dipyridamole has been researched along with Angina Pectoris with Normal Coronary Arteriogram in 32 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1), with left ventricular hypertrophy, typical angina pectoris, ischemia that can be induced by exercise-electrocardiography test, without previous myocardial infarction, myocardial revascularization or diabetes mellitus, underwent dipyridamole-echocardiography test, thallium exercise myocardial scintigraphy and coronarography." | 9.08 | [Dipyridamole-echocardiography and thallium exercise myocardial scintigraphy in the diagnosis of obstructive coronary or microvascular disease in hypertensive patients with left ventricular hypertrophy and angina]. ( Astarita, C; Gambardella, S; Liguori, E; Maresca, FS; Nicolai, E; Rumolo, S, 1998) |
| "In asymptomatic essential hypertensive patients with angiographically normal coronary arteries and without left ventricular hypertrophy, dipyridamole-induced ischemic-like ST segment depression may be a marker of coronary microvascular disease." | 5.08 | Presence of cardiovascular structural changes in essential hypertensive patients with coronary microvascular disease and effects of long-term treatment. ( Di Legge, V; Ghiadoni, L; Lucarini, A; Salvetti, A; Taddei, S; Virdis, A, 1996) |
| "1), with left ventricular hypertrophy, typical angina pectoris, ischemia that can be induced by exercise-electrocardiography test, without previous myocardial infarction, myocardial revascularization or diabetes mellitus, underwent dipyridamole-echocardiography test, thallium exercise myocardial scintigraphy and coronarography." | 5.08 | [Dipyridamole-echocardiography and thallium exercise myocardial scintigraphy in the diagnosis of obstructive coronary or microvascular disease in hypertensive patients with left ventricular hypertrophy and angina]. ( Astarita, C; Gambardella, S; Liguori, E; Maresca, FS; Nicolai, E; Rumolo, S, 1998) |
| "In 16 patients with chest pain and angiographically normal coronary arteries, CFR was measured using transthoracic echo-Doppler by inducing hyperemia through dipyridamole infusion." | 3.85 | Coronary flow reserve/diastolic function relationship in angina-suffering patients with normal coronary angiography. ( Anchisi, C; Bellacosa, I; Grossini, E; Marino, P; Marti, G; Mary, D; Vacca, G, 2017) |
| "In patients with IHD, administration of dipyridamole induces myocardial ischemia resulting in modification of plasma levels of the soluble adhesion molecules." | 3.70 | The effects of dipyridamole stress test on plasma levels of soluble adhesion molecules intracellular adhesion molecule-1, vascular cell adhesion molecule-1, E-selectin and L-selectin in patients with ischemic heart disease and patients with syndrome X. ( Kalawski, R; Kaźmierczak, M; Rzeźniczak, J; Siminiak, T; Smielecki, J; Wysocki, H, 1999) |
| "Sixty-three patients with known cardiac syndrome X were divided into dipyridamole (201)Tl SPECT myocardial imaging group (group 1, n = 35) and exercise myocardial (99)Tc(m)-MIBI-SPECT imaging group (group 2, n = 28) and the diagnostic accuracy rates were compared." | 2.74 | [The diagnostic value of dipyridamole (201)Tl-SPECT myocardial imaging and exercise myocardial (99)Tc(m)-MIBI-SPECT imaging on detecting cardiac syndrome X]. ( Chen, L; Jiang, JQ; Lin, QR; Luo, M; Wang, JM; Wei, M, 2009) |
