Page last updated: 2024-10-26

dipyridamole and Angina at Rest

dipyridamole has been researched along with Angina at Rest in 41 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"We assessed the safety of early (2 to 4 days) intravenous dipyridamole infusion in conjunction with technetium 99m sestamibi tomographic myocardial perfusion imaging in patients with first myocardial infarction (MI)."9.08Safety of early intravenous dipyridamole technetium 99m sestamibi SPECT myocardial perfusion imaging after uncomplicated first myocardial infarction. Early Post MI IV Dipyridamole Study (EPIDS). ( Brown, KA; Haber, SB; Heller, GV; Landin, RJ, 1997)
"Dipyridamole-thallium SPECT is safely performed and is useful and important for risk stratification in the long-term follow-up of patients with Kawasaki disease."7.70Prognostic value of dipyridamole-thallium myocardial scintigraphy in patients with Kawasaki disease. ( Hamamoto, K; Ikezoe, J; Matsumoto, S; Miyagawa, M; Mochizuki, T; Murase, K; Niino, M; Sekiya, M; Tanada, S, 1998)
"We assessed the safety of early (2 to 4 days) intravenous dipyridamole infusion in conjunction with technetium 99m sestamibi tomographic myocardial perfusion imaging in patients with first myocardial infarction (MI)."5.08Safety of early intravenous dipyridamole technetium 99m sestamibi SPECT myocardial perfusion imaging after uncomplicated first myocardial infarction. Early Post MI IV Dipyridamole Study (EPIDS). ( Brown, KA; Haber, SB; Heller, GV; Landin, RJ, 1997)
"The aim of the study was to evaluate the prognostic value of Doppler echocardiographic-derived coronary flow reserve (CFR) over regional wall motion in patients with known or suspected coronary artery disease (CAD) undergoing dipyridamole echocardiography test (DET)."3.74The additive prognostic value of wall motion abnormalities and coronary flow reserve during dipyridamole stress echo. ( Cortigiani, L; Djordjevic-Dikic, A; Gherardi, S; Picano, E; Rigo, F; Sicari, R, 2008)
"Among patients with medically stabilized unstable angina and a negative dipyridamole stress echocardiogram, male gender and previous myocardial infarction are associated with a non-favourable outcome."3.72Identifying patients without favourable long-term outcome among those with medically stabilized unstable angina and a negative dipyridamole stress echocardiogram. ( Almería, C; Macaya, C; Mataix, L; Moreno, R; Perez de Isla, L; Pérez-González, JA; Rodrigo, JL; Villate, A; Zamorano, J, 2004)
"Dipyridamole-thallium SPECT is safely performed and is useful and important for risk stratification in the long-term follow-up of patients with Kawasaki disease."3.70Prognostic value of dipyridamole-thallium myocardial scintigraphy in patients with Kawasaki disease. ( Hamamoto, K; Ikezoe, J; Matsumoto, S; Miyagawa, M; Mochizuki, T; Murase, K; Niino, M; Sekiya, M; Tanada, S, 1998)
"We evaluate 1,271 patients from the Thrombolysis in Myocardial Infarction (TIMI)-IIIB trial (86% of TIMI-IIIB cohort) with unstable angina or non-Q wave myocardial infarction, who underwent predischarge exercise (92%) or dipyridamole stress (8%) Tl-201 imaging."3.69Relevance of increased lung thallium uptake on stress imaging in patients with unstable angina and non-Q wave myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI)-IIIB Study. ( Jain, D; Thompson, B; Wackers, FJ; Zaret, BL, 1997)
"A case of cardiac arrest and subsequent acute myocardial infarction occurring during thallium-201 imaging with oral dipyridamole augmentation is presented."3.67Cardiac arrest during dipyridamole imaging. ( Blumenthal, MS; McCauley, CS, 1988)
