of hemoglobin in normal persons].
    Helvetica medica acta, 1974, Volume: 37, Issue:5-6

    Topics: Blood Pressure; Cardiac Volume; Dipyridamole; Hemoglobins; Humans; Hypoxia; Lung; Oxygen Consumption

1974
The effects of dipyridamole on coronary post-occlusion hyperaemia and on myocardial vasodilatation induced by systemic hypoxia.
    British journal of pharmacology, 1972, Volume: 46, Issue:4

    Topics: Animals; Benzoates; Blood Pressure; Catheterization; Cats; Coronary Vessels; Dipyridamole; Electroca

1972
Reversal of myocardial depression by dipyridamole following aortic cross-clamping.
    Surgical forum, 1972, Volume: 23, Issue:0

    Topics: Animals; Aorta; Depression, Chemical; Dipyridamole; Dogs; Heart; Heart Arrest; Hypoxia

1972
Adaptation of the oxygen affinity of haemoglobin in acute hypoxia.
    European journal of clinical investigation, 1974, Volume: 4, Issue:1

    Topics: Adaptation, Biological; Adolescent; Adult; Dipyridamole; Hemoglobins; Humans; Hydrogen-Ion Concentra

1974
[Comparative studies on the formation of adenosine in the myocardium of different animal species in oxygen deficiency].
    Klinische Wochenschrift, 1966, Nov-15, Volume: 44, Issue:22

    Topics: Adenine Nucleotides; Aminohydrolases; Animals; Cats; Dipyridamole; Dogs; Guinea Pigs; Haplorhini; He

1966
Hypoxic pulmonary hypertension: its modification by dipyridamole.
    The Journal of surgical research, 1972, Volume: 12, Issue:5

    Topics: Animals; Blood Pressure; Cardiac Catheterization; Cardiac Output; Dipyridamole; Hemodynamics; Hypert

1972
Inhibition of hypoxia-induced rise in adenosine release and flow by coronary dilators.
    Cardiology, 1971, Volume: 56, Issue:1

    Topics: Adenosine; Animals; Carbon Isotopes; Coronary Circulation; Coronary Vessels; Dipyridamole; Guinea Pi

1971
[Reversal of the effect of the adrenergic coronary vascular reaction in dependence upon the coronary vascular tonus].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1967, Volume: 297, Issue:3

    Topics: Animals; Blood Flow Velocity; Coronary Vessels; Dipyridamole; Dogs; Epinephrine; Hypoxia; Isoprotere

1967
[Coronary reserve in man].
    Deutsche medizinische Wochenschrift (1946), 1969, Dec-05, Volume: 94, Issue:49

    Topics: Carbon Dioxide; Coronary Vessels; Dipyridamole; Heart; Hemodynamics; Humans; Hydrogen-Ion Concentrat

1969
Pulmonary hypertension: treatment by drugs which modify intravascular aggregation.
    Surgical forum, 1969, Volume: 20

    Topics: Animals; Blood Platelets; Dipyridamole; Hypertension, Pulmonary; Hypoxia; Swine

1969
Effects of dipyridamole and nitroprusside on the oxygen paradox and reactive hyperemia.
    Aerospace medicine, 1970, Volume: 41, Issue:2

    Topics: Animals; Blood Pressure; Carotid Arteries; Cats; Dipyridamole; Femoral Artery; Ferricyanides; Hypere

1970
[Resistance of the myocardium in anoxia].
    Revista espanola de anestesiologia y reanimacion, 1971, Volume: 18, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Dipyridamole; Dogs; Electrocardiography; Ethyl Ethers; Halothane; H

1971
[On the protective action of coronary vessel collaterals].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:8

    Topics: Animals; Arteries; Collateral Circulation; Coronary Vessels; Dipyridamole; Hypertension; Hypoxia; Ra

1967
Effect of dipyridamole on vasodilator responses to ischemia, hypoxia, ATP, and AMP.
    The American journal of physiology, 1968, Volume: 214, Issue:1

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Blood Vessels; Dipyridamole; D

1968
[Prophylaxis and therapy of altitude adaptation disturbances with Persantin].
    Therapie der Gegenwart, 1968, Volume: 107, Issue:9

    Topics: Altitude; Dipyridamole; Humans; Hypoxia

1968
[Changes of ATP-ase activity in the heart muscle of the rat in anoxia conditions].
    Revista clinica espanola, 1968, Sep-15, Volume: 110, Issue:5

    Topics: Adenosine Triphosphate; Animals; Dipyridamole; Heart; Hypoxia; Myocardium; Rats

1968
Myocardial tolerance to discontinous hypoxia in guinea pigs.
    Experimental medicine and surgery, 1965, Volume: 23, Issue:2

    Topics: Animals; Coronary Disease; Dipyridamole; Electrocardiography; Guinea Pigs; Hypoxia; In Vitro Techniq

1965
Testing the sarcosome protecting power of certain drugs.
    Experimental medicine and surgery, 1965, Volume: 23, Issue:4

    Topics: Animals; Digitoxin; Dipyridamole; Heart Diseases; Hypoxia; Mitochondria; Mitochondria, Muscle; Oxyge

1965
[Pharmacotherapy of states of deficient myocardial circulation. Pharmacologic aspects].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1965, Volume: 46, Issue:10

    Topics: Anti-Arrhythmia Agents; Dipyridamole; Humans; Hypoxia; Myocardium; Papaverine; Phenobarbital; Vasodi

1965
Preliminary experiments on the effect of Persantin on the animal heart.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1966, May-21, Volume: 40, Issue:19

    Topics: Animals; Cats; Coronary Vessels; Dipyridamole; Electrocardiography; Guinea Pigs; Heart; Heart Functi

1966
[Pharmacological protection against hypercapnic anoxemic anoxia caused by experimental submersion. The role of dipyridamole and of glucose].
    Revista espanola de fisiologia, 1966, Volume: 22, Issue:2

    Topics: Animals; Dipyridamole; Diving; Glucose; Heart; Hypoxia; Mice

1966
Hypoxia and the heart ultrastructure with special reference to the protective action of the coronary drug Persantin.
    Cardiologia, 1966, Volume: 49

    Topics: Animals; Coronary Vessels; Dipyridamole; Dogs; Hypoxia; Microscopy, Electron; Mitochondria; Myocardi

1966