| "Microvascular angina is characterized by ischemia-like symptoms in patients with normal coronary arteries and reduced coronary flow reserve." | 2.68 | Effect of diltiazem on coronary flow reserve in patients with microvascular angina. ( Hess, OM; Mayer, I; Oechslin, E; Sütsch, G, 1995) |
| "Dipyridamole BSPM is a promising noninvasive diagnostic modality to differentiate patients with Sy X from those with CAD." | 1.31 | Dipyridamole body surface potential mapping: noninvasive differentiation of syndrome X from coronary artery disease. ( Anger, Z; Aschermann, M; Boudik, F; Tomecková, M; Vojácek, J, 2002) |
| "Nineteen patients with NIDDM and microvascular angina, 18 patients with NIDDM and CAD, and 17 age-matched control subjects were studied." | 1.31 | Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease. ( Nagai, R; Ohtake, T; Ohtomo, K; Shin, WS; Yamada, N; Yang, W; Yokoyama, I; Yonekura, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (50.00) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 3 (9.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mandoli, GE | 1 |
| Cameli, M | 1 |
| Minardi, S | 1 |
| Crudele, F | 1 |
| Lunghetti, S | 1 |
| Mondillo, S | 1 |
| Anchisi, C | 1 |
| Marti, G | 1 |
| Bellacosa, I | 1 |
| Mary, D | 1 |
| Vacca, G | 1 |
| Marino, P | 1 |
| Grossini, E | 1 |
| Mygind, ND | 1 |
| Michelsen, MM | 1 |
| Pena, A | 1 |
| Frestad, D | 1 |
| Dose, N | 1 |
| Aziz, A | 1 |
| Faber, R | 1 |
| Høst, N | 1 |
| Gustafsson, I | 1 |
| Hansen, PR | 1 |
| Hansen, HS | 1 |
| Bairey Merz, CN | 1 |
| Kastrup, J | 1 |
| Prescott, E | 1 |
| Jiang, JQ | 1 |
| Chen, L | 1 |
| Lin, QR | 1 |
| Wang, JM | 1 |
| Luo, M | 1 |
| Wei, M | 1 |
| Boudik, F | 1 |
| Anger, Z | 1 |
| Aschermann, M | 1 |
| Vojácek, J | 1 |
| Tomecková, M | 1 |
| De Lorenzo, A | 1 |
| Lima, RS | 1 |
| Siqueira-Filho, AG | 1 |
| Pantoja, MR | 1 |
| Ishihara, T | 1 |
| Tamoto, S | 1 |
| Takada, K | 1 |
| Ohsawa, N | 1 |
| Jessurun, GA | 2 |
| Hautvast, RW | 1 |
| Tio, RA | 1 |
| DeJongste, MJ | 2 |
| Masci, PG | 1 |
| Laclaustra, M | 1 |
| Lara, JG | 1 |
| Kaski, JC | 1 |
| Sicari, R | 1 |
| Palinkas, A | 2 |
| Pasanisi, EG | 1 |
| Venneri, L | 2 |
| Picano, E | 2 |
| Marwick, TH | 1 |
| de Vries, J | 1 |
| Jager, PL | 1 |
| Staal, MJ | 1 |
| Slart, RH | 1 |
| Zehetgruber, M | 1 |
| Mundigler, G | 1 |
| Christ, G | 1 |
| Mörtl, D | 1 |
| Probst, P | 1 |
| Baumgartner, H | 1 |
| Maurer, G | 1 |
| Siostrzonek, P | 1 |
| Sambuceti, G | 1 |
| Giorgetti, A | 1 |
| Gimelli, A | 1 |
| Marzullo, P | 1 |
| Neglia, D | 1 |
| Salvadori, P | 1 |
| L'Abbate, A | 1 |
| Parodi, O | 1 |
| Holdright, DR | 1 |
| Lindsay, DC | 1 |
| Clarke, D | 1 |
| Fox, K | 1 |
| Poole-Wilson, PA | 1 |
| Collins, P | 1 |
| Palleschi, L | 1 |
| Gianni, W | 1 |
| De Vincentis, G | 1 |
| Banci, M | 1 |
| Sottosanti, G | 1 |
| Ierardi, M | 1 |
| Scopinaro, F | 1 |
| Marigliano, V | 1 |