"In 41 patients with a history of an acute myocardial infarction, the location of myocardial ischemia was studied by 201Tl emission computed tomography immediately and 3 h after intravenous dipyridamole."3.67[Localization and quantification of ischemic myocardial areas in the postinfarct phase by dipyridamole 201thallium emission computerized tomography]. ( Bleifeld, W; Clausen, A; Montz, R; Nienaber, CA; Salge, D; Spielmann, RP, 1986)
"Dipyridamole was applied in 550 interventions (455 interventions in men, 95 interventions in women, age = 59."2.68[Intracoronary dipyridamole reduces the incidence of acute coronary vessel occlusion in percutaneous transluminal coronary angioplasty--a prospective randomized study]. ( Heidland, UE; Heintzen, MP; Kelm, M; Klimek, WJ; Leschke, M; Michel, CJ; Schwartzkopff, B; Strauer, BE; Vester, EG, 1997)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199015 (36.59)18.7374
1990's15 (36.59)18.2507
2000's10 (24.39)29.6817
2010's1 (2.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferreira-González, L1
Trigás-Ferrín, M1
Rubin, EP1
Sesma, P1
Kopp, CW1
Steiner, S1
Priglinger, U1
Christ, G1
Probst, P1
Maurer, G1
Minar, E1
Huber, K1
Picano, E3
Sicari, R2
Moreno, R1
Villate, A1
Zamorano, J1
Almería, C1
Pérez-González, JA1
Rodrigo, JL1
Perez de Isla, L1
Mataix, L1
Macaya, C1
Gawaz, M1
Müller, I1
Besta, F1
Petix, NR1
Sestini, S1
Coppola, A1
Marcucci, G1
Nassi, F1
Taiti, A1
Guarnaccia, V1
Mennuti, A1
Mazzoni, V1
Zipoli, A1
Ascione, L1
De Michele, M1
Accadia, M1
Granata, G1
Sacra, C1
D'Andrea, A1
Guarini, P1
Tuccillo, B1
Rigo, F1
Gherardi, S1
Djordjevic-Dikic, A1
Cortigiani, L2
Nielsen, AA1
Veien, KT1
Jørgensen, LG1
Buck, TC1
Brandslund, I1
Christensen, C1
Hillis, LD1
Hayashi, H1
Kisamori, K1
Kaneko, M1
Masumura, Y1
Kamikawa, T1
Kobayashi, A1
Suzuki, Y1
Yamazaki, N1
Yamaguchi, T1
Harada, Y1
Stratmann, HG2
Tamesis, BR1
Younis, LT3
Wittry, MD2
Amato, M2
Miller, DD2
D'Angelo, M1
Simonelli, P1
Del Mastro, L1
Auriemma, F1
Abate, R1
Vetrano, A1
Verheugt, FW1
Brown, KA2
Rowen, M1
Altman, R1
Rouvier, J1
Gurfinkel, E1
Mark, AL1
de Virgilio, C1
Pak, S1
Arnell, T1
Donayre, C1
Lewis, RJ1
Stabile, BE1
White, R1
Jain, D1
Thompson, B1
Wackers, FJ1
Zaret, BL1
Travin, MI1
Duca, MD1
Kline, GM1
Herman, SD1
Demus, DD1
Heller, GV2
Landin, RJ1
Haber, SB1
Heintzen, MP2
Heidland, UE2
Klimek, WJ1
Michel, CJ2
Kelm, M1
Leschke, M1
Schwartzkopff, B1
Vester, EG1
Strauer, BE2
Misumi, I1
Kimura, Y1
Hokamura, Y1
Yamabe, H1
Ueno, K1
Miyagawa, M1
Mochizuki, T1
Murase, K1
Tanada, S1
Ikezoe, J1
Sekiya, M1
Hamamoto, K1
Matsumoto, S1
Niino, M1
Gigli, G1
Vallebona, A1
Orlandi, S1
Mariani, PR1
Volterrani, C1
Zhu, YY1
Chung, WS1
Botvinick, EH1
Dae, MW1
Lim, AD1
Ports, TA1
Danforth, JW1
Wolfe, CL1
Goldschlager, N1
Chatterjee, K1
Charvát, J2
Fiserová, J1
Kuruvilla, T1
Byers, S1
Shaw, L1
Barth, G1
Goodgold, H1
Chaitman, BR1
Borhani, NO1
Keltz, TN1
Innerfield, M1
Gitler, B1
Cooper, JA1
Cairns, JA1
Blumenthal, MS1
McCauley, CS1
Nienaber, CA1
Spielmann, RP1
Salge, D1
Clausen, A1
Montz, R1
Bleifeld, W1
Resnekov, L1
Chediak, J1
Hirsh, J1
Lewis, D1
Patrono, C1
Furkalo, NK1
Simorot, VN1
Lutaĭ, MI1
Voronkov, LG1
Belonozhko, AG1
Beller, GA1
Watson, DD1
Gibson, RS1
Marraccini, P1
Lattanzi, F1
Levantesi, D1
Masini, M1
Dalle Vacche, M1
Distante, A1
L'Abbate, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000472]Phase 30 participants Interventional1989-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for dipyridamole and Angina at Rest

