Page last updated: 2024-10-26

dipyridamole and Allergic Encephalomyelitis

dipyridamole has been researched along with Allergic Encephalomyelitis in 2 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"Dipyridamole is an inhibitor of microglia activation and may have a role in MS and other neurological conditions to attenuate microglial activity."5.39Reduction of microglial activity in a model of multiple sclerosis by dipyridamole. ( Hader, W; Metz, LM; Sloka, S; Starreveld, Y; Yong, VW, 2013)
"Dipyridamole is an inhibitor of microglia activation and may have a role in MS and other neurological conditions to attenuate microglial activity."1.39Reduction of microglial activity in a model of multiple sclerosis by dipyridamole. ( Hader, W; Metz, LM; Sloka, S; Starreveld, Y; Yong, VW, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sunke, R1
Bankala, R1
Thirupataiah, B1
Ramarao, EVVS1
Kumar, JS1
Doss, HM1
Medishetti, R1
Kulkarni, P1
Kapavarapu, RK1
Rasool, M1
Mudgal, J1
Mathew, JE1
Shenoy, GG1
Parsa, KVL1
Pal, M1
Sloka, S1
Metz, LM1
Hader, W1
Starreveld, Y1
Yong, VW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Controlled Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis[NCT02493049]Phase 217 participants (Actual)Interventional2015-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for dipyridamole and Allergic Encephalomyelitis

ArticleYear
InCl
    European journal of medicinal chemistry, 2019, Jul-15, Volume: 174

    Topics: Animals; Arthritis; Cyclic Nucleotide Phosphodiesterases, Type 4; Encephalomyelitis, Autoimmune, Exp

2019
Reduction of microglial activity in a model of multiple sclerosis by dipyridamole.
    Journal of neuroinflammation, 2013, Jul-18, Volume: 10

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Cytokin

2013