| Virdis, A | 1 |
| Ghiadoni, L | 1 |
| Lucarini, A | 1 |
| Di Legge, V | 1 |
| Taddei, S | 1 |
| Salvetti, A | 1 |
| Sütsch, G | 1 |
| Oechslin, E | 1 |
| Mayer, I | 1 |
| Hess, OM | 1 |
| Langes, K | 1 |
| Beuthien-Baumann, B | 1 |
| Lübeck, M | 1 |
| Fuchs, C | 1 |
| Schneider, MA | 1 |
| Volk, C | 1 |
| Nienaber, CA | 1 |
| Meeder, JG | 1 |
| Blanksma, PK | 1 |
| van der Wall, EE | 1 |
| Willemsen, AT | 1 |
| Pruim, J | 1 |
| Anthonio, RL | 1 |
| de Jong, RM | 1 |
| Vaalburg, W | 1 |
| Lie, KI | 1 |
| Astarita, C | 1 |
| Nicolai, E | 1 |
| Liguori, E | 1 |
| Gambardella, S | 1 |
| Rumolo, S | 1 |
| Maresca, FS | 1 |
| Planca, E | 1 |
| Alberzoni, A | 1 |
| Fea, F | 1 |
| Colombo, G | 1 |
| Buus, NH | 1 |
| Bøttcher, M | 2 |
| Bøttker, HE | 1 |
| Sørensen, KE | 1 |
| Nielsen, TT | 2 |
| Mulvany, MJ | 1 |
| Botker, HE | 1 |
| Sonne, H | 1 |
| Czernin, J | 1 |
| Siminiak, T | 1 |
| Smielecki, J | 1 |
| Rzeźniczak, J | 1 |
| Kaźmierczak, M | 1 |
| Kalawski, R | 1 |
| Wysocki, H | 1 |
| Sakata, K | 1 |
| Nakamura, T | 1 |
| Tamekiyo, H | 1 |
| Obayashi, K | 1 |
| Ishikawa, J | 1 |
| Nawada, R | 1 |
| Yoshida, H | 1 |
| Shirotani, M | 1 |
| Amano, Y | 1 |
| Hayashi, H | 1 |
| Ishihara, M | 1 |
| Kumazaki, T | 1 |
| Yokoyama, I | 1 |
| Yonekura, K | 1 |
| Ohtake, T | 1 |
| Yang, W | 1 |
| Shin, WS | 1 |
| Yamada, N | 1 |
| Ohtomo, K | 1 |
| Nagai, R | 1 |
| Chen, JW | 1 |
| Hsu, NW | 1 |
| Ting, CT | 1 |
| Lin, SJ | 1 |
| Chang, MS | 1 |
| Ortega, A | 1 |
| Moreno, R | 1 |
| Alonso, JC | 1 |
| Domínguez, P | 1 |
| Almoguera, I | 1 |
| Bittini, A | 1 |
| Lampreave, JL | 1 |
| Suárez, M | 1 |
| Gómez, A | 1 |
| Martínez, L | 1 |
| Sosa, V | 1 |
| Sarnago, F | 1 |
| García-Fernández, MA | 1 |
| Pérez-Vázquez, JM | 1 |
| Rosen, SD | 1 |
| Rigo, F | 1 |
| Pratali, L | 1 |
| Cutaia, V | 1 |
| Raviele, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comprehensive Treatment of Angina in Women With Microvascular Dysfunction - a Proof of Concept Study of the iPower Cohort[NCT02910154] | 62 participants (Actual) | Interventional | 2016-12-31 | Completed | |||
| Microvascular Angina Intervention With Compound Danshen Dripping Pill (MAIDS)[NCT06092736] | Phase 4 | 100 participants (Anticipated) | Interventional | 2018-12-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for dipyridamole and Angina Pectoris with Normal Coronary Arteriogram
| Article | Year |
|---|---|
[Coronary flow reserve and myocardial metabolism in patients with syndrome X].
Topics: Coronary Circulation; Dipyridamole; Exercise Test; Humans; Microvascular Angina; Myocardium | 1994 |
7 trials available for dipyridamole and Angina Pectoris with Normal Coronary Arteriogram
| Article | Year |
|---|---|
[The diagnostic value of dipyridamole (201)Tl-SPECT myocardial imaging and exercise myocardial (99)Tc(m)-MIBI-SPECT imaging on detecting cardiac syndrome X].
Topics: Adult; Aged; Dipyridamole; Exercise Test; Female; Humans; Male; Microvascular Angina; Middle Aged; T | 2009 |
Electrical neuromodulation improves myocardial perfusion and ameliorates refractory angina pectoris in patients with syndrome X: fad or future?