ArticleYear
Combined antithrombotic therapy for acute coronary syndrome.
    Seminars in vascular medicine, 2003, Volume: 3, Issue:2

    Topics: Administration, Oral; Angina, Unstable; Anticoagulants; Aspirin; Clopidogrel; Coronary Thrombosis; D

2003
Percutaneous transluminal coronary angioplasty.
    The American journal of the medical sciences, 1984, Volume: 288, Issue:2

    Topics: Angina, Unstable; Angioplasty, Balloon; Animals; Aspirin; Calcium Channel Blockers; Coronary Artery

1984
[Blood platelet aggregation inhibitors in the treatment of heart diseases].
    Nederlands tijdschrift voor geneeskunde, 1993, Aug-14, Volume: 137, Issue:33

    Topics: Angina, Unstable; Aspirin; Coronary Artery Disease; Coronary Disease; Dipyridamole; Humans; Platelet

1993
Oral anticoagulant treatment with and without aspirin.
    Thrombosis and haemostasis, 1995, Volume: 74, Issue:1

    Topics: Administration, Oral; Angina, Unstable; Anticoagulants; Aspirin; Clinical Trials as Topic; Dipyridam

1995
Clinical trials of antiplatelet drug therapy in acute myocardial infarction, unstable angina, and aortocoronary bypass surgery.
    Cardiovascular clinics, 1987, Volume: 18, Issue:1

    Topics: Angina Pectoris; Angina, Unstable; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Arte

1987
Antithrombotic agents in coronary artery disease.
    Chest, 1986, Volume: 89, Issue:2 Suppl

    Topics: Angina, Unstable; Anticoagulants; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Disea

1986
Aspirin for the prevention of coronary thrombosis: current facts and perspectives.
    European heart journal, 1986, Volume: 7, Issue:6

    Topics: Angina, Unstable; Animals; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disea

1986

Trials

10 trials available for dipyridamole and Angina at Rest

ArticleYear
Parameters of the tissue factor pathway with coumadin/dipyridamole versus ticlopidine as adjunct antithrombotic-drug regimen in coronary artery stenting.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2003, Volume: 14, Issue:4

    Topics: Adult; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; C

2003
Safety of early intravenous dipyridamole technetium 99m sestamibi SPECT myocardial perfusion imaging after uncomplicated first myocardial infarction. Early Post MI IV Dipyridamole Study (EPIDS).
    American heart journal, 1997, Volume: 134, Issue:1

    Topics: Angina, Unstable; Blood Pressure; Coronary Circulation; Death, Sudden, Cardiac; Dipyridamole; Electr

1997
[Intracoronary dipyridamole reduces the incidence of acute coronary vessel occlusion in percutaneous transluminal coronary angioplasty--a prospective randomized study].
    Zeitschrift fur Kardiologie, 1997, Volume: 86, Issue:12

    Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Coro

1997
Adjunctive intracoronary dipyridamole in the interventional treatment of small coronary arteries: a prospectively randomized trial.
    American heart journal, 2000, Volume: 139, Issue:6

    Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Thrombosis; Coronar

2000
[Anticoagulantion and antiaggregation therapy in patients with unstableangina pectoris].
    Vnitrni lekarstvi, 1990, Volume: 36, Issue:6

    Topics: Angina, Unstable; Aspirin; Dipyridamole; Drug Therapy, Combination; Electrocardiography; Female; Hep

1990
Comparative study of heparin and antiplatelets in treatment of preinfarction angina.
    Cardiologia (Rome, Italy), 1989, Volume: 34, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Aspirin; Clinical Trials as Topic; Dipyridamole; Dru

1989
Prevention of coronary heart disease in practice. Implications of the results of recent clinical trials.
    JAMA, 1985, Jul-12, Volume: 254, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina, Unstable; Aspirin; Blood Platelets; Cholesterol; C

1985
Clinical trials of antiplatelet drug therapy in acute myocardial infarction, unstable angina, and aortocoronary bypass surgery.
    Cardiovascular clinics, 1987, Volume: 18, Issue:1

