dipyridamole has been researched along with Allergic Encephalomyelitis in 2 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dipyridamole is an inhibitor of microglia activation and may have a role in MS and other neurological conditions to attenuate microglial activity." | 5.39 | Reduction of microglial activity in a model of multiple sclerosis by dipyridamole. ( Hader, W; Metz, LM; Sloka, S; Starreveld, Y; Yong, VW, 2013) |
| "Dipyridamole is an inhibitor of microglia activation and may have a role in MS and other neurological conditions to attenuate microglial activity." | 1.39 | Reduction of microglial activity in a model of multiple sclerosis by dipyridamole. ( Hader, W; Metz, LM; Sloka, S; Starreveld, Y; Yong, VW, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sunke, R | 1 |
| Bankala, R | 1 |
| Thirupataiah, B | 1 |
| Ramarao, EVVS | 1 |
| Kumar, JS | 1 |
| Doss, HM | 1 |
| Medishetti, R | 1 |
| Kulkarni, P | 1 |
| Kapavarapu, RK | 1 |
| Rasool, M | 1 |
| Mudgal, J | 1 |
| Mathew, JE | 1 |
| Shenoy, GG | 1 |
| Parsa, KVL | 1 |
| Pal, M | 1 |
| Sloka, S | 1 |
| Metz, LM | 1 |
| Hader, W | 1 |
| Starreveld, Y | 1 |
| Yong, VW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Controlled Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis[NCT02493049] | Phase 2 | 17 participants (Actual) | Interventional | 2015-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for dipyridamole and Allergic Encephalomyelitis
| Article | Year |
|---|---|
InCl
Topics: Animals; Arthritis; Cyclic Nucleotide Phosphodiesterases, Type 4; Encephalomyelitis, Autoimmune, Exp | 2019 |
Reduction of microglial activity in a model of multiple sclerosis by dipyridamole.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Cytokin | 2013 |