Topics: Adult; Angina Pectoris; Coronary Circulation; Dipyridamole; Female; Humans; Male; Microvascular Angi | 2003 |
Presence of cardiovascular structural changes in essential hypertensive patients with coronary microvascular disease and effects of long-term treatment.
Topics: Acetylcholine; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Coronary Circulation; Dip | 1996 |
Effect of diltiazem on coronary flow reserve in patients with microvascular angina.
Topics: Analysis of Variance; Blood Flow Velocity; Calcium Channel Blockers; Coronary Circulation; Diltiazem | 1995 |
[Dipyridamole-echocardiography and thallium exercise myocardial scintigraphy in the diagnosis of obstructive coronary or microvascular disease in hypertensive patients with left ventricular hypertrophy and angina].
Topics: Adult; Aged; Angina Pectoris; Cardiomyopathy, Hypertrophic; Coronary Disease; Dipyridamole; Echocard | 1998 |
Endothelium-dependent and -independent perfusion reserve and the effect of L-arginine on myocardial perfusion in patients with syndrome X.
Topics: Arginine; Blood Pressure; Cold Temperature; Coronary Circulation; Dipyridamole; Endothelium, Vascula | 1999 |
Coronary flow reserve and brachial artery reactivity in patients with chest pain and "false positive" exercise-induced ST-segment depression.
Topics: Blood Flow Velocity; Brachial Artery; Chest Pain; Contrast Media; Coronary Angiography; Coronary Cir | 2002 |
24 other studies available for dipyridamole and Angina Pectoris with Normal Coronary Arteriogram
| Article | Year |
|---|---|
Layer-specific strain in dipyridamole stress echo: A new tool for the diagnosis of microvascular angina.
Topics: Aged; Dipyridamole; Echocardiography, Stress; Female; Follow-Up Studies; Heart Ventricles; Humans; M | 2018 |
Coronary flow reserve/diastolic function relationship in angina-suffering patients with normal coronary angiography.
Topics: Aged; Biomechanical Phenomena; Blood Flow Velocity; Coronary Angiography; Coronary Vessels; Diastole | 2017 |
Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease: The iPOWER Study.
Topics: Age Factors; Aged; Chi-Square Distribution; Coronary Angiography; Coronary Circulation; Coronary Ves | 2016 |
Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease: The iPOWER Study.
Topics: Age Factors; Aged; Chi-Square Distribution; Coronary Angiography; Coronary Circulation; Coronary Ves | 2016 |
Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease: The iPOWER Study.
Topics: Age Factors; Aged; Chi-Square Distribution; Coronary Angiography; Coronary Circulation; Coronary Ves | 2016 |
Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease: The iPOWER Study.
Topics: Age Factors; Aged; Chi-Square Distribution; Coronary Angiography; Coronary Circulation; Coronary Ves | 2016 |
Dipyridamole body surface potential mapping: noninvasive differentiation of syndrome X from coronary artery disease.
Topics: Body Surface Potential Mapping; Coronary Angiography; Coronary Disease; Diagnosis, Differential; Dip | 2002 |
Prevalence and prognostic value of perfusion defects detected by stress technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography in asymptomatic patients with diabetes mellitus and no known coronary artery disease.
Topics: Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic A | 2002 |
Brachial artery flow-mediated dilation and myocardial perfusion in patients with cardiac syndrome X.
Topics: Brachial Artery; Coronary Circulation; Dipyridamole; Electrocardiography; Endothelium, Vascular; Fem | 2005 |
Long-term survival of patients with chest pain syndrome and angiographically normal or near-normal coronary arteries: the additional prognostic value of dipyridamole echocardiography test (DET).
Topics: Coronary Angiography; Coronary Vessels; Dipyridamole; Echocardiography, Stress; Female; Humans; Male | 2005 |
Ischaemia and outcome with normal coronary arteries.
Topics: Coronary Angiography; Dipyridamole; Echocardiography, Stress; Humans; Microvascular Angina; Vasodila | 2005 |
Myocardial perfusion quantification in patients suspected of cardiac syndrome X with positive and negative exercise testing: a [13N]ammonia positron emission tomography study.