    Topics: Angina Pectoris; Angina, Unstable; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Arte

1987
Antithrombotic agents in coronary artery disease.
    Chest, 1986, Volume: 89, Issue:2 Suppl

    Topics: Angina, Unstable; Anticoagulants; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Disea

1986
Aspirin for the prevention of coronary thrombosis: current facts and perspectives.
    European heart journal, 1986, Volume: 7, Issue:6

    Topics: Angina, Unstable; Animals; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disea

1986

Other Studies

27 other studies available for dipyridamole and Angina at Rest

ArticleYear
Pituitary apoplexy after myocardial perfusion scintigraphy.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10

    Topics: Adenoma; Aged; Angina, Unstable; Anticoagulants; Cardiac Pacing, Artificial; Dipyridamole; Female; H

2012
Risk stratification by stress echocardiography: a whiter shade of pale?
    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2004, Volume: 5, Issue:3

    Topics: Angina, Unstable; Dipyridamole; Echocardiography, Stress; Humans; Prognosis; Risk Assessment

2004
Identifying patients without favourable long-term outcome among those with medically stabilized unstable angina and a negative dipyridamole stress echocardiogram.
    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2004, Volume: 5, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Dipyridamole; Echocardiography, Stress; Female; Fo

2004
Prognostic value of combined perfusion and function by stress technetium-99m sestamibi gated SPECT myocardial perfusion imaging in patients with suspected or known coronary artery disease.
    The American journal of cardiology, 2005, Jun-01, Volume: 95, Issue:11

    Topics: Aged; Angina, Unstable; Coronary Angiography; Coronary Disease; Dipyridamole; Exercise Test; Female;

2005
Incremental diagnostic value of ultrasonographic assessment of coronary flow reserve with high-dose dipyridamole in patients with acute coronary syndrome.
    International journal of cardiology, 2006, Jan-26, Volume: 106, Issue:3

    Topics: Aged; Angina, Unstable; Blood Flow Velocity; Coronary Circulation; Coronary Stenosis; Dipyridamole;

2006
The additive prognostic value of wall motion abnormalities and coronary flow reserve during dipyridamole stress echo.
    European heart journal, 2008, Volume: 29, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Coronary Artery Disease; Coronary Circulation; Dea

2008
[Antiplatelet treatment after acute and chronic ischemic heart and brain events is insufficient according to recommendations].
    Ugeskrift for laeger, 2008, Mar-31, Volume: 170, Issue:14

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Aspirin;

2008
Unstable angina in a patient with mucocutaneous lymph node syndrome.
    Japanese heart journal, 1984, Volume: 25, Issue:4

    Topics: Aneurysm; Angina Pectoris; Angina, Unstable; Aspirin; Child; Coronary Angiography; Coronary Artery B

1984
Prognostic value of predischarge dipyridamole technetium 99m sestamibi myocardial tomography in medically treated patients with unstable angina.
    American heart journal, 1995, Volume: 130, Issue:4

    Topics: Angina, Unstable; Dipyridamole; Exercise Test; Humans; Prognosis; Proportional Hazards Models; Survi

1995
[Safety of the dipyramidole echocardiography test in elderly coronary disease patients].
    Minerva cardioangiologica, 1993, Volume: 41, Issue:5

    Topics: Age Factors; Aged; Angina, Unstable; Coronary Disease; Dipyridamole; Dose-Response Relationship, Dru

1993
Extent of jeopardized viable myocardium determined by myocardial perfusion imaging best predicts perioperative cardiac events in patients undergoing noncardiac surgery.
    Journal of the American College of Cardiology, 1993, Volume: 21, Issue:2

    Topics: Aged; Angina, Unstable; Cohort Studies; Death, Sudden, Cardiac; Diabetes Mellitus; Dipyridamole; Fem

1993
Dipyridamole technetium 99m sestamibi myocardial tomography for preoperative cardiac risk stratification before major or minor nonvascular surgery.
    American heart journal, 1996, Volume: 132, Issue:3

    Topics: Aged; Angina, Unstable; Coronary Circulation; Coronary Disease; Death, Sudden, Cardiac; Dipyridamole

1996
Cardiac assessment prior to vascular surgery: is dipyridamole-sestamibi necessary?
    Annals of vascular surgery, 1996, Volume: 10, Issue:4

    Topics: Age Factors; Aged; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Coronary Arter

1996
Relevance of increased lung thallium uptake on stress imaging in patients with unstable angina and non-Q wave myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI)-IIIB Study.
    Journal of the American College of Cardiology, 1997, Volume: 30, Issue:2

    Topics: Angina, Unstable; Body Weight; Cardiac Catheterization; Dipyridamole; Exercise Tolerance; Female; Fo

1997
Relation of gender to physician use of test results and to the prognostic value of stress technetium 99m sestamibi myocardial single-photon emission computed tomography scintigraphy.
    American heart journal, 1997, Volume: 134, Issue:1

    Topics: Angina Pectoris; Angina, Unstable; Cardiac Catheterization; Coronary Disease; Death, Sudden, Cardiac

1997
Myocardial rest iodine-123-beta-methyl-iodophenyl-pentadecanoic acid scintigraphy compared with dipyridamole stress thallium-201 scintigraphy in unstable angina.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:1

    Topics: Angina Pectoris; Angina, Unstable; Dipyridamole; Fatty Acids; Humans; Iodine Radioisotopes; Iodobenz

1998
Prognostic value of dipyridamole-thallium myocardial scintigraphy in patients with Kawasaki disease.
    Circulation, 1998, Sep-08, Volume: 98, Issue:10

    Topics: Age of Onset; Angina, Unstable; Blood Pressure; Child; Coronary Angiography; Coronary Artery Bypass;

1998
Vasodilator stress echocardiography for risk stratification of medically stabilized unstable angina.
    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2002, Volume: 3, Issue:1

    Topics: Aged; Angina, Unstable; Atropine; Dipyridamole; Echocardiography, Stress; Electrocardiography; Femal

2002
Dipyridamole perfusion scintigraphy: the experience with its application in one hundred seventy patients with known or suspected unstable angina.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 1

    Topics: Adult; Aged; Angina, Unstable; Chi-Square Distribution; Coronary Angiography; Dipyridamole; Female;

1991
Prognostic value of intravenous dipyridamole thallium scintigraphy after an acute myocardial ischemic event.
    The American journal of cardiology, 1989, Jul-15, Volume: 64, Issue:3

    Topics: Aged; Angina Pectoris; Angina, Unstable; Dipyridamole; Electrocardiography; Follow-Up Studies; Human

1989
Dipyridamole-induced myocardial ischemia.
    JAMA, 1987, Mar-20, Volume: 257, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon; Coronary Ar

1987
Secondary prevention of vascular disease by prolonged antiplatelet treatment. Antiplatelet Trialists' Collaboration.
    British medical journal (Clinical research ed.), 1988, Jan-30, Volume: 296, Issue:6618

    Topics: Angina Pectoris; Angina, Unstable; Aspirin; Cerebrovascular Disorders; Dipyridamole; Drug Combinatio

1988
Cardiac arrest during dipyridamole imaging.
    Chest, 1988, Volume: 93, Issue:5

    Topics: Aged; Angina, Unstable; Dipyridamole; Female; Heart; Heart Arrest; Humans; Myocardial Infarction; Ra

1988
[Localization and quantification of ischemic myocardial areas in the postinfarct phase by dipyridamole 201thallium emission computerized tomography].
    Zeitschrift fur Kardiologie, 1986, Volume: 75, Issue:9

    Topics: Angina, Unstable; Coronary Circulation; Coronary Disease; Dipyridamole; Female; Humans; Male; Middle

1986
[Comparative analysis of the information value of electrocardiographic loading tests in relation to the characteristics of atherosclerotic lesions of the coronary arteries].
    Kardiologiia, 1987, Volume: 27, Issue:4

    Topics: Adult; Angina Pectoris; Angina, Unstable; Cardiac Pacing, Artificial; Coronary Angiography; Coronary

1987
Significance of perfusion studies in the detection of transient myocardial ischemia.
    The Canadian journal of cardiology, 1986, Volume: Suppl A

    Topics: Angina Pectoris; Angina, Unstable; Coronary Disease; Coronary Vessels; Dipyridamole; Heart; Humans;

1986
Dipyridamole-echocardiography test as a clue for assessing the organic 'ceiling' of individual coronary reserve.
    European heart journal, 1987, Volume: 8, Issue:1

    Topics: Adult; Angina Pectoris; Angina, Unstable; Blood Pressure; Coronary Angiography; Coronary Disease; Di

1987