Topics: Adult; Ammonia; Diagnostic Imaging; Dipyridamole; Exercise Test; Female; Humans; Male; Microvascular | 2006 |
Estimation of coronary flow reserve by transesophageal coronary sinus Doppler measurements in patients with syndrome X and patients with significant left coronary artery disease.
Topics: Blood Flow Velocity; Coronary Circulation; Coronary Disease; Dipyridamole; Echocardiography, Doppler | 1995 |
[Global change in the regulation of regional coronary flow in patients with single vessel coronary disease evidenced by positron emission tomography].
Topics: Aged; Angina Pectoris; Coronary Angiography; Coronary Circulation; Coronary Disease; Dipyridamole; F | 1994 |
Coronary flow reserve in patients with chest pain and normal coronary arteries.
Topics: Adenosine; Adult; Aged; Coronary Angiography; Coronary Circulation; Dipyridamole; Exercise Test; Fem | 1993 |
Dipyridamole technetium-99m Sestamibi imaging in the diagnosis of syndrome X.
Topics: Dipyridamole; Female; Humans; Microvascular Angina; Middle Aged; Radionuclide Imaging; Technetium Tc | 1996 |
[Impairment of myocardial perfusion reserve in microvascular angina (syndrome X): assessment by 99mTc-MIBI-SPECT].
Topics: Blood Pressure; Chest Pain; Dipyridamole; Female; Heart; Heart Rate; Humans; Male; Microvascular Ang | 1996 |
Coronary vasomotion in patients with syndrome X: evaluation with positron emission tomography and parametric myocardial perfusion imaging.
Topics: Adult; Cold Temperature; Coronary Disease; Coronary Vessels; Dipyridamole; Endothelium, Vascular; Fe | 1997 |
[Usefulness of stress echocardiography in the diagnosis of syndrome X].
Topics: Aged; Coronary Angiography; Dipyridamole; Echocardiography; Electrocardiography; Evaluation Studies | 1998 |
Reduced vasodilator capacity in syndrome X related to structure and function of resistance arteries.
Topics: Arteries; Case-Control Studies; Coronary Circulation; Dipyridamole; Female; Forearm; Hemodynamics; H | 1999 |
The effects of dipyridamole stress test on plasma levels of soluble adhesion molecules intracellular adhesion molecule-1, vascular cell adhesion molecule-1, E-selectin and L-selectin in patients with ischemic heart disease and patients with syndrome X.
Topics: Adult; Cell Adhesion Molecules; Diagnosis, Differential; Dipyridamole; E-Selectin; Enzyme-Linked Imm | 1999 |
Pseudoxanthoma elasticum with dipyridamole-induced coronary artery spasm: a case report.
Topics: Coronary Angiography; Coronary Disease; Dipyridamole; Female; Humans; Microvascular Angina; Middle A | 1999 |
Coronary flow reserve estimated with fast cine phase-contrast magnetic resonance imaging in 4 patients with syndrome X: technical note.
Topics: Aged; Blood Flow Velocity; Coronary Circulation; Dipyridamole; Female; Humans; Image Enhancement; Ma | 1999 |
Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease.
Topics: Adult; Aged; Blood Glucose; Coronary Angiography; Coronary Circulation; Coronary Disease; Diabetes M | 2000 |
Differential coronary hemodynamics and left ventricular contractility in patients with syndrome X.
Topics: Adult; Aged; Analysis of Variance; Basal Metabolism; Cardiac Catheterization; Coronary Angiography; | 2000 |
[Results of myocardial scintigraphy with 99mTc-tetrofosmin and dipyridamole administration in patients diagnosed of microvascular angina].
Topics: Coronary Circulation; Dipyridamole; Female; Heart; Humans; Male; Microvascular Angina; Middle Aged; | 2000 |
The pathophysiology of cardiac syndrome X--a tale of paradigm shifts.
Topics: 3-Iodobenzylguanidine; Adenosine; Coronary Disease; Dipyridamole; Heart Rate; Humans; Microvascular | 